Serum amyloid a differentially activates microglia and astrocytes via the PI3K pathway

Journal of Alzheimer's Disease

Volumn 38, Issue 1, 2014, Pages 133-144

  Yu, Yang ^a   Liu, Jin ^a   Li, Shu Qin ^a   Peng, Lei ^a   Ye, Richard D ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Alzheimer's disease; astrocytes; glial cells; microglia; serum amyloid A

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CD11B ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12P35; INTERLEUKIN 12P40; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 23P19; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; SERUM AMYLOID A; SN 50; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; ASTROCYTE CULTURE; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; G1 PHASE CELL CYCLE CHECKPOINT; GLIA CELL; GLIAL CELL CULTURE; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SENILE PLAQUE;

ALZHEIMER'S DISEASE; ASTROCYTES; GLIAL CELLS; MICROGLIA; SERUM AMYLOID A;

ANIMALS; ANTIGENS, CD11B; APOPTOSIS; ASTROCYTES; CELL CYCLE; CELLS, CULTURED; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; MICE; MICE, INBRED C57BL; MICROGLIA; PHOSPHATIDYLINOSITOL 3-KINASES; SERUM AMYLOID A PROTEIN; SIGNAL TRANSDUCTION; STATISTICS, NONPARAMETRIC; TIME FACTORS;

EID: 84887259150     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-130818     Document Type: Article

References (37)

1. Wyss-Coray T (2006) Inflammation in Alzheimer disease: Driving force, bystander or beneficial response? Nat Med 12, 1005-1015. (Pubitemid 44353380)
2. Streit WJ, Walter SA, Pennell NA (1999) Reactive microglio-sis. Prog Neurobiol 57, 563-581.
3. Tuppo EE, Arias HR (2005) The role of inflammation in Alzheimer's disease. Int J Biochem Cell Biol 37, 289-305. (Pubitemid 39330191)
4. Banati RB, Gehrmann J, Schubert P, Kreutzberg GW (1993) Cytotoxicity of microglia. Glia 7, 111-118.
5. Sofroniew MV, Vinters HV (2010) Astrocytes: Biology and pathology. Acta Neuropathol 119, 7-35.
6. Dong Y, Benveniste EN (2001) Immune function of astro-cytes. Glia 36, 180-190.
7. Chen Y, Swanson RA (2003) Astrocytes and brain injury. J Cereb Blood Flow Metab 23, 137-149. (Pubitemid 36188452)
8. Lee YJ, Han SB, Nam SY, Oh KW, Hong JT (2010) Inflammation and Alzheimer's disease. Arch Pharm Res 33, 1539-1556.
9. Kushner I (1982) The phenomenon of the acute phase response. Ann N Y Acad Sci 389, 39-48. (Pubitemid 12013176)
10. Banka CL, Yuan T, de Beer MC, Kindy M, Curtiss LK, de Beer FC (1995) Serum amyloid A (SAA): Influence on HDL-mediated cellular cholesterol efflux. J Lipid Res 36, 1058-1065.
11. Badolato R, Wang JM, Murphy WJ, Lloyd AR, Michiel DF, Bausserman LL, Kelvin DJ, Oppenheim JJ (1994) Serum amyloid A is a chemoattractant: Induction of migration, adhesion, and tissue infiltration of monocytes and polymor-phonuclear leukocytes. J Exp Med 180, 203-209. (Pubitemid 24181069)
12. Vallon R, Freuler F, Desta-Tsedu N, Robeva A, Dawson J, Wenner P, Engelhardt P, Boes L, Schnyder J, Tschopp C, Urfer R, Baumann G (2001) Serum amyloid A (apoSAA) expression is up-regulated in rheumatoid arthritis and induces transcription of matrix metalloproteinases. J Immunol 166, 2801-2807. (Pubitemid 32173521)
13. O'Hara R, Murphy EP, Whitehead AS, FitzGerald O, Bresni-han B (2004) Local expression of the serum amyloid A and formyl peptide receptor-like 1 genesin synovial tissue is associated with matrix metalloproteinase production in patients with inflammatory arthritis. Arthritis Rheum 50, 1788-1799. (Pubitemid 38725091)
14. Furlaneto CJ, Campa A (2000) A novel function of serum amyloidA: Apotent stimulus for the releaseoftumor necrosis factor-alpha, interleukin-1beta, and interleukin-8 by human blood neutrophil. Biochem Biophys Res Commun 268, 405-408. (Pubitemid 30119635)
15. He R, Sang H, Ye RD (2003) Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRL1/LXA4R. Blood 101, 1572-1581. (Pubitemid 36182537)
16. He R, Shepard LW, Chen J, Pan ZK, Ye RD (2006) Serum amyloid A is an endogenous ligand that differentially induces IL-12 and IL-23. J Immunol 177, 4072-4079. (Pubitemid 44359941)
17. Malle E, Sodin-Semrl S, Kovacevic A (2009) Serum amyloid A: An acute-phase protein involved in tumour pathogenesis. Cell Mol Life Sci 66, 9-26.
18. Liang JS, Sloane JA, Wells JM, Abraham CR, Fine RE, Sipe JD (1997) Evidence for local production of acute phase response apolipoprotein serum amyloid A in Alzheimer's disease brain. Neurosci Lett 225, 73-76. (Pubitemid 27166104)
19. Miida T, Yamada T, Seino U, Ito M, Fueki Y, Takahashi A, Kosuge K, Soda S, Hanyu O, Obayashi K, Miyazaki O, Okada M (2006) Serum amyloid A (SAA)-induced remodeling of CSF-HDL. Biochim Biophys Acta 1761, 424-433. (Pubitemid 43776455)
20. Kindy MS, Yu J, Guo JT, Zhu H (1999) Apolipoprotein Serum Amyloid A in Alzheimer's Disease. J Alzheimers Dis 1, 155-167.
21. Guo JT, Yu J, Grass D, de Beer FC, Kindy MS (2002) Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis. J Neurosci 22, 5900-5909. (Pubitemid 35387634)
22. Lu X, Ma L, Ruan L, Kong Y, Mou H, Zhang Z, Wang Z, Wang JM, Le Y (2010) Resveratrol differentially modulates inflammatory responses of microglia and astrocytes. J Neu-roinflammation 7, 46.
23. Hu J, Akama KT, Krafft GA, Chromy BA, Van Eldik LJ (1998) Amyloid-beta peptide activates cultured astrocytes: Morphological alterations, cytokine induction and nitric oxide release. Brain Res 785, 195-206. (Pubitemid 28179382)
24. Cheng N, He R, Tian J, Ye PP, Ye RD (2008) Cutting edge: TLR2 is a functional receptor for acute-phase serum amyloid A. J Immunol 181, 22-26.
25. Griffin WS (2006) Inflammation and neurodegenerative diseases. Am J Clin Nutr 83, 470S-474S. (Pubitemid 44713221)
26. Raivich G, Bohatschek M, Kloss CU, Werner A, Jones LL, Kreutzberg GW (1999) Neuroglial activation repertoire in the injured brain: Graded response, molecular mechanisms and cues to physiological function. Brain Res Brain Res Rev 30, 77-105. (Pubitemid 29331517)
27. Langmann T (2007) Microglia activation in retinal degeneration. J Leukoc Biol 81, 1345-1351. (Pubitemid 46827958)
28. Sandri S, Rodriguez D, Gomes E, Monteiro HP, Russo M, Campa A (2008) Is serum amyloid A an endogenous TLR4 agonist? J Leukoc Biol 83, 1174-1180. (Pubitemid 351960349)
29. Kho Y, Kim S, Yoon BS, Moon JH, Kim B, Kwak S, Woo J, Oh S, Hong K, Kim H, You S, Choi Y (2008) Induction of serum amyloid A genes is associated with growth and apoptosis of HC11 mammary epithelial cells. Biosci Biotechnol Biochem 72, 70-81. (Pubitemid 351158952)
30. Shainkin-Kestenbaum R, Zimlichman S, Lis M, Lidor C, Pomerantz M, Knyszynski A, Preciado-Patt L, Fridkin M (1996) Effect of serum amyloid A, HDL-apolipoprotein, on endothelial cell proliferation. Implication of an enigmatic protein to atherosclerosis. Biomed Pept Proteins Nucleic Acids 2, 79-84.
31. Peristeris P, Gaspar A, Gros P, Laurent P, Bernon H, Bienvenu J (1989) Effects of serum amyloid A protein on lymphocytes, HeLa, and MRC5 cells in culture. Biochem Cell Biol 67, 365-370. (Pubitemid 19220480)
32. Jo SH, Yun J, Kim JM, Lee C, Baek SH, Bae YS (2007) Serum amyloid A induces WISH cell apoptosis. Acta Pharmacol Sin 28, 73-80. (Pubitemid 46046629)
33. Christenson K, Bjorkman L, Tangemo C, Bylund J (2008) Serum amyloid A inhibits apoptosis of human neutrophils via a P2X7-sensitive pathway independent of formyl peptide receptor-like 1. J Leukoc Biol 83, 139-148.
34. 2-induced oxidative stress and apoptosis through upregulation of HO-1 expression via activation of the PI3K/Akt/Nrf2 pathway. Phytother Res, doi: 10. 1002/ptr. 4931.
35. Foey AD, Feldmann M, Brennan FM (2001) CD40 liga-tion induces macrophage IL-10 and TNF-alpha production: Differential use of the PI3K and p42/44 MAPK-pathways. Cytokine 16, 131-142. (Pubitemid 34112118)
36. Yu Y, Wang JR, Sun PH, Guo Y, Zhang ZJ, Jin GZ, Zhen X (2008) Neuroprotective effects of atypical D1 receptor agonist SKF83959 are mediated via D1 receptor-dependent inhibition of glycogen synthase kinase-3 beta and a receptor-independent anti-oxidative action. J Neurochem104, 946-956. (Pubitemid 351146579)
37. Tanner FC, Meier P, Greutert H, Champion C, Nabel EG, Luscher TF (2000) Nitric oxide modulates expression of cell cycle regulatory proteins: A cytostatic strategy for inhibition of human vascular smooth muscle cell proliferation. Circulation 101, 1982-1989. (Pubitemid 30225281)