-
1
-
-
84872967522
-
Cancer statistics
-
10.3322/caac.21166 23335087 10.3322/caac.21166
-
Siegel R, Naishadham D, Jemal A (2013) Cancer statistics. CA Cancer J Clin 63(1):11-30. doi: 10.3322/caac.21166
-
(2013)
CA Cancer J Clin
, vol.63
, Issue.1
, pp. 11-30
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
2
-
-
31444448873
-
Optimizing first-line treatment options for patients with advanced NSCLC
-
DOI 10.1634/theoncologist.10-90003-1
-
Wakelee H, Belani CP (2005) Optimizing first-line treatment options for patients with advanced NSCLC. Oncologist 10(Suppl 3):1-10. doi: 10.1634/theoncologist.10-90003-1 (Pubitemid 43152725)
-
(2005)
Oncologist
, vol.10
, Issue.SUPPL. 3
, pp. 1-10
-
-
Wakelee, H.1
Belani, C.P.2
-
3
-
-
84862781680
-
Quality of life in patients with advanced non-small-cell lung cancer given maintenance treatment with pemetrexed versus placebo (H3E-MC-JMEN): Results from a randomised, double-blind, phase 3 study
-
10.1016/s1470-2045(11)70339-4 22336221 1:CAS:528:DC%2BC38XjsVCgtr8%3D 10.1016/S1470-2045(11)70339-4
-
Belani CP, Brodowicz T, Ciuleanu TE, Krzakowski M, Yang SH, Franke F, Cucevic B, Madhavan J, Santoro A, Ramlau R, Liepa AM, Visseren-Grul C, Peterson P, John WJ, Zielinski CC (2012) Quality of life in patients with advanced non-small-cell lung cancer given maintenance treatment with pemetrexed versus placebo (H3E-MC-JMEN): results from a randomised, double-blind, phase 3 study. Lancet Oncol 13(3):292-299. doi: 10.1016/s1470-2045(11)70339-4
-
(2012)
Lancet Oncol
, vol.13
, Issue.3
, pp. 292-299
-
-
Belani, C.P.1
Brodowicz, T.2
Ciuleanu, T.E.3
Krzakowski, M.4
Yang, S.H.5
Franke, F.6
Cucevic, B.7
Madhavan, J.8
Santoro, A.9
Ramlau, R.10
Liepa, A.M.11
Visseren-Grul, C.12
Peterson, P.13
John, W.J.14
Zielinski, C.C.15
-
4
-
-
84857910629
-
Efficacy and safety of pemetrexed maintenance therapy versus best supportive care in patients from East Asia with advanced, nonsquamous non-small cell lung cancer: An exploratory subgroup analysis of a global, randomized, phase 3 clinical trial
-
10.1097/JTO.0b013e31823d4f9d 22157370 1:CAS:528:DC%2BC38Xls1Cisbo%3D 10.1097/JTO.0b013e31823d4f9d
-
Belani CP, Wu YL, Chen YM, Kim JH, Yang SH, Zhang L, Peterson P, Orlando M (2012) Efficacy and safety of pemetrexed maintenance therapy versus best supportive care in patients from East Asia with advanced, nonsquamous non-small cell lung cancer: an exploratory subgroup analysis of a global, randomized, phase 3 clinical trial. J Thorac Oncol 7(3):567-573. doi: 10.1097/JTO. 0b013e31823d4f9d
-
(2012)
J Thorac Oncol
, vol.7
, Issue.3
, pp. 567-573
-
-
Belani, C.P.1
Wu, Y.L.2
Chen, Y.M.3
Kim, J.H.4
Yang, S.H.5
Zhang, L.6
Peterson, P.7
Orlando, M.8
-
5
-
-
32944482800
-
A phase II trial of pemetrexed in advanced breast cancer: Clinical response and association with molecular target expression
-
DOI 10.1158/1078-0432.CCR-05-0295
-
Gomez HL, Santillana SL, Vallejos CS, Velarde R, Sanchez J, Wang X, Bauer NL, Hockett RD, Chen VJ, Niyikiza C, Hanauske AR (2006) A phase II trial of pemetrexed in advanced breast cancer: clinical response and association with molecular target expression. Clinical Cancer Res Off J Am Assoc Cancer Res 12(3 Pt 1):832-838. doi: 10.1158/1078-0432.CCR-05-0295 (Pubitemid 43259865)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.3
, pp. 832-838
-
-
Gomez, H.L.1
Santillana, S.L.2
Vallejos, C.S.3
Velarde, R.4
Sanchez, J.5
Wang, X.6
Bauer, N.L.7
Hockett, R.D.8
Chen, V.J.9
Niyikiza, C.10
Hanauske, A.R.11
-
6
-
-
1442290323
-
Thymidylate-synthase expression and prognosis in colorectal cancer: A systematic review and meta-analysis
-
DOI 10.1200/JCO.2004.05.064
-
Popat S, Matakidou A, Houlston RS (2004) Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis. J Clin Oncol 22(3):529-536. doi: 10.1200/JCO.2004.05.064 (Pubitemid 41079782)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.3
, pp. 529-536
-
-
Popat, S.1
Matakidou, A.2
Houlston, R.S.3
-
7
-
-
77951894575
-
Thymidylate synthase but not excision repair cross-complementation group 1 tumor expression predicts outcome in patients with malignant pleural mesothelioma treated with pemetrexed-based chemotherapy
-
10.1200/JCO.2009.25.9275 20177021 1:CAS:528:DC%2BC3cXltFGhtr8%3D 10.1200/JCO.2009.25.9275
-
Righi L, Papotti MG, Ceppi P, Billè A, Bacillo E, Molinaro L, Ruffini E, Scagliotti GV, Selvaggi G (2010) Thymidylate synthase but not excision repair cross-complementation group 1 tumor expression predicts outcome in patients with malignant pleural mesothelioma treated with pemetrexed-based chemotherapy. J Clin Oncol 28(9):1534-1539. doi: 10.1200/JCO.2009.25.9275
-
(2010)
J Clin Oncol
, vol.28
, Issue.9
, pp. 1534-1539
-
-
Righi, L.1
Papotti, M.G.2
Ceppi, P.3
Billè, A.4
Bacillo, E.5
Molinaro, L.6
Ruffini, E.7
Scagliotti, G.V.8
Selvaggi, G.9
-
8
-
-
84875388106
-
Thymidylate synthase and folyl-polyglutamate synthase are not clinically useful markers of response to pemetrexed in patients with malignant pleural mesothelioma
-
10.1097/JTO.0b013e318283da3e 23486267 1:CAS:528:DC%2BC3sXktVOisb0%3D 10.1097/JTO.0b013e318283da3e
-
Lustgarten DES, Deshpande C, Aggarwal C, Wang L-C, Saloura V, Vachani A, Wang L-P, Litzky L, Feldman M, Creaney J, Nowak AK, Langer C, Inghilleri S, Stella G, Albelda SM (2013) Thymidylate synthase and folyl-polyglutamate synthase are not clinically useful markers of response to pemetrexed in patients with malignant pleural mesothelioma. J Thorac Oncol 8(4):469-477. doi: 10.1097/JTO.0b013e318283da3e
-
(2013)
J Thorac Oncol
, vol.8
, Issue.4
, pp. 469-477
-
-
Lustgarten, D.E.S.1
Deshpande, C.2
Aggarwal, C.3
Wang, L.-C.4
Saloura, V.5
Vachani, A.6
Wang, L.-P.7
Litzky, L.8
Feldman, M.9
Creaney, J.10
Nowak, A.K.11
Langer, C.12
Inghilleri, S.13
Stella, G.14
Albelda, S.M.15
-
9
-
-
79960987500
-
Thymidylate synthase (TS) gene expression in primary lung cancer patients: A large-scale study in Japanese population
-
10.1093/annonc/mdq730 21321092 1:STN:280:DC%2BC3MjhsFOgsw%3D%3D 10.1093/annonc/mdq730
-
Tanaka F, Wada H, Fukui Y, Fukushima M (2011) Thymidylate synthase (TS) gene expression in primary lung cancer patients: a large-scale study in Japanese population. Ann Oncol 22(8):1791-1797. doi: 10.1093/annonc/mdq730
-
(2011)
Ann Oncol
, vol.22
, Issue.8
, pp. 1791-1797
-
-
Tanaka, F.1
Wada, H.2
Fukui, Y.3
Fukushima, M.4
-
10
-
-
67449091973
-
Updated clinical information on multitargeted antifolates in lung cancer
-
10.3816/CLC.2009.s.006 19362945 1:CAS:528:DC%2BD1MXkvFOltrk%3D 10.3816/CLC.2009.s.006
-
Scagliotti GV, Ceppi P, Capelletto E, Novello S (2009) Updated clinical information on multitargeted antifolates in lung cancer. Clin Lung Cancer 10(Suppl 1):S35-S40. doi: 10.3816/CLC.2009.s.006
-
(2009)
Clin Lung Cancer
, vol.10
, Issue.SUPPL. 1
-
-
Scagliotti, G.V.1
Ceppi, P.2
Capelletto, E.3
Novello, S.4
-
11
-
-
77949911427
-
Biological prognostic and predictive factors in lung cancer
-
10.1159/000258500 20130436 10.1159/000258500
-
Rossi A, Galetta D, Gridelli C (2009) Biological prognostic and predictive factors in lung cancer. Oncology 77(Suppl 1):90-96. doi: 10.1159/000258500
-
(2009)
Oncology
, vol.77
, Issue.SUPPL. 1
, pp. 90-96
-
-
Rossi, A.1
Galetta, D.2
Gridelli, C.3
-
12
-
-
46049107879
-
Thymidylate synthase in situ protein expression and survival in stage I nonsmall-cell lung cancer
-
DOI 10.1002/cncr.23491
-
Zheng Z, Li X, Schell MJ, Chen T, Boulware D, Robinson L, Sommers E, Bepler G (2008) Thymidylate synthase in situ protein expression and survival in stage I nonsmall-cell lung cancer. Cancer 112(12):2765-2773. doi: 10.1002/cncr.23491 (Pubitemid 351969222)
-
(2008)
Cancer
, vol.112
, Issue.12
, pp. 2765-2773
-
-
Zheng, Z.1
Li, X.2
Schell, M.J.3
Chen, T.4
Boulware, D.5
Robinson, L.6
Sommers, E.7
Bepler, G.8
-
13
-
-
79955813242
-
Thymidylate synthase as a determinant of pemetrexed sensitivity in non-small cell lung cancer
-
21487406 1:CAS:528:DC%2BC3MXlvFGgu7k%3D 10.1038/bjc.2011.129
-
Takezawa K, Okamoto I, Okamoto W, Takeda M, Sakai K, Tsukioka S, Kuwata K, Yamaguchi H, Nishio K, Nakagawa K (2011) Thymidylate synthase as a determinant of pemetrexed sensitivity in non-small cell lung cancer. Br J Cancer 104(10):1594-1601
-
(2011)
Br J Cancer
, vol.104
, Issue.10
, pp. 1594-1601
-
-
Takezawa, K.1
Okamoto, I.2
Okamoto, W.3
Takeda, M.4
Sakai, K.5
Tsukioka, S.6
Kuwata, K.7
Yamaguchi, H.8
Nishio, K.9
Nakagawa, K.10
-
14
-
-
77955097228
-
The efficacy of pemetrexed as a third- or fourth-line therapy and the significance of thymidylate synthase expression in patients with advanced non-small cell lung cancer
-
20061047 10.1016/j.lungcan.2009.12.002
-
Chang MH, Ahn JS, Lee J, Kim KH, Park YH, Han J, Ahn MJ, Park K (2010) The efficacy of pemetrexed as a third- or fourth-line therapy and the significance of thymidylate synthase expression in patients with advanced non-small cell lung cancer. Lung Cancer 69(3):323-329
-
(2010)
Lung Cancer
, vol.69
, Issue.3
, pp. 323-329
-
-
Chang, M.H.1
Ahn, J.S.2
Lee, J.3
Kim, K.H.4
Park, Y.H.5
Han, J.6
Ahn, M.J.7
Park, K.8
-
15
-
-
58949097480
-
Clinical efficacy and predictive molecular markers of neoadjuvant gemcitabine and pemetrexed in resectable non-small cell lung cancer
-
18827606 10.1097/JTO.0b013e3181874936
-
Bepler G, Sommers KE, Cantor A, Li X, Sharma A, Williams C, Chiappori A, Haura E, Antonia S, Tanvetyanon T, Simon G, Obasaju C, Robinson LA (2008) Clinical efficacy and predictive molecular markers of neoadjuvant gemcitabine and pemetrexed in resectable non-small cell lung cancer. J Thorac Oncol 3(10):1112-1118
-
(2008)
J Thorac Oncol
, vol.3
, Issue.10
, pp. 1112-1118
-
-
Bepler, G.1
Sommers, K.E.2
Cantor, A.3
Li, X.4
Sharma, A.5
Williams, C.6
Chiappori, A.7
Haura, E.8
Antonia, S.9
Tanvetyanon, T.10
Simon, G.11
Obasaju, C.12
Robinson, L.A.13
-
16
-
-
79955469120
-
Phase II study of pemetrexed and cisplatin, with chest radiotherapy followed by docetaxel in patients with stage III non-small cell lung cancer
-
10.1097/JTO.0b013e3182156109 21415776 10.1097/JTO.0b013e3182156109
-
Gadgeel SM, Ruckdeschel JC, Patel BB, Wozniak A, Konski A, Valdivieso M, Hackstock D, Chen W, Belzer K, Burger AM, Marquette L, Turrisi A (2011) Phase II study of pemetrexed and cisplatin, with chest radiotherapy followed by docetaxel in patients with stage III non-small cell lung cancer. J Thorac Oncol 6(5):927-933. doi: 10.1097/JTO.0b013e3182156109
-
(2011)
J Thorac Oncol
, vol.6
, Issue.5
, pp. 927-933
-
-
Gadgeel, S.M.1
Ruckdeschel, J.C.2
Patel, B.B.3
Wozniak, A.4
Konski, A.5
Valdivieso, M.6
Hackstock, D.7
Chen, W.8
Belzer, K.9
Burger, A.M.10
Marquette, L.11
Turrisi, A.12
-
17
-
-
34547450763
-
Practical methods for incorporating summary time-to-event data into meta-analysis
-
DOI 10.1186/1745-6215-8-16
-
Tierney JF, Stewart LA, Ghersi D, Burdett S, Sydes MR (2007) Practical methods for incorporating summary time-to-event data into meta-analysis. Trials 8:16. doi: 10.1186/1745-6215-8-16 (Pubitemid 47161711)
-
(2007)
Trials
, vol.8
, pp. 16
-
-
Tierney, J.F.1
Stewart, L.A.2
Ghersi, D.3
Burdett, S.4
Sydes, M.R.5
-
18
-
-
0041876133
-
Measuring inconsistency in meta-analyses
-
Higgins JPT, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327(7414):557-560. doi: 10.1136/bmj.327. 7414.557 (Pubitemid 37088507)
-
(2003)
British Medical Journal
, vol.327
, Issue.7414
, pp. 557-560
-
-
Higgins, J.P.T.1
Thompson, S.G.2
Deeks, J.J.3
Altman, D.G.4
-
19
-
-
0030922816
-
Bias in meta-analysis detected by a simple, graphical test
-
Egger M, Davey Smith G, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315(7109):629-634 (Pubitemid 27387172)
-
(1997)
British Medical Journal
, vol.315
, Issue.7109
, pp. 629-634
-
-
Egger, M.1
Smith, G.D.2
Schneider, M.3
Minder, C.4
-
20
-
-
84861337347
-
Thymidylate synthase protein expression by IHC and gene copy number by SISH correlate and show great variability in non-small cell lung cancer
-
10.1097/JTO.0b013e31824fe95a 22551903 1:CAS:528:DC%2BC38XhtVShtbjK 10.1097/JTO.0b013e31824fe95a
-
Wynes MW, Konopa K, Singh S, Reyna-Asuncion B, Ranger-Moore J, Sternau A, Christoph DC, Dziadziuszko R, Jassem J, Hirsch FR (2012) Thymidylate synthase protein expression by IHC and gene copy number by SISH correlate and show great variability in non-small cell lung cancer. J Thorac Oncol 7(6):982-992. doi: 10.1097/JTO.0b013e31824fe95a
-
(2012)
J Thorac Oncol
, vol.7
, Issue.6
, pp. 982-992
-
-
Wynes, M.W.1
Konopa, K.2
Singh, S.3
Reyna-Asuncion, B.4
Ranger-Moore, J.5
Sternau, A.6
Christoph, D.C.7
Dziadziuszko, R.8
Jassem, J.9
Hirsch, F.R.10
-
21
-
-
84655164992
-
Expression profiling-based subtyping identifies novel non-small cell lung cancer subgroups and implicates putative resistance to pemetrexed therapy
-
10.1097/JTO.0b013e3182352a45 22134068 1:CAS:528:DC%2BC38XjtFKjsrg%3D 10.1097/JTO.0b013e3182352a45
-
Hou J, Lambers M, den Hamer B, den Bakker MA, Hoogsteden HC, Grosveld F, Hegmans J, Aerts J, Philipsen S (2012) Expression profiling-based subtyping identifies novel non-small cell lung cancer subgroups and implicates putative resistance to pemetrexed therapy. J Thorac Oncol 7(1):105-114. doi: 10.1097/JTO.0b013e3182352a45
-
(2012)
J Thorac Oncol
, vol.7
, Issue.1
, pp. 105-114
-
-
Hou, J.1
Lambers, M.2
Den Hamer, B.3
Den Bakker, M.A.4
Hoogsteden, H.C.5
Grosveld, F.6
Hegmans, J.7
Aerts, J.8
Philipsen, S.9
-
22
-
-
84866173015
-
Pharmacogenetic study of patients with advanced non-small cell lung cancer (NSCLC) treated with second-line pemetrexed or pemetrexed-carboplatin
-
10.1016/j.lungcan.2012.07.009 22889494 10.1016/j.lungcan.2012.07.009
-
Tiseo M, Giovannetti E, Tibaldi C, Camerini A, Di Costanzo F, Barbieri F, Burgers JA, Vincent A, Peters GJ, Smit EF, Ardizzoni A (2012) Pharmacogenetic study of patients with advanced non-small cell lung cancer (NSCLC) treated with second-line pemetrexed or pemetrexed-carboplatin. Lung Cancer 78(1):92-99. doi: 10.1016/j.lungcan.2012.07.009
-
(2012)
Lung Cancer
, vol.78
, Issue.1
, pp. 92-99
-
-
Tiseo, M.1
Giovannetti, E.2
Tibaldi, C.3
Camerini, A.4
Di Costanzo, F.5
Barbieri, F.6
Burgers, J.A.7
Vincent, A.8
Peters, G.J.9
Smit, E.F.10
Ardizzoni, A.11
-
23
-
-
84864306550
-
Biomarker analysis in a phase III study of pemetrexed-carboplatin versus etoposide-carboplatin in chemonaive patients with extensive-stage small-cell lung cancer
-
22186609 1:STN:280:DC%2BC38zptFCrtw%3D%3D 10.1093/annonc/mdr563
-
Smit EF, Socinski MA, Mullaney BP, Myrand SP, Scagliotti GV, Lorigan P, Reck M, Ciuleanu T, von Pawel J, Karaseva NA, Szczesna A, Ohannesian D, Powell E, Hozak RR, Hong S, Guba SC, Thatcher N (2012) Biomarker analysis in a phase III study of pemetrexed-carboplatin versus etoposide-carboplatin in chemonaive patients with extensive-stage small-cell lung cancer. Ann Oncol 23(7):1723-1729
-
(2012)
Ann Oncol
, vol.23
, Issue.7
, pp. 1723-1729
-
-
Smit, E.F.1
Socinski, M.A.2
Mullaney, B.P.3
Myrand, S.P.4
Scagliotti, G.V.5
Lorigan, P.6
Reck, M.7
Ciuleanu, T.8
Von Pawel, J.9
Karaseva, N.A.10
Szczesna, A.11
Ohannesian, D.12
Powell, E.13
Hozak, R.R.14
Hong, S.15
Guba, S.C.16
Thatcher, N.17
-
24
-
-
65349091355
-
Randomized phase II and pharmacogenetic study of pemetrexed compared with pemetrexed plus carboplatin in pretreated patients with advanced non-small-cell lung cancer
-
10.1200/JCO.2008.19.1650 19307503 1:CAS:528:DC%2BD1MXls1CgtLY%3D 10.1200/JCO.2008.19.1650
-
Smit EF, Burgers SA, Biesma B, Smit HJM, Eppinga P, Dingemans A-MC, Joerger M, Schellens JH, Vincent A, van Zandwijk N, Groen HJM (2009) Randomized phase II and pharmacogenetic study of pemetrexed compared with pemetrexed plus carboplatin in pretreated patients with advanced non-small-cell lung cancer. J Clin Oncol 27(12):2038-2045. doi: 10.1200/JCO.2008.19.1650
-
(2009)
J Clin Oncol
, vol.27
, Issue.12
, pp. 2038-2045
-
-
Smit, E.F.1
Burgers, S.A.2
Biesma, B.3
Smit, H.J.M.4
Eppinga, P.5
Dingemans, A.-M.6
Joerger, M.7
Schellens, J.H.8
Vincent, A.9
Van Zandwijk, N.10
Groen, H.J.M.11
-
25
-
-
84867272757
-
Correlation between thymidylate synthase gene polymorphisms and efficacy of pemetrexed in advanced non-small cell lung cancer
-
23226765 1:CAS:528:DC%2BC38XhvVKgtLrK
-
Hu Q, Li X, Su C, Chen X, Gao G, Zhang J, Zhao Y, Li J, Zhou C (2012) Correlation between thymidylate synthase gene polymorphisms and efficacy of pemetrexed in advanced non-small cell lung cancer. Exp Ther Med 4(6):1010-1016
-
(2012)
Exp Ther Med
, vol.4
, Issue.6
, pp. 1010-1016
-
-
Hu, Q.1
Li, X.2
Su, C.3
Chen, X.4
Gao, G.5
Zhang, J.6
Zhao, Y.7
Li, J.8
Zhou, C.9
-
26
-
-
84874413584
-
Polymorphisms in thymidylate synthase and reduced folate carrier (SLC19A1) genes predict survival outcome in advanced non-small cell lung cancer patients treated with pemetrexed-based chemotherapy
-
23599757 1:CAS:528:DC%2BC3sXms1Kit7k%3D
-
Li WJ, Jiang H, Fang XJ, Ye HL, Liu MH, Liu YW, Chen Q, Zhang L, Zhang JY, Yuan CL, Zhang QY (2013) Polymorphisms in thymidylate synthase and reduced folate carrier (SLC19A1) genes predict survival outcome in advanced non-small cell lung cancer patients treated with pemetrexed-based chemotherapy. Oncol Lett 5(4):1165-1170
-
(2013)
Oncol Lett
, vol.5
, Issue.4
, pp. 1165-1170
-
-
Li, W.J.1
Jiang, H.2
Fang, X.J.3
Ye, H.L.4
Liu, M.H.5
Liu, Y.W.6
Chen, Q.7
Zhang, L.8
Zhang, J.Y.9
Yuan, C.L.10
Zhang, Q.Y.11
-
27
-
-
84872806269
-
Association of thymidylate synthase gene 3′-untranslated region polymorphism with sensitivity of non-small cell lung cancer to pemetrexed treatment: TS gene polymorphism and pemetrexed sensitivity in NSCLC
-
Wang X, Wang Y, Wang Y, Cheng J, Wang Y, Ha M (2013) Association of thymidylate synthase gene 3′-untranslated region polymorphism with sensitivity of non-small cell lung cancer to pemetrexed treatment: TS gene polymorphism and pemetrexed sensitivity in NSCLC. J Biomed Sci 20(1)
-
(2013)
J Biomed Sci
, vol.20
, Issue.1
-
-
Wang, X.1
Wang, Y.2
Wang, Y.3
Cheng, J.4
Wang, Y.5
Ha, M.6
-
28
-
-
84867772090
-
Association between expression of thymidylate synthase, dihydrofolate reductase, and glycinamide ribonucleotide formyltransferase and efficacy of pemetrexed in advanced non-small cell lung cancer
-
23060591 1:CAS:528:DC%2BC38Xhs1ygtbfK
-
Shimizu T, Nakanishi Y, Nakagawa Y, Tsujino I, Takahashi N, Nemoto N, Hashimoto S (2012) Association between expression of thymidylate synthase, dihydrofolate reductase, and glycinamide ribonucleotide formyltransferase and efficacy of pemetrexed in advanced non-small cell lung cancer. Anticancer Res 32(10):4589-4596
-
(2012)
Anticancer Res
, vol.32
, Issue.10
, pp. 4589-4596
-
-
Shimizu, T.1
Nakanishi, Y.2
Nakagawa, Y.3
Tsujino, I.4
Takahashi, N.5
Nemoto, N.6
Hashimoto, S.7
-
29
-
-
84871950953
-
Significance of folate receptor alpha and thymidylate synthase protein expression in patients with non-small-cell lung cancer treated with pemetrexed
-
23242435 1:CAS:528:DC%2BC38XhvVCqtLfM 10.1097/JTO.0b013e31827628ff
-
Christoph DC, Asuncion BR, Hassan B, Tran C, Maltzman JD, O'Shannessy DJ, Wynes MW, Gauler TC, Wohlschlaeger J, Hoiczyk M, Schuler M, Eberhardt WE, Hirsch FR (2013) Significance of folate receptor alpha and thymidylate synthase protein expression in patients with non-small-cell lung cancer treated with pemetrexed. J Thorac Oncol 8(1):19-30
-
(2013)
J Thorac Oncol
, vol.8
, Issue.1
, pp. 19-30
-
-
Christoph, D.C.1
Asuncion, B.R.2
Hassan, B.3
Tran, C.4
Maltzman, J.D.5
O'Shannessy, D.J.6
Wynes, M.W.7
Gauler, T.C.8
Wohlschlaeger, J.9
Hoiczyk, M.10
Schuler, M.11
Eberhardt, W.E.12
Hirsch, F.R.13
-
30
-
-
84868607952
-
Pemetrexed for previously treated patients with non-small cell lung cancer and differences in efficacy according to thymidylate synthase expression
-
23147191 1:CAS:528:DC%2BC38XhslyjsLrF 10.1159/000343048
-
Igawa S, Ryuge S, Wada M, Otani S, Maki S, Takakura A, Katono K, Sasaki J, Sato Y, Masuda N (2012) Pemetrexed for previously treated patients with non-small cell lung cancer and differences in efficacy according to thymidylate synthase expression. Chemotherapy 58(4):313-320
-
(2012)
Chemotherapy
, vol.58
, Issue.4
, pp. 313-320
-
-
Igawa, S.1
Ryuge, S.2
Wada, M.3
Otani, S.4
Maki, S.5
Takakura, A.6
Katono, K.7
Sasaki, J.8
Sato, Y.9
Masuda, N.10
-
31
-
-
80051785282
-
Significance of thymidylate synthase and thyroid transcription factor 1 expression in patients with nonsquamous non-small cell lung cancer treated with pemetrexed-based chemotherapy
-
10.1097/JTO.0b013e3182208ea8 21716147 10.1097/JTO.0b013e3182208ea8
-
Sun J-M, Han J, Ahn JS, Park K, Ahn M-J (2011) Significance of thymidylate synthase and thyroid transcription factor 1 expression in patients with nonsquamous non-small cell lung cancer treated with pemetrexed-based chemotherapy. J Thorac Oncol 6(8):1392-1399. doi: 10.1097/JTO.0b013e3182208ea8
-
(2011)
J Thorac Oncol
, vol.6
, Issue.8
, pp. 1392-1399
-
-
Sun, J.-M.1
Han, J.2
Ahn, J.S.3
Park, K.4
Ahn, M.-J.5
-
32
-
-
80052554890
-
Thymidylate synthase and dihydrofolate reductase expression in non-small cell lung carcinoma: The association with treatment efficacy of pemetrexed
-
10.1016/j.lungcan.2011.01.024 21367480 10.1016/j.lungcan.2011.01.024
-
Chen C-Y, Chang Y-L, Shih J-Y, Lin J-W, Chen K-Y, Yang C-H, Yu C-J, Yang P-C (2011) Thymidylate synthase and dihydrofolate reductase expression in non-small cell lung carcinoma: the association with treatment efficacy of pemetrexed. Lung Cancer 74(1):132-138. doi: 10.1016/j.lungcan.2011.01.024
-
(2011)
Lung Cancer
, vol.74
, Issue.1
, pp. 132-138
-
-
Chen, C.-Y.1
Chang, Y.-L.2
Shih, J.-Y.3
Lin, J.-W.4
Chen, K.-Y.5
Yang, C.-H.6
Yu, C.-J.7
Yang, P.-C.8
-
33
-
-
84878973389
-
Thymidylate synthase and ERCC1 as predictive markers in patients with pulmonary adenocarcinoma treated with pemetrexed and cisplatin
-
10.1016/j.lungcan.2013.03.002 23523421 10.1016/j.lungcan.2013.03.002
-
Lee SH, Noh KB, Lee JS, Lee EJ, Min KH, Hur GY, Lee SH, Lee SY, Kim JH, Lee SY, Shin C, Shim JJ, Kim CH, Kang KH, In KH (2013) Thymidylate synthase and ERCC1 as predictive markers in patients with pulmonary adenocarcinoma treated with pemetrexed and cisplatin. Lung Cancer 81(1):102-108. doi: 10.1016/j.lungcan.2013.03.002
-
(2013)
Lung Cancer
, vol.81
, Issue.1
, pp. 102-108
-
-
Lee, S.H.1
Noh, K.B.2
Lee, J.S.3
Lee, E.J.4
Min, K.H.5
Hur, G.Y.6
Lee, S.H.7
Lee, S.Y.8
Kim, J.H.9
Lee, S.Y.10
Shin, C.11
Shim, J.J.12
Kim, C.H.13
Kang, K.H.14
In, K.H.15
-
34
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
10.1056/NEJMoa0810699 19692680 1:CAS:528:DC%2BD1MXhtVygsbfK 10.1056/NEJMoa0810699
-
Mok TS, Wu Y-L, Thongprasert S, Yang C-H, Chu D-T, Saijo N, Sunpaweravong P, Han B, Margono B, Ichinose Y, Nishiwaki Y, Ohe Y, Yang J-J, Chewaskulyong B, Jiang H, Duffield EL, Watkins CL, Armour AA, Fukuoka M (2009) Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 361(10):947-957. doi: 10.1056/NEJMoa0810699
-
(2009)
N Engl J Med
, vol.361
, Issue.10
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.-L.2
Thongprasert, S.3
Yang, C.-H.4
Chu, D.-T.5
Saijo, N.6
Sunpaweravong, P.7
Han, B.8
Margono, B.9
Ichinose, Y.10
Nishiwaki, Y.11
Ohe, Y.12
Yang, J.-J.13
Chewaskulyong, B.14
Jiang, H.15
Duffield, E.L.16
Watkins, C.L.17
Armour, A.A.18
Fukuoka, M.19
-
35
-
-
80054107639
-
Excision repair cross-complementation group 1 (ERCC1) status and lung cancer outcomes: A meta-analysis of published studies and recommendations
-
10.1371/journal.pone.0025164 22022380 1:CAS:528:DC%2BC3MXhsVCju7vN 10.1371/journal.pone.0025164
-
Hubner RA, Riley RD, Billingham LJ, Popat S (2011) Excision repair cross-complementation group 1 (ERCC1) status and lung cancer outcomes: a meta-analysis of published studies and recommendations. PLoS ONE 6(10):e25164. doi: 10.1371/journal.pone.0025164
-
(2011)
PLoS ONE
, vol.6
, Issue.10
, pp. 25164
-
-
Hubner, R.A.1
Riley, R.D.2
Billingham, L.J.3
Popat, S.4
-
36
-
-
33750579074
-
RRM1 modulated in vitro and in vivo efficacy of gemcitabine and platinum in non-small-cell lung cancer
-
DOI 10.1200/JCO.2006.06.1101
-
Bepler G, Kusmartseva I, Sharma S, Gautam A, Cantor A, Sharma A, Simon G (2006) RRM1 modulated in vitro and in vivo efficacy of gemcitabine and platinum in non-small-cell lung cancer. J Clin Oncol Off J Am Soc Clin Oncol 24(29):4731-4737. doi: 10.1200/JCO.2006.06.1101 (Pubitemid 46646245)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.29
, pp. 4731-4737
-
-
Bepler, G.1
Kusmartseva, I.2
Sharma, S.3
Gautam, A.4
Cantor, A.5
Sharma, A.6
Simon, G.7
-
37
-
-
65849467964
-
Correlation between thymidylate synthase protein expression and gene polymorphism with clinicopathological parameters in colorectal carcinoma
-
10.1177/1066896908330480 19147506 1:CAS:528:DC%2BD1MXms1Gmu70%3D 10.1177/1066896908330480
-
Moreira LR, Schenka AA, Latuff Filho P, Nascimento H, Passos Lima CS, Silva Trevisan MA, Vassallo J (2009) Correlation between thymidylate synthase protein expression and gene polymorphism with clinicopathological parameters in colorectal carcinoma. Int J Surg Pathol 17(3):181-186. doi: 10.1177/ 1066896908330480
-
(2009)
Int J Surg Pathol
, vol.17
, Issue.3
, pp. 181-186
-
-
Moreira, L.R.1
Schenka, A.A.2
Latuff Filho, P.3
Nascimento, H.4
Passos Lima, C.S.5
Silva Trevisan, M.A.6
Vassallo, J.7
-
38
-
-
84877648468
-
Prediction of survival benefits from progression-free survival benefits in advanced non-small-cell lung cancer: Evidence from a meta-analysis of 2334 patients from 5 randomised trials
-
doi: 10.1136/bmjopen-2012-001802
-
Laporte S, Squifflet P, Baroux N, Fossella F, Georgoulias V, Pujol J-L, Douillard J-Y, Kudoh S, Pignon J-P, Quinaux E, Buyse M (2013) Prediction of survival benefits from progression-free survival benefits in advanced non-small-cell lung cancer: evidence from a meta-analysis of 2334 patients from 5 randomised trials. BMJ Open 3(3). doi: 10.1136/bmjopen-2012-001802
-
(2013)
BMJ Open
, vol.3
, Issue.3
-
-
Laporte, S.1
Squifflet, P.2
Baroux, N.3
Fossella, F.4
Georgoulias, V.5
Pujol, J.-L.6
Douillard, J.-Y.7
Kudoh, S.8
Pignon, J.-P.9
Quinaux, E.10
Buyse, M.11
-
39
-
-
84876592083
-
A genomic view of mosaicism and human disease
-
10.1038/nrg3424 23594909 1:CAS:528:DC%2BC3sXlvFyqtLg%3D 10.1038/nrg3424
-
Biesecker LG, Spinner NB (2013) A genomic view of mosaicism and human disease. Nat Rev Genet 14(5):307-320. doi: 10.1038/nrg3424
-
(2013)
Nat Rev Genet
, vol.14
, Issue.5
, pp. 307-320
-
-
Biesecker, L.G.1
Spinner, N.B.2
|