Fibrinogen-specific antibody induces abdominal aortic aneurysm in mice through complement lectin pathway activation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 46, 2013, Pages

  Zhou, Hui Fang ^a   Yan, Huimin ^a   Bertram, Paula ^a   Hu, Ying ^a   Springer, Luke E ^a   Thompson, Robert W ^a   Curci, John A ^a   Hourcade, Dennis E ^a   Pham, Christine T N ^a  

^a WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; COLLAGEN TYPE 1; ELASTASE; EPITOPE; FIBRINOGEN; FIBRINOGEN ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G2B; LECTIN; MANNAN BINDING LECTIN; MONOCLONAL ANTIBODY; SCLEROPROTEIN; UNCLASSIFIED DRUG;

ABDOMINAL AORTA ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DETECTION; ANTIBODY PRODUCTION; ANTIGEN ANTIBODY COMPLEX; AORTA WALL; ARTICLE; B LYMPHOCYTE; CARBOHYDRATE ANALYSIS; COMPLEMENT ACTIVATION; COMPLEMENT LECTIN PATHWAY; CONTROLLED STUDY; DISEASE COURSE; GLYCOSYLATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOGENESIS; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SPLEEN CELL;

ANALYSIS OF VARIANCE; ANIMALS; AORTIC ANEURYSM, ABDOMINAL; BLOTTING, WESTERN; COMPLEMENT ACTIVATION; COMPLEMENT PATHWAY, MANNOSE-BINDING LECTIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX PROTEINS; FIBRINOGEN; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOGLOBULIN G; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MICE; MICE, INBRED C57BL; PANCREATIC ELASTASE;

EID: 84887501897     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1315512110     Document Type: Article

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