Caspase-generated fragment of the Met receptor favors apoptosis via the intrinsic pathway independently of its tyrosine kinase activity

Cell Death and Disease

Volumn 4, Issue 10, 2013, Pages

  Lefebvre, J ^a   Muharram, G ^a   Leroy, C ^a   Kherrouche, Z ^a   Montagne, R ^a   Ichim, G ^b   Tauszig Delamasure, S ^b   Chotteau Lelievre, A ^a   Brenner, C ^c   Mehlen, P ^b   Tulasne, D ^a  

^a UNIV LILLE   (France)

^b UNIVERSITÉ DE LYON   (France)

^c Universite Paris Sud   (France)

Author keywords

Bcl 2 family; C Met; receptor tyrosine kinase; hepatocyte growth factor scatter factor; caspase; apoptosis; dependence receptor; mitochondrial permeabilization

Indexed keywords

CASPASE; CASPASE 3; CYTOCHROME C; PROTEIN BAK; PROTEIN BCL XL; PROTEIN P40; PROTEIN TYROSINE KINASE; SCATTER FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BREAST EPITHELIUM; CELL CULTURE; CELL DEATH; CELL FRACTIONATION; CELL PERMEABILIZATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FULMINANT HEPATIC FAILURE; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; LIVER MITOCHONDRION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; TRANSIENT TRANSFECTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CASPASES; CELL SURVIVAL; CYTOCHROMES C; DOGS; EPITHELIAL CELLS; GENE SILENCING; HUMANS; LIGANDS; MADIN DARBY CANINE KIDNEY CELLS; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA, LIVER; PEPTIDE FRAGMENTS; PERMEABILITY; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-MET; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS;

EID: 84887448046     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.377     Document Type: Article

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