Urinary paraben concentrations and ovarian aging among women from a fertility center

Environmental Health Perspectives

Volumn 121, Issue 11-12, 2013, Pages 1299-1305

  Smith, Kristen W ^a   Souter, Irene ^b   Dimitriadis, Irene ^a,b   Ehrlich, Shelley ^a   Williams, Paige L ^a   Calafat, Antonia M ^c   Hauser, Russ ^a,b  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYBENZOIC ACID ESTER; BUTYL PARABEN; FOLLITROPIN; METHYL PARABEN; PROPYL PARABEN;

ADULT; AGE; AGING; ARTICLE; COHORT ANALYSIS; CONCENTRATION (PARAMETERS); ENVIRONMENTAL EXPOSURE; FEMALE; FERTILITY; FOLLOW UP; HUMAN; OUTCOME ASSESSMENT; OVARIAN RESERVE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SENSITIVITY ANALYSIS; URINALYSIS;

ADULT; BOSTON; COHORT STUDIES; ENVIRONMENTAL EXPOSURE; FEMALE; FOLLICLE STIMULATING HORMONE; HUMANS; INFERTILITY, FEMALE; LINEAR MODELS; OVARY; PARABENS; PRESERVATIVES, PHARMACEUTICAL; PROSPECTIVE STUDIES; URINE;

EID: 84887298912     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1205350     Document Type: Article

References (41)

1. Andersen FA. 2008. Final amended report on the safety assessment of methylparaben, ethylparaben, propylparaben, isopropylparaben, butylparaben, isobutylparaben, and benzylparaben as used in cosmetic products. Int J Toxicol 27(suppl 4):1-82.
2. Byford JR, Shaw LE, Drew MG, Pope GS, Sauer MJ, Darbre PD. 2002. Oestrogenic activity of parabens in MCF7 human breast cancer cells. J Steroid Biochem Mol Biol 80(1):49-60.
3. Calafat AM, Weuve J, Ye X, Jia LT, Hu H, Ringer S, et al. 2009. Exposure to bisphenol A and other phenols in neonatal intensive care unit premature infants. Environ Health Perspect 117:639-644; doi:10.1289/ehp.0800265.
4. Calafat AM, Ye X, Wong LY, Bishop AM, Needham LL. 2010. Urinary concentrations of four parabens in the U.S. population: NHANES 2005-2006. Environ Health Perspect 118:679-685; doi:10.1289/ehp.0901560.
5. Casas L, Fernandez MF, Llop S, Guxens M, Ballester F, Olea N, et al. 2011. Urinary concentrations of phthalates and phenols in a population of Spanish pregnant women and children. Environ Int 37(5):858-866.
6. CDC (Centers for Disease Control and Prevention). 2010a. 2008 Assisted Reproductive Technology Success Rates, National Summary and Fertility Clinic Reports. Available: http://www.cdc.gov/art/ART2008/PDF/ART_2008_Full.pdf [accessed 2 February 2012].
7. CDC (Centers for Disease Control and Prevention). 2010b. Laboratory Procedure Manual. Available: http://www.cdc.gov/nchs/data/nhanes/nhanes_07_08/EPH_E_met_phenols_parabens.pdf [accessed 18 July 2012].
8. Chandra A, Martinez GM, Mosher WD, Abma JC, Jones J. 2005. Fertility, family planning, and reproductive health of U.S. women: data from the 2002 National Survey of Family Growth. Vital Health Stat 23(25). Available: http://www.cdc.gov/nchs/data/series/sr_23/sr23_025.pdf [accessed 18 May 2011].
9. Crain DA, Janssen SJ, Edwards TM, Heindel J, Ho SM, Hunt P, et al. 2008. Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing. Fertil Steril 90(4):911-940.
10. Darbre PD, Harvey PW. 2008. Paraben esters: review of recent studies of endocrine toxicity, absorption, esterase and human exposure, and discussion of potential human health risks. J Appl Toxicol 28(5):561-578.
11. Duty SM, Ackerman RM, Calafat AM, Hauser R. 2005. Personal care product use predicts urinary concentrations of some phthalate monoesters. Environ Health Perspect 113:1530-1535; doi:10.1289/ehp.8083.
12. Elter K, Kavak ZN, Gokaslan H, Pekin T. 2005. Antral follicle assessment after down-regulation may be a useful tool for predicting pregnancy loss in in vitro fertilization pregnancies. Gynecol Endocrinol 21:33-37.
13. FDA (Food and Drug Administration). 2013. GRAS Substances (SCOGS) Database. Available: http://www.fda.gov/food/ingredientspackaginglabeling/gras/scogs/ucm2006852.htm [accessed 13 September 2013].
14. Golden R, Gandy J, Vollmer G. 2005. A review of the endocrine activity of parabens and implications for potential risks to human health. Crit Rev Toxicol 35(5):435-458.
15. Gomez E, Pillon A, Fenet H, Rosain D, Duchesne MJ, Nicolas JC, et al. 2005. Estrogenic activity of cosmetic components in reporter cell lines: parabens, UV screens, and musks. J Toxicol Environ Health A 68(4):239-251.
16. Hewitt SC, Harrell JC, Korach KS. 2005. Lessons in estrogen biology from knockout and transgenic animals. Annu Rev Physiol 67:285-308.
17. Hong Y, Wang J, Zhang P, Yang S, Song K, Yu F, et al. 2010. Histopathological and gene expression analysis of mice exposed to diethylstilbestrol. Toxicol Mech Methods 20(3):105-111.
18. Hornung R, Reed L. 1990. Estimation of average concentration in the presence of nondetectable values. Appl Occup Environ Hyg 5:46-51.
19. Janjua NR, Frederiksen H, Skakkebaek NE, Wulf HC, Andersson AM. 2008. Urinary excretion of phthalates and paraben after repeated whole-body topical application in humans. Int J Androl 31(2):118-130.
20. Kang KS, Che JH, Ryu DY, Kim TW, Li GX, Lee YS. 2002. Decreased sperm number and motile activity on the F1 offspring maternally exposed to butyl p-hydroxybenzoic acid (butyl paraben). J Vet Med Sci 64(3):227-235.
21. Levi AJ, Raynault MF, Bergh PA, Drews MR, Miller BT, Scott RT. 2001. Reproductive outcome in patients with diminished ovarian reserve. Fertil Steril 76:666-669.
22. Meeker JD, Yang T, Ye X, Calafat AM, Hauser R. 2011. Urinary concentrations of parabens and serum hormone levels, semen quality parameters, and sperm DNA damage. Environ Health Perspect 119:252-257; doi:10.1289/ehp.1002238.
23. Mok-Lin E, Ehrlich S, Williams PL, Petrozza J, Wright DL, Calafat AM, et al. 2010. Urinary bisphenol A concentrations and ovarian response among women undergoing IVF. Int J Androl 33(2):385-393.
24. National Toxicology Program. 2005. Butylparaben [CAS No. 94-26- 8]: Review of Toxicological Literature. Available: http://ntp.niehs.nih.gov/ntp/htdocs/Chem_Background/ExSumPdf/butylparaben_508.pdf [accessed 13 September 2013].
25. Orth DS. 1980. Use of parabens as cosmetic preservatives. Int J Dermatol 19(9):504-505.
26. Okubo T, Yokoyama Y, Kano K, Kano I. 2001. ER-dependent estrogenic activity of parabens assessed by proliferation of human breast cancer MCF-7 cells and expression of ERα and PR. Food Chem Toxicol 39(12):1225-1232.
27. Pasquali R, Pelusi C, Genghini S, Cacciari M, Gambineri A. 2003. Obesity and reproductive disorders in women. Hum Reprod Update 9(4):359-372.
28. Philippat C, Mortamais M, Chevrier C, Petit C, Calafat AM, Ye X, et al. 2012. Exposure to phthalates and phenols during pregnancy and offspring size at birth. Environ Health Perspect 120:464-470; doi:10.1289/ehp.1103634.
29. Rosen MP, Johnstone E, McCulloch CE, Schuh-Huerta SM, Sternfeld B, Reijo-Pera RA, et al. 2012. A characterization of the relationship of ovarian reserve markers with age. Fertil Steril 97(1):238-243.
30. Routledge EJ, Parker J, Odum J, Ashby J, Sumpter JP. 1998. Some alkyl hydroxy benzoate preservatives (parabens) are estrogenic. Toxicol Appl Pharmacol 153(1):12-19.
31. Safe SH. 1998. Hazard and risk assessment of chemical mixtures using the toxic equivalency factor approach. Environ Health Perspect 106(suppl 4):1051-1058.
32. Shah DK, Missmer SA, Berry KF, Racowsky C, Ginsburg ES. 2011. Effect of obesity on oocyte and embryo quality in women undergoing in vitro fertilization. Obstet Gynecol 118(1):63-70.
33. Shirai S, Suzuki Y, Yoshinaga J, Shiraishi H, Mizumoto Y. 2012. Urinary excretion of parabens in pregnant Japanese Women. Reprod Toxicol 35:96-101.
34. Smith KW, Braun JM, Williams PL, Ehrlich S, Correia KF, Calafat AM, et al. 2012. Predictors and variability of urinary paraben concentrations in men and women, including before and during pregnancy. Environ Health Perspect 120:1538-1543; doi:10.1289/ehp.1104614.
35. Soni MG, Carabin IG, Burdock GA. 2005. Safety assessment of esters of p-hydroxybenzoic acid (parabens). Food Chem Toxicol 43(7):985-1015.
36. Su HI, Sammel MD, Freeman EW, Lin H, DeBlasis T, Gracia CR. 2008. Body size affects measures of ovarian reserve in late reproductive age women. Menopause 15(5):857-861.
37. Taxvig C, Vinggaard AM, Hass U, Axelstad M, Boberg J, Hansen PR, et al. 2008. Do parabens have the ability to interfere with steroidogenesis? Toxicol Sci 106(1):206-213.
38. Vo TT, Yoo YM, Choi KC, Jeung EB. 2010. Potential estrogenic effect(s) of parabens at the prepubertal stage of a postnatal female rat model. Reprod Toxicol 29(3):306-316.
39. Wolff MS, Teitelbaum SL, Pinney SM, Windham G, Liao L, Biro F, et al. 2010. Investigation of relationships between urinary biomarkers of phytoestrogens, phthalates, and phenols and pubertal stages in girls. Environ Health Perspect 118:1039-1046; doi:10.1289/ehp.0901690.
40. Ye X, Bishop AM, Reidy JA, Needham LL, Calafat AM. 2006a. Parabens as urinary biomarkers of exposure in humans. Environ Health Perspect 114:1843-1846; doi:10.1289/ ehp.9413.
41. Ye X, Kuklenyik Z, Bishop AM, Needham LL, Calafat AM. 2006b. Quantification of the urinary concentrations of parabens in humans by on-line solid phase extraction-high performance liquid chromatography-isotope dilution tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 844(1):53-59.