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Volumn 21, Issue 11, 2013, Pages 2122-2129

Persistence and efficacy of second generation CAR T Cell against the LeY Antigen in acute myeloid leukemia

Author keywords

[No Author keywords available]

Indexed keywords

CYTARABINE; FLUDARABINE; GAMMA INTERFERON; GEMTUZUMAB OZOGAMICIN; IDARUBICIN; INDIUM 111; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; TUMOR NECROSIS FACTOR;

EID: 84887419384     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2013.154     Document Type: Article
Times cited : (361)

References (39)
  • 1
    • 79952129510 scopus 로고    scopus 로고
    • Allogeneic hematopoietic cell transplantation for adults with acute myeloid leukemia: Myths, controversies, and unknowns
    • Gupta, V, Tallman, MS and Weisdorf, DJ (2011). Allogeneic hematopoietic cell transplantation for adults with acute myeloid leukemia: myths, controversies, and unknowns. Blood 117: 2307-2318.
    • (2011) Blood , vol.117 , pp. 2307-2318
    • Gupta, V.1    Tallman, M.S.2    Weisdorf, D.J.3
  • 2
    • 33750699642 scopus 로고    scopus 로고
    • A phase i study on adoptive immunotherapy using gene-modified T cells for ovarian cancer
    • Kershaw, MH, Westwood, JA, Parker, LL, Wang, G, Eshhar, Z, Mavroukakis, SA et al. (2006). A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer. Clin Cancer Res 12(20 Pt 1): 6106-6115.
    • (2006) Clin Cancer Res , vol.12 , Issue.20 PART 1 , pp. 6106-6115
    • Kershaw, M.H.1    Westwood, J.A.2    Parker, L.L.3    Wang, G.4    Eshhar, Z.5    Mavroukakis, S.A.6
  • 3
    • 0035869383 scopus 로고    scopus 로고
    • Idiotype-specific cytotoxic T lymphocytes in multiple myeloma: Evidence for their capacity to lyse autologous primary tumor cells
    • Wen, YJ, Barlogie, B and Yi, Q (2001). Idiotype-specific cytotoxic T lymphocytes in multiple myeloma: evidence for their capacity to lyse autologous primary tumor cells. Blood 97: 1750-1755.
    • (2001) Blood , vol.97 , pp. 1750-1755
    • Wen, Y.J.1    Barlogie, B.2    Yi, Q.3
  • 4
    • 0036565872 scopus 로고    scopus 로고
    • Tumor lysate-specific cytotoxic T lymphocytes in multiple myeloma: Promising effector cells for immunotherapy
    • Wen, YJ, Min, R, Tricot, G, Barlogie, B and Yi, Q (2002). Tumor lysate-specific cytotoxic T lymphocytes in multiple myeloma: promising effector cells for immunotherapy. Blood 99: 3280-3285.
    • (2002) Blood , vol.99 , pp. 3280-3285
    • Wen, Y.J.1    Min, R.2    Tricot, G.3    Barlogie, B.4    Yi, Q.5
  • 5
    • 0034693937 scopus 로고    scopus 로고
    • Expansion and characterization of T cells transduced with a chimeric receptor against ovarian cancer
    • Parker, LL, Do, MT, Westwood, JA, Wunderlich, JR, Dudley, ME, Rosenberg, SA et al. (2000). Expansion and characterization of T cells transduced with a chimeric receptor against ovarian cancer. Hum Gene Ther 11: 2377-2387.
    • (2000) Hum Gene Ther , vol.11 , pp. 2377-2387
    • Parker, L.L.1    Do, M.T.2    Westwood, J.A.3    Wunderlich, J.R.4    Dudley, M.E.5    Rosenberg, S.A.6
  • 6
    • 33646398347 scopus 로고    scopus 로고
    • Manufacturing of gene-modified cytotoxic T lymphocytes for autologous cellular therapy for lymphoma
    • Cooper, LJ, Ausubel, L, Gutierrez, M, Stephan, S, Shakeley, R, Olivares, S et al. (2006). Manufacturing of gene-modified cytotoxic T lymphocytes for autologous cellular therapy for lymphoma. Cytotherapy 8: 105-117.
    • (2006) Cytotherapy , vol.8 , pp. 105-117
    • Cooper, L.J.1    Ausubel, L.2    Gutierrez, M.3    Stephan, S.4    Shakeley, R.5    Olivares, S.6
  • 7
    • 0036019378 scopus 로고    scopus 로고
    • Protocol for gene transduction and expansion of human T lymphocytes for clinical immunogene therapy of cancer
    • Lamers, CH, Willemsen, RA, Luider, BA, Debets, R and Bolhuis, RL (2002). Protocol for gene transduction and expansion of human T lymphocytes for clinical immunogene therapy of cancer. Cancer Gene Ther 9: 613-623.
    • (2002) Cancer Gene Ther , vol.9 , pp. 613-623
    • Lamers, C.H.1    Willemsen, R.A.2    Luider, B.A.3    Debets, R.4    Bolhuis, R.L.5
  • 8
    • 0027501259 scopus 로고
    • Targeting of T lymphocytes to Neu/HER2-expressing cells using chimeric single chain Fv receptors
    • Stancovski, I, Schindler, DG, Waks, T, Yarden, Y, Sela, M and Eshhar, Z (1993). Targeting of T lymphocytes to Neu/HER2-expressing cells using chimeric single chain Fv receptors. J Immunol 151: 6577-6582.
    • (1993) J Immunol , vol.151 , pp. 6577-6582
    • Stancovski, I.1    Schindler, D.G.2    Waks, T.3    Yarden, Y.4    Sela, M.5    Eshhar, Z.6
  • 9
    • 0027283443 scopus 로고
    • Lysis of ovarian cancer cells by human lymphocytes redirected with a chimeric gene composed of an antibody variable region and the Fc receptor gamma chain
    • Hwu, P, Shafer, GE, Treisman, J, Schindler, DG, Gross, G, Cowherd, R et al. (1993). Lysis of ovarian cancer cells by human lymphocytes redirected with a chimeric gene composed of an antibody variable region and the Fc receptor gamma chain. J Exp Med 178: 361-366.
    • (1993) J Exp Med , vol.178 , pp. 361-366
    • Hwu, P.1    Shafer, G.E.2    Treisman, J.3    Schindler, D.G.4    Gross, G.5    Cowherd, R.6
  • 10
    • 0037264471 scopus 로고    scopus 로고
    • Targeting tumours with genetically enhanced T lymphocytes
    • Sadelain, M, Rivière, I and Brentjens, R (2003). Targeting tumours with genetically enhanced T lymphocytes. Nat Rev Cancer 3: 35-45.
    • (2003) Nat Rev Cancer , vol.3 , pp. 35-45
    • Sadelain, M.1    Rivière, I.2    Brentjens, R.3
  • 11
    • 0036905078 scopus 로고    scopus 로고
    • Dual-specific T cells combine proliferation and antitumor activity
    • Kershaw, MH, Westwood, JA and Hwu, P (2002). Dual-specific T cells combine proliferation and antitumor activity. Nat Biotechnol 20: 1221-1227.
    • (2002) Nat Biotechnol , vol.20 , pp. 1221-1227
    • Kershaw, M.H.1    Westwood, J.A.2    Hwu, P.3
  • 12
    • 0028328257 scopus 로고
    • Cytotoxic T lymphocytes with a grafted recognition specificity for ERBB2-expressing tumor cells
    • Moritz, D, Wels, W, Mattern, J and Groner, B (1994). Cytotoxic T lymphocytes with a grafted recognition specificity for ERBB2-expressing tumor cells. Proc Natl Acad Sci USA 91: 4318-4322.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4318-4322
    • Moritz, D.1    Wels, W.2    Mattern, J.3    Groner, B.4
  • 13
    • 0027471898 scopus 로고
    • Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors
    • Eshhar, Z, Waks, T, Gross, G and Schindler, DG (1993). Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors. Proc Natl Acad Sci USA 90: 720-724.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 720-724
    • Eshhar, Z.1    Waks, T.2    Gross, G.3    Schindler, D.G.4
  • 14
    • 0036839589 scopus 로고    scopus 로고
    • Single-chain antigen recognition receptors that costimulate potent rejection of established experimental tumors
    • Haynes, NM, Trapani, JA, Teng, MW, Jackson, JT, Cerruti, L, Jane, SM et al. (2002). Single-chain antigen recognition receptors that costimulate potent rejection of established experimental tumors. Blood 100: 3155-3163.
    • (2002) Blood , vol.100 , pp. 3155-3163
    • Haynes, N.M.1    Trapani, J.A.2    Teng, M.W.3    Jackson, J.T.4    Cerruti, L.5    Jane, S.M.6
  • 15
    • 0036137615 scopus 로고    scopus 로고
    • Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRzeta/CD28 receptor
    • Maher, J, Brentjens, RJ, Gunset, G, Rivière, I and Sadelain, M (2002). Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRzeta/CD28 receptor. Nat Biotechnol 20: 70-75.
    • (2002) Nat Biotechnol , vol.20 , pp. 70-75
    • Maher, J.1    Brentjens, R.J.2    Gunset, G.3    Rivière, I.4    Sadelain, M.5
  • 16
    • 27744566329 scopus 로고    scopus 로고
    • A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells
    • Pulè, MA, Straathof, KC, Dotti, G, Heslop, HE, Rooney, CM and Brenner, MK (2005). A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells. Mol Ther 12: 933-941.
    • (2005) Mol Ther , vol.12 , pp. 933-941
    • Pulè, M.A.1    Straathof, K.C.2    Dotti, G.3    Heslop, H.E.4    Rooney, C.M.5    Brenner, M.K.6
  • 17
    • 84863337890 scopus 로고    scopus 로고
    • B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
    • Kochenderfer, JN, Dudley, ME, Feldman, SA, Wilson, WH, Spaner, DE, Maric, I et al. (2012). B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood 119: 2709-2720.
    • (2012) Blood , vol.119 , pp. 2709-2720
    • Kochenderfer, J.N.1    Dudley, M.E.2    Feldman, S.A.3    Wilson, W.H.4    Spaner, D.E.5    Maric, I.6
  • 18
    • 80051720194 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
    • Porter, DL, Levine, BL, Kalos, M, Bagg, A and June, CH (2011). Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N Engl J Med 365: 725-733.
    • (2011) N Engl J Med , vol.365 , pp. 725-733
    • Porter, D.L.1    Levine, B.L.2    Kalos, M.3    Bagg, A.4    June, C.H.5
  • 19
    • 0029931120 scopus 로고    scopus 로고
    • Serological and immunochemical analysis of Lewis y (Ley) blood group antigen expression in epithelial ovarian cancer
    • Yin, BW, Finstad, CL, Kitamura, K, Federici, MG, Welshinger, M, Kudryashov, V et al. (1996). Serological and immunochemical analysis of Lewis y (Ley) blood group antigen expression in epithelial ovarian cancer. Int J Cancer 65: 406-412.
    • (1996) Int J Cancer , vol.65 , pp. 406-412
    • Yin, B.W.1    Finstad, C.L.2    Kitamura, K.3    Federici, M.G.4    Welshinger, M.5    Kudryashov, V.6
  • 20
    • 0030765682 scopus 로고    scopus 로고
    • Selection of tumor antigens as targets for immune attack using immunohistochemistry: II. Blood group-related antigens
    • Zhang, S, Zhang, HS, Cordon-Cardo, C, Reuter, VE, Singhal, AK, Lloyd, KO et al. (1997). Selection of tumor antigens as targets for immune attack using immunohistochemistry: II. Blood group-related antigens. Int J Cancer 73: 50-56.
    • (1997) Int J Cancer , vol.73 , pp. 50-56
    • Zhang, S.1    Zhang, H.S.2    Cordon-Cardo, C.3    Reuter, V.E.4    Singhal, A.K.5    Lloyd, K.O.6
  • 21
    • 0022559251 scopus 로고
    • Expression of Lewisa, Lewisb, X, and y blood group antigens in human colonic tumors and normal tissue and in human tumor-derived cell lines
    • Sakamoto, J, Furukawa, K, Cordon-Cardo, C, Yin, BW, Rettig, WJ, Oettgen, HF et al. (1986). Expression of Lewisa, Lewisb, X, and Y blood group antigens in human colonic tumors and normal tissue and in human tumor-derived cell lines. Cancer Res 46: 1553-1561.
    • (1986) Cancer Res , vol.46 , pp. 1553-1561
    • Sakamoto, J.1    Furukawa, K.2    Cordon-Cardo, C.3    Yin, B.W.4    Rettig, W.J.5    Oettgen, H.F.6
  • 22
    • 0027271902 scopus 로고
    • Lewis blood group-related antigen expression in normal gastric epithelium, intestinal metaplasia, gastric adenoma, and gastric carcinoma
    • Kobayashi, K, Sakamoto, J, Kito, T, Yamamura, Y, Koshikawa, T, Fujita, M et al. (1993). Lewis blood group-related antigen expression in normal gastric epithelium, intestinal metaplasia, gastric adenoma, and gastric carcinoma. Am J Gastroenterol 88: 919-924.
    • (1993) Am J Gastroenterol , vol.88 , pp. 919-924
    • Kobayashi, K.1    Sakamoto, J.2    Kito, T.3    Yamamura, Y.4    Koshikawa, T.5    Fujita, M.6
  • 23
    • 0026734888 scopus 로고
    • Correlation of expression of H/Le(y)/Le(b) antigens with survival in patients with carcinoma of the lung
    • Miyake, M, Taki, T, Hitomi, S and Hakomori, S (1992). Correlation of expression of H/Le(y)/Le(b) antigens with survival in patients with carcinoma of the lung. N Engl J Med 327: 14-18.
    • (1992) N Engl J Med , vol.327 , pp. 14-18
    • Miyake, M.1    Taki, T.2    Hitomi, S.3    Hakomori, S.4
  • 24
    • 30044442768 scopus 로고    scopus 로고
    • Adoptive transfer of T cells modified with a humanized chimeric receptor gene inhibits growth of Lewis-Y-expressing tumors in mice
    • Westwood, JA, Smyth, MJ, Teng, MW, Moeller, M, Trapani, JA, Scott, AM et al. (2005). Adoptive transfer of T cells modified with a humanized chimeric receptor gene inhibits growth of Lewis-Y-expressing tumors in mice. Proc Natl Acad Sci USA 102: 19051-19056.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 19051-19056
    • Westwood, J.A.1    Smyth, M.J.2    Teng, M.W.3    Moeller, M.4    Trapani, J.A.5    Scott, A.M.6
  • 25
    • 77956617361 scopus 로고    scopus 로고
    • Ex vivo culture of chimeric antigen receptor T cells generates functional CD8+ T cells with effector and central memory-like phenotype
    • Neeson, P, Shin, A, Tainton, KM, Guru, P, Prince, HM, Harrison, SJ et al. (2010). Ex vivo culture of chimeric antigen receptor T cells generates functional CD8+ T cells with effector and central memory-like phenotype. Gene Ther 17: 1105-1116.
    • (2010) Gene Ther , vol.17 , pp. 1105-1116
    • Neeson, P.1    Shin, A.2    Tainton, K.M.3    Guru, P.4    Prince, H.M.5    Harrison, S.J.6
  • 26
    • 77952420345 scopus 로고    scopus 로고
    • Gene-modified T cells as immunotherapy for multiple myeloma and acute myeloid leukemia expressing the Lewis y antigen
    • Peinert, S, Prince, HM, Guru, PM, Kershaw, MH, Smyth, MJ, Trapani, JA et al. (2010). Gene-modified T cells as immunotherapy for multiple myeloma and acute myeloid leukemia expressing the Lewis Y antigen. Gene Ther 17: 678-686.
    • (2010) Gene Ther , vol.17 , pp. 678-686
    • Peinert, S.1    Prince, H.M.2    Guru, P.M.3    Kershaw, M.H.4    Smyth, M.J.5    Trapani, J.A.6
  • 27
    • 80455179612 scopus 로고    scopus 로고
    • Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias
    • Brentjens, RJ, Rivière, I, Park, JH, Davila, ML, Wang, X, Stefanski, J et al. (2011). Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias. Blood 118: 4817-4828.
    • (2011) Blood , vol.118 , pp. 4817-4828
    • Brentjens, R.J.1    Rivière, I.2    Park, J.H.3    Davila, M.L.4    Wang, X.5    Stefanski, J.6
  • 28
    • 84860333968 scopus 로고    scopus 로고
    • CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: Pilot clinical trial results
    • Till, BG, Jensen, MC, Wang, J, Qian, X, Gopal, AK, Maloney, DG et al. (2012). CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: pilot clinical trial results. Blood 119: 3940-3950.
    • (2012) Blood , vol.119 , pp. 3940-3950
    • Till, B.G.1    Jensen, M.C.2    Wang, J.3    Qian, X.4    Gopal, A.K.5    Maloney, D.G.6
  • 29
    • 84861122295 scopus 로고    scopus 로고
    • The future is now: Chimeric antigen receptors as new targeted therapies for childhood cancer
    • Lee, DW, Barrett, DM, Mackall, C, Orentas, R and Grupp, SA (2012). The future is now: chimeric antigen receptors as new targeted therapies for childhood cancer. Clin Cancer Res 18: 2780-2790.
    • (2012) Clin Cancer Res , vol.18 , pp. 2780-2790
    • Lee, D.W.1    Barrett, D.M.2    MacKall, C.3    Orentas, R.4    Grupp, S.A.5
  • 30
    • 80051775476 scopus 로고    scopus 로고
    • T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
    • Kalos, M, Levine, BL, Porter, DL, Katz, S, Grupp, SA, Bagg, A et al. (2011). T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci Transl Med 3: 95ra73.
    • (2011) Sci Transl Med , vol.3
    • Kalos, M.1    Levine, B.L.2    Porter, D.L.3    Katz, S.4    Grupp, S.A.5    Bagg, A.6
  • 31
    • 77950475517 scopus 로고    scopus 로고
    • Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
    • Morgan, RA, Yang, JC, Kitano, M, Dudley, ME, Laurencot, CM, and Rosenberg, SA (2010). Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol Ther 18: 843-851.
    • (2010) Mol Ther , vol.18 , pp. 843-851
    • Morgan, R.A.1    Yang, J.C.2    Kitano, M.3    Dudley, M.E.4    Laurencot, C.M.5    Rosenberg, S.A.6
  • 32
    • 70449486486 scopus 로고    scopus 로고
    • Lack of specific gamma-retroviral vector long terminal repeat promoter silencing in patients receiving genetically engineered lymphocytes and activation upon lymphocyte restimulation
    • Burns, WR, Zheng, Z, Rosenberg, SA and Morgan, RA (2009). Lack of specific gamma-retroviral vector long terminal repeat promoter silencing in patients receiving genetically engineered lymphocytes and activation upon lymphocyte restimulation. Blood 114: 2888-2899.
    • (2009) Blood , vol.114 , pp. 2888-2899
    • Burns, W.R.1    Zheng, Z.2    Rosenberg, S.A.3    Morgan, R.A.4
  • 33
    • 79955977180 scopus 로고    scopus 로고
    • Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia
    • Zhou, Q, Munger, ME, Veenstra, RG, Weigel, BJ, Hirashima, M, Munn, DH et al. (2011). Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia. Blood 117: 4501-4510.
    • (2011) Blood , vol.117 , pp. 4501-4510
    • Zhou, Q.1    Munger, M.E.2    Veenstra, R.G.3    Weigel, B.J.4    Hirashima, M.5    Munn, D.H.6
  • 34
    • 84864458660 scopus 로고    scopus 로고
    • Coinhibitory molecules in hematologic malignancies: Targets for therapeutic intervention
    • Norde, WJ, Hobo, W, van der Voort, R and Dolstra, H (2012). Coinhibitory molecules in hematologic malignancies: targets for therapeutic intervention. Blood 120: 728-736.
    • (2012) Blood , vol.120 , pp. 728-736
    • Norde, W.J.1    Hobo, W.2    Van Der Voort, R.3    Dolstra, H.4
  • 35
    • 0038153907 scopus 로고    scopus 로고
    • Cancer regression and autoimmunity induced by cytotoxic T lymphocyteassociated antigen 4 blockade in patients with metastatic melanoma
    • Phan, GQ, Yang, JC, Sherry, RM, Hwu, P, Topalian, SL, Schwartzentruber, DJ et al. (2003). Cancer regression and autoimmunity induced by cytotoxic T lymphocyteassociated antigen 4 blockade in patients with metastatic melanoma. Proc Natl Acad Sci USA 100: 8372-8377.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8372-8377
    • Phan, G.Q.1    Yang, J.C.2    Sherry, R.M.3    Hwu, P.4    Topalian, S.L.5    Schwartzentruber, D.J.6
  • 36
    • 38649094865 scopus 로고    scopus 로고
    • The heterogeneity of the kinetics of response to ipilimumab in metastatic melanoma: Patient cases
    • Saenger, YM and Wolchok, JD (2008). The heterogeneity of the kinetics of response to ipilimumab in metastatic melanoma: patient cases. Cancer Immun 8: 1.
    • (2008) Cancer Immun , vol.8 , pp. 1
    • Saenger, Y.M.1    Wolchok, J.D.2
  • 37
    • 34250223096 scopus 로고    scopus 로고
    • A pilot trial of CTLA-4 blockade with human anti-CTLA-4 in patients with hormone-refractory prostate cancer
    • Small, EJ, Tchekmedyian, NS, Rini, BI, Fong, L, Lowy, I and Allison, JP (2007). A pilot trial of CTLA-4 blockade with human anti-CTLA-4 in patients with hormone-refractory prostate cancer. Clin Cancer Res 13: 1810-1815.
    • (2007) Clin Cancer Res , vol.13 , pp. 1810-1815
    • Small, E.J.1    Tchekmedyian, N.S.2    Rini, B.I.3    Fong, L.4    Lowy, I.5    Allison, J.P.6


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