Bovine lactoferricin-induced anti-inflammation is, in part, via up-regulation of interleukin-11 by secondary activation of STAT3 in human articular cartilage

Journal of Biological Chemistry

Volumn 288, Issue 44, 2013, Pages 31655-31669

  Yan, Dongyao ^a   Kc, Ranjan ^a   Chen, Di ^a   Xiao, Guozhi ^a   Im, Hee Jeong ^a,b  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b University of Illinois at Chicago   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICULAR CHONDROCYTES; BOVINE LACTOFERRICIN; HUMAN ARTICULAR CARTILAGE; INFLAMMATORY PROCESS; PROTEOGLYCAN DEPLETION; RECEPTOR EXPRESSION; SECONDARY ACTIVATIONS; TWO-STEP MECHANISMS;

BODY FLUIDS; GENES; MAMMALS;

CARTILAGE;

BOVINE LACTOFERRICIN; HEPARAN SULFATE; INTERLEUKIN 11; INTERLEUKIN 8; LACTOFERRICIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN C FOS; STAT3 PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR JUND; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL ISOLATION; CELL PROTECTION; CELL SURFACE; CONTROLLED STUDY; DOWN REGULATION; DRUG BINDING; EX VIVO STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IL 11 GENE; IMMUNOBLOTTING; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION;

ARTICULAR CARTILAGE; CHONDROCYTES; GENE REGULATION; INTERLEUKIN; OSTEOARTHRITIS; SIGNAL TRANSDUCTION;

ADULT; AGED; ANIMALS; ANTI-INFLAMMATORY AGENTS; CARTILAGE, ARTICULAR; CATTLE; CHONDROCYTES; FEMALE; HUMANS; INTERLEUKIN-11; LACTOFERRIN; MALE; MAP KINASE SIGNALING SYSTEM; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; OSTEOARTHRITIS; STAT3 TRANSCRIPTION FACTOR; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TRANSCRIPTION FACTOR AP-1; UP-REGULATION;

EID: 84887108432     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.440420     Document Type: Article

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