메뉴 건너뛰기




Volumn 19, Issue , 2013, Pages 2135-2150

An ophthalmic solution of a peroxisome proliferator-activated receptor gamma agonist prevents corneal inflammation in a rat alkali burn model

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANTIFIBROTIC AGENT; EYE DROPS; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PIOGLITAZONE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN A;

EID: 84887181014     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (35)

References (41)
  • 1
    • 13844297687 scopus 로고    scopus 로고
    • Beneficial effects of PPAR-gamma ligands in ischemia-reperfusion injury, inflammation and shock
    • [PMID: 15721857]
    • Abdelrahman M, Sivarajah A, Thiemermann C. Beneficial effects of PPAR-gamma ligands in ischemia-reperfusion injury, inflammation and shock. Cardiovasc Res 2005; 65:772-781. [PMID: 15721857].
    • (2005) Cardiovasc Res , vol.65 , pp. 772-781
    • Abdelrahman, M.1    Sivarajah, A.2    Thiemermann, C.3
  • 2
    • 0023913120 scopus 로고
    • The steroid and thyroid hormone receptor super-family
    • [PMID: 3283939]
    • Evans RM. The steroid and thyroid hormone receptor super-family. Science 1988; 240:889-895. [PMID: 3283939].
    • (1988) Science , vol.240 , pp. 889-895
    • Evans, R.M.1
  • 3
    • 84855209400 scopus 로고    scopus 로고
    • The peroxi-some proliferator-activated receptor: A family of nuclear receptors role in various diseases
    • [PMID: 22247890]
    • Tyagi S, Gupta P, Saini AS, Kaushal C, Sharma S. The peroxi-some proliferator-activated receptor: A family of nuclear receptors role in various diseases. J Adv Pharm Technol Res 2011; 2:236-240. [PMID: 22247890].
    • (2011) J Adv Pharm Technol Res , vol.2 , pp. 236-240
    • Tyagi, S.1    Gupta, P.2    Saini, A.S.3    Kaushal, C.4    Sharma, S.5
  • 4
    • 34547627893 scopus 로고    scopus 로고
    • PPARgamma in immunity and inflammation: Cell types and diseases
    • [PMID: 17418635]
    • Széles L, Töröcsik D, Nagy L. PPARgamma in immunity and inflammation: cell types and diseases. Biochim Biophys Acta 2007; 1771:1014-30. [PMID: 17418635].
    • (2007) Biochim Biophys Acta , vol.1771 , pp. 1014-1030
    • Széles, L.1    Töröcsik, D.2    Nagy, L.3
  • 5
    • 78650286735 scopus 로고    scopus 로고
    • The nuclear hormone receptor PPARγ as a therapeutic target in major diseases
    • [PMID: 210 57731]
    • Schmidt MV, Brüne B, von Knethen A. The nuclear hormone receptor PPARγ as a therapeutic target in major diseases. ScientificWorld Journal 2010; 10:2181-2197. [PMID: 210 57731].
    • (2010) ScientificWorld Journal , vol.10 , pp. 2181-2197
    • Schmidt, M.V.1    Brüne, B.2    von Knethen, A.3
  • 6
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • [PMID: 9422508]
    • Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 1998; 391:79-82. [PMID: 9422508].
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 7
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
    • [PMID: 9422509]
    • Jiang C, Ting AT, Seed B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 1998; 391:82-86. [PMID: 9422509].
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 8
    • 0041925176 scopus 로고    scopus 로고
    • PPARgamma-an important regu-lator of monocyte/macrophage function
    • [PMID: 12956430]
    • von Knethen A, Brüne B. PPARgamma-an important regu-lator of monocyte/macrophage function. Arch Immunol Ther Exp (Warsz) 2003; 51:219-226. [PMID: 12956430].
    • (2003) Arch Immunol Ther Exp (Warsz) , vol.51 , pp. 219-226
    • von Knethen, A.1    Brüne, B.2
  • 9
    • 58149335340 scopus 로고    scopus 로고
    • PPAR gamma ligands, rosiglitazone and pioglitazone, inhibit bFGF- and VEGF-mediated angiogenesis
    • [PMID: 18810 6 47]
    • Aljada A, O'Connor L, Fu Y Y, Mousa SA. PPAR gamma ligands, rosiglitazone and pioglitazone, inhibit bFGF- and VEGF-mediated angiogenesis. Angiogenesis 2008; 11:361-367. [PMID: 18810 6 47].
    • (2008) Angiogenesis , vol.11 , pp. 361-367
    • Aljada, A.1    O'Connor, L.2    Fu, Y.Y.3    Mousa, S.A.4
  • 10
    • 84872026309 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition-like phenotypic changes of retinal pigment epithelium induced by TGF-β are prevented by PPAR-γ agonists
    • [PMID: 22956604]
    • Hatanaka H, Koizumi N, Okumura N, Kay EP, Mizu-hara E, Hamuro J, Kinoshita S. Epithelial-mesenchymal transition-like phenotypic changes of retinal pigment epithelium induced by TGF-β are prevented by PPAR-γ agonists. Invest Ophthalmol Vis Sci 2012; 53:6955-6963. [PMID: 22956604].
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 6955-6963
    • Hatanaka, H.1    Koizumi, N.2    Okumura, N.3    Kay, E.P.4    Mizu-Hara, E.5    Hamuro, J.6    Kinoshita, S.7
  • 11
    • 84864947826 scopus 로고    scopus 로고
    • Pioglitazone, a peroxisome proliferator activated receptor γ agonist, decreases renal crystal deposition, oxida-tive stress and inflammation in hyperoxaluric rats
    • [PMID: 2 2819112]
    • Taguchi K, Okada A, Yasui T, Kobayashi T, Ando R, Tozawa K, Kohri K. Pioglitazone, a peroxisome proliferator activated receptor γ agonist, decreases renal crystal deposition, oxida-tive stress and inflammation in hyperoxaluric rats. J Urol 2012; 188:1002-1011. [PMID: 2 2819112].
    • (2012) J Urol , vol.188 , pp. 1002-1011
    • Taguchi, K.1    Okada, A.2    Yasui, T.3    Kobayashi, T.4    Ando, R.5    Tozawa, K.6    Kohri, K.7
  • 12
    • 84856100802 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ regulates inflammation and renin-angiotensin system activity in the hypothalamic paraventricular nucleus and ameliorates peripheral manifestations of heart failure
    • [PMID: 22 0 83161]
    • Yu Y, Zhang ZH, Wei SG, Weiss RM, Felder RB. Peroxisome proliferator-activated receptor-γ regulates inflammation and renin-angiotensin system activity in the hypothalamic paraventricular nucleus and ameliorates peripheral manifestations of heart failure. Hypertension 2012; 59:477-484. [PMID: 22 0 83161].
    • (2012) Hypertension , vol.59 , pp. 477-484
    • Yu, Y.1    Zhang, Z.H.2    Wei, S.G.3    Weiss, R.M.4    Felder, R.B.5
  • 13
    • 84869754865 scopus 로고    scopus 로고
    • Endothelial cell peroxisome proliferator-activated receptor γ reduces endotoxemic pulmonary inflammation and injury
    • [PMID: 23105142]
    • Reddy AT, Lakshmi SP, Kleinhenz JM, Sutliff RL, Hart CM, Reddy RC. Endothelial cell peroxisome proliferator-activated receptor γ reduces endotoxemic pulmonary inflammation and injury. J Immunol 2012; 189:5411-5420. [PMID: 23105142].
    • (2012) J Immunol , vol.189 , pp. 5411-5420
    • Reddy, A.T.1    Lakshmi, S.P.2    Kleinhenz, J.M.3    Sutliff, R.L.4    Hart, C.M.5    Reddy, R.C.6
  • 16
    • 84861081373 scopus 로고    scopus 로고
    • Pioglitazone attenuates vascular fibrosis in spontaneously hypertensive rats
    • [PMID: 22550475]
    • Gao D, Ning N, Hao G, Niu X. Pioglitazone attenuates vascular fibrosis in spontaneously hypertensive rats. PPAR Res 2012; 2012:856426-[PMID: 22550475].
    • (2012) PPAR Res , vol.2012 , pp. 856426
    • Gao, D.1    Ning, N.2    Hao, G.3    Niu, X.4
  • 17
    • 84863104065 scopus 로고    scopus 로고
    • PPARs at the crossroads of lipid signaling and inflammation
    • [PMID: 22704720]
    • Wahli W, Michalik L. PPARs at the crossroads of lipid signaling and inflammation. Trends Endocrinol Metab 2012; 23:351-363. [PMID: 22704720].
    • (2012) Trends Endocrinol Metab , vol.23 , pp. 351-363
    • Wahli, W.1    Michalik, L.2
  • 18
    • 0034889558 scopus 로고    scopus 로고
    • Vascular endothelial growth factor enhances glomerular capillary repair and accelerates resolution of experimentally induced glomerulonephritis
    • [PMID: 114 85918]
    • Masuda Y, Shimizu A, Mori T, Ishiwata T, Kitamura H, Ohashi R, Ishizaki M, Asano G, Sugisaki Y, Yamanaka N. Vascular endothelial growth factor enhances glomerular capillary repair and accelerates resolution of experimentally induced glomerulonephritis. Am J Pathol 2001; 159:599-608. [PMID: 114 85918].
    • (2001) Am J Pathol , vol.159 , pp. 599-608
    • Masuda, Y.1    Shimizu, A.2    Mori, T.3    Ishiwata, T.4    Kitamura, H.5    Ohashi, R.6    Ishizaki, M.7    Asano, G.8    Sugisaki, Y.9    Yamanaka, N.10
  • 19
    • 77956533073 scopus 로고    scopus 로고
    • Statin attenuates experimental anti-glomerular basement membrane glomerulonephritis together with the augmentation of alternatively activated macrophages
    • [PMID: 20696778]
    • Fujita E, Shimizu A, Masuda Y, Kuwahara N, Arai T, Naga-saka S, Aki K, Mii A, Natori Y, Iino Y, Katayama Y, Fukuda Y. Statin attenuates experimental anti-glomerular basement membrane glomerulonephritis together with the augmentation of alternatively activated macrophages. Am J Pathol 2010; 177:1143-1154. [PMID: 20696778].
    • (2010) Am J Pathol , vol.177 , pp. 1143-1154
    • Fujita, E.1    Shimizu, A.2    Masuda, Y.3    Kuwahara, N.4    Arai, T.5    Naga-Saka, S.6    Aki, K.7    Mii, A.8    Natori, Y.9    Iino, Y.10    Katayama, Y.11    Fukuda, Y.12
  • 20
    • 0036287669 scopus 로고    scopus 로고
    • Peritubular capillary regression during the progression of experimental obstructive nephropathy
    • [PMID: 12089375]
    • Ohashi R, Shimizu A, Masuda Y, Kitamura H, Ishizaki M, Sugisaki Y, Yamanaka N. Peritubular capillary regression during the progression of experimental obstructive nephropathy. J Am Soc Nephrol 2002; 13:1795-1805. [PMID: 12089375].
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1795-1805
    • Ohashi, R.1    Shimizu, A.2    Masuda, Y.3    Kitamura, H.4    Ishizaki, M.5    Sugisaki, Y.6    Yamanaka, N.7
  • 21
    • 16644387211 scopus 로고    scopus 로고
    • Vascular endothelial growth factor165 resolves glomerular inflammation and accelerates glomerular capillary repair in rat anti-glomerular basement membrane glomerulonephritis
    • [PMID: 15466270]
    • Shimizu A, Masuda Y, Mori T, Kitamura H, Ishizaki M, Sugi-saki Y, Fukuda Y. Vascular endothelial growth factor165 resolves glomerular inflammation and accelerates glomerular capillary repair in rat anti-glomerular basement membrane glomerulonephritis. J Am Soc Nephrol 2004; 15:2655-2665. [PMID: 15466270].
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2655-2665
    • Shimizu, A.1    Masuda, Y.2    Mori, T.3    Kitamura, H.4    Ishizaki, M.5    Sugi-Saki, Y.6    Fukuda, Y.7
  • 22
    • 0030956233 scopus 로고    scopus 로고
    • Optimizing collagen antigen unmasking in paraffin-embedded tissues
    • [PMID: 9088946]
    • Wakamatsu K, Ghazizadeh M, Ishizaki M, Fukuda Y, Yamanaka N. Optimizing collagen antigen unmasking in paraffin-embedded tissues. Histochem J 1997; 29:65-72. [PMID: 9088946].
    • (1997) Histochem J , vol.29 , pp. 65-72
    • Wakamatsu, K.1    Ghazizadeh, M.2    Ishizaki, M.3    Fukuda, Y.4    Yamanaka, N.5
  • 24
    • 24644463619 scopus 로고    scopus 로고
    • Alkali injuries of the eye
    • K rachmer JH, mannis MJ, Holland EJ, editors, 2nd Edition ed
    • Pfister RR, Pfister DR. Alkali injuries of the eye. In: K rachmer JH, mannis MJ, Holland EJ, editors. CORNEA. 2nd Edition ed 2005. p. 1285-1293.
    • (2005) CORNEA , pp. 1285-1293
    • Pfister, R.R.1    Pfister, D.R.2
  • 25
    • 0021676084 scopus 로고
    • Characteristics of poly-morphonuclear leukocyte infiltration into the alkali burned eye and the influence of sodium citrate
    • [PMID: 6097468]
    • Paterson CA, Williams RN, Parker AV. Characteristics of poly-morphonuclear leukocyte infiltration into the alkali burned eye and the influence of sodium citrate. Exp Eye Res 1984; 39:701-708. [PMID: 6097468].
    • (1984) Exp Eye Res , vol.39 , pp. 701-708
    • Paterson, C.A.1    Williams, R.N.2    Parker, A.V.3
  • 26
    • 0030955095 scopus 로고    scopus 로고
    • Chemical injuries of the eye: Current concepts in pathophysiology and therapy
    • [PMID: 910 4767]
    • Wagoner MD. Chemical injuries of the eye: current concepts in pathophysiology and therapy. Surv Ophthalmol 1997; 41: 275-313. [PMID: 910 4767].
    • (1997) Surv Ophthalmol , vol.41 , pp. 275-313
    • Wagoner, M.D.1
  • 27
    • 0023785785 scopus 로고
    • Citrate or ascorbate/citrate treatment of established corneal ulcers in the alkali-injured rabbit eye
    • [PMID: 3 4174 03]
    • Pfister RR, Haddox JL, Lank KM. Citrate or ascorbate/citrate treatment of established corneal ulcers in the alkali-injured rabbit eye. Invest Ophthalmol Vis Sci 1988; 29:1110-1115. [PMID: 3 4174 03].
    • (1988) Invest Ophthalmol Vis Sci , vol.29 , pp. 1110-1115
    • Pfister, R.R.1    Haddox, J.L.2    Lank, K.M.3
  • 28
    • 70449138788 scopus 로고
    • The structure and transparency of the cornea
    • [PMID: 13429485]
    • Maurice DM. The structure and transparency of the cornea. J Physiol 1957; 136:263-286. [PMID: 13429485].
    • (1957) J Physiol , vol.136 , pp. 263-286
    • Maurice, D.M.1
  • 29
    • 0029954960 scopus 로고    scopus 로고
    • Collagen types in healing alkali-burned corneal stroma in rabbits
    • [PMID: 8988 419]
    • Saika S, Ooshima A, Shima K, Tanaka S, Ohnishi Y. Collagen types in healing alkali-burned corneal stroma in rabbits. Jpn J Ophthalmol 1996; 40:303-309. [PMID: 8988 419].
    • (1996) Jpn J Ophthalmol , vol.40 , pp. 303-309
    • Saika, S.1    Ooshima, A.2    Shima, K.3    Tanaka, S.4    Ohnishi, Y.5
  • 30
    • 84855840646 scopus 로고    scopus 로고
    • Electro-philic PPARγ ligands inhibit corneal fibroblast to myofibro-blast differentiation in vitro: A potentially novel therapy for corneal scarring
    • [PMID: 22178 289]
    • Kuriyan AE, Lehmann GM, Kulkarni AA, Woeller CF, Feldon SE, Hindman HB, Sime PJ, Huxlin KR, Phipps RP. Electro-philic PPARγ ligands inhibit corneal fibroblast to myofibro-blast differentiation in vitro: a potentially novel therapy for corneal scarring. Exp Eye Res 2012; 94:136-145. [PMID: 22178 289].
    • (2012) Exp Eye Res , vol.94 , pp. 136-145
    • Kuriyan, A.E.1    Lehmann, G.M.2    Kulkarni, A.A.3    Woeller, C.F.4    Feldon, S.E.5    Hindman, H.B.6    Sime, P.J.7    Huxlin, K.R.8    Phipps, R.P.9
  • 31
    • 73449093533 scopus 로고    scopus 로고
    • Antifibrotic effect by activation of peroxisome proliferator-activated receptor-gamma in corneal fibroblasts
    • [PMID: 19936025]
    • Pan H, Chen J, Xu J, Chen M, Ma R. Antifibrotic effect by activation of peroxisome proliferator-activated receptor-gamma in corneal fibroblasts. Mol Vis 2009; 15:2279-2286. [PMID: 19936025].
    • (2009) Mol Vis , vol.15 , pp. 2279-2286
    • Pan, H.1    Chen, J.2    Xu, J.3    Chen, M.4    Ma, R.5
  • 32
    • 80052515078 scopus 로고    scopus 로고
    • Pioglitazone inhibits TGFβ induced keratocyte transformation to myofibroblast and extracellular matrix production
    • [PMID: 2112 79 91]
    • Pan HW, Xu JT, Chen JS. Pioglitazone inhibits TGFβ induced keratocyte transformation to myofibroblast and extracellular matrix production. Mol Biol Rep 2011; 38:4501-4508. [PMID: 2112 79 91].
    • (2011) Mol Biol Rep , vol.38 , pp. 4501-4508
    • Pan, H.W.1    Xu, J.T.2    Chen, J.S.3
  • 33
    • 70350502398 scopus 로고    scopus 로고
    • Effect of peroxisome proliferator-activated receptor gamma agonists on myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts
    • [PMID: 19894400]
    • Lee HM, Kang HJ, Park HH, Hong SC, Kim JK, Cho JH. Effect of peroxisome proliferator-activated receptor gamma agonists on myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts. Ann Otol Rhinol Laryngol 2009; 118:721-727. [PMID: 19894400].
    • (2009) Ann Otol Rhinol Laryngol , vol.118 , pp. 721-727
    • Lee, H.M.1    Kang, H.J.2    Park, H.H.3    Hong, S.C.4    Kim, J.K.5    Cho, J.H.6
  • 34
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heteroge-neity
    • [PMID: 16322748]
    • Gordon S, Taylor PR. Monocyte and macrophage heteroge-neity. Nat Rev Immunol 2005; 5:953-964. [PMID: 16322748].
    • (2005) Nat Rev Immunol , vol.5 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 35
    • 55849103960 scopus 로고    scopus 로고
    • Macrophage diversity in renal injury and repair
    • [PMID: 18982158]
    • Ricardo SD, van Goor H, Eddy AA. Macrophage diversity in renal injury and repair. J Clin Invest 2008; 118:3522-30. [PMID: 18982158].
    • (2008) J Clin Invest , vol.118 , pp. 3522-3530
    • Ricardo, S.D.1    van Goor, H.2    Eddy, A.A.3
  • 36
    • 0037310024 scopus 로고    scopus 로고
    • The many faces of macrophage activation
    • [PMID: 12554797]
    • Mosser DM. The many faces of macrophage activation. J Leukoc Biol 2003; 73:209-212. [PMID: 12554797].
    • (2003) J Leukoc Biol , vol.73 , pp. 209-212
    • Mosser, D.M.1
  • 38
    • 34547469630 scopus 로고    scopus 로고
    • Macrophage polarization and insulin resistance: PPARgamma in control
    • [PMID: 176 8114 4]
    • Charo IF. Macrophage polarization and insulin resistance: PPARgamma in control. Cell Metab 2007; 6:96-98. [PMID: 176 8114 4].
    • (2007) Cell Metab , vol.6 , pp. 96-98
    • Charo, I.F.1
  • 40
    • 30944439493 scopus 로고    scopus 로고
    • TGFbeta pathobiology in the eye
    • [PMID: 16 3 410 2 0]
    • Saika S. TGFbeta pathobiology in the eye. Lab Invest 2006; 8 6:106-115. [PMID: 16 3 410 2 0].
    • (2006) Lab Invest , vol.8 , Issue.6 , pp. 106-115
    • Saika, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.