메뉴 건너뛰기




Volumn 12, Issue 11, 2013, Pages 2472-2482

Molecular radiotherapy using cleavable radioimmunoconjugates that target eGFR and γH2AX

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY CONJUGATE; ANTINEOPLASTIC AGENT; BENZYL PENTETIC ACID GAMMA HISTONE H2AX ANTIBODY NLS PEPTIDE SS EPIDERMAL GROWTH FACTOR INDIUM 111; BENZYL PENTETIC ACID RABBIT IMMUNOGLOBULIN G NLS PEPTIDE SS EPIDERMAL GROWTH FACTOR INDIUM 111; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; HISTONE GAMMA H2AX; HISTONE H2AX; INDIUM 111; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

EID: 84887468746     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (20)

References (32)
  • 2
    • 84861893199 scopus 로고    scopus 로고
    • Use of the gamma-H2AX assay to monitor DNA damage and repair in translational cancer research
    • Ivashkevich A, Redon CE, Nakamura AJ, Martin RF, Martin OA. Use of the gamma-H2AX assay to monitor DNA damage and repair in translational cancer research. Cancer Lett 2012;327:123-33.
    • (2012) Cancer Lett , vol.327 , pp. 123-133
    • Ivashkevich, A.1    Redon, C.E.2    Nakamura, A.J.3    Martin, R.F.4    Martin, O.A.5
  • 5
    • 84870490971 scopus 로고    scopus 로고
    • Molecular and cellular effects of Auger emitters: 2008-2011
    • Yasui LS. Molecular and cellular effects of Auger emitters: 2008-2011. Int J Radiat Biol 2012;88:864-70.
    • (2012) Int J Radiat Biol , vol.88 , pp. 864-870
    • Yasui, L.S.1
  • 6
    • 0033622156 scopus 로고    scopus 로고
    • 111In-labeled EGF is selectively radiotoxic to human breast cancer cells overexpressing EGFR
    • Reilly RM, Kiarash R, Cameron RG, Porlier N, Sandhu J, Hill RP, et al. 111In-labeled EGF is selectively radiotoxic to human breast cancer cells overexpressing EGFR. J Nucl Med 2000;41:429-38.
    • (2000) J Nucl Med , vol.41 , pp. 429-438
    • Reilly, R.M.1    Kiarash, R.2    Cameron, R.G.3    Porlier, N.4    Sandhu, J.5    Hill, R.P.6
  • 7
    • 0034102191 scopus 로고    scopus 로고
    • A comparison of EGF and MAb 528 labeled with 111In for imaging human breast cancer
    • Reilly RM, Kiarash R, Sandhu J, Lee YW, Cameron RG, Hendler A, et al. A comparison of EGF and MAb 528 labeled with 111In for imaging human breast cancer. J Nucl Med 2000;41:903-11.
    • (2000) J Nucl Med , vol.41 , pp. 903-911
    • Reilly, R.M.1    Kiarash, R.2    Sandhu, J.3    Lee, Y.W.4    Cameron, R.G.5    Hendler, A.6
  • 8
    • 0347926091 scopus 로고    scopus 로고
    • Drug delivery strategy utilizing conjugation via reversible disulfide linkages: Role and site of cellular reducing activities
    • Saito G, Swanson JA, Lee KD. Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities. Adv Drug Deliv Rev 2003;55:199-215.
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 199-215
    • Saito, G.1    Swanson, J.A.2    Lee, K.D.3
  • 9
    • 32944458087 scopus 로고    scopus 로고
    • Strategies for delaying or treating in vivo acquired resistance to trastuzumab in human breast cancer xenografts
    • du Manoir JM, Francia G,ManS, Mossoba M, Medin JA, Viloria-Petit A, et al. Strategies for delaying or treating in vivo acquired resistance to trastuzumab in human breast cancer xenografts. Clin Cancer Res 2006;12:904-16.
    • (2006) Clin Cancer Res , vol.12 , pp. 904-916
    • Du Manoir, J.M.1    Francia, G.2    Man, S.3    Mossoba, M.4    Medin, J.A.5    Viloria-Petit, A.6
  • 10
    • 66249108561 scopus 로고    scopus 로고
    • 111Inlabeled immunoconjugates (ICs) bispecific for the epidermal growth factor receptor (EGFR) and cyclin-dependent kinase inhibitor, p27Kip1
    • Cornelissen B, Kersemans V, McLarty K, Tran L, Reilly RM. 111Inlabeled immunoconjugates (ICs) bispecific for the epidermal growth factor receptor (EGFR) and cyclin-dependent kinase inhibitor, p27Kip1. Cancer Biother Radiopharm 2009;24:163-73.
    • (2009) Cancer Biother Radiopharm , vol.24 , pp. 163-173
    • Cornelissen, B.1    Kersemans, V.2    McLarty, K.3    Tran, L.4    Reilly, R.M.5
  • 12
    • 33845928029 scopus 로고    scopus 로고
    • Cellular penetration and nuclear importation properties of 111In-labeled and 123I-labeled HIV-1 tat peptide immunoconjugates in BT-474 human breast cancer cells
    • Cornelissen B, Hu M, McLarty K, Costantini D, Reilly RM. Cellular penetration and nuclear importation properties of 111In-labeled and 123I-labeled HIV-1 tat peptide immunoconjugates in BT-474 human breast cancer cells. Nucl Med Biol 2007;34:37-46.
    • (2007) Nucl Med Biol , vol.34 , pp. 37-46
    • Cornelissen, B.1    Hu, M.2    McLarty, K.3    Costantini, D.4    Reilly, R.M.5
  • 13
    • 48749131228 scopus 로고    scopus 로고
    • Relationship between induction of phosphorylated H2AX and survival inbreast cancer cells exposed to 111In-DTPA-hEGF
    • Cai Z, Chen Z, Bailey KE, Scollard DA, Reilly RM, Vallis KA. Relationship between induction of phosphorylated H2AX and survival inbreast cancer cells exposed to 111In-DTPA-hEGF. J Nucl Med 2008;49:1353-61.
    • (2008) J Nucl Med , vol.49 , pp. 1353-1361
    • Cai, Z.1    Chen, Z.2    Bailey, K.E.3    Scollard, D.A.4    Reilly, R.M.5    Vallis, K.A.6
  • 14
    • 12344332475 scopus 로고    scopus 로고
    • The amazing world of auger electrons
    • Kassis AI. The amazing world of auger electrons. Int J Radiat Biol 2004;80:789-803.
    • (2004) Int J Radiat Biol , vol.80 , pp. 789-803
    • Kassis, A.I.1
  • 15
    • 78650770785 scopus 로고    scopus 로고
    • Targeting the nucleus: An overview of Augerelectron radionuclide therapy
    • Cornelissen B, Vallis KA. Targeting the nucleus: an overview of Augerelectron radionuclide therapy. Curr Drug Discov Technol 2010;7: 263-79.
    • (2010) Curr Drug Discov Technol , vol.7 , pp. 263-279
    • Cornelissen, B.1    Vallis, K.A.2
  • 18
    • 79951723668 scopus 로고    scopus 로고
    • Improving anticancer activity and selectivity of camptothecin through conjugation with releasable substance P
    • Zhang W, Song J, Mu L, Zhang B, Liu L, Xing Y, et al. Improving anticancer activity and selectivity of camptothecin through conjugation with releasable substance P. Bioorg Med Chem Lett 2011;21: 1452-55.
    • (2011) Bioorg Med Chem Lett , vol.21 , pp. 1452-1455
    • Zhang, W.1    Song, J.2    Mu, L.3    Zhang, B.4    Liu, L.5    Xing, Y.6
  • 19
    • 0034681122 scopus 로고    scopus 로고
    • Enzymatic reduction of disulfide bonds in lysosomes: Characterization of a gamma-interferon- inducible lysosomal thiol reductase (GILT)
    • Arunachalam B, Phan UT, Geuze HJ, Cresswell P. Enzymatic reduction of disulfide bonds in lysosomes: characterization of a gamma-interferon- inducible lysosomal thiol reductase (GILT). Proc Natl Acad Sci U S A 2000;97:745-50.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 745-750
    • Arunachalam, B.1    Phan, U.T.2    Geuze, H.J.3    Cresswell, P.4
  • 20
    • 0024264526 scopus 로고
    • Glutathione metabolism and its selective modification
    • Meister A. Glutathione metabolism and its selective modification. J Biol Chem 1988;263:17205-8.
    • (1988) J Biol Chem , vol.263 , pp. 17205-17208
    • Meister, A.1
  • 21
    • 33748792549 scopus 로고    scopus 로고
    • Evaluation of disulfide reduction during receptor-mediated endocytosis by using FRET imaging
    • Yang J, Chen H, Vlahov IR, Cheng JX, Low PS. Evaluation of disulfide reduction during receptor-mediated endocytosis by using FRET imaging. Proc Natl Acad Sci USA 2006;103:13872-77.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 13872-13877
    • Yang, J.1    Chen, H.2    Vlahov, I.R.3    Cheng, J.X.4    Low, P.S.5
  • 22
    • 34547786032 scopus 로고    scopus 로고
    • (111)In-labeled trastuzumab (Herceptin) modified with nuclear localization sequences (NLS): An Auger electron-emitting radiotherapeutic agent for HER2/ neu-amplified breast cancer
    • Costantini DL, Chan C, Cai Z, Vallis KA, Reilly RM. (111)In-labeled trastuzumab (Herceptin) modified with nuclear localization sequences (NLS): an Auger electron-emitting radiotherapeutic agent for HER2/ neu-amplified breast cancer. J Nucl Med 2007;48:1357-68.
    • (2007) J Nucl Med , vol.48 , pp. 1357-1368
    • Costantini, D.L.1    Chan, C.2    Cai, Z.3    Vallis, K.A.4    Reilly, R.M.5
  • 23
    • 80054764378 scopus 로고    scopus 로고
    • Translocation of HIV TAT peptide and analogues induced by multiplexed membrane and cytoskeletal interactions
    • Mishra A, Lai GH, Schmidt NW, Sun VZ, Rodriguez AR, Tong R, et al. Translocation of HIV TAT peptide and analogues induced by multiplexed membrane and cytoskeletal interactions. Proc Natl Acad Sci USA 2011;108:16883-88.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 16883-16888
    • Mishra, A.1    Lai, G.H.2    Schmidt, N.W.3    Sun, V.Z.4    Rodriguez, A.R.5    Tong, R.6
  • 24
    • 68549110328 scopus 로고    scopus 로고
    • Twenty years of cell-penetrating peptides: From molecular mechanisms to therapeutics
    • Heitz F, Morris MC, Divita G. Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics. Br J Pharmacol 2009; 157:195-206.
    • (2009) Br J Pharmacol , vol.157 , pp. 195-206
    • Heitz, F.1    Morris, M.C.2    Divita, G.3
  • 25
    • 33644827799 scopus 로고    scopus 로고
    • (89)Zr as a PET surrogate radioisotope for scouting biodistribution of the therapeutic radiometals (90)Y and (177)Lu in tumor-bearing nude mice after coupling to the internalizing antibody cetuximab
    • Perk LR, Visser GW, Vosjan MJ, Stigter-van Walsum M, Tijink BM, Leemans CR, et al. (89)Zr as a PET surrogate radioisotope for scouting biodistribution of the therapeutic radiometals (90)Y and (177)Lu in tumor-bearing nude mice after coupling to the internalizing antibody cetuximab. J Nucl Med 2005;46:1898-1906.
    • (2005) J Nucl Med , vol.46 , pp. 1898-1906
    • Perk, L.R.1    Visser, G.W.2    Vosjan, M.J.3    Stigter-Van Walsum, M.4    Tijink, B.M.5    Leemans, C.R.6
  • 26
    • 84874904788 scopus 로고    scopus 로고
    • Inactivation of HNSCC cells by 90Y-labeled cetuximab strictly depends on the number of induced DNA double-strand breaks
    • Saker J, Kriegs M, Zenker M, Heldt JM, Eke I, Pietzsch HJ, et al. Inactivation of HNSCC cells by 90Y-labeled cetuximab strictly depends on the number of induced DNA double-strand breaks. J Nucl Med 2013;54:416-23.
    • (2013) J Nucl Med , vol.54 , pp. 416-423
    • Saker, J.1    Kriegs, M.2    Zenker, M.3    Heldt, J.M.4    Eke, I.5    Pietzsch, H.J.6
  • 27
    • 77955491995 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-targeted radioimmunotherapy of human head and neck cancer xenografts using 90Y-labeled fully human antibody panitumumab
    • Liu Z, Liu Y, Jia B, Zhao H, Jin X, Li F, et al. Epidermal growth factor receptor-targeted radioimmunotherapy of human head and neck cancer xenografts using 90Y-labeled fully human antibody panitumumab. Mol Cancer Ther 2010;9:2297-308.
    • (2010) Mol Cancer Ther , vol.9 , pp. 2297-2308
    • Liu, Z.1    Liu, Y.2    Jia, B.3    Zhao, H.4    Jin, X.5    Li, F.6
  • 28
    • 70349644860 scopus 로고    scopus 로고
    • Intravesical alpha-radioimmunotherapy with 213Bi-anti- EGFR-mAb defeats human bladder carcinoma in xenografted nude mice
    • Pfost B, Seidl C, Autenrieth M, Saur D, Bruchertseifer F, Morgenstern A, et al. Intravesical alpha-radioimmunotherapy with 213Bi-anti- EGFR-mAb defeats human bladder carcinoma in xenografted nude mice. J Nucl Med 2009;50:1700-8.
    • (2009) J Nucl Med , vol.50 , pp. 1700-1708
    • Pfost, B.1    Seidl, C.2    Autenrieth, M.3    Saur, D.4    Bruchertseifer, F.5    Morgenstern, A.6
  • 29
    • 14844359242 scopus 로고    scopus 로고
    • Radiobiologic principles in radionuclide therapy
    • Kassis AI, Adelstein SJ. Radiobiologic principles in radionuclide therapy. J Nucl Med 2005;46 Suppl 1:4S-12S.
    • (2005) J Nucl Med , vol.46 , Issue.1 SUPPL.
    • Kassis, A.I.1    Adelstein, S.J.2
  • 30
    • 0026505912 scopus 로고
    • Immunotherapy of human glioma xenografts with unlabeled, 131I-, or 125I-labeled monoclonal antibody 425 to epidermal growth factor receptor
    • Bender H, Takahashi H, Adachi K, Belser P, Liang SH, Prewett M, et al. Immunotherapy of human glioma xenografts with unlabeled, 131I-, or 125I-labeled monoclonal antibody 425 to epidermal growth factor receptor. Cancer Res 1992;52:121-26.
    • (1992) Cancer Res , vol.52 , pp. 121-126
    • Bender, H.1    Takahashi, H.2    Adachi, K.3    Belser, P.4    Liang, S.H.5    Prewett, M.6
  • 31
    • 73349092778 scopus 로고    scopus 로고
    • Noninternalizing monoclonal antibodies are suitable candidates for 125I radioimmunotherapy of small-volume peritoneal carcinomatosis
    • Santoro L, Boutaleb S, Garambois V, Bascoul-Mollevi C, Boudousq V, Kotzki PO, et al. Noninternalizing monoclonal antibodies are suitable candidates for 125I radioimmunotherapy of small-volume peritoneal carcinomatosis. J Nucl Med 2009;50:2033-41.
    • (2009) J Nucl Med , vol.50 , pp. 2033-2041
    • Santoro, L.1    Boutaleb, S.2    Garambois, V.3    Bascoul-Mollevi, C.4    Boudousq, V.5    Kotzki, P.O.6
  • 32
    • 84865135912 scopus 로고    scopus 로고
    • (1)(1)(1) In-Bn-DTPA-nimotuzumab with/without modification with nuclear translocation sequence (NLS) peptides: An Auger electron-emitting radioimmunotherapeutic agent for EGFR-positive and trastuzumab (Herceptin)-resistant breast cancer
    • Fasih A, Fonge H, Cai Z, Leyton JV, Tikhomirov I, Done SJ, et al. (1)(1)(1) In-Bn-DTPA-nimotuzumab with/without modification with nuclear translocation sequence (NLS) peptides: an Auger electron-emitting radioimmunotherapeutic agent for EGFR-positive and trastuzumab (Herceptin)-resistant breast cancer. Breast Cancer Res Treat 2012; 135:189-200.
    • (2012) Breast Cancer Res Treat , vol.135 , pp. 189-200
    • Fasih, A.1    Fonge, H.2    Cai, Z.3    Leyton, J.V.4    Tikhomirov, I.5    Done, S.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.