Calcium-calmodulin signaling elicits mitochondrial dysfunction and the release of cytochrome c during cadmium-induced apoptosis in primary osteoblasts

Toxicology Letters

Volumn 224, Issue 1, 2014, Pages 1-6

  Liu, Wei ^a   Zhao, Hongyan ^a   Wang, Yi ^a   Jiang, Chenyang ^a   Xia, Pengpeng ^a   Gu, Jianhong ^a   Liu, Xuezhong ^a   Bian, Jianchun ^a   Yuan, Yan ^a   Liu, Zongping ^a  

^a YANGZHOU UNIVERSITY   (China)

Author keywords

Apoptosis; Cadmium; Calcium; Calmodulin; Cytochrome c; Osteoblasts

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; CALCIUM; CALMODULIN; CASPASE 3; CHELATING AGENT; CYTOCHROME C; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL ISOLATION; CELL PROLIFERATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOSOL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ENZYME ACTIVITY; FLOW CYTOMETRY; INTRACELLULAR SIGNALING; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; SKULL; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

APOPTOSIS; CADMIUM; CALCIUM; CALMODULIN; CYTOCHROME C; OSTEOBLASTS;

ANIMALS; APOPTOSIS; CADMIUM; CALCIUM; CALCIUM SIGNALING; CALMODULIN; CELLS, CULTURED; CYTOCHROMES C; EGTAZIC ACID; MITOCHONDRIA; OSTEOBLASTS; RATS; RATS, SPRAGUE-DAWLEY; SULFONAMIDES;

EID: 84887252565     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.10.009     Document Type: Article

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