Vasospasm of atherosclerotic coronary arteries precipitates acute ischemic myocardial damage in myocardial infarction-prone strain of the watanabe heritable hyperlipidemic rabbits

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 33, Issue 11, 2013, Pages 2518-2523

  Shiomi, Masashi ^a   Ishida, Tatsuro ^a   Kobayashi, Tsutomu ^a   Nitta, Norihisa ^b   Sonoda, Akinaga ^b   Yamada, Satoshi ^a   Koike, Tomonari ^a   Kuniyoshi, Nobue ^a   Murata, Kiyoshi ^b   Hirata, Ken Ichi ^a   Ito, Takashi ^a   Libby, Peter ^c  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

cardiovascular diseases; coronary atherosclerosis; coronary vasospasm; ischemia, myocardium; models, animal

Indexed keywords

ERGOMETRINE MALEATE; FATTY ACID BINDING PROTEIN; GLYCERYL TRINITRATE; MYOGLOBIN; NORADRENALIN; TROPONIN I;

ANGIOCARDIOGRAPHY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROTIC PLAQUE; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY SPASM; CORONARY ARTERY THROMBOSIS; ELECTROCARDIOGRAM; ENDOTHELIUM CELL; EXPERIMENTAL RABBIT; HEART INFARCTION; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE WALL MOTION; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART VENTRICLE FUNCTION; HYPERLIPIDEMIA; MACROPHAGE; MICROTHROMBUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; ST SEGMENT DEPRESSION; ST SEGMENT ELEVATION; T WAVE INVERSION; THROMBUS;

CARDIOVASCULAR DISEASES; CORONARY ATHEROSCLEROSIS; CORONARY VASOSPASM; ISCHEMIA, MYOCARDIUM; MODELS, ANIMAL;

ACUTE CORONARY SYNDROME; ANIMALS; CORONARY ARTERY DISEASE; CORONARY VASOSPASM; CORONARY VESSELS; DISEASE MODELS, ANIMAL; ERGONOVINE; HYPERLIPIDEMIAS; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; NOREPINEPHRINE; OXYTOCICS; RABBITS; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

EID: 84887125204     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.113.301303     Document Type: Article

References (27)

1. Libby P. Mechanisms of acute coronary syndromes and their implications for therapy. N Engl J Med. 2013;368:2004-2013.
2. Libby P, Okamoto Y, Rocha VZ, Folco E. Infammation in atherosclerosis: transition from theory to practice. Circ J. 2010;74:213-220.
3. Horton DB, Libby P, Schonbeck U. Ligation of CD40 on vascular smooth muscle cells mediates loss of interstitial collagen via matrix metallopro-teinase activity. Ann N Y Acad Sci. 2001;947:329-336.
4. Zeibig S, Li Z, Wagner S, Holthoff HP, Ungerer M, Bültmann A, Uhland K, Vogelmann J, Simmet T, Gawaz M, Münch G. Effect of the oxLDL binding protein Fc-CD68 on plaque extension and vulnerability in atherosclerosis. Circ Res. 2011;108:695-703.
5. Virmani R, Kolodgie FD, Burke AP, Finn AV, Gold HK, Tulenko TN, Wrenn SP, Narula J. Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage. Arterioscler Thromb Vasc Biol. 2005;25:2054-2061.
6. Virmani R, Kolodgie FD, Burke AP, Farb A, Schwartz SM. Lessons from sudden coronary death: a comprehensive morphological classifca-tion scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol. 2000;20:1262-1275.
7. Cheruvu PK, Finn AV, Gardner C, Caplan J, Goldstein J, Stone GW, Virmani R, Muller JE. Frequency and distribution of thin-cap fbroather-oma and ruptured plaques in human coronary arteries: a pathologic study. J Am Coll Cardiol. 2007;50:940-949.
8. Falk E, Nakano M, Bentzon JF, Finn AV, Virmani R. Update on acute coronary syndromes: the pathologists' view. Eur Heart J. 2013;34: 719-728.
9. Sadat U, Teng Z, Gillard JH. Biomechanical structural stresses of atherosclerotic plaques. Expert Rev Cardiovasc Ther. 2010;8:1469-1481.
10. Maseri A, Beltrame JF, Shimokawa H. Role of coronary vasoconstriction in ischemic heart disease and search for novel therapeutic targets. Circ J. 2009;73:394-403.
11. Schwartz SM, Galis ZS, Rosenfeld ME, Falk E. Plaque rupture in humans and mice. Arterioscler Thromb Vasc Biol. 2007;27:705-713.
12. Bentzon JF, Falk E. Atherosclerotic lesions in mouse and man: is it the same disease? Curr Opin Lipidol. 2010;21:434-440.
13. Johnson J, Carson K, Williams H, Karanam S, Newby A, Angelini G, George S, Jackson C. Plaque rupture after short periods of fat feeding in the apolipoprotein E-knockout mouse: model characterization and effects of pravastatin treatment. Circulation. 2005;111:1422-1430.
14. Reimers GJ, Jackson CL, Rickards J, Chan PY, Cohn JS, Rye KA, Barter PJ, Rodgers KJ. Inhibition of rupture of established atherosclerotic plaques by treatment with apolipoprotein A-I. Cardiovasc Res. 2011;91:37-44.
15. Braun A, Trigatti BL, Post MJ, Sato K, Simons M, Edelberg JM, Rosenberg RD, Schrenzel M, Krieger M. Loss of SR-BI expression leads to the early onset of occlusive atherosclerotic coronary artery disease, spontaneous myocardial infarctions, severe cardiac dysfunction, and premature death in apolipoprotein E-defcient mice. Circ Res. 2002;90:270-276.
16. Shiomi M, Ito T, Tsukada T, Yata T, Ueda M. Cell compositions of coronary and aortic atherosclerotic lesions in WHHL rabbits differ. An immu-nohistochemical study. Arterioscler Thromb. 1994;14:931-937.
17. Caligiuri G, Levy B, Pernow J, Thorén P, Hansson GK. Myocardial infarction mediated by endothelin receptor signaling in hypercholesterolemic mice. Proc Natl Acad Sci USA. 1999;96:6920-6924.
18. Nagasawa K, Tomoike H, Hayashi Y, Yamada A, Yamamoto T, Nakamura M. Intramural hemorrhage and endothelial changes in atherosclerotic coronary artery after repetitive episodes of spasm in X-ray-irradiated hyper-cholesterolemic pigs. Circ Res. 1989;65:272-282.
19. Kuga T, Tagawa H, Tomoike H, Mitsuoka W, Egashira S, Ohara Y, Takeshita A, Nakamura M. Role of coronary artery spasm in progression of organic coronary stenosis and acute myocardial infarction in a swine model. Importance of mode of onset and duration of coronary artery spasm. Circulation. 1993;87:573-582.
20. Nakamura M, Abe S. Arteriosclerotic lesions of the distal small coronary artery in cholesterol-fed rabbits differ from those in watanabe heritable-hyperlipidemic rabbits. Ann N Y Acad Sci. 1997;811:420-423.
21. Phinikaridou A, Hallock KJ, Qiao Y, Hamilton JA. A robust rabbit model of human atherosclerosis and atherothrombosis. J Lipid Res. 2009;50:787-797.
22. Shiomi M, Ito T, Yamada S, Kawashima S, Fan J. Development of an animal model for spontaneous myocardial infarction (WHHLMI rabbit). Arterioscler Thromb Vasc Biol. 2003;23:1239-1244.
23. Tanzawa K, Shimada Y, Kuroda M, Tsujita Y, Arai M, Watanabe H. WHHL-rabbit: a low density lipoprotein receptor-defcient animal model for familial hypercholesterolemia. FEBS Lett. 1980;118:81-84.
24. Yamamoto T, Bishop RW, Brown MS, Goldstein JL, Russell DW. Deletion in cysteine-rich region of LDL receptor impedes transport to cell surface in WHHL rabbit. Science. 1986;232:1230-1237.
25. Shiomi M, Ito T. The Watanabe heritable hyperlipidemic (WHHL) rabbit, its characteristics and history of development: a tribute to the late Dr. Yoshio Watanabe. Atherosclerosis. 2009;207:1-7.
26. Shiomi M, Fan J. Unstable coronary plaques and cardiac events in myo-cardial infarction-prone Watanabe heritable hyperlipidemic rabbits: questions and quandaries. Curr Opin Lipidol. 2008;19:631-636.
27. Lendrum AC, Fraser DS, Slidders W, Henderson R. Studies on the character and staining of fbrin. J Clin Pathol. 1962;15:401-413.