Crystal structure of rat intestinal alkaline phosphatase - Role of crown domain in mammalian alkaline phosphatases

Journal of Structural Biology

Volumn 184, Issue 2, 2013, Pages 182-192

  Ghosh, Kaushik ^a   Mazumder Tagore, Debarati ^a   Anumula, Rushith ^a   Lakshmaiah, Basanth ^a   Kumar, P P B S ^a   Singaram, Senthuran ^a   Matan, Thangavelu ^a   Kallipatti, Sanjith ^a   Selvam, Sabariya ^a   Krishnamurthy, Prasad ^a   Ramarao, Manjunath ^b  

^a SYNGENE INTERNATIONAL LTD   (India)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

Crown domain; Glycosylation; Metal ion requirements; Rat intestinal alkaline phosphatase structure

Indexed keywords

ALKALINE PHOSPHATASE; INTESTINE ENZYME; MAGNESIUM ION; PHOSPHATE; PRODRUG; ZINC ION;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CROWN DOMAIN; CRYSTAL STRUCTURE; DRUG METABOLISM; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME GLYCOSYLATION; ENZYME PURIFICATION; ENZYME STRUCTURE; ESCHERICHIA COLI; IN VITRO STUDY; INSECT CELL; MACACA FASCICULARIS; MOLECULAR CLONING; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RAT;

ESCHERICHIA COLI; HEXAPODA; INTRACISTERNAL A-PARTICLES; MACACA FASCICULARIS; MAMMALIA; RATTUS;

ALKALINE PHOSPHATASES; APS; CIAP; CROWN DOMAIN; CYNOMOLGUS MONKEY INTESTINAL ALKALINE PHOSPHATASE; ECAP; ESCHERICHIA COLI ALKALINE PHOSPHATASE; GCAP; GERM CELL ALKALINE PHOSPHATASE; GLYCOSYLATION; IAP; INTESTINAL ALKALINE PHOSPHATASE; MELTING TEMPERATURE; METAL ION REQUIREMENTS; N-ACETYL GLUCOSAMINE; NAG; P-NITROPHENYL-PHOSPHATE; PLACENTAL ALKALINE PHOSPHATASE; PLAP; PNPP; RAT INTESTINAL ALKALINE PHOSPHATASE; RAT INTESTINAL ALKALINE PHOSPHATASE EXPRESSED IN E. COLI; RAT INTESTINAL ALKALINE PHOSPHATASE EXPRESSED IN SF9 INSECT CELL; RAT INTESTINAL ALKALINE PHOSPHATASE STRUCTURE; RIAP; RIAP-EC; RIAP-IC; T(M); TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE; TM; TNAP; TRIPLE MUTANT;

ALKALINE PHOSPHATASE; AMINO ACID SUBSTITUTION; ANIMALS; CATALYTIC DOMAIN; COORDINATION COMPLEXES; CRYSTALLOGRAPHY, X-RAY; ENZYME STABILITY; HYDROGEN-ION CONCENTRATION; ISOENZYMES; KINETICS; MACACA FASCICULARIS; MAGNESIUM; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; RATS; SF9 CELLS; SPODOPTERA; ZINC;

EID: 84887230068     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2013.09.017     Document Type: Article

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