Lower dietary vitamin E intake during the second trimester is associated with insulin resistance and hyperglycemia later in pregnancy

European Journal of Clinical Nutrition

Volumn 67, Issue 11, 2013, Pages 1154-1156

  Ley, S H ^a,d   Hanley, A J ^a,b   Sermer, M ^b   Zinman, B ^a,b   O'Connor, D L ^a,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Hyperglycemia; Insulin resistance; Insulin sensitivity; Pregnancy; Vitamin E

Indexed keywords

ADIPONECTIN; ALPHA TOCOPHEROL; GLUCOSE; MULTIVITAMIN;

ADIPONECTIN BLOOD LEVEL; ADULT; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; DISEASE ASSOCIATION; FEMALE; GESTATION PERIOD; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HORMONE BLOOD LEVEL; HUMAN; HYPERGLYCEMIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MATERNAL NUTRITION; METABOLIC PARAMETERS; ORAL GLUCOSE TOLERANCE TEST; PREGNANT WOMAN; PROTEIN EXPRESSION; SECOND TRIMESTER PREGNANCY; VITAMIN INTAKE;

ADIPONECTIN; BLOOD GLUCOSE; DIABETES, GESTATIONAL; DIET; DIETARY SUPPLEMENTS; ENERGY INTAKE; FASTING; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; HYPERGLYCEMIA; INSULIN; INSULIN RESISTANCE; PREGNANCY; PREGNANCY TRIMESTER, SECOND; VITAMIN E; VITAMINS;

EID: 84887404732     PISSN: 09543007     EISSN: 14765640     Source Type: Journal    
DOI: 10.1038/ejcn.2013.185     Document Type: Article

References (10)

1. Butte NF. Carbohydrate and lipid metabolism in pregnancy: normal compared with gestational diabetes mellitus. Am J Clin Nutr 2000; 71: S1256-S1261.
2. Gray B, Swick J, Ronnenberg AG. Vitamin e and adiponectin: proposed mechanism for vitamin e-induced improvement in insulin sensitivity. Nutr Rev 2011; 69: 155-161.
3. Salonen JT, Nyyssonen K, Tuomainen T-P, Maenpaa PH, Korpela H, Kaplan GA et al. Increased risk of non-insulin dependent diabetes mellitus at low plasma vitamin e concentrations: A four year follow up study in men. BMJ 1995; 311: 1124-1127.
4. Montonen J, Knekt P, Järvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004; 27: 362-366. (Pubitemid 38174058)
5. Costacou T, Ma B, King IB, Mayer-Davis EJ. Plasma and dietary vitamin e in relation to insulin secretion and sensitivity. Diabetes Obes and Metab 2008; 10: 223-228. (Pubitemid 351247338)
6. Paolisso G, D'Amore A, Giugliano D, Ceriello A, Varricchio M, D'Onofrio F. Pharmacologic doses of vitamin e improve insulin action in healthy subjects and non-insulin-dependent diabetic patients. Am J Clin Nutr 1993; 57: 650-656. (Pubitemid 23132798)
7. Gagné A, Wei SQ, Fraser WD, Julien P. Absorption, transport, and bioavailability of vitamin e and its role in pregnant women. J Obstet Gynaecol Can 2009; 31: 210-217.
8. Ley SH, O'Connor DL, Retnakaran R, Hamilton J, Sermer M, Zinman B et al. Impact of maternal metabolic abnormalities in pregnancy on human milk and subsequent infant metabolic development: methodology and design. BMC Public Health 2010; 10: 590.
9. Ley SH, Hanley AJ, Retnakaran R, Sermer M, Zinman B, O'Connor DL. Effect of macronutrient intake during the second trimester on glucose metabolism later in pregnancy. Am J Clin Nutr 2011; 94: 1232-1240.
10. Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H et al. Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and-independent pathways. J Biol Chem 2006; 281: 8748-8755. (Pubitemid 43847980)