메뉴 건너뛰기




Volumn 65, Issue 12, 2013, Pages 3165-3175

9G4+ autoantibodies are an important source of apoptotic cell reactivity associated with high levels of disease activity in systemic lupus erythematosus

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOTIC CELL ANTIBODYY; AUTOANTIBODY; DOUBLE STRANDED DNA ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN IDIOTYPE; IMMUNOGLOBULIN IDIOTYPE 9G4; IMMUNOGLOBULIN M ANTIBODY; UNCLASSIFIED DRUG;

EID: 84887438320     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.38138     Document Type: Article
Times cited : (22)

References (50)
  • 1
    • 38049123476 scopus 로고    scopus 로고
    • Clearance of apoptotic cells by phagocytes
    • Erwig LP, Henson PM,. Clearance of apoptotic cells by phagocytes. Cell Death Differ 2008; 15: 243-50.
    • (2008) Cell Death Differ , vol.15 , pp. 243-250
    • Erwig, L.P.1    Henson, P.M.2
  • 3
    • 0031838606 scopus 로고    scopus 로고
    • Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus
    • Herrmann M, Voll RE, Zoller OM, Hagenhofer M, Ponner BB, Kalden JR,. Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus. Arthritis Rheum 1998; 41: 1241-50.
    • (1998) Arthritis Rheum , vol.41 , pp. 1241-1250
    • Herrmann, M.1    Voll, R.E.2    Zoller, O.M.3    Hagenhofer, M.4    Ponner, B.B.5    Kalden, J.R.6
  • 4
    • 0036164008 scopus 로고    scopus 로고
    • Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus
    • Baumann I, Kolowos W, Voll RE, Manger B, Gaipl U, Neuhuber WL, et al. Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus. Arthritis Rheum 2002; 46: 191-201.
    • (2002) Arthritis Rheum , vol.46 , pp. 191-201
    • Baumann, I.1    Kolowos, W.2    Voll, R.E.3    Manger, B.4    Gaipl, U.5    Neuhuber, W.L.6
  • 6
    • 0035854442 scopus 로고    scopus 로고
    • Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family
    • Lu Q, Lemke G,. Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family. Science 2001; 293: 306-11.
    • (2001) Science , vol.293 , pp. 306-311
    • Lu, Q.1    Lemke, G.2
  • 8
    • 33947660078 scopus 로고    scopus 로고
    • Glomerular apoptotic nucleosomes are central target structures for nephritogenic antibodies in human SLE nephritis
    • Kalaaji M, Fenton KA, Mortensen ES, Olsen R, Sturfelt G, Alm P, et al. Glomerular apoptotic nucleosomes are central target structures for nephritogenic antibodies in human SLE nephritis. Kidney Int 2007; 71: 664-72.
    • (2007) Kidney Int , vol.71 , pp. 664-672
    • Kalaaji, M.1    Fenton, K.A.2    Mortensen, E.S.3    Olsen, R.4    Sturfelt, G.5    Alm, P.6
  • 10
    • 54349096879 scopus 로고    scopus 로고
    • IgG autoantibodies bound to surfaces of necrotic cells and complement C4 comprise the phagocytosis promoting activity for necrotic cells of systemic lupus erythaematosus sera
    • Grossmayer GE, Munoz LE, Weber CK, Franz S, Voll RE, Kern PM, et al. IgG autoantibodies bound to surfaces of necrotic cells and complement C4 comprise the phagocytosis promoting activity for necrotic cells of systemic lupus erythaematosus sera. Ann Rheum Dis 2008; 67: 1626-32.
    • (2008) Ann Rheum Dis , vol.67 , pp. 1626-1632
    • Grossmayer, G.E.1    Munoz, L.E.2    Weber, C.K.3    Franz, S.4    Voll, R.E.5    Kern, P.M.6
  • 11
    • 0035421308 scopus 로고    scopus 로고
    • Activation of natural interferon-α producing cells by apoptotic U937 cells combined with lupus IgG and its regulation by cytokines
    • Bave U, Vallin H, Alm GV, Ronnblom L,. Activation of natural interferon-α producing cells by apoptotic U937 cells combined with lupus IgG and its regulation by cytokines. J Autoimmun 2001; 17: 71-80.
    • (2001) J Autoimmun , vol.17 , pp. 71-80
    • Bave, U.1    Vallin, H.2    Alm, G.V.3    Ronnblom, L.4
  • 12
    • 66449089455 scopus 로고    scopus 로고
    • Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus
    • Munoz LE, Janko C, Grossmayer GE, Frey B, Voll RE, Kern P, et al. Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus. Arthritis Rheum 2009; 60: 1733-42.
    • (2009) Arthritis Rheum , vol.60 , pp. 1733-1742
    • Munoz, L.E.1    Janko, C.2    Grossmayer, G.E.3    Frey, B.4    Voll, R.E.5    Kern, P.6
  • 13
    • 84856022097 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells and C1q differentially regulate inflammatory gene induction by lupus immune complexes
    • Santer DM, Wiedeman AE, Teal TH, Ghosh P, Elkon KB,. Plasmacytoid dendritic cells and C1q differentially regulate inflammatory gene induction by lupus immune complexes. J Immunol 2012; 188: 902-15.
    • (2012) J Immunol , vol.188 , pp. 902-915
    • Santer, D.M.1    Wiedeman, A.E.2    Teal, T.H.3    Ghosh, P.4    Elkon, K.B.5
  • 14
    • 35348836191 scopus 로고    scopus 로고
    • Opsonization of late apoptotic cells by systemic lupus erythematosus autoantibodies inhibits their uptake via an Fcγ receptor-dependent mechanism
    • Reefman E, Horst G, Nijk MT, Limburg PC, Kallenberg CG, Bijl M,. Opsonization of late apoptotic cells by systemic lupus erythematosus autoantibodies inhibits their uptake via an Fcγ receptor-dependent mechanism. Arthritis Rheum 2007; 56: 3399-411.
    • (2007) Arthritis Rheum , vol.56 , pp. 3399-3411
    • Reefman, E.1    Horst, G.2    Nijk, M.T.3    Limburg, P.C.4    Kallenberg, C.G.5    Bijl, M.6
  • 15
    • 84857362706 scopus 로고    scopus 로고
    • IgM autoantibodies to distinct apoptosis-associated antigens correlate with protection from cardiovascular events and renal disease in patients with SLE
    • Gronwall C, Akhter E, Oh C, Burlingame RW, Petri M, Silverman GJ,. IgM autoantibodies to distinct apoptosis-associated antigens correlate with protection from cardiovascular events and renal disease in patients with SLE. Clin Immunol 2012; 142: 390-8.
    • (2012) Clin Immunol , vol.142 , pp. 390-398
    • Gronwall, C.1    Akhter, E.2    Oh, C.3    Burlingame, R.W.4    Petri, M.5    Silverman, G.J.6
  • 16
    • 1642355937 scopus 로고    scopus 로고
    • Lupus IgG VH4.34 antibodies bind to a 220-kDa glycoform of CD45/B220 on the surface of human B lymphocytes
    • Cappione AJ, Pugh-Bernard AE, Anolik JH, Sanz I,. Lupus IgG VH4.34 antibodies bind to a 220-kDa glycoform of CD45/B220 on the surface of human B lymphocytes. J Immunol 2004; 172: 4298-307.
    • (2004) J Immunol , vol.172 , pp. 4298-4307
    • Cappione, A.J.1    Pugh-Bernard, A.E.2    Anolik, J.H.3    Sanz, I.4
  • 17
    • 27644452293 scopus 로고    scopus 로고
    • Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus
    • Cappione A III, Anolik JH, Pugh-Bernard A, Barnard J, Dutcher P, Silverman G, et al. Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus. J Clin Invest 2005; 115: 3205-16.
    • (2005) J Clin Invest , vol.115 , pp. 3205-3216
    • Cappione III, A.1    Anolik, J.H.2    Pugh-Bernard, A.3    Barnard, J.4    Dutcher, P.5    Silverman, G.6
  • 20
    • 0032812236 scopus 로고    scopus 로고
    • VH4-34 encoded antibodies in systemic lupus erythematosus: A specific diagnostic marker that correlates with clinical disease characteristics
    • Van Vollenhoven RF, Bieber MM, Powell MJ, Gupta PK, Bhat NM, Richards KL, et al. VH4-34 encoded antibodies in systemic lupus erythematosus: a specific diagnostic marker that correlates with clinical disease characteristics. J Rheumatol 1999; 26: 1727-33.
    • (1999) J Rheumatol , vol.26 , pp. 1727-1733
    • Van Vollenhoven, R.F.1    Bieber, M.M.2    Powell, M.J.3    Gupta, P.K.4    Bhat, N.M.5    Richards, K.L.6
  • 23
    • 0026777352 scopus 로고
    • Derivation of the SLEDAI: A disease activity index for lupus patients
    • the Committee on Prognosis Studies in SLE
    • Bombardier C, Gladman DD, Urowitz MB, Caron D, Chang DH, and the Committee on Prognosis Studies in SLE. Derivation of the SLEDAI: a disease activity index for lupus patients. Arthritis Rheum 1992; 35: 630-40.
    • (1992) Arthritis Rheum , vol.35 , pp. 630-640
    • Bombardier, C.1    Gladman, D.D.2    Urowitz, M.B.3    Caron, D.4    Chang, D.H.5
  • 24
    • 47349112642 scopus 로고    scopus 로고
    • Quantitative image based apoptotic index measurement using multispectral imaging flow cytometry: A comparison with standard photometric methods
    • Henery S, George T, Hall B, Basiji D, Ortyn W, Morrissey P,. Quantitative image based apoptotic index measurement using multispectral imaging flow cytometry: a comparison with standard photometric methods. Apoptosis 2008; 13: 1054-63.
    • (2008) Apoptosis , vol.13 , pp. 1054-1063
    • Henery, S.1    George, T.2    Hall, B.3    Basiji, D.4    Ortyn, W.5    Morrissey, P.6
  • 25
    • 36849031722 scopus 로고    scopus 로고
    • Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning
    • [published erratum appears in J Immunol Methods 2008;334:142]
    • Tiller T, Meffre E, Yurasov S, Tsuiji M, Nussenzweig MC, Wardemann H,. Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning [published erratum appears in J Immunol Methods 2008;334:142]. J Immunol Methods 2008; 329: 112-24.
    • (2008) J Immunol Methods , vol.329 , pp. 112-124
    • Tiller, T.1    Meffre, E.2    Yurasov, S.3    Tsuiji, M.4    Nussenzweig, M.C.5    Wardemann, H.6
  • 29
    • 55749114077 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia cells recognize conserved epitopes associated with apoptosis and oxidation
    • Catera R, Silverman GJ, Hatzi K, Seiler T, Didier S, Zhang L, et al. Chronic lymphocytic leukemia cells recognize conserved epitopes associated with apoptosis and oxidation. Mol Med 2008; 14: 665-74.
    • (2008) Mol Med , vol.14 , pp. 665-674
    • Catera, R.1    Silverman, G.J.2    Hatzi, K.3    Seiler, T.4    Didier, S.5    Zhang, L.6
  • 30
    • 0030221691 scopus 로고    scopus 로고
    • The V4-34 encoded anti-i autoantibodies recognize a large subset of human and mouse B-cells
    • Silberstein LE, George A, Durdik JM, Kipps TJ,. The V4-34 encoded anti-i autoantibodies recognize a large subset of human and mouse B-cells. Blood Cells Mol Dis 1996; 22: 126-38.
    • (1996) Blood Cells Mol Dis , vol.22 , pp. 126-138
    • Silberstein, L.E.1    George, A.2    Durdik, J.M.3    Kipps, T.J.4
  • 31
    • 84863193350 scopus 로고    scopus 로고
    • Prevalence and sociodemographic correlates of antinuclear antibodies in the United States
    • Satoh M, Chan EK, Ho LA, Rose KM, Parks CG, Cohn RD, et al. Prevalence and sociodemographic correlates of antinuclear antibodies in the United States. Arthritis Rheum 2012; 64: 2319-27.
    • (2012) Arthritis Rheum , vol.64 , pp. 2319-2327
    • Satoh, M.1    Chan, E.K.2    Ho, L.A.3    Rose, K.M.4    Parks, C.G.5    Cohn, R.D.6
  • 32
    • 33645084540 scopus 로고    scopus 로고
    • Correlations between antinucleosome antibodies and anti-double-stranded DNA antibodies, C3, C4, and clinical activity in lupus patients
    • Saisoong S, Eiam-Ong S, Hanvivatvong O,. Correlations between antinucleosome antibodies and anti-double-stranded DNA antibodies, C3, C4, and clinical activity in lupus patients. Clin Exp Rheumatol 2006; 24: 51-8.
    • (2006) Clin Exp Rheumatol , vol.24 , pp. 51-58
    • Saisoong, S.1    Eiam-Ong, S.2    Hanvivatvong, O.3
  • 34
    • 29644434294 scopus 로고    scopus 로고
    • Heterogeneous nuclear ribonucleoprotein P2 is an autoantibody target in mice deficient for Mer, Axl, and Tyro3 receptor tyrosine kinases
    • Radic MZ, Shah K, Zhang W, Lu Q, Lemke G, Hilliard GM,. Heterogeneous nuclear ribonucleoprotein P2 is an autoantibody target in mice deficient for Mer, Axl, and Tyro3 receptor tyrosine kinases. J Immunol 2006; 176: 68-74.
    • (2006) J Immunol , vol.176 , pp. 68-74
    • Radic, M.Z.1    Shah, K.2    Zhang, W.3    Lu, Q.4    Lemke, G.5    Hilliard, G.M.6
  • 35
    • 3042753858 scopus 로고    scopus 로고
    • Apoptosis, subcellular particles, and autoimmunity
    • Cline AM, Radic MZ,. Apoptosis, subcellular particles, and autoimmunity. Clin Immunol 2004; 112: 175-82.
    • (2004) Clin Immunol , vol.112 , pp. 175-182
    • Cline, A.M.1    Radic, M.Z.2
  • 36
    • 0028288510 scopus 로고
    • Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes
    • Casciola-Rosen LA, Anhalt G, Rosen A,. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J Exp Med 1994; 179: 1317-30.
    • (1994) J Exp Med , vol.179 , pp. 1317-1330
    • Casciola-Rosen, L.A.1    Anhalt, G.2    Rosen, A.3
  • 37
    • 37849186218 scopus 로고    scopus 로고
    • Divergent members of a single autoreactive B cell clone retain specificity for apoptotic blebs
    • Neeli I, Richardson MM, Khan SN, Nicolo D, Monestier M, Radic MZ,. Divergent members of a single autoreactive B cell clone retain specificity for apoptotic blebs. Mol Immunol 2007; 44: 1914-21.
    • (2007) Mol Immunol , vol.44 , pp. 1914-1921
    • Neeli, I.1    Richardson, M.M.2    Khan, S.N.3    Nicolo, D.4    Monestier, M.5    Radic, M.Z.6
  • 38
    • 59749086598 scopus 로고    scopus 로고
    • Endogenous humoral autoreactive immune responses to apoptotic cells: Effects on phagocytic uptake, chemotactic migration and antigenic spread
    • Das J, Arora P, Gracias D, Praveen A, Raj BP, Martin E, et al. Endogenous humoral autoreactive immune responses to apoptotic cells: effects on phagocytic uptake, chemotactic migration and antigenic spread. Eur J Immunol 2008; 38: 3561-74.
    • (2008) Eur J Immunol , vol.38 , pp. 3561-3574
    • Das, J.1    Arora, P.2    Gracias, D.3    Praveen, A.4    Raj, B.P.5    Martin, E.6
  • 39
    • 59649126956 scopus 로고    scopus 로고
    • Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: Implications for the pathogenesis of SLE
    • Urbonaviciute V, Furnrohr BG, Meister S, Munoz L, Heyder P, De Marchis F, et al. Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE. J Exp Med 2008; 205: 3007-18.
    • (2008) J Exp Med , vol.205 , pp. 3007-3018
    • Urbonaviciute, V.1    Furnrohr, B.G.2    Meister, S.3    Munoz, L.4    Heyder, P.5    De Marchis, F.6
  • 40
    • 0034726716 scopus 로고    scopus 로고
    • Naturally occurring anti-band 3 antibody binds to apoptotic human T-lymphoid cell line Jurkat through sialylated poly-N-acetyllactosaminyl saccharide chains on the cell surface
    • Ando K, Hagiwara T, Beppu M, Kikugawa K,. Naturally occurring anti-band 3 antibody binds to apoptotic human T-lymphoid cell line Jurkat through sialylated poly-N-acetyllactosaminyl saccharide chains on the cell surface. Biochem Biophys Res Commun 2000; 275: 412-7.
    • (2000) Biochem Biophys Res Commun , vol.275 , pp. 412-417
    • Ando, K.1    Hagiwara, T.2    Beppu, M.3    Kikugawa, K.4
  • 41
    • 1242294401 scopus 로고    scopus 로고
    • Carbohydrate-mediated phagocytic recognition of early apoptotic cells undergoing transient capping of CD43 glycoprotein
    • Eda S, Yamanaka M, Beppu M,. Carbohydrate-mediated phagocytic recognition of early apoptotic cells undergoing transient capping of CD43 glycoprotein. J Biol Chem 2004; 279: 5967-74.
    • (2004) J Biol Chem , vol.279 , pp. 5967-5974
    • Eda, S.1    Yamanaka, M.2    Beppu, M.3
  • 42
    • 0036143018 scopus 로고    scopus 로고
    • Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation
    • Huynh ML, Fadok VA, Henson PM,. Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation. J Clin Invest 2002; 109: 41-50.
    • (2002) J Clin Invest , vol.109 , pp. 41-50
    • Huynh, M.L.1    Fadok, V.A.2    Henson, P.M.3
  • 43
    • 79952646821 scopus 로고    scopus 로고
    • Abnormal production of pro- and anti-inflammatory cytokines by lupus monocytes in response to apoptotic cells
    • Sule S, Rosen A, Petri M, Akhter E, Andrade F,. Abnormal production of pro- and anti-inflammatory cytokines by lupus monocytes in response to apoptotic cells. PLoS One 2011; 6: e17495.
    • (2011) PLoS One , vol.6
    • Sule, S.1    Rosen, A.2    Petri, M.3    Akhter, E.4    Andrade, F.5
  • 44
    • 23444461619 scopus 로고    scopus 로고
    • Nuclear autoantigen translocation and autoantibody opsonization lead to increased dendritic cell phagocytosis and presentation of nuclear antigens: A novel pathogenic pathway for autoimmunity?
    • Frisoni L, McPhie L, Colonna L, Sriram U, Monestier M, Gallucci S, et al. Nuclear autoantigen translocation and autoantibody opsonization lead to increased dendritic cell phagocytosis and presentation of nuclear antigens: a novel pathogenic pathway for autoimmunity? J Immunol 2005; 175: 2692-701.
    • (2005) J Immunol , vol.175 , pp. 2692-2701
    • Frisoni, L.1    McPhie, L.2    Colonna, L.3    Sriram, U.4    Monestier, M.5    Gallucci, S.6
  • 46
    • 0037903481 scopus 로고    scopus 로고
    • Major peptide autoepitopes for nucleosome-centered T and B cell interaction in human and murine lupus
    • Datta SK,. Major peptide autoepitopes for nucleosome-centered T and B cell interaction in human and murine lupus. Ann N Y Acad Sci 2003; 987: 79-90.
    • (2003) Ann N y Acad Sci , vol.987 , pp. 79-90
    • Datta, S.K.1
  • 47
    • 0032917731 scopus 로고    scopus 로고
    • Autoantigens as substrates for apoptotic proteases: Implications for the pathogenesis of systemic autoimmune disease
    • Rosen A, Casciola-Rosen L,. Autoantigens as substrates for apoptotic proteases: implications for the pathogenesis of systemic autoimmune disease. Cell Death Differ 1999; 6: 6-12.
    • (1999) Cell Death Differ , vol.6 , pp. 6-12
    • Rosen, A.1    Casciola-Rosen, L.2
  • 48
    • 9444254707 scopus 로고    scopus 로고
    • Rearrangement of nuclear ribonucleoprotein (RNP)-containing structures during apoptosis and transcriptional arrest
    • Biggiogera M, Bottone MG, Scovassi AI, Soldani C, Vecchio L, Pellicciari C,. Rearrangement of nuclear ribonucleoprotein (RNP)-containing structures during apoptosis and transcriptional arrest. Biol Cell 2004; 96: 603-15.
    • (2004) Biol Cell , vol.96 , pp. 603-615
    • Biggiogera, M.1    Bottone, M.G.2    Scovassi, A.I.3    Soldani, C.4    Vecchio, L.5    Pellicciari, C.6
  • 49
    • 0029979577 scopus 로고    scopus 로고
    • The i binding specificity of human VH 4-34 (VH 4-21) encoded antibodies is determined by both VH framework region 1 and complementarity determining region 3
    • Li Y, Spellerberg MB, Stevenson FK, Capra JD, Potter KN,. The I binding specificity of human VH 4-34 (VH 4-21) encoded antibodies is determined by both VH framework region 1 and complementarity determining region 3. J Mol Biol 1996; 256: 577-89.
    • (1996) J Mol Biol , vol.256 , pp. 577-589
    • Li, Y.1    Spellerberg, M.B.2    Stevenson, F.K.3    Capra, J.D.4    Potter, K.N.5
  • 50
    • 84860008585 scopus 로고    scopus 로고
    • 9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activity
    • Kobie JJ, Alcena DC, Zheng B, Bryk P, Mattiacio JL, Brewer M, et al. 9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activity. PLoS One 2012; 7: e35356.
    • (2012) PLoS One , vol.7
    • Kobie, J.J.1    Alcena, D.C.2    Zheng, B.3    Bryk, P.4    Mattiacio, J.L.5    Brewer, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.