Major surface glycoproteins of insect forms of Trypanosoma brucei are not essential for cyclical transmission by tsetse

PLoS ONE

Volumn 4, Issue 2, 2009, Pages

  Vassella, Erik ^a   Oberle, Michael ^b   Urwyler, Simon ^a,c   Renggli, Christina Kunz ^b   Studer, Erwin ^a   Hemphill, Andrew ^a   Fragoso, Cristina ^a   Bütikofer, Peter ^a   Brun, Reto ^b   Roditi, Isabel ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^c ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN;

ARTICLE; COCULTURE; CONTROLLED STUDY; GENE DELETION; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; LIFE CYCLE; NONHUMAN; PARASITE TRANSMISSION; PLASMODIUM BERGHEI; PROTEIN DETERMINATION; STRAIN DIFFERENCE; SURVIVAL; TRYPANOSOMA BRUCEI; TSETSE FLY; WILD TYPE;

GLOSSINA (GENUS); HEXAPODA; PLASMODIUM BERGHEI; TRYPANOSOMA BRUCEI;

EID: 84887212417     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004493     Document Type: Article

References (40)

1. Bruce D (1896) Further report on the tsetse fly disease or nagana in Zululand. London: Harrison and Sons.
2. Roditi I, Liniger M (2002) Dressed for success: the surface coats of insect-borne protozoan parasites. Trends in Microbiol 10: 128-134.
3. Taylor JE, Rudenko G (2006) Switching trypanosome coats: what's in the wardrobe? Trends Genet 22: 614-620.
4. Urwyler S, Studer E, Renggli CK, Roditi I (2007) A family of stage-specific alanine-rich proteins on the surface of epimastigote forms of Trypanosoma brucei. Mol Microbiol 63: 218-228.
5. Nagamune K, Nozaki T, Maeda Y, Ohishi K, Fukuma T, et al. (2000) Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei. Proc Natl Acad Sci U S A 97: 10336-10341.
6. Sheader K, Vaughan S, Minchin J, Hughes K, Gull K, et al. (2005) Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes. Proc Natl Acad Sci U S A 102: 8716-8721.
7. Sbicego S, Vassella E, Kurath U, Blum B, Roditi I (1999) The use of transgenic Trypanosoma brucei to identify compounds inducing the differentiation of bloodstream forms to procyclic forms. Mol Biochem Parasitol 104: 311-322.
8. Brun R, Schoenenberger M (1981) Stimulating effect of citrate and cis-aconitate on the transformation of Trypanosoma brucei bloodstream forms to procyclic forms in vitro. Z Parasitenkd 66: 17-24.
9. Ziegelbauer K, Quinten M, Schwarz H, Pearson TW, Overath P (1990) Synchronous differentiation of Trypanosoma brucei from bloodstream to procyclic forms in vitro. Eur J Biochem 192: 373-378.
10. Gruszynski AE, van Deursen FJ, Albareda MC, Best A, Chaudhary K, et al. (2006) Regulation of surface coat exchange by differentiating African trypanosomes. Mol Biochem Parasitol 147: 211-223.
11. Grandgenett PM, Otsu K, Wilson HR, Wilson ME, Donelson JE (2007) A function for a specific zinc metalloprotease of African trypanosomes. PLoS Pathog 3: 1432-1445.
12. Acosta-Serrano A, Vassella E, Liniger M, Kunz Renggli C, Brun R, et al. (2001) The surface coat of procyclic Trypanosoma brucei: programmed expression and proteolytic cleavage of procyclin in the tsetse fly. Proc Natl Acad Sci U S A 98: 1513-1518.
13. Liniger M, Acosta-Serrano A, Van Den Abbeele J, Kunz Renggli C, Brun R, et al. (2003) Cleavage of trypanosome surface glycoproteins by alkaline trypsin-like enzyme(s) in the midgut of Glossina morsitans. Int J Parasitol 33: 1319-1328.
14. Liniger M, Urwyler S, Studer E, Oberle M, Renggli CK, et al. (2004) Role of the N-terminal domains of EP and GPEET procyclins in membrane targeting and the establishment of midgut infections by Trypanosoma brucei. Mol Biochem Parasitol 137: 247-251.
15. Vassella E, Acosta-Serrano A, Studer E, Lee SH, Englund PT, et al. (2001) Multiple procyclin isoforms are expressed differentially during the development of insect forms of Trypanosoma brucei. J Mol Biol 312: 597-607.
16. Vassella E, Den Abbeele JV, Bütikofer P, Renggli CK, Furger A, et al. (2000) A major surface glycoprotein of Trypanosoma brucei is expressed transiently during development and can be regulated post-transcriptionally by glycerol or hypoxia. Genes Dev 14: 615-626.
17. Sharma R, Peacock L, Gluenz E, Gull K, Gibson W, et al. (2007) Asymmetric Cell Division as a Route to Reduction in Cell Length and Change in Cell Morphology in Trypanosomes. Protist.
18. Urwyler S, Vassella E, Abbeele JV, Renggli CK, Blundell P, et al. (2005) Expression of Procyclin mRNAs during Cyclical Transmission of Trypanosoma brucei. PLoS Pathog 1: e22.
19. Hajduk SL (1984) Antigenic variation during the developmental cycle of Trypanosoma brucei. J Protozool 31: 41-47.
20. Vassella E, Bütikofer P, Engstler M, Jelk J, Roditi I (2003) Procyclin null mutants of Trypanosoma brucei express free glycosylphosphatidylinositols on their surface. Mol Biol Cell 14: 1308-1318.
21. Ruepp S, Furger A, Kurath U, Renggli CK, Hemphill A, et al. (1997) Survival of Trypanosoma brucei in the tsetse fly is enhanced by the expression of specific forms of procyclin. J Cell Biol 137: 1369-1379.
22. Lillico S, Field MC, Blundell P, Coombs GH, Mottram JC (2003) Essential Roles for GPI-anchored Proteins in African Trypanosomes Revealed Using Mutants Deficient in GPI8. Mol Biol Cell 14: 1182-1194.
23. Güther MLS, Lee S, Tetley L, Acosta-Serrano A, Ferguson MA (2006) GPI Anchored Proteins and Free GPI Glycolipids of Procyclic Form Trypanosoma brucei Are Nonessential for Growth, Are Required for Colonization of the Tsetse Fly, and Are Not the Only Components of the Surface Coat. Mol Biol Cell 17: 5265-5274.
24. Bütikofer P, Jelk J, Malherbe T, Vassella E, Acosta-Serrano A, et al. (2003) Phosphorylation of GPEET procyclin is not necessary for survival of Trypanosoma brucei procyclic forms in culture and in the tsetse fly midgut. Mol Biochem Parasitol 126: 287-291.
25. Haenni S, Renggli CK, Fragoso CM, Oberle M, Roditi I (2006) The procyclin-associated genes of Trypanosoma brucei are not essential for cyclical transmission by tsetse. Mol Biochem Parasitol 150: 144-156.
26. Tetley L, Turner CM, Barry JD, Crowe JS, Vickerman K (1987) Onset of expression of the variant surface glycoproteins of Trypanosoma brucei in the tsetse fly studied using immunoelectron microscopy. J Cell Sci 87(Pt 2): 363-372.
27. Nagamune K, Acosta-Serrano A, Uemura H, Brun R, Kunz-Renggli C, et al. (2004) Surface sialic acids taken from the host allow trypanosome survival in tsetse fly vectors. J Exp Med 199: 1445-1450.
28. Vassella E, Probst M, Schneider A, Studer E, Renggli CK, et al. (2004) Expression of a Major Surface Protein of Trypanosoma brucei Insect Forms Is Controlled by the Activity of Mitochondrial Enzymes. Mol Biol Cell 15: 3986-3993.
29. Schlaeppi AC, Malherbe T, Buütikofer P (2003) Coordinate expression of GPEET procyclin and its membrane-associated kinase in Trypanosoma brucei procyclic forms. J Biol Chem 278: 49980-49987.
30. Welburn SC, Maudlin I (1997) Control of Trypanosoma brucei brucei infections in tsetse, Glossina morsitans. Med Vet Entomol 11: 286-289.
31. Van Den Abbeele J, Claes Y, Van Bockstaele D, Le Ray D, Coosemans M (1999) Trypanosoma brucei spp. development in the tsetse fly: characterization of the post-mesocyclic stages in the foregut and proboscis. Parasitology 118: 469-478.
32. Chandra M, Liniger M, Tetley L, Roditi I, Barry JD (2004) TsetseEP, a gut protein from the tsetse Glossina morsitans, is related to a major surface glycoprotein of trypanosomes transmitted by the fly and to the products of a Drosophila gene family. Insect Biochem Mol Biol 34: 1163-1173.
33. Le Ray D, Barry JD, Easton C, Vickerman K (1977) First tsetse fly transmission of the "AnTat" serodeme of Trypanosoma brucei. Ann Soc Belg Med Trop 57: 369-381.
34. Vassella E, Kramer R, Turner CM, Wankell M, Modes C, et al. (2001) Deletion of a novel protein kinase with PX and FYVE-related domains increases the rate of differentiation of Trypanosoma brucei. Mol Microbiol 41: 33-46.
35. Brun R, Schoenenberger M (1979) Cultivation and in vitro cloning of procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Acta Tropica 36: 289-292.
36. Furger A, Schürch N, Kurath U, Roditi I (1997) Elements in the 3′ untranslated region of procyclin mRNA regulate expression in insect forms of Trypanosoma brucei by modulating RNA stability and translation. Mol Cell Biol 17: 4372-4380.
37. Helfert S, Estevez AM, Bakker B, Michels P, Clayton C (2001) Roles of triosephosphate isomerase and aerobic metabolism in Trypanosoma brucei. Biochem J 357: 117-125.
38. Bütikofer P, Ruepp S, Boschung M, Roditi I (1997) 'GPEET' procyclin is the major surface protein of procyclic culture forms of Trypanosoma brucei brucei strain 427. Biochem J 326: 415-423.
39. Richardson JP, Beecroft RP, Tolson DL, Liu MK, Pearson TW (1988) Procyclin: an unusual immunodominant glycoprotein surface antigen from the procyclic stage of African trypanosomes. Mol Biochem Parasitol 31: 203-216.
40. Furger A, Jungi TW, Salomone JY, Weynants V, Roditi I (2001) Stable expression of biologically active recombinant bovine interleukin- 4 in Trypanosoma brucei. FEBS Lett 508: 90-94.