Do parabens have the ability to interfere with steroidogenesis?

Toxicological Sciences

Volumn 106, Issue 1, 2008, Pages 206-213

  Taxvig, Camilla ^a   Vinggaard, Anne Marie ^a   Hass, Ulla ^a   Axelstad, Marta ^a   Boberg, Julie ^a   Hansen, Pernille Reimer ^a   Frederiksen, Hanne ^b   Nellemann, Christine ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b Rigshospitalet   (Denmark)

Author keywords

Butyl paraben; Developmental rat study; Endocrine disruption; Ethyl paraben; H295r assay; Steroidogenesis; T screen

Indexed keywords

4 HYDROXYBENZOIC ACID ESTER; AROMATASE; BENZODIAZEPINE RECEPTOR; BUTYL PARABEN; CHOLESTEROL; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); COMPLEMENT COMPONENT C3; CYTOCHROME P450C17; ENDOCRINE DISRUPTOR; ESTRADIOL RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ETHYL PARABEN; HORMONE RECEPTOR BLOCKING AGENT; HORMONE RECEPTOR STIMULATING AGENT; HYDROCORTISONE; LIOTHYRONINE; MESSENGER RNA; PROGESTERONE; RNA 18S; SCAVENGER RECEPTOR B; SOMATOMEDIN C; STEROID; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TESTOSTERONE; THYROID HORMONE RECEPTOR; THYROXINE;

ADRENAL GLAND; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL STRAIN GH3; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; FEMALE; FETUS; GESTATION PERIOD; HISTOPATHOLOGY; HORMONE DETERMINATION; IN VITRO STUDY; MALE; MITOCHONDRION; NEWBORN; NONHUMAN; PERINATAL DRUG EXPOSURE; PREGNANCY; PROGESTERONE SYNTHESIS; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEROIDOGENESIS; TESTOSTERONE SYNTHESIS;

ADRENAL GLANDS; ANIMALS; CELL LINE; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE DISRUPTORS; FEMALE; GESTATIONAL AGE; GONADAL STEROID HORMONES; MALE; OVARY; PARABENS; PHOSPHOPROTEINS; PITUITARY GLAND; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROGESTERONE; RATS; RATS, WISTAR; RECEPTORS, ESTRADIOL; RECEPTORS, GABA-A; RECEPTORS, THYROID HORMONE; RNA, MESSENGER; TESTIS; TESTOSTERONE;

RATTUS; RATTUS NORVEGICUS;

EID: 54349108893     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn148     Document Type: Article

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