Ethnicity-tailored novel set of ESAT-6 peptides for differentiating active and latent tuberculosis

Tuberculosis

Volumn 93, Issue 6, 2013, Pages 618-624

  Singh, Salam Bhopen ^a   Biswas, Debasis ^a   Rawat, Jagdish ^a   Sindhwani, Girish ^a   Patras, Abhishek ^a   Devrani, Suraj ^a   Sarkar, Pronoti ^a   Mitra, Soumik ^a   Gupta, Shailendra K ^b  

^a HIMALAYAN INSTITUTE OF MEDICAL SCIENCES   (India)

^b CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Active tuberculosis; ESAT 6; Immunodiagnosis; Latent tuberculosis; Peptides

Indexed keywords

CULTURE FILTRATE PROTEIN 10; EARLY SECRETORY ANTIGENIC TARGET 6; GAMMA INTERFERON; INTERLEUKIN 4; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ASSAY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; LATENT TUBERCULOSIS; MALE; PRIORITY JOURNAL; TUBERCULOSIS;

ACTIVE TUBERCULOSIS; ATB; CFP-10; CULTURE FILTRATE PROTEIN 10; EARLY SECRETORY ANTIGENIC TARGET 6; ESAT-6; HEALTHY HOUSEHOLD CONTACT; HHC; IEDB; IMMUNE EPITOPE DATABASE; IMMUNODIAGNOSIS; INTERNATIONAL UNIT; IU; LATENT TUBERCULOSIS; MTB; MYCOBACTERIUM TUBERCULOSIS; OPD; OUTDOOR PATIENTS DEPARTMENT; PEPTIDES; PHA; PHYTOHAEMAGGLUTININ; PPD; PURIFIED PROTEIN DERIVATIVE; QFTGIT; QUANTIFERON TB GOLD IN TUBE; SD; SPSS; STANDARD DEVIATION; STATISTICAL PACKAGE FOR THE SOCIAL SCIENCES; TST; TUBERCULIN SKIN TEST;

ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; INDIA; INTERFERON-GAMMA; INTERFERON-GAMMA RELEASE TESTS; INTERLEUKIN-4; LATENT TUBERCULOSIS; MALE; MYCOBACTERIUM TUBERCULOSIS; PEPTIDE FRAGMENTS; PILOT PROJECTS; REAGENT KITS, DIAGNOSTIC; TUBERCULOSIS, PULMONARY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84887380606     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2013.08.001     Document Type: Article

References (40)

1. World Health Organization Global tuberculosis report 2012 Available at http://www.who.int/tb/publications/global-report/gtbr12-executivesummary.pdf [accessed on 30.04.13]
2. C. Dye, S. Scheele, P. Dolin, V. Pathania, and M.C. Raviglione Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO global surveillance and monitoring project JAMA 282 1999 677 686
3. K. Styblo Recent advances in epidemiological research in tuberculosis Adv Tuberc Res 20 1980 1 63
4. T. Connell, N. Bar-Zeev, and N. Curtis Early detection of perinatal tuberculosis using a whole blood interferon-gamma release assay Clin Infect Dis 42 2006 e82 e85
5. C.P. Simmons, G.E. Thwaites, N.T. Quyen, E. Torok, D.M. Hoang, T.T. Chau, P.P. Mai, N.T. Lan, N.H. Dung, H.T. Quy, N.D. Bang, T.T. Hien, and J. Farrar Pretreatment intracerebral and peripheral blood immune responses in Vietnamese adults with tuberculous meningitis: diagnostic value and relationship to disease severity and outcome J Immunol 176 2006 2007 2014
6. A. Lalvani, P. Nagvenkar, Z. Udwadia, A.A. Pathan, K.A. Wilkinson, J.S. Shastri, K. Ewer, A.V. Hill, A. Mehta, and C. Rodrigues Enumeration of T cells specific for RD1-encoded antigens suggests a high prevalence of latent Mycobacterium tuberculosis infection in healthy urban Indians J Infect Dis 183 2001 469 477
7. D. Vincenti, S. Carrara, P. De Mori, L.P. Pucillo, N. Petrosillo, F. Palmieri, O. Armignacco, G. Ippolito, E. Girardi, M. Amicosante, and D. Goletti Identification of early secretory antigen target-6 epitopes for the immunodiagnosis of active tuberculosis Mol Med 9 2003 105 111
8. E.M. Leyten, B. Mulder, C. Prins, K. Weldingh, P. Andersen, T.H. Ottenhoff, J.T. van Dissel, and S.M. Arend Use of enzyme-linked immunospot assay with Mycobacterium tuberculosis-specific peptides for diagnosis of recent infection with M tuberculosis after accidental laboratory exposure J Clin Microbiol 44 2006 1197 1201
9. Y. Kobashi, H. Shimizu, Y. Ohue, K. Mouri, Y. Obase, N. Miyashita, and M. Oka Comparison of T-cell interferon-gamma release assays for Mycobacterium tuberculosis-specific antigens in patients with active and latent tuberculosis Lung 188 2010 283 287
10. G.C. Macedo, A. Bozzi, H.R. Weinreich, A. Bafica, H.C. Teixeira, and S.C. Oliveira Human T cell and antibody-mediated responses to the Mycobacterium tuberculosis recombinant 85A, 85B, and ESAT-6 antigens Clin Dev Immunol 2011 2011 351573
11. A. Marei, A. Ghaemmaghami, P. Renshaw, M. Wiselka, M. Barer, M. Carr, and L. Ziegler-Heitbrock Superior T cell activation by ESAT-6 as compared with the ESAT-6-CFP-10 complex Int Immunol 17 2005 1439 1446
12. Z. Hasan, B. Jamil, M. Ashraf, M. Islam, M.S. Yusuf, J.A. Khan, and R. Hussain ESAT6-induced IFN gamma and CXCL9 can differentiate severity of tuberculosis PLoS One 4 2009 e5158
13. P. Ravn, M.E. Munk, A.B. Andersen, B. Lundgren, J.D. Lundgren, L.N. Nielsen, A. Kok-Jensen, P. Andersen, and K. Weldingh Prospective evaluation of a whole-blood test using Mycobacterium tuberculosis-specific antigens ESAT-6 and CFP-10 for diagnosis of active tuberculosis Clin Diagn Lab Immunol 12 2005 491 496
14. A. Lalvani, A.A. Pathan, H. McShane, R.J. Wilkinson, M. Latif, C.P. Conlon, G. Pasvol, and A.V. Hill Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells Am J Respir Crit Care Med 163 2001 824 828
15. A.S. Mustafa, R. Al-Attiyah, S.N. Hanif, and F.A. Shaban Efficient testing of large pools of Mycobacterium tuberculosis RD1 peptides and identification of major antigens and immunodominant peptides recognized by human Th1 cells Clin Vaccine Immunol 15 2008 916 924
16. A.A. Pathan, K.A. Wilkinson, P. Klenerman, H. McShane, R.N. Davidson, G. Pasvol, A.V. Hill, and A. Lalvani Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment J Immunol 167 2001 5217 5225
17. H.H. Lin, G.L. Zhang, S. Tongchusak, E.L. Reinherz, and V. Brusic Evaluation of MHC-II peptide binding prediction servers: applications for vaccine research BMC Bioinformatics 9 Suppl. 12 2008 S22
18. S.K. Gupta, M. Srivastava, B.A. Akhoon, S. Smita, U. Schmitz, O. Wolkenhauer, J. Vera, and S.K. Gupta Identification of immunogenic consensus T-cell epitopes in globally distributed influenza-A H1N1 neuraminidase Infect Genet Evol 11 2011 308 319
19. H.H. Bui, J. Sidney, K. Dinh, S. Southwood, M.J. Newman, and A. Sette Predicting population coverage of T-cell epitope-based diagnostics and vaccines BMC Bioinformatics 7 2006 153
20. T. Mori, M. Sakatani, F. Yamagishi, T. Takashima, Y. Kawabe, K. Nagao, E. Shigeto, N. Harada, S. Mitarai, M. Okada, K. Suzuki, Y. Inoue, K. Tsuyuguchi, Y. Sasaki, G.H. Mazurek, and I. Tsuyuguchi Specific detection of tuberculosis infection: an interferon-gamma-based assay using new antigens Am J Respir Crit Care Med 170 2004 59 64
21. J.S. Sutherland, B.C. de Jong, D.J. Jeffries, I.M. Adetifa, and M.O. Ota Production of TNF-alpha, IL-12(p40) and IL-17 can discriminate between active TB disease and latent infection in a West African cohort PLoS One 5 2010 e12365
22. P. Scarpellini, S. Tasca, L. Galli, A. Beretta, A. Lazzarin, and C. Fortis Selected pool of peptides from ESAT-6 and CFP-10 proteins for detection of Mycobacterium tuberculosis infection J Clin Microbiol 42 2004 3469 3474
23. C. Abramo, K.E. Meijgaarden, D. Garcia, K.L. Franken, M.R. Klein, A.J. Kolk, S.C. Oliveira, T.H. Ottenhoff, and H.C. Teixeira Monokine induced by interferon gamma and IFN-gamma response to a fusion protein of Mycobacterium tuberculosis ESAT-6 and CFP-10 in Brazilian tuberculosis patients Microbe. Infect 8 2006 45 51
24. I. Brock, M.E. Munk, A. Kok-Jensen, and P. Andersen Performance of whole blood IFN-gamma test for tuberculosis diagnosis based on PPD or the specific antigens ESAT-6 and CFP-10 Int J Tuberc Lung Dis 5 2001 462 467
25. T. Ulrichs, R. Anding, S.H. Kaufmann, and M.E. Munk Numbers of IFN-gamma-producing cells against ESAT-6 increase in tuberculosis patients during chemotherapy Int J Tuberc Lung Dis 4 2000 1181 1183
26. V. Sargentini, S. Mariotti, S. Carrara, M.C. Gagliardi, R. Teloni, D. Goletti, and R. Nisini Cytometric detection of antigen-specific IFN-gamma/IL-2 secreting cells in the diagnosis of tuberculosis BMC Infect Dis 9 2009 99
27. P.C. Hill, D. Jackson-Sillah, A. Fox, K.L. Franken, M.D. Lugos, D.J. Jeffries, S.A. Donkor, A.S. Hammond, R.A. Adegbola, T.H. Ottenhoff, M.R. Klein, and R.H. Brookes ESAT-6/CFP-10 fusion protein and peptides for optimal diagnosis of Mycobacterium tuberculosis infection by ex vivo enzyme-linked immunospot assay in the Gambia J Clin Microbiol 43 2005 2070 2074
28. S.M. Arend, A. Geluk, K.E. van Meijgaarden, J.T. van Dissel, M. Theisen, P. Andersen, and T.H. Ottenhoff Antigenic equivalence of human T-cell responses to Mycobacterium tuberculosis-specific RD1-encoded protein antigens ESAT-6 and culture filtrate protein 10 and to mixtures of synthetic peptides Infect Immun 68 2000 3314 3321
29. D. Goletti, D. Vincenti, S. Carrara, O. Butera, F. Bizzoni, G. Bernardini, M. Amicosante, and E. Girardi Selected RD1 peptides for active tuberculosis diagnosis: comparison of a gamma interferon whole-blood enzyme-linked immunosorbent assay and an enzyme-linked immunospot assay Clin Diagn Lab Immunol 12 2005 1311 1316
30. D. Goletti, O. Butera, F. Bizzoni, R. Casetti, E. Girardi, and F. Poccia Region of difference 1 antigen-specific CD4+ memory T cells correlate with a favorable outcome of tuberculosis J Infect Dis 194 2006 984 992
31. D. Goletti, S. Carrara, D. Vincenti, C. Saltini, E.B. Rizzi, V. Schininà, G. Ippolito, M. Amicosante, and E. Girardi Accuracy of an immune diagnostic assay based on RD1 selected epitopes for active tuberculosis in a clinical setting: a pilot study Clin Microbiol Infect 12 2006 544 550
32. A. Lalvani, R. Brookes, S. Hambleton, W.J. Britton, A.V. Hill, and A.J. McMichael Rapid effector function in CD8+ memory T cells J Exp Med 186 1997 859 865
33. M. Morosini, F. Meloni, M. Uccelli, A. Marone Bianco, N. Solari, and A.M. Fietta Ex vivo evaluation of PPD-specific IFN-gamma or IL-5 secreting cells in the peripheral blood and lungs of patients with tuberculosis Int J Tuberc Lung Dis 9 2005 753 759
34. D. Dlugovitzky, A. Torres-Morales, L. Rateni, M.A. Farroni, C. Largacha, O. Molteni, and O. Bottasso Circulating profile of Th1 and Th2 cytokines in tuberculosis patients with different degrees of pulmonary involvement FEMS Immunol Med Microbiol 18 1997 203 207
35. S.K. Sharma, D.K. Mitra, A. Balamurugan, R.M. Pandey, and N.K. Mehra Cytokine polarization in miliary and pleural tuberculosis J Clin Immunol 22 2002 345 352
36. T.J. Scriba, B. Kalsdorf, D.A. Abrahams, F. Isaacs, J. Hofmeister, G. Black, H.Y. Hassan, R.J. Wilkinson, G. Walzl, S.J. Gelderbloem, H. Mahomed, G.D. Hussey, and W.A. Hanekom Distinct, specific IL-17- and IL-22-producing CD4+ T cell subsets contribute to the human anti-mycobacterial immune response J Immunol 180 2008 1962 1970
37. I. Brock, K. Weldingh, E.M. Leyten, S.M. Arend, P. Ravn, and P. Andersen Specific T-cell epitopes for immunoassay-based diagnosis of Mycobacterium tuberculosis infection J Clin Microbiol 42 2004 2379 2387
38. A. Harari, V. Rozot, F.B. Enders, M. Perreau, J.M. Stalder, L.P. Nicod, M. Cavassini, T. Calandra, C.L. Blanchet, K. Jaton, M. Faouzi, C.L. Day, W.A. Hanekom, P.A. Bart, and G. Pantaleo Dominant TNF-α+ Mycobacterium tuberculosis-specific CD4+ T cell responses discriminate between latent infection and active disease Nat Med 17 2011 372 376
39. A. Fortes, K. Pereira, P.R. Antas, C.L. Franken, M. Dalcolmo, M.M. Ribeiro-Carvalho, K.S. Cunha, A. Geluk, A. Kritski, A. Kolk, P. Klatser, E.N. Sarno, T.H. Ottenhoff, and E.P. Sampaio Detection of in vitro interferon-gamma and serum tumour necrosis factor-alpha in multidrug-resistant tuberculosis patients Clin Exp Immunol 141 2005 541 548
40. A.J. Hughes, P. Hutchinson, T. Gooding, N.J. Freezer, S.R. Holdsworth, and P.D. Johnson Diagnosis of Mycobacterium tuberculosis infection using ESAT-6 and intracellular cytokine cytometry Clin Exp Immunol 142 2005 132 139