Sex differences in insulin resistance and cardiovascular disease risk

Journal of Clinical Endocrinology and Metabolism

Volumn 98, Issue 11, 2013, Pages

  Kim, Sun H ^a   Reaven, Gerald ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; AGE; AGED; ARTICLE; BODY MASS; CARDIOVASCULAR DISEASE; CROSS-SECTIONAL STUDY; DIASTOLIC BLOOD PRESSURE; FEMALE; GLUCOSE BLOOD LEVEL; HEALTH DISPARITY; HUMAN; INSULIN RESISTANCE; MALE; PRIORITY JOURNAL; SEX DIFFERENCE;

ADULT; AGE DISTRIBUTION; AGED; BLOOD GLUCOSE; CARDIOVASCULAR DISEASES; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INSULIN RESISTANCE; LIPIDS; MALE; MIDDLE AGED; RISK FACTORS; SEX CHARACTERISTICS; SEX DISTRIBUTION; YOUNG ADULT;

EID: 84887488354     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2013-1166     Document Type: Article

References (23)

1. Barrett-Connor EL, Cohn BA, Wingard DL, Edelstein SL. Why is diabetes mellitus a stronger risk factor for fatal ischemic heart disease in women than in men? The Rancho Bernardo Study. JAMA. 1991;265: 627-631.
2. Ervin RB. Prevalence of metabolic syndrome among adults 20 years of age and over, by sex, age, race and ethnicity, and body mass index: United States, 2003-2006. Natl Health Stat Rep. 2009: 1-7.
3. Moran A, Jacobs DR Jr, Steinberger J, et al. Changes in insulin resistance and cardiovascular risk during adolescence: establishment of differential risk in males and females. Circulation. 2008; 117: 2361-2368.
4. Willeit J, Kiechl S, Egger G, et al. The role of insulin in age-related sex differences of cardiovascular risk profile and morbidity. Atherosclerosis. 1997;130: 183-189.
5. Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes. 1988;37: 1595-1607.
6. Yki-Jarvinen H. Sex and insulin sensitivity. Metabolism. 1984;33: 1011-1015.
7. Nuutila P, Knuuti MJ, Mäki M, et al. Gender and insulin sensitivity in the heart and in skeletal muscles. Studies using positron emission tomography. Diabetes. 1995;44: 31-36.
8. Ferrara CM, Goldberg AP, Nicklas BJ, Sorkin JD, Ryan AS. Sex differences in insulin action and body fat distribution in overweight and obese middle-aged and older men and women. Appl Physiol Nutr Metab. 2008;33: 784-790.
9. Cnop M, Havel PJ, Utzschneider KM, et al. Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex. Diabetologia. 2003;46: 459-469.
10. Ferrannini E, Natali A, Bell P, Cavallo-Perin P, Lalic N, Mingrone G. Insulin resistance and hypersecretion in obesity. European Group for the Study of Insulin Resistance (EGIR). J Clin Invest. 1997;100: 1166-1173.
11. Clausen JO, Borch-Johnsen K, Ibsen H, et al. Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population- based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and life-style factors. J Clin Invest. 1996;98: 1195-1209.
12. MancoM,Nolfe G, CalvaniM,et al. Menopause, insulin resistance, and risk factors for cardiovascular disease. Menopause. 2006;13: 809-817.
13. Farin HM, Abbasi F, Reaven GM. Body mass index and waist circumference both contribute to differences in insulin-mediated glucose disposal in nondiabetic adults.AmJ Clin Nutr. 2006;83: 47-51.
14. Pei D, Jones CN, Bhargava R, Chen YD, Reaven GM. Evaluation of octreotide to assess insulin-mediated glucose disposal by the insulin suppression test. Diabetologia. 1994;37: 843-845.
15. Greenfield MS, Doberne L, Kraemer F, Tobey T, Reaven G. Assessment of insulin resistance with the insulin suppression test and the euglycemic clamp. Diabetes. 1981;30: 387-392.
16. Knowles JW, Assimes TL, Tsao PS, et al. Measurement of insulinmediated glucose uptake: direct comparison of the modified insulin suppression test and the euglycemic, hyperinsulinemic clamp. Metabolism. 2013;62(4): 548-553.
17. Lerner DJ, KannelWB.Patterns of coronary heart disease morbidity and mortality in the sexes: a 26-year follow-up of the Framingham population. Am Heart J. 1986;111: 383-390.
18. Berglund L, Brunzell JD, Goldberg AC, et al. Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2012;97: 2969-2989.
19. Kato I, Toniolo P, Akhmedkhanov A, Koenig KL, Shore R, Zeleniuch- Jacquotte A. Prospective study of factors influencing the onset of natural menopause. J Clin Epidemiol. 1998;51: 1271-1276.
20. McLaughlin T, Lamendola C, Liu A, Abbasi F. Preferential fat deposition in subcutaneous versus visceral depots is associated with insulin sensitivity. J Clin Endocrinol Metab. 2011;96:E1756- E1760.
21. Enzi G, Gasparo M, Biondetti PR, Fiore D, Semisa M, Zurlo F. Subcutaneous and visceral fat distribution according to sex, age, and overweight, evaluated by computed tomography. Am J Clin Nutr. 1986;44: 739-746.
22. Abdulnour J, Doucet E, Brochu M, et al. The effect of the menopausal transition on body composition and cardiometabolic risk factors: a Montreal-Ottawa New Emerging Team group study. Menopause. 2012;19: 760-767.
23. Banks K, Lo M, Khera A. Angina in women without obstructive coronary artery disease. Curr Cardiol Rev. 2010;6: 71-81.