Expression of procyclin mRNAs during cyclical transmission of Trypanosoma brucei

PLoS Pathogens

Volumn 1, Issue 3, 2005, Pages 0225-0231

  Urwyler, Simon ^a   Vassella, Erik ^a   Van Den Abbeele, Jan ^b   Renggli, Christina Kunz ^c   Blundell, Pat ^d   Barry, J David ^d   Roditi, Isabel ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^c SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GPEET PROTEIN, TRYPANOSOMA BRUCEI; MEMBRANE PROTEIN; MESSENGER RNA; PROCYCLIC ACIDIC REPETITIVE PROTEIN, TRYPANOSOMA; PROTOZOAL PROTEIN;

AFRICAN TRYPANOSOMIASIS; ANIMAL; ARTICLE; DISEASE TRANSMISSION; GENE; GENE EXPRESSION REGULATION; GENETICS; HISTOLOGY; HOST PARASITE INTERACTION; MALE; METABOLISM; MOUSE; MOUSE STRAIN; PARASITOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRYPANOSOMA BRUCEI; TSETSE FLY;

ANIMALS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, PROTOZOAN; HOST-PARASITE RELATIONS; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED STRAINS; PROTOZOAN PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN; TSETSE FLIES;

EID: 77951090060     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.0010022     Document Type: Article

References (38)

1. Imbuga MO, Osir EO, Labongo VL, Darji N, Otieno LH (1992) Studies on tsetse midgut factors that induce differentiation of blood-stream Trypanosoma brucei in vitro. Parasitol Res 78: 10-15.
2. Sbicego S, Vassella E, Kurath U, Blum B, Roditi I (1999) The use of transgenic Trypanosoma brucei to identify compounds inducing the differentiation of bloodstream forms to procyclic forms. Mol Biochem Parasitol 104: 311-322. (Pubitemid 29533316)
3. Vassella E, Den Abbeele JV, Bütikofer P, Renggli CK, Furger A, et al. (2000) A major surface glycoprotein of Trypanosoma brucei is expressed transiently during development and can be regulated post-transcriptionally by glycerol or hypoxia. Genes Dev 14: 615-626. (Pubitemid 30159780)
4. Van Den Abbeele J, Claes Y, Van Bockstaele D, Le Ray D, Coosemans M (1999) Trypanosoma brucei spp. development in the tsetse fly: Characterization of the post-mesocyclic stages in the foregut and proboscis. Parasitology 118: 469-478. (Pubitemid 29224616)
5. Barry JD, McCulloch R (2001) Antigenic variation in trypanosomes: Enhanced phenotypic variation in a eukaryotic parasite. Adv Parasitol 49: 1-70.
6. Roditi I, Schwarz H, Pearson TW, Beecroft RP, Liu MK, et al. (1989) Procyclin gene expression and loss of the variant surface glycoprotein during differentiation of Trypanosoma brucei. J Cell Biol 108: 737-746. (Pubitemid 19065869)
7. Ziegelbauer K, Quinten M, Schwarz H, Pearson TW, Overath P (1990) Synchronous differentiation of Trypanosoma brucei from bloodstream to procyclic forms in vitro. Eur J Biochem 192: 373-378. (Pubitemid 20283505)
8. Roditi I, Furger A, Ruepp S, Schürch N, Bütikofer P (1998) Unravelling the procyclin coat of Trypanosoma brucei. Mol Biochem Parasitol 91: 117-130. (Pubitemid 28241546)
9. Roditi I, Clayton C (1999) An unambiguous nomenclature for the major surface glycoproteins of the procyclic form of Trypanosoma brucei. Mol Biochem Parasitol 103: 99-100. (Pubitemid 29428232)
10. Acosta-Serrano A, Cole RN, Mehlert A, Lee MG, Ferguson MA, et al. (1999) The procyclin repertoire of Trypanosoma brucei. Identification and structural characterization of the glu-pro-rich polypeptides. J Biol Chem 274: 29763-29771. (Pubitemid 29483349)
11. Vassella E, Acosta-Serrano A, Studer E, Lee SH, Englund PT, et al. (2001) Multiple procyclin isoforms are expressed differentially during the development of insect forms of Trypanosoma brucei. J Mol Biol 312: 597-607. (Pubitemid 33116727)
12. Acosta-Serrano A, Vassella E, Liniger M, Kunz Renggli C, Brun R, et al. (2001) The surface coat of procyclic Trypanosoma brucei: Programmed expression and proteolytic cleavage of procyclin in the tsetse fly. Proc Natl Acad Sci U S A 98: 1513-1518. (Pubitemid 32165530)
13. Schlaeppi AC, Malherbe T, Butikofer P (2003) Coordinate expression of GPEET procyclin and its membrane-associated kinase in Trypanosoma brucei procyclic forms. J Biol Chem. 278: 49980-49987. (Pubitemid 37548834)
14. Bütikofer P, Vassella E, Ruepp S, Boschung M, Civenni G, et al. (1999) Phosphorylation of a major GPI-anchored surface protein of Trypanosoma brucei during transport to the plasma membrane. J Cell Sci 112: 1785-1795. (Pubitemid 29295054)
15. Vassella E, Probst M, Schneider A, Studer E, Renggli CK, et al. (2004) Expression of a major surface protein of Trypanosoma brucei insect forms is controlled by the activity of mitochondrial enzymes. Mol Biol Cell 15: 3986-3993. (Pubitemid 39122004)
16. Vickerman K, Tetley L, Hendry KA, Turner CM (1988) Biology of African trypanosomes in the tsetse fly. Biol Cell 64: 109-119.
17. Bütikofer P, Vassella E, Boschung M, Renggli CK, Brun R, et al. (2002) Glycosylphosphatidylinositol-anchored surface molecules of Trypanosoma congolense insect forms are developmentally regulated in the tsetse fly. Mol Biochem Parasitol 119: 7-16. (Pubitemid 34038020)
18. Thomson LM, Lamont DJ, Mehlert A, Barry JD, Ferguson MA (2002) Partial structure of GARP: A major surface glycoprotein of the insect stages of Trypanosoma congolense. J Biol Chem 277: 48899-48904.
19. Ruepp S, Furger A, Kurath U, Renggli CK, Hemphill A, et al. (1997) Survival of Trypanosoma brucei in the tsetse fly is enhanced by the expression of specific forms of procyclin. J Cell Biol 137: 1369-1379. (Pubitemid 27265948)
20. Bütikofer P, Jelk J, Malherbe T, Vassella E, Acosta-Serrano A, et al. (2003) Phosphorylation of GPEET procyclin is not necessary for survival of Trypanosoma brucei procyclic forms in culture and in the tsetse fly midgut. Mol Biochem Parasitol 126: 287-291. (Pubitemid 36255629)
21. Vanhamme L, Berberof M, Le Ray D, Pays E (1995) Stimuli of differentiation regulate RNA elongation in the transcription units for the major stage-specific antigens of Trypanosoma brucei. Nucleic Acids Res 23: 1862-1869.
22. Hehl A, Vassella E, Braun R, Roditi I (1994) A conserved stem-loop structure in the 3′ untranslated region of procyclin mRNAs regulates expression in Trypanosoma brucei. Proc Natl Acad Sci U S A 91: 370-374. (Pubitemid 24018706)
23. Furger A, Schürch N, Kurath U, Roditi I (1997) Elements in the 39 untranslated region of procyclin mRNA regulate expression in insect forms of Trypanosoma brucei by modulating RNA stability and translation. Mol Cell Biol 17: 4372-4380. (Pubitemid 27318114)
24. Schürch N, Furger A, Kurath U, Roditi I (1997) Contributions of the procyclin 39 untranslated region and coding region to the regulation of expression in bloodstream forms of Trypanosoma brucei. Mol Biochem Parasitol 89: 109-121. (Pubitemid 27373672)
25. Liniger M, Acosta-Serrano A, Van Den Abbeele J, Kunz Renggli C, Brun R, et al. (2003) Cleavage of trypanosome surface glycoproteins by alkaline trypsin-like enzyme(s) in the midgut of Glossina morsitans. Int J Parasitol 33: 1319-1328. (Pubitemid 37176977)
26. Gruszynski AE, DeMaster A, Hooper NM, Bangs JD (2003) Surface coat remodeling during differentiation of Trypanosoma brucei. J Biol Chem 278: 24665-24672. (Pubitemid 37548622)
27. Chandra M, Liniger M, Tetley L, Roditi I, Barry JD (2004) TsetseEP, a gut protein from the tsetse Glossina morsitans, is related to a major surface glycoprotein of trypanosomes transmitted by the fly and to the products of a Drosophila gene family. Insect Biochem Mol Biol 34: 1163-1173. (Pubitemid 39444400)
28. Engstler M, Boshart M (2004) Cold shock and regulation of surface protein trafficking convey sensitization to inducers of stage differentiation in Trypanosoma brucei. Genes Dev 18: 2798-2811. (Pubitemid 39507772)
29. Le Ray D, Barry JD, Easton C, Vickerman K (1977) First tsetse fly transmission of the "AnTat" serodeme of Trypanosoma brucei. Ann Soc Belg Med Trop 57: 369-381.
30. Delauw M-F, Pays E, Steinert M, Aerts D, Van Meirvenne N, et al. (1985) Inactivation and reactivation of a variant specific antigen gene in cyclically transmitted Trypanosoma brucei. EMBO J 4: 989-993.
31. Cunningham I (1977) New culture medium for maintenance of tsetse tissues and growth of trypanosomatids. J Protozool 24: 325-329.
32. Brun R, Schoenenberger M (1981) Stimulating effect of citrate and cisaconitate on the transformation of Trypanosoma brucei bloodstream forms to procyclic forms in vitro. Z Parasitenkd 66: 17-24. (Pubitemid 12174360)
33. Brun R, Schoenenberger M (1979) Cultivation and in vitro cloning of procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Acta Tropica 36: 289-292. (Pubitemid 10181444)
34. Roditi I, Carrington M, Turner M (1987) Expression of a polypeptide containing a dipeptide repeat is confined to the insect stage of Trypanosoma brucei. Nature 325: 272-274. (Pubitemid 17049890)
35. Sgaramella V, Khorana HG (1972) CXII. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining of the chemically synthesized polydeoxynucleotides to form the DNA duplex representing nucleotide sequence 1 to 20. J Mol Biol 72: 427-444.
36. Vassella E, Kramer R, Turner CM, Wankell M, Modes C, et al. (2001) Deletion of a novel protein kinase with PX and FYVE-related domains increases the rate of differentiation of Trypanosoma brucei. Mol Microbiol 41: 33-46. (Pubitemid 32660981)
37. Jefferies D, Tebabi P, Le Ray D, Pays E (1993) The ble resistance gene as a new selectable marker for Trypanosoma brucei: Fly transmission of stable procyclic transformants to produce antibiotic resistant bloodstream forms. Nucleic Acids Res 21: 191-195. (Pubitemid 23151886)
38. Richardson JP, Beecroft RP, Tolson DL, Liu MK, Pearson TW (1988) Procyclin: An unusual immunodominant glycoprotein surface antigen from the procyclic stage of African trypanosomes. Mol Biochem Parasitol 31: 203-216.