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Volumn 6, Issue 4, 2001, Pages 180-185

Clinical pharmacogenomics: Applications in pharmaceutical R&D

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR; CHOLESTEROL ESTER TRANSFER PROTEIN; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2C19; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; SEROTONIN RECEPTOR;

EID: 0035254858     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(00)01648-2     Document Type: Review
Times cited : (51)

References (24)
  • 1
    • 0006480541 scopus 로고    scopus 로고
    • Weber, W.W. (1997) Chapter 1: Pharmacogenetic Concepts. In Pharmacogenetics, p. 2, Oxford University Press
  • 2
    • 0006480039 scopus 로고    scopus 로고
    • Maugham, W.S. (1938) In The Summing Up, Heinemann Press
  • 4
    • 0006480542 scopus 로고    scopus 로고
    • Kalow, W. (1962) Pharmacogenetics - Heredity and the Responses to Drugs. W.B. Saunders Company
  • 5
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients. A meta-analysis of prospective studies
    • (1998) J. Am. Med. Assoc. , vol.279 , pp. 1200-1205
    • Lazarou, J.1
  • 6
    • 50749093820 scopus 로고
    • The incidence of alcaptonuria: a study in chemical individuality
    • (1902) Lancet. , vol.2 , pp. 1616-1620
    • Garrod, A.E.1
  • 9
    • 0034677966 scopus 로고    scopus 로고
    • Drug discovery: a historical perspective
    • (2000) Science , vol.287 , pp. 1960-1964
    • Drews, J.S.1
  • 11
    • 0026578029 scopus 로고
    • Pitfalls in the drug approval process: dose effect, experimental design and risk-benefit issues
    • (1992) Drug Inf. J. , vol.26 , pp. 251-260
    • Miller, L.1
  • 12
    • 0033782224 scopus 로고    scopus 로고
    • Prospective CYP2D6 genotyping as an exclusion criterion for enrollment of a Phase III clinical trial
    • (2000) Pharmacogenetics , vol.10 , pp. 583-590
    • Murphy, M.P.1
  • 13
    • 0033569516 scopus 로고    scopus 로고
    • Pharmacogenomics: translating functional genomics into rational therapeutics
    • (1999) Science , vol.286 , pp. 487-491
    • Evans, W.E.1
  • 14
    • 0022337949 scopus 로고
    • Extremely rapid hydroxylation of debrisoquine: a case report with implication for treatment with nortryptoline and other tricyclic antidepressants
    • (1985) Ther. Drug Monit. , vol.7 , pp. 478-480
    • Bertilsson, L.1
  • 15
    • 0028260641 scopus 로고
    • The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans
    • (1994) J. Biol. Chem. , vol.269 , pp. 15419-15422
    • De Morais, S.M.F.1
  • 16
    • 0029043462 scopus 로고
    • Interphenotype differences in disposition and effect on gastrin levels of omeprazole - suitability of omeprazole as a probe for CYP2C19
    • (1995) Br. J. Clin. Pharmacol. , vol.39 , pp. 511-518
    • Chang, M.1
  • 18
    • 0032222645 scopus 로고    scopus 로고
    • Characterization of an allelic variant in the nifedipine-specific element of CYP3A4: ethnic distribution and implications for prostate cancer risk
    • (1998) Hum. Mutat. , vol.12 , pp. 289-293
    • Walker, A.H.1
  • 20
    • 0032825907 scopus 로고    scopus 로고
    • Population distribution and effects on drug metabolism of a genetic variant in the 5′ promoter region of CYP3A4
    • (1999) Clin. Pharmacol. Ther. , vol.66 , pp. 288-294
    • Ball, S.E.1
  • 21
    • 0033861614 scopus 로고    scopus 로고
    • CYP3A activity in African American and European American men: population differences and functional effect of the CYP3A4*1B5(-promoter region polymorphism
    • (2000) Clin. Pharmacol. Ther. , vol.68 , pp. 82-91
    • Wandel, C.1
  • 22
    • 0032495541 scopus 로고    scopus 로고
    • The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis
    • (1998) New Engl. J. Med. , vol.338 , pp. 86-93
    • Kuivenhoven, J.A.1
  • 23
    • 0031466866 scopus 로고    scopus 로고
    • Association between genetic polymorphisms of the (2-adrenoceptor and response to albuterol in children with and without a history of wheezing
    • (1997) J. Clin. Invest. , vol.100 , pp. 3184-3188
    • Martinez, F.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.