-
1
-
-
0030897007
-
Mantle cell lymphoma: A clinicopathologic study of 80 cases
-
Argatoff LH, Connors JM, Klasa RJ, Horsman DE, Gascoyne RD. Mantle cell lymphoma: a clinicopathologic study of 80 cases. Blood1997;89:206778.
-
(1997)
Blood
, vol.89
, pp. 206778
-
-
Argatoff, L.H.1
Connors, J.M.2
Klasa, R.J.3
Horsman, D.E.4
Gascoyne, R.D.5
-
2
-
-
1842413105
-
A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma. The Non-Hodgkin's Lymphoma Classification Project
-
A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma. The Non-Hodgkin's Lymphoma Classification Project. Blood 1997;89:3909-18.
-
(1997)
Blood
, vol.89
, pp. 3909-3918
-
-
-
3
-
-
38549174095
-
Immunotherapy in mantle cell lymphoma: Anti-CD20-based therapy and beyond
-
Zhou Y, Zhang L, Romaguera J, Delasalle K, Han X, Du X, et al. Immunotherapy in mantle cell lymphoma: anti-CD20-based therapy and beyond. Am J Hematol 2008;83:144-9.
-
(2008)
Am J Hematol
, vol.83
, pp. 144-149
-
-
Zhou, Y.1
Zhang, L.2
Romaguera, J.3
Delasalle, K.4
Han, X.5
Du, X.6
-
4
-
-
0029347062
-
New insights into proteasome function: From archaebacteria to drug development
-
Goldberg AL, Stein R, Adams J. New insights into proteasome function: from archaebacteria to drug development. Chem Biol 1995; 2:503-8.
-
(1995)
Chem Biol
, vol.2
, pp. 503-508
-
-
Goldberg, A.L.1
Stein, R.2
Adams, J.3
-
5
-
-
0030016595
-
Structure and functions of the 20S and 26S proteasomes
-
Coux O, Tanaka K, Goldberg AL. Structure and functions of the 20S and 26S proteasomes. Annu Rev Biochem 1996;65:801-47.
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 801-847
-
-
Coux, O.1
Tanaka, K.2
Goldberg, A.L.3
-
9
-
-
2342613652
-
The proteasome: A suitable antineoplastic target
-
Adams J. The proteasome: a suitable antineoplastic target. Nat Rev Cancer 2004;4:349-60.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 349-360
-
-
Adams, J.1
-
10
-
-
23144449789
-
Ubiquitin signalling in the NF-[kappa]
-
Chen ZJ. Ubiquitin signalling in the NF-[kappa]B pathway. Nat Cell Biol 2005;7:758-65.
-
(2005)
B Pathway. Nat Cell Biol
, vol.7
, pp. 758-765
-
-
Chen, Z.J.1
-
11
-
-
61449156563
-
Targeting proteins for destruction by the ubiquitin system: Implications for human pathobiology
-
Schwartz AL, Ciechanover A. Targeting proteins for destruction by the ubiquitin system: implications for human pathobiology. Annu Rev Pharmacol Toxicol 2009;49:73-96.
-
(2009)
Annu Rev Pharmacol Toxicol
, vol.49
, pp. 73-96
-
-
Schwartz, A.L.1
Ciechanover, A.2
-
12
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-kB activity
-
Karin M, Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-kB activity. Annu Rev Immunol 2000;18:621-63.
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
13
-
-
74249122773
-
Heat stress triggers apoptosis by impairing NF-kappaB survival signaling in malignant B cells
-
Belardo G, Piva R, Santoro MG. Heat stress triggers apoptosis by impairing NF-kappaB survival signaling in malignant B cells. Leukemia 2010;24:187-96.
-
(2010)
Leukemia
, vol.24
, pp. 187-196
-
-
Belardo, G.1
Piva, R.2
Santoro, M.G.3
-
14
-
-
77956578834
-
MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: Rationale for treatment of NF-{kappa}B-dependent lymphoma
-
Milhollen MA, Traore T, Adams-Duffy J, Thomas MP, Berger AJ, Dang L, et al. MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-{kappa}B-dependent lymphoma. Blood 2010;116: 1515-23.
-
(2010)
Blood
, vol.116
, pp. 1515-1523
-
-
Milhollen, M.A.1
Traore, T.2
Adams-Duffy, J.3
Thomas, M.P.4
Berger, A.J.5
Dang, L.6
-
15
-
-
80052014052
-
Inflammation meets cancer, with NF-[kappa]B as the matchmaker
-
Ben-Neriah Y, Karin M. Inflammation meets cancer, with NF-[kappa]B as the matchmaker. Nat Immunol 2011;12:715-23.
-
(2011)
Nat Immunol
, vol.12
, pp. 715-723
-
-
Ben-Neriah, Y.1
Karin, M.2
-
16
-
-
3042668006
-
In silico simulation of inhibitor drug effects on nuclear factor-kappaB pathway dynamics
-
Sung MH, Simon R. In silico simulation of inhibitor drug effects on nuclear factor-kappaB pathway dynamics. Mol Pharmacol 2004;66: 70-5.
-
(2004)
Mol Pharmacol
, vol.66
, pp. 70-75
-
-
Sung, M.H.1
Simon, R.2
-
17
-
-
38349053780
-
Bortezomib is synergistic with rituximab and cyclophosphamide inducing apoptosisof mantle cell lymphoma cells in vitro and in vivo
-
Wang M, Han XH, Zhang L, Yang J, Qian JF, Shi YK, et al. Bortezomib is synergistic with rituximab and cyclophosphamide inducing apoptosisof mantle cell lymphoma cells in vitro and in vivo. Leukemia 2008;22:179-85.
-
(2008)
Leukemia
, vol.22
, pp. 179-185
-
-
Wang, M.1
Han, X.H.2
Zhang, L.3
Yang, J.4
Qian, J.F.5
Shi, Y.K.6
-
18
-
-
43049115407
-
Bortezomib in mantle cell lymphoma
-
Suh KS, Goy A. Bortezomib in mantle cell lymphoma. Future Oncol 2008;4:149-68.
-
(2008)
Future Oncol
, vol.4
, pp. 149-168
-
-
Suh, K.S.1
Goy, A.2
-
19
-
-
61649094981
-
Bortezomib in patients with relapsed or refractory mantle celllymphoma: Updated time-to-event analyses of the multicenter phase 2 PINNACLE study
-
Goy A, Bernstein SH, Kahl BS, Djulbegovic B, Robertson MJ, de Vos S, et al. Bortezomib in patients with relapsed or refractory mantle celllymphoma: updated time-to-event analyses of the multicenter phase 2 PINNACLE study. Ann Oncol 2009;20:520-5.
-
(2009)
Ann Oncol
, vol.20
, pp. 520-525
-
-
Goy, A.1
Bernstein, S.H.2
Kahl, B.S.3
Djulbegovic, B.4
Robertson, M.J.5
De Vos, S.6
-
20
-
-
33750625445
-
Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma
-
Fisher RI, Bernstein SH, Kahl BS, Djulbegovic B, Robertson MJ, de Vos S, et al. Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma. J Clin Oncol 2006;24: 4867-74.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4867-4874
-
-
Fisher, R.I.1
Bernstein, S.H.2
Kahl, B.S.3
Djulbegovic, B.4
Robertson, M.J.5
De Vos, S.6
-
21
-
-
34447116376
-
Antitumor activity of PR-171, a novel irreversible inhibitor of the proteasome
-
Demo SD, Kirk CJ, Aujay MA, Buchholz TJ, Dajee M, Ho MN, et al. Antitumor activity of PR-171, a novel irreversible inhibitor of the proteasome. Cancer Res 2007;67:6383-91.
-
(2007)
Cancer Res
, vol.67
, pp. 6383-6391
-
-
Demo, S.D.1
Kirk, C.J.2
Aujay, M.A.3
Buchholz, T.J.4
Dajee, M.5
Ho, M.N.6
-
22
-
-
36148944490
-
Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma
-
Kuhn DJ, Chen Q, Voorhees PM, Strader JS, Shenk KD, Sun CM, et al. Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma. Blood 2007;110:3281-90.
-
(2007)
Blood
, vol.110
, pp. 3281-3290
-
-
Kuhn, D.J.1
Chen, Q.2
Voorhees, P.M.3
Strader, J.S.4
Shenk, K.D.5
Sun, C.M.6
-
23
-
-
70350708810
-
Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome
-
Parlati F, Lee SJ, Aujay M, Suzuki E, Levitsky K, Lorens JB, et al. Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome. Blood 2009;114: 3439-47.
-
(2009)
Blood
, vol.114
, pp. 3439-3447
-
-
Parlati, F.1
Lee, S.J.2
Aujay, M.3
Suzuki, E.4
Levitsky, K.5
Lorens, J.B.6
-
24
-
-
72549116835
-
A phase 1 dose escalation study of the safety and pharmacokinetics of the novel proteasome inhibitor carfilzomib (PR-171) in patients with hematologic malignancies
-
O'Connor OA, Stewart AK, Vallone M, Molineaux CJ, Kunkel LA, Gerecitano JF, et al. A phase 1 dose escalation study of the safety and pharmacokinetics of the novel proteasome inhibitor carfilzomib (PR-171) in patients with hematologic malignancies. Clin Cancer Res 2009;15:7085-91.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7085-7091
-
-
O'Connor, O.A.1
Stewart, A.K.2
Vallone, M.3
Molineaux, C.J.4
Kunkel, L.A.5
Gerecitano, J.F.6
-
25
-
-
0024251459
-
The ubiquitous octamer-binding protein Oct- 1 contains a POU domain with a homeo box subdomain
-
Sturm RA, Das G, Herr W. The ubiquitous octamer-binding protein Oct- 1 contains a POU domain with a homeo box subdomain. Genes Dev 1988;2:1582-99.
-
(1988)
Genes Dev
, vol.2
, pp. 1582-1599
-
-
Sturm, R.A.1
Das, G.2
Herr, W.3
-
26
-
-
42249089099
-
A severe combined immunodeficient-hu in vivo mouse model of human primary mantle cell lymphoma
-
Wang M, Zhang L, Han X, Yang J, Qian J, Hong S, et al. A severe combined immunodeficient-hu in vivo mouse model of human primary mantle cell lymphoma. Clin Cancer Res 2008;14: 2154-60.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 2154-2160
-
-
Wang, M.1
Zhang, L.2
Han, X.3
Yang, J.4
Qian, J.5
Hong, S.6
-
27
-
-
0029950290
-
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease
-
Susin SA, Zamzami N, Castedo M, Hirsch T, Marchetti P, Macho A, et al. Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J Exp Med 1996;184:1331-41.
-
(1996)
J Exp Med
, vol.184
, pp. 1331-1341
-
-
Susin, S.A.1
Zamzami, N.2
Castedo, M.3
Hirsch, T.4
Marchetti, P.5
Macho, A.6
-
28
-
-
0038206722
-
Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cellsleads to induction of cell cycle arrest and apoptosis
-
Pham LV, Tamayo AT, Yoshimura LC, Lo P, Ford RJ. Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cellsleads to induction of cell cycle arrest and apoptosis. J Immunol 2003; 171:88-95.
-
(2003)
J Immunol
, vol.171
, pp. 88-95
-
-
Pham, L.V.1
Tamayo, A.T.2
Yoshimura, L.C.3
Lo, P.4
Ford, R.J.5
-
29
-
-
84859164670
-
Immune and non-immune functions of the immunoproteasome
-
Angeles A, Fung G, Luo H. Immune and non-immune functions of the immunoproteasome. Front Biosci 2012;17:1904-16.
-
(2012)
Front Biosci
, vol.17
, pp. 1904-1916
-
-
Angeles, A.1
Fung, G.2
Luo, H.3
-
30
-
-
84857065362
-
Proteasome subtypes and the processing of tumor antigens: Increasing antigenic diversity
-
Vigneron N, Van den Eynde BJ. Proteasome subtypes and the processing of tumor antigens: increasing antigenic diversity. Curr Opin Immunol 2012;24:84-91.
-
(2012)
Curr Opin Immunol
, vol.24
, pp. 84-91
-
-
Vigneron, N.1
Van Den Eynde, B.J.2
-
31
-
-
84862681257
-
The immunoproteasome as a target in hematologic malignancies
-
Kuhn DJ, Orlowski RZ. The immunoproteasome as a target in hematologic malignancies. Semin Hematol 2012;49:258-62.
-
(2012)
Semin Hematol
, vol.49
, pp. 258-262
-
-
Kuhn, D.J.1
Orlowski, R.Z.2
-
32
-
-
83455237998
-
The immunoproteasome: An emerging therapeutic target
-
Lee W, Kim KB. The immunoproteasome: an emerging therapeutic target. Curr Top Med Chem 2011;11:2923-30.
-
(2011)
Curr Top Med Chem
, vol.11
, pp. 2923-2930
-
-
Lee, W.1
Kim, K.B.2
-
33
-
-
33746010219
-
Frequency, characteristics, and reversibility of peripheral neuropathy during treatment of advanced multiple myeloma with bortezomib
-
Richardson PG, Briemberg H, Jagannath S, Wen PY, Barlogie B, Berenson J, et al. Frequency, characteristics, and reversibility of peripheral neuropathy during treatment of advanced multiple myeloma with bortezomib. J Clin Oncol 2006;24:3113-20.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3113-3120
-
-
Richardson, P.G.1
Briemberg, H.2
Jagannath, S.3
Wen, P.Y.4
Barlogie, B.5
Berenson, J.6
-
34
-
-
84867295563
-
A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma
-
Siegel DS, Martin T, Wang M, Vij R, Jakubowiak AJ, Lonial S, et al. A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma. Blood 2012;120: 2817-25.
-
(2012)
Blood
, vol.120
, pp. 2817-2825
-
-
Siegel, D.S.1
Martin, T.2
Wang, M.3
Vij, R.4
Jakubowiak, A.J.5
Lonial, S.6
-
35
-
-
79955498420
-
Nonproteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: A link to clinical adverse events
-
Arastu-Kapur S, Anderl JL, Kraus M, Parlati F, Shenk KD, Lee SJ, et al. Nonproteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: a link to clinical adverse events. Clin Cancer Res 2011;17: 2734-43.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2734-2743
-
-
Arastu-Kapur, S.1
Anderl, J.L.2
Kraus, M.3
Parlati, F.4
Shenk, K.D.5
Lee, S.J.6
-
37
-
-
23044479821
-
Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/Sarrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma
-
Shishodia S, Amin HM, Lai R, Aggarwal BB. Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/Sarrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma. Biochem Pharmacol 2005;70:700-13.
-
(2005)
Biochem Pharmacol
, vol.70
, pp. 700-713
-
-
Shishodia, S.1
Amin, H.M.2
Lai, R.3
Aggarwal, B.B.4
-
38
-
-
0023724778
-
I kappa B: A specific inhibitor of the NFkappa B transcription factor
-
Baeuerle PA, Baltimore D. I kappa B: a specific inhibitor of the NFkappa B transcription factor. Science 1988;242:540-6.
-
(1988)
Science
, vol.242
, pp. 540-546
-
-
Baeuerle, P.A.1
Baltimore, D.2
-
39
-
-
70349243697
-
Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells
-
Hideshima T, Ikeda H, Chauhan D, Okawa Y, Raje N, Podar K, et al. Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells. Blood 2009;114:1046-52.
-
(2009)
Blood
, vol.114
, pp. 1046-1052
-
-
Hideshima, T.1
Ikeda, H.2
Chauhan, D.3
Okawa, Y.4
Raje, N.5
Podar, K.6
-
40
-
-
0032984589
-
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells
-
Catlett-Falcone R, Landowski TH, Oshiro MM, Turkson J, Levitzki A, Savino R, et al. Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunit 1999;10:105-15.
-
(1999)
Immunit
, vol.10
, pp. 105-115
-
-
Catlett-Falcone, R.1
Landowski, T.H.2
Oshiro, M.M.3
Turkson, J.4
Levitzki, A.5
Savino, R.6
-
41
-
-
0033529704
-
Stat3 as an oncogene
-
Bromberg JF, Wrzeszczynska MH, Devgan G, Zhao Y, Pestell RG, Albanese C, et al. Stat3 as an oncogene. Cell 1999;98:295-303.
-
(1999)
Cell
, vol.98
, pp. 295-303
-
-
Bromberg, J.F.1
Wrzeszczynska, M.H.2
Devgan, G.3
Zhao, Y.4
Pestell, R.G.5
Albanese, C.6
-
42
-
-
0037220899
-
Expression of STAT3 and its phosphorylated forms in mantle cell lymphoma cell lines and tumours
-
Lai R, Rassidakis GZ, Medeiros LJ, Leventaki V, Keating M, McDonnell TJ. Expression of STAT3 and its phosphorylated forms in mantle cell lymphoma cell lines and tumours. J Pathol 2003;199: 84-9.
-
(2003)
J Pathol
, vol.199
, pp. 84-89
-
-
Lai, R.1
Rassidakis, G.Z.2
Medeiros, L.J.3
Leventaki, V.4
Keating, M.5
McDonnell, T.J.6
-
43
-
-
23044500732
-
Activation status of the JAK/STAT3 pathway in mantle cell lymphoma
-
Yared MA, Khoury JD, Medeiros LJ, Rassidakis GZ, Lai R. Activation status of the JAK/STAT3 pathway in mantle cell lymphoma. Arch Pathol Lab Med 2005;129:990-6.
-
(2005)
Arch Pathol Lab Med
, vol.129
, pp. 990-996
-
-
Yared, M.A.1
Khoury, J.D.2
Medeiros, L.J.3
Rassidakis, G.Z.4
Lai, R.5
|