Pharmacokinetics and tissue distribution of furanodiene W/O/W multiple emulsions in rats by a fast and sensitive HPLC-APCI-MS/MS method

Xenobiotica

Volumn 43, Issue 12, 2013, Pages 1095-1102

  Zhang, Li Feng ^a   Lu, Tao Tao ^a   Zhang, Shu Qiu ^a   Lin, Wen Han ^b   Li, Qing Shan ^a  

^a SHANXI MEDICAL UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

Furanodiene; LC APCI MS MS; Pharmacokinetics; Tissue distribution; W O W multiple emulsions

Indexed keywords

ANTINEOPLASTIC AGENT; CHINESE DRUG; FURANODIENE; FURAZOLIDONE; SESQUITERPENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; COMPARTMENT MODEL; CONTROLLED STUDY; DRUG HALF LIFE; DRUG TISSUE LEVEL; EMULSION; HEART; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KIDNEY; LIVER; LUNG; MALE; NONHUMAN; RAT; SMALL INTESTINE; SPLEEN; TANDEM MASS SPECTROMETRY; THERAPY EFFECT; TISSUE DISTRIBUTION;

ANIMALS; ATMOSPHERIC PRESSURE; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EMULSIONS; FURANS; FURAZOLIDONE; HETEROCYCLIC COMPOUNDS, 2-RING; INJECTIONS, INTRAVENOUS; LIVER; MALE; MASS SPECTROMETRY; OILS; RATS; RATS, WISTAR; REPRODUCIBILITY OF RESULTS; TIME FACTORS; TISSUE DISTRIBUTION; WATER;

EID: 84887253989     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2013.793434     Document Type: Article

References (27)

1. Albu F, Georgit C, David V, Medvedovici A. (2007). Determination of glibenclamide in human plasma by liquid chromatography and atmospheric pressure chemical ionization/MS-MS detection. J Chromatogr B 846:222-9.
2. Brieskorn CH, Noble P. (1983). Furanosesquiterpenes from the essential oil of myrrh. Phytochemistry 22:1207-11.
3. Cournarie F, Savelli M-P, Rosilio V, et al. (2004). Insulin-loaded W/O/W multiple emulsions: comparison of the performances of systems prepared with medium-chain-triglycerides and fish oil. Eur J Pharma Biopharm 58:477-82.
4. Erwin PM, López-Legentil S, Schuhmann PW. (2010). The pharmaceutical value of marine biodiversity for anti-cancer drug discovery. Ecol Econ 2:445-51.
5. Florence AT, Whitehill D. (1982). The formulation and stability of multiple emulsions. Int J Pharm 11:277-308.
6. Garti N, Aserin A. (1996). Double emulsions stabilized by macromolecular surfactants. Adv Coll Int Sci 65:37-69.
7. Haefner B. (2003). Drugs from the deep: marine natural products as drug candidates. Drug Discov Today 12:536-44.
8. Hauss DJ, Mehta SC, Radebaugh GW. (1994). Targeted lymphatic transport and modified systemic distribution of CI-976, a lipophilic lipid-regulator drug, via a formulation approach. Int J Pharm 108: 85-93.
9. Hikino H, Agatsuma K, Takemoto T. (1968). Furanodiene, a precursor of furan-containing sesquiterpenoids. Tetrahedron Lett 9:931-3.
10. Igarashi F, Hikiba J, Ogihara MH, et al. (2011). A highly specific and sensitive quantification analysis of the sterols in silkworm larvae by high performance liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry. Anal Biochem 419: 123-32.
11. Koga K, Takarada N, Takada K. (2010). Nano-sized water-in-oilin-water emulsion enhances intestinal absorption of calcein, a high solubility and low permeability compound. Eur J Pharma Biopharm 74:223-32.
12. Ma E, Wang X, Li Y, et al. (2008). Induction of apoptosis by furanodiene in HL60 leukemia cells through activation of TNFR1 signaling pathway. Cancer Lett 271:158-66.
13. Maradufu A, Warthen JD. (1988). Furanosesquiterpenoids from Commiphora myrrh oil. Plant Sci 57:181-4.
14. Matsuda H, Ninomiya K, Morikawa T, Yoshikawa M. (1998). Inhibitory effect and action mechanism of sesquiterpenes from zedoariae rhizome on galactosamine/lipopolysaccharide induced liver injury. Bioorg Med Chem Lett 8:339-44.
15. Mayer AMS, Rodŕguez AD, Berlinck RGS, Fusetani N. (2011). Marine pharmacology: marine compounds with antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous system, and other miscellaneous mechanisms of action. Comp Biochem Physiol C: Pharmacol Toxicol 153:191-222.
16. O'Driscoll CM, Myers RA, Stella VJ. (1991). Blood and lymph transport of DDT after oral and parenteral administration to anaesthetised rats. Int J Pharm 73:177-83.
17. Prabhakar K, Afzal SM, Kumar PU, et al. (2011). Brain delivery of transferrin coupled indinavir submicron lipid emulsions-pharmacokinetics and tissue distribution. Colloid Surface B 86: 305-13.
18. Rybak ME, Parker DL, Pfeiffer CM. (2008). Determination of urinary phytoestrogens by HPLC-MS/MS: a comparison of atmospheric pressure chemical ionization (APCI) and electrospray ionization (ESI). J Chromatogr B 861:145-50.
19. Song Q, Wen A, Ding L, et al. (2008). HPLC-APCI-MS for the determination of vitamin K1 in human plasma: method and clinical application. J Chromatogr B 875:541-5.
20. Vasiljevic D, Parojcic J, Primorac M, Vuleta G. (2006). An investigation into the characteristics and drug release properties of multiple W/O/W emulsion systems containing low concentration of lipophilic polymeric emulsifier. Int J Pharm 309:171-7.
21. Xiao Y, Yang F-Q, Li SP, et al. (2007). Furanodiene induces G2/M cell cycle arrest and apoptosis through MAPK signaling and mitochondria-caspase pathway in human hepatocellular carcinoma cells. Cancer Biol Ther 6:7-16.
22. Yang FQ, Li SP, Chen Y, et al. (2005). Identification and quantitation of eleven sesquiterpenes in three species of Curcuma rhizomes by pressurized liquid extraction and gas chromatography-mass spectrometry. J Pharmaceut Biomed 39:552-8.
23. Yang FQ, Li SP, Zhao J, et al. (2007). Optimization of GC-MS conditions based on resolution and stability of analytes for simultaneous determination of nine sesquiterpenoids in three species of Curcuma rhizomes. J Pharmaceut Biomed 43:73-82.
24. Yang FQ, Wang YT, Li SP. (2006). Simultaneous determination of 11 characteristic components in three species of Curcuma rhizomes using pressurized liquid extraction and high-performance liquid chromatography. J Chromatogr A 1134:226-31.
25. Yuan Z, Xu H, Wang K, et al. (2009). Determination of osthol and its metabolites in a phase I reaction system and the Caco-2 cell model by HPLC-UV and LC-MS/MS. J Pharmaceut Biomed 49: 1226-32.
26. Zhao YY, Cheng XL, Zhang YM, et al. (2010). A fast and sensitive HPLC-MS/MS analysis and preliminary pharmacokinetic characterization of ergone in rats. J Chromatogr B 878:29-33.
27. Zhong Z-F, Hoi P-M, Wu G-S, et al. (2012). Anti-angiogenic effect of furanodiene on HUVECs in vitro and on zebrafish in vivo. J Ethnopharmacol 141:721-7.