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Volumn 22, Issue 8, 2011, Pages 1791-1797

Thymidylate synthase (TS) gene expression in primary lung cancer patients: A large-scale study in Japanese population

Author keywords

Lung cancer; Thymidylate synthase; TS

Indexed keywords

ADULT; AGED; ARTICLE; CANCER STAGING; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMALE; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; JAPANESE; LASER CAPTURE MICRODISSECTION; LUNG ADENOCARCINOMA; LUNG ALVEOLUS EPITHELIUM; LUNG CANCER; LUNG SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; LYMPH NODE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; THYMIDYLATE SYNTHASE GENE; TUMOR CELL; TUMOR GROWTH;

EID: 79960987500     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdq730     Document Type: Article
Times cited : (41)

References (40)
  • 2
    • 0345872083 scopus 로고    scopus 로고
    • Multidisciplinary management of lung cancer
    • Spira A, Ettinger DS. Multidisciplinary management of lung cancer. N Engl J Med 2004; 350: 379-392.
    • (2004) N Engl J Med , vol.350 , pp. 379-392
    • Spira, A.1    Ettinger, D.S.2
  • 3
    • 0034718941 scopus 로고    scopus 로고
    • Non-small-cell lung cancer-stalemate or progress
    • Carney DN, Hansen HH. Non-small-cell lung cancer-stalemate or progress. N Engl J Med 2000; 343: 1261-1262.
    • (2000) N Engl J Med , vol.343 , pp. 1261-1262
    • Carney, D.N.1    Hansen, H.H.2
  • 5
    • 33847276516 scopus 로고    scopus 로고
    • Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and cisplatin plus vinorelbine for advanced non-small-cell lung cancer: Four-Arm Cooporative Study in Japan
    • Ohe Y, Ohashi Y, Kubota K et al. Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and cisplatin plus vinorelbine for advanced non-small-cell lung cancer: Four-Arm Cooporative Study in Japan. Ann Oncol 2007; 18: 317-323.
    • (2007) Ann Oncol , vol.18 , pp. 317-323
    • Ohe, Y.1    Ohashi, Y.2    Kubota, K.3
  • 6
    • 77649104920 scopus 로고    scopus 로고
    • First-line systemic chemotherapy in the treatment of advanced non-small cell lung cancer
    • Goffin J, Lacchetti C, Ellis PM et al. First-line systemic chemotherapy in the treatment of advanced non-small cell lung cancer. J Thorac Oncol 2010; 5: 260-274.
    • (2010) J Thorac Oncol , vol.5 , pp. 260-274
    • Goffin, J.1    Lacchetti, C.2    Ellis, P.M.3
  • 7
    • 33845490014 scopus 로고    scopus 로고
    • Paclitaxel-carboplatin alone or with bevacizumab for non-small cell lung cancer
    • Sandler A, Gray R, Perry MC et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small cell lung cancer. N Engl J Med 2006; 355: 2542-2550.
    • (2006) N Engl J Med , vol.355 , pp. 2542-2550
    • Sandler, A.1    Gray, R.2    Perry, M.C.3
  • 8
    • 62449124416 scopus 로고    scopus 로고
    • Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil
    • Reck M, von Pawel J, Zantloukal P et al. Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil. J Clin Oncol 2009; 27: 1227-1234.
    • (2009) J Clin Oncol , vol.27 , pp. 1227-1234
    • Reck, M.1    von Pawel, J.2    Zantloukal, P.3
  • 9
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated nonsmall-cell lung cancer
    • Shepherd FA, Pereira JR, Ciuleanu T et al. Erlotinib in previously treated nonsmall-cell lung cancer. N Engl J Med 2005; 353: 123-132.
    • (2005) N Engl J Med , vol.353 , pp. 123-132
    • Shepherd, F.A.1    Pereira, J.R.2    Ciuleanu, T.3
  • 10
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Mok TS, Wu YL, Thongprasert S et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009; 361: 947-957.
    • (2009) N Engl J Med , vol.361 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3
  • 11
    • 75249087060 scopus 로고    scopus 로고
    • Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomized phase 3 trial
    • Mistudomi T, Morita S, Yatabe Y et al. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomized phase 3 trial. Lancet Oncol 2010; 11: 121-128.
    • (2010) Lancet Oncol , vol.11 , pp. 121-128
    • Mistudomi, T.1    Morita, S.2    Yatabe, Y.3
  • 12
    • 2442661845 scopus 로고    scopus 로고
    • Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy
    • Hanna N, Shepherd FA, Fossella FV et al. Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy. J Clin Oncol 2004; 22: 1589-1597.
    • (2004) J Clin Oncol , vol.22 , pp. 1589-1597
    • Hanna, N.1    Shepherd, F.A.2    Fossella, F.V.3
  • 13
    • 49049089802 scopus 로고    scopus 로고
    • Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naïve patients with advanced-stage non-small-cell lung cancer
    • Scagliotti GV, Parikh P, von Pawel J et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naïve patients with advanced-stage non-small-cell lung cancer. J Clin Oncol 2008; 26: 3543-3551.
    • (2008) J Clin Oncol , vol.26 , pp. 3543-3551
    • Scagliotti, G.V.1    Parikh, P.2    von Pawel, J.3
  • 14
    • 70350225538 scopus 로고    scopus 로고
    • Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomized, double-blind, phase 3 study
    • Ciuleanu T, Brodowicz T, Zielinski C et al. Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomized, double-blind, phase 3 study. Lancet 2009; 374: 1432-1440.
    • (2009) Lancet , vol.374 , pp. 1432-1440
    • Ciuleanu, T.1    Brodowicz, T.2    Zielinski, C.3
  • 15
    • 0035964611 scopus 로고    scopus 로고
    • Phase II study of S-1, a novel oral fluorouracil, in advanced non-small-cell lung cancer
    • Kawahara M, Furuse K, Segawa Y et al. Phase II study of S-1, a novel oral fluorouracil, in advanced non-small-cell lung cancer. Br J Cancer 2001; 85: 939-943.
    • (2001) Br J Cancer , vol.85 , pp. 939-943
    • Kawahara, M.1    Furuse, K.2    Segawa, Y.3
  • 16
    • 9744222663 scopus 로고    scopus 로고
    • S-1 plus cisplatin combination chemotherapy in patients with advanced non-small cell lung cancer: a multiinstitutional phase II study
    • Ichinose Y, Yoshimori K, Sakai H et al. S-1 plus cisplatin combination chemotherapy in patients with advanced non-small cell lung cancer: a multiinstitutional phase II study. Clin Cancer Res 2005; 10: 7860-7864.
    • (2005) Clin Cancer Res , vol.10 , pp. 7860-7864
    • Ichinose, Y.1    Yoshimori, K.2    Sakai, H.3
  • 17
    • 0030891198 scopus 로고    scopus 로고
    • LY231514, a pyrrolo [2,3-d] pyrimidinebased antifolate that inhibits multiple folate-requiring enzymes
    • Shih C, Chen VJ, Gossetti LS et al. LY231514, a pyrrolo [2,3-d] pyrimidinebased antifolate that inhibits multiple folate-requiring enzymes. Cancer Res 1997; 57: 1116-1123.
    • (1997) Cancer Res , vol.57 , pp. 1116-1123
    • Shih, C.1    Chen, V.J.2    Gossetti, L.S.3
  • 18
    • 0032898580 scopus 로고    scopus 로고
    • Role of thymidylate synthase in the antitumor activity of the multitargeted antifolate, LY231514
    • Shultz RM, Patel VF, Worzalla JF et al. Role of thymidylate synthase in the antitumor activity of the multitargeted antifolate, LY231514. Anticancer Res 1999; 19(1A): 437-443.
    • (1999) Anticancer Res , vol.19 , Issue.1 A , pp. 437-443
    • Shultz, R.M.1    Patel, V.F.2    Worzalla, J.F.3
  • 19
    • 33847745417 scopus 로고    scopus 로고
    • Changes in the status of p53 affect drug sensitivity to thymidylate synthase (TS) inhibitors by altering TS levels
    • Giovannetti E, Backus HH, Wouters D et al. Changes in the status of p53 affect drug sensitivity to thymidylate synthase (TS) inhibitors by altering TS levels. Br J Cancer 2007; 96: 769-775.
    • (2007) Br J Cancer , vol.96 , pp. 769-775
    • Giovannetti, E.1    Backus, H.H.2    Wouters, D.3
  • 20
    • 71849118033 scopus 로고    scopus 로고
    • Significance of thymidylate synthase for resistance to pemetrexed in lung cancer
    • Ozasa H, Oguri T, Uemura T et al. Significance of thymidylate synthase for resistance to pemetrexed in lung cancer. Cancer Sci 2010; 101: 161-166.
    • (2010) Cancer Sci , vol.101 , pp. 161-166
    • Ozasa, H.1    Oguri, T.2    Uemura, T.3
  • 21
    • 32944482800 scopus 로고    scopus 로고
    • A phase II trial of pemetrexed in advanced breast cancer: clinical response and association with molecular target expression
    • Gomez HL, Santillana SL, Vallejos CS et al. A phase II trial of pemetrexed in advanced breast cancer: clinical response and association with molecular target expression. Clin Cancer Res 2006; 12: 832-838.
    • (2006) Clin Cancer Res , vol.12 , pp. 832-838
    • Gomez, H.L.1    Santillana, S.L.2    Vallejos, C.S.3
  • 22
    • 0036217711 scopus 로고    scopus 로고
    • Thymidylate synthase: a critical target for cancer chemotherapy
    • Rose MG, Farrell MP, Schmitz JC. Thymidylate synthase: a critical target for cancer chemotherapy. Clin Colorectal Cancer 2002; 1: 220-229.
    • (2002) Clin Colorectal Cancer , vol.1 , pp. 220-229
    • Rose, M.G.1    Farrell, M.P.2    Schmitz, J.C.3
  • 23
    • 77951894575 scopus 로고    scopus 로고
    • Thymidylate synthase but not excision repair cross-complementation group 1 tumor expression predicts outcome in patients with malignant pleural mesothelioma treated with pemetrexed-based chemotherapy
    • Righi L, Papotti MG, Ceppi P et al. Thymidylate synthase but not excision repair cross-complementation group 1 tumor expression predicts outcome in patients with malignant pleural mesothelioma treated with pemetrexed-based chemotherapy. J Clin Oncol 2010; 28: 1534-1539.
    • (2010) J Clin Oncol , vol.28 , pp. 1534-1539
    • Righi, L.1    Papotti, M.G.2    Ceppi, P.3
  • 24
    • 58949083363 scopus 로고    scopus 로고
    • Pemetrexed in relapsed small-cell lung cancer and the impact of shortened vitamin supplementation lead-in time: results of a phase II trial
    • Socinski MA, Raju RN, Neubauer N et al. Pemetrexed in relapsed small-cell lung cancer and the impact of shortened vitamin supplementation lead-in time: results of a phase II trial. J Thorac Oncol 2008; 3: 1308-1316.
    • (2008) J Thorac Oncol , vol.3 , pp. 1308-1316
    • Socinski, M.A.1    Raju, R.N.2    Neubauer, N.3
  • 25
    • 61549083739 scopus 로고    scopus 로고
    • Pemetrexed in second line and beyond small cell lung cancer: a Hoosier Oncology Group phase II study
    • Jalal S, Ansari R, Govindan R et al. Pemetrexed in second line and beyond small cell lung cancer: a Hoosier Oncology Group phase II study. J Thorac Oncol 2009; 4: 93-96.
    • (2009) J Thorac Oncol , vol.4 , pp. 93-96
    • Jalal, S.1    Ansari, R.2    Govindan, R.3
  • 26
    • 57649092721 scopus 로고    scopus 로고
    • A prospective phase II study: highdose pemetrexed as second-line chemotherapy for small-cell lung cancer
    • Gronberg BH, Bremners RM, Asaebo U et al. A prospective phase II study: highdose pemetrexed as second-line chemotherapy for small-cell lung cancer. Lung Cancer 2009; 63: 88-93.
    • (2009) Lung Cancer , vol.63 , pp. 88-93
    • Gronberg, B.H.1    Bremners, R.M.2    Asaebo, U.3
  • 27
    • 64049115311 scopus 로고    scopus 로고
    • The differential efficacy of pemetrexed according to NSCLC histology: a review of two Phase III studies
    • Scagliotti G, Hanna N, Fossella F et al. The differential efficacy of pemetrexed according to NSCLC histology: a review of two Phase III studies. Oncologist 2009; 14: 253-263.
    • (2009) Oncologist , vol.14 , pp. 253-263
    • Scagliotti, G.1    Hanna, N.2    Fossella, F.3
  • 28
    • 77949624488 scopus 로고    scopus 로고
    • Prognostic and predictive factors in a randomized phase III trial comparing cisplatin-pemetrexed versus cisplatingemcitabine in advanced non-small-cell lung cancer
    • Syrigos KN, Vansteenkiste J, Parikh P et al. Prognostic and predictive factors in a randomized phase III trial comparing cisplatin-pemetrexed versus cisplatingemcitabine in advanced non-small-cell lung cancer. Ann Oncol 2010; 21: 556-561.
    • (2010) Ann Oncol , vol.21 , pp. 556-561
    • Syrigos, K.N.1    Vansteenkiste, J.2    Parikh, P.3
  • 29
    • 33749587054 scopus 로고    scopus 로고
    • Squamous cell carcinoma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase
    • Ceppi P, Volante M, Saviozzi S et al. Squamous cell carcinoma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase. Cancer 2006; 107: 1589-1596.
    • (2006) Cancer , vol.107 , pp. 1589-1596
    • Ceppi, P.1    Volante, M.2    Saviozzi, S.3
  • 30
    • 73349084270 scopus 로고    scopus 로고
    • Differential thymidylate synthase expression in different variants of large-cell carcinoma of the lung
    • Monica V, Scagliotti GV, Ceppi P et al. Differential thymidylate synthase expression in different variants of large-cell carcinoma of the lung. Clin Cancer Res 2009; 15: 7547-7552.
    • (2009) Clin Cancer Res , vol.15 , pp. 7547-7552
    • Monica, V.1    Scagliotti, G.V.2    Ceppi, P.3
  • 31
    • 9344248389 scopus 로고    scopus 로고
    • Antitumor activity of 1M tegafur-0.4M 5-chloro-2,4-hydroxypyridine-1M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats.
    • Shirasaka T, Nakano K, Takechi T et al. Antitumor activity of 1M tegafur-0.4M 5-chloro-2,4-hydroxypyridine-1M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats. Cancer Res 1996; 56: 2602-2606.
    • (1996) Cancer Res , vol.56 , pp. 2602-2606
    • Shirasaka, T.1    Nakano, K.2    Takechi, T.3
  • 33
    • 24644514458 scopus 로고    scopus 로고
    • Meta-analysis of postoperative adjuvant chemotherapy with tegafur-uracil in non-small-cell lung cancer
    • Hamada C, Tanaka F, Ohta M et al. Meta-analysis of postoperative adjuvant chemotherapy with tegafur-uracil in non-small-cell lung cancer. J Clin Oncol 2005; 23: 4999-5006.
    • (2005) J Clin Oncol , vol.23 , pp. 4999-5006
    • Hamada, C.1    Tanaka, F.2    Ohta, M.3
  • 34
    • 18044373030 scopus 로고    scopus 로고
    • Clinical application of biological markers for treatment of resectable non-small-cell lung cancer
    • Huang C, Liu D, Masuya D et al. Clinical application of biological markers for treatment of resectable non-small-cell lung cancer. Br J Cancer 2005; 92: 1231-1239.
    • (2005) Br J Cancer , vol.92 , pp. 1231-1239
    • Huang, C.1    Liu, D.2    Masuya, D.3
  • 35
    • 58149396155 scopus 로고    scopus 로고
    • Comparison of 5-fluorouracil-related gene expression levels between adenocarcinoma and squamous cell carcinoma of the lung
    • Ishihama H, Chida M, Araki O et al. Comparison of 5-fluorouracil-related gene expression levels between adenocarcinoma and squamous cell carcinoma of the lung. Jpn J Clin Oncol 2009; 39: 33-36.
    • (2009) Jpn J Clin Oncol , vol.39 , pp. 33-36
    • Ishihama, H.1    Chida, M.2    Araki, O.3
  • 36
    • 65449177682 scopus 로고    scopus 로고
    • Thymidylate synthase, dihydropyrimidine dehydrogenase, orotate phosphoribosyltransferase mRNA and protein expression levels in solid tumors in large scale population analysis
    • Fukui Y, Oka T, Nagayama S et al. Thymidylate synthase, dihydropyrimidine dehydrogenase, orotate phosphoribosyltransferase mRNA and protein expression levels in solid tumors in large scale population analysis. Int J Mol Med 2008; 22: 709-716.
    • (2008) Int J Mol Med , vol.22 , pp. 709-716
    • Fukui, Y.1    Oka, T.2    Nagayama, S.3
  • 37
    • 0032761514 scopus 로고    scopus 로고
    • Expression of thymidylate synthase in human non-small cell lung cancer
    • Otake Y, Tanaka F, Yanagihara K et al. Expression of thymidylate synthase in human non-small cell lung cancer. Jpn J Cancer Res 1999; 90: 1248-1253.
    • (1999) Jpn J Cancer Res , vol.90 , pp. 1248-1253
    • Otake, Y.1    Tanaka, F.2    Yanagihara, K.3
  • 38
    • 0036164591 scopus 로고    scopus 로고
    • Prognostic value of thymidylate synthase expression in patients with p-stage I adenocarcinoma of the lung
    • Nakagawa T, Tanaka F, Otake Y et al. Prognostic value of thymidylate synthase expression in patients with p-stage I adenocarcinoma of the lung. Lung Cancer 2002; 35: 165-170.
    • (2002) Lung Cancer , vol.35 , pp. 165-170
    • Nakagawa, T.1    Tanaka, F.2    Otake, Y.3
  • 39
    • 1642534412 scopus 로고    scopus 로고
    • Expression of thymidylate synthase is correlated with proliferative activity in non-small cell lung cancer
    • Nakagawa T, Otake Y, Yanagihara K et al. Expression of thymidylate synthase is correlated with proliferative activity in non-small cell lung cancer. Lung Cancer 2004; 43: 145-149.
    • (2004) Lung Cancer , vol.43 , pp. 145-149
    • Nakagawa, T.1    Otake, Y.2    Yanagihara, K.3
  • 40
    • 77955833044 scopus 로고    scopus 로고
    • Pooled analysis of S-1 trials in nonsmall cell lung cancer according to histological type
    • Yamamoto N, Yamanaka T, Ichinose Y et al. Pooled analysis of S-1 trials in nonsmall cell lung cancer according to histological type. Anticancer Res 2010; 30: 2985-2990.
    • (2010) Anticancer Res , vol.30 , pp. 2985-2990
    • Yamamoto, N.1    Yamanaka, T.2    Ichinose, Y.3


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