메뉴 건너뛰기




Volumn 141, Issue 3, 2013, Pages 375-384

Metastasis tumor-associated protein 2 enhances metastatic behavior and is associated with poor outcomes in estrogen receptor-negative breast cancer

Author keywords

Breast cancer; Cytoskeleton; Metastasis; MTA2; Rho

Indexed keywords

PROTEIN MTA2; RHO FACTOR; RHO KINASE INHIBITOR; TUMOR MARKER; TUMOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84887056650     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-013-2709-5     Document Type: Article
Times cited : (41)

References (50)
  • 1
    • 0025083071 scopus 로고
    • Critical factors in the biology of human cancer metastasis: Twenty-eighth G.H.A. Clowes memorial award lecture
    • 1698118 1:STN:280:DyaK3czotFKrsA%3D%3D
    • Fidler IJ (1990) Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture. Cancer Res 50(19):6130-6138
    • (1990) Cancer Res , vol.50 , Issue.19 , pp. 6130-6138
    • Fidler, I.J.1
  • 2
    • 40149091965 scopus 로고    scopus 로고
    • Metastasis suppressors genes in cancer
    • 10.1016/j.biocel.2007.12.016 18280770 1:CAS:528:DC%2BD1cXjtVekur8%3D 10.1016/j.biocel.2007.12.016
    • Stafford LJ, Vaidya KS, Welch DR (2008) Metastasis suppressors genes in cancer. Int J Biochem Cell Biol 40(5):874-891. doi: 10.1016/j.biocel.2007.12.016
    • (2008) Int J Biochem Cell Biol , vol.40 , Issue.5 , pp. 874-891
    • Stafford, L.J.1    Vaidya, K.S.2    Welch, D.R.3
  • 3
    • 1642304545 scopus 로고    scopus 로고
    • Altered Rho GTPase signaling pathways in breast cancer cells
    • 10.1023/B:BREA.0000018422.02237.f9 14999153 1:CAS:528: DC%2BD2cXhslGjtbY%3D 10.1023/B:BREA.0000018422.02237.f9
    • Burbelo P, Wellstein A, Pestell RG (2004) Altered Rho GTPase signaling pathways in breast cancer cells. Breast Cancer Res Treat 84(1):43-48. doi: 10.1023/B:BREA.0000018422.02237.f9
    • (2004) Breast Cancer Res Treat , vol.84 , Issue.1 , pp. 43-48
    • Burbelo, P.1    Wellstein, A.2    Pestell, R.G.3
  • 4
    • 24344486013 scopus 로고    scopus 로고
    • RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis
    • 10.1101/gad.1310805 16107613 1:CAS:528:DC%2BD2MXhtVSlurjL 10.1101/gad.1310805
    • Hakem A, Sanchez-Sweatman O, You-Ten A, Duncan G, Wakeham A, Khokha R et al (2005) RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis. Genes Dev 19(17):1974-1979. doi: 10.1101/gad.1310805
    • (2005) Genes Dev , vol.19 , Issue.17 , pp. 1974-1979
    • Hakem, A.1    Sanchez-Sweatman, O.2    You-Ten, A.3    Duncan, G.4    Wakeham, A.5    Khokha, R.6
  • 5
    • 0034981657 scopus 로고    scopus 로고
    • Ras and Rho protein induction of motility and invasion in T47D breast adenocarcinoma cells
    • 11400341 1:CAS:528:DC%2BD3MXltV2nurk%3D 10.1016/S0076-6879(01)33061-6
    • Keely PJ (2001) Ras and Rho protein induction of motility and invasion in T47D breast adenocarcinoma cells. Methods Enzymol 333:256-266
    • (2001) Methods Enzymol , vol.333 , pp. 256-266
    • Keely, P.J.1
  • 6
    • 38449123547 scopus 로고    scopus 로고
    • Role of Rho GTPases in breast cancer
    • 17981586 1:CAS:528:DC%2BD1cXhs1ChtL0%3D 10.2741/2718
    • Tang Y, Olufemi L, Wang MT, Nie D (2008) Role of Rho GTPases in breast cancer. Front Biosci 13:759-776
    • (2008) Front Biosci , vol.13 , pp. 759-776
    • Tang, Y.1    Olufemi, L.2    Wang, M.T.3    Nie, D.4
  • 7
    • 0242552447 scopus 로고    scopus 로고
    • Emerging roles of MTA family members in human cancers
    • 14613024 1:CAS:528:DC%2BD3sXhtVSjtrrO 10.1053/j.seminoncol.2003.08.005
    • Kumar R, Wang RA, Bagheri-Yarmand R (2003) Emerging roles of MTA family members in human cancers. Semin Oncol 30(5 Suppl 16):30-37
    • (2003) Semin Oncol , vol.30 , Issue.5 SUPPL. 16 , pp. 30-37
    • Kumar, R.1    Wang, R.A.2    Bagheri-Yarmand, R.3
  • 8
    • 0037221370 scopus 로고    scopus 로고
    • Tumor metastasis-associated human MTA1 gene and its MTA1 protein product: Role in epithelial cancer cell invasion, proliferation and nuclear regulation
    • 12650603 1:CAS:528:DC%2BD3sXhsVWitLk%3D 10.1023/A:1022534217769
    • Nicolson GL, Nawa A, Toh Y, Taniguchi S, Nishimori K, Moustafa A (2003) Tumor metastasis-associated human MTA1 gene and its MTA1 protein product: role in epithelial cancer cell invasion, proliferation and nuclear regulation. Clin Exp Metastasis 20(1):19-24
    • (2003) Clin Exp Metastasis , vol.20 , Issue.1 , pp. 19-24
    • Nicolson, G.L.1    Nawa, A.2    Toh, Y.3    Taniguchi, S.4    Nishimori, K.5    Moustafa, A.6
  • 9
    • 34547656093 scopus 로고    scopus 로고
    • MTA family of transcriptional metaregulators in mammary gland morphogenesis and breast cancer
    • 10.1007/s10911-007-9043-7 17549610 10.1007/s10911-007-9043-7
    • Singh RR, Kumar R (2007) MTA family of transcriptional metaregulators in mammary gland morphogenesis and breast cancer. J Mammary Gland Biol Neoplasia 12(2-3):115-125. doi: 10.1007/s10911-007-9043-7
    • (2007) J Mammary Gland Biol Neoplasia , vol.12 , Issue.2-3 , pp. 115-125
    • Singh, R.R.1    Kumar, R.2
  • 10
    • 61449111811 scopus 로고    scopus 로고
    • The role of the MTA family and their encoded proteins in human cancers: Molecular functions and clinical implications
    • 10.1007/s10585-008-9233-8 19116762 1:CAS:528:DC%2BD1MXitlaisLk%3D 10.1007/s10585-008-9233-8
    • Toh Y, Nicolson GL (2009) The role of the MTA family and their encoded proteins in human cancers: molecular functions and clinical implications. Clin Exp Metastasis 26(3):215-227. doi: 10.1007/s10585-008-9233-8
    • (2009) Clin Exp Metastasis , vol.26 , Issue.3 , pp. 215-227
    • Toh, Y.1    Nicolson, G.L.2
  • 11
    • 33645071569 scopus 로고    scopus 로고
    • Metastasis tumor antigen family proteins during breast cancer progression and metastasis in a reliable mouse model for human breast cancer
    • 10.1158/1078-0432.CCR-05-1519 16533771 1:CAS:528:DC%2BD28XitVGmsrc%3D 10.1158/1078-0432.CCR-05-1519
    • Zhang H, Stephens LC, Kumar R (2006) Metastasis tumor antigen family proteins during breast cancer progression and metastasis in a reliable mouse model for human breast cancer. Clin Cancer Res 12(5):1479-1486. doi: 10.1158/1078-0432.CCR-05-1519
    • (2006) Clin Cancer Res , vol.12 , Issue.5 , pp. 1479-1486
    • Zhang, H.1    Stephens, L.C.2    Kumar, R.3
  • 12
    • 33747846908 scopus 로고    scopus 로고
    • Metastasis-associated protein 2 is a repressor of estrogen receptor alpha whose overexpression leads to estrogen-independent growth of human breast cancer cells
    • 10.1210/me.2005-0063 16645043 1:CAS:528:DC%2BD28Xpt1Cqurw%3D 10.1210/me.2005-0063
    • Cui Y, Niu A, Pestell R, Kumar R, Curran EM, Liu Y et al (2006) Metastasis-associated protein 2 is a repressor of estrogen receptor alpha whose overexpression leads to estrogen-independent growth of human breast cancer cells. Mol Endocrinol 20(9):2020-2035. doi: 10.1210/me.2005-0063
    • (2006) Mol Endocrinol , vol.20 , Issue.9 , pp. 2020-2035
    • Cui, Y.1    Niu, A.2    Pestell, R.3    Kumar, R.4    Curran, E.M.5    Liu, Y.6
  • 13
    • 79651474948 scopus 로고    scopus 로고
    • The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis
    • 10.1038/cr.2010.118 20714342 1:CAS:528:DC%2BC3MXhsVOmu7g%3D 10.1038/cr.2010.118
    • Fu J, Qin L, He T, Qin J, Hong J, Wong J et al (2011) The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis. Cell Res 21(2):275-289. doi: 10.1038/cr.2010.118
    • (2011) Cell Res , vol.21 , Issue.2 , pp. 275-289
    • Fu, J.1    Qin, L.2    He, T.3    Qin, J.4    Hong, J.5    Wong, J.6
  • 14
    • 0029029343 scopus 로고
    • Analysis of the complete sequence of the novel metastasis-associated candidate gene, MTA1, differentially expressed in mammary adenocarcinoma and breast cancer cell lines
    • 7607577 1:CAS:528:DyaK2MXmvFWqsr4%3D 10.1016/0378-1119(94)00410-T
    • Toh Y, Pencil SD, Nicolson GL (1995) Analysis of the complete sequence of the novel metastasis-associated candidate gene, MTA1, differentially expressed in mammary adenocarcinoma and breast cancer cell lines. Gene 159(1):97-104
    • (1995) Gene , vol.159 , Issue.1 , pp. 97-104
    • Toh, Y.1    Pencil, S.D.2    Nicolson, G.L.3
  • 15
    • 0027978984 scopus 로고
    • A novel candidate metastasis-associated gene, MTA1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. CDNA cloning, expression, and protein analyses
    • 8083195 1:CAS:528:DyaK2MXnsF2ntw%3D%3D
    • Toh Y, Pencil SD, Nicolson GL (1994) A novel candidate metastasis-associated gene, MTA1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression, and protein analyses. J Biol Chem 269(37):22958-22963
    • (1994) J Biol Chem , vol.269 , Issue.37 , pp. 22958-22963
    • Toh, Y.1    Pencil, S.D.2    Nicolson, G.L.3
  • 16
    • 0037453706 scopus 로고    scopus 로고
    • MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer
    • 12705869 1:CAS:528:DC%2BD3sXjtlOqsL8%3D 10.1016/S0092-8674(03)00234-4
    • Fujita N, Jaye DL, Kajita M, Geigerman C, Moreno CS, Wade PA (2003) MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer. Cell 113(2):207-219
    • (2003) Cell , vol.113 , Issue.2 , pp. 207-219
    • Fujita, N.1    Jaye, D.L.2    Kajita, M.3    Geigerman, C.4    Moreno, C.S.5    Wade, P.A.6
  • 17
    • 79953853847 scopus 로고    scopus 로고
    • Loss of Rho GDIα and resistance to tamoxifen via effects on estrogen receptor α
    • 10.1093/jnci/djr058 21447808 1:CAS:528:DC%2BC3MXksFKjur8%3D 10.1093/jnci/djr058
    • Barone I, Brusco L, Gu G, Selever J, Beyer A, Covington KR et al (2011) Loss of Rho GDIα and resistance to tamoxifen via effects on estrogen receptor α. J Natl Cancer Inst 103(7):538-552. doi: 10.1093/jnci/djr058
    • (2011) J Natl Cancer Inst , vol.103 , Issue.7 , pp. 538-552
    • Barone, I.1    Brusco, L.2    Gu, G.3    Selever, J.4    Beyer, A.5    Covington, K.R.6
  • 18
    • 2442507000 scopus 로고    scopus 로고
    • Affordable image analysis using NIH Image/ImageJ
    • 15105580 1:STN:280:DC%2BD2c3gslCktA%3D%3D
    • Girish V, Vijayalakshmi A (2004) Affordable image analysis using NIH Image/ImageJ. Indian J Cancer 41(1):47
    • (2004) Indian J Cancer , vol.41 , Issue.1 , pp. 47
    • Girish, V.1    Vijayalakshmi, A.2
  • 19
    • 77951557127 scopus 로고    scopus 로고
    • Phosphorylation of the mutant K303R estrogen receptor alpha at serine 305 affects aromatase inhibitor sensitivity
    • 10.1038/onc.2009.520 20101208 1:CAS:528:DC%2BC3cXltVGhur4%3D 10.1038/onc.2009.520
    • Barone I, Iacopetta D, Covington KR, Cui Y, Tsimelzon A, Beyer A et al (2010) Phosphorylation of the mutant K303R estrogen receptor alpha at serine 305 affects aromatase inhibitor sensitivity. Oncogene 29(16):2404-2414. doi: 10.1038/onc.2009.520
    • (2010) Oncogene , vol.29 , Issue.16 , pp. 2404-2414
    • Barone, I.1    Iacopetta, D.2    Covington, K.R.3    Cui, Y.4    Tsimelzon, A.5    Beyer, A.6
  • 20
    • 1642377561 scopus 로고    scopus 로고
    • ONCOMINE: A cancer microarray database and integrated data-mining platform
    • 15068665 1:CAS:528:DC%2BD2cXjslSgtrY%3D
    • Rhodes DR, Yu J, Shanker K, Deshpande N, Varambally R, Ghosh D et al (2004) ONCOMINE: a cancer microarray database and integrated data-mining platform. Neoplasia 6(1):1-6
    • (2004) Neoplasia , vol.6 , Issue.1 , pp. 1-6
    • Rhodes, D.R.1    Yu, J.2    Shanker, K.3    Deshpande, N.4    Varambally, R.5    Ghosh, D.6
  • 22
    • 0142121516 scopus 로고    scopus 로고
    • Exploration, normalization, and summaries of high density oligonucleotide array probe level data
    • 10.1093/biostatistics/4.2.249 12925520 10.1093/biostatistics/4.2.249
    • Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U et al (2003) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4(2):249-264. doi: 10.1093/biostatistics/4.2.249
    • (2003) Biostatistics , vol.4 , Issue.2 , pp. 249-264
    • Irizarry, R.A.1    Hobbs, B.2    Collin, F.3    Beazer-Barclay, Y.D.4    Antonellis, K.J.5    Scherf, U.6
  • 23
    • 84887095068 scopus 로고    scopus 로고
    • The Red-R framework for integrated discovery
    • Accessed 14 Dec 2011
    • Covington KR, Parikh A (2011) The Red-R framework for integrated discovery. Red-R J. http://code.google.com/p/r-orange/. Accessed 14 Dec 2011
    • (2011) Red-R J
    • Covington, K.R.1    Parikh, A.2
  • 24
    • 13844310310 scopus 로고    scopus 로고
    • Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer
    • 10.1016/S0140-6736(05)17947-1 15721472 1:CAS:528:DC%2BD2MXhsVOitLk%3D
    • Wang Y, Klijn JGM, Zhang Y, Sieuwerts AM, Look MP, Yang F et al (2005) Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. Lancet 365(9460):671-679. doi: 10.1016/S0140-6736(05) 17947-1
    • (2005) Lancet , vol.365 , Issue.9460 , pp. 671-679
    • Wang, Y.1    Klijn, J.G.M.2    Zhang, Y.3    Sieuwerts, A.M.4    Look, M.P.5    Yang, F.6
  • 25
    • 79958728723 scopus 로고    scopus 로고
    • A gene expression signature identifies two prognostic subgroups of basal breast cancer
    • 10.1007/s10549-010-0897-9 20490655 1:CAS:528:DC%2BC3MXjtFSrsbY%3D 10.1007/s10549-010-0897-9
    • Sabatier R, Finetti P, Cervera N, Lambaudie E, Esterni B, Mamessier E et al (2011) A gene expression signature identifies two prognostic subgroups of basal breast cancer. Breast Cancer Res Treat 126(2):407-420. doi: 10.1007/s10549-010-0897-9
    • (2011) Breast Cancer Res Treat , vol.126 , Issue.2 , pp. 407-420
    • Sabatier, R.1    Finetti, P.2    Cervera, N.3    Lambaudie, E.4    Esterni, B.5    Mamessier, E.6
  • 26
    • 33846064113 scopus 로고    scopus 로고
    • NCBI GEO: Mining tens of millions of expression profiles-database and tools update
    • 10.1093/nar/gkl887 17099226 1:CAS:528:DC%2BD2sXivFKjug%3D%3D 10.1093/nar/gkl887
    • Barrett T, Troup DB, Wilhite SE, Ledoux P, Rudnev D, Evangelista C et al (2007) NCBI GEO: mining tens of millions of expression profiles-database and tools update. Nucleic Acids Res 35(Database issue):D760-D765. doi: 10.1093/nar/gkl887
    • (2007) Nucleic Acids Res , vol.35 , Issue.DATABASE ISSUE
    • Barrett, T.1    Troup, D.B.2    Wilhite, S.E.3    Ledoux, P.4    Rudnev, D.5    Evangelista, C.6
  • 27
    • 0038005018 scopus 로고    scopus 로고
    • DAVID: Database for annotation, visualization, and integrated discovery
    • 12734009 10.1186/gb-2003-4-5-p3
    • Dennis G, Sherman BT, Hosack DA, Yang J, Gao W, Lane HC et al (2003) DAVID: database for annotation, visualization, and integrated discovery. Genome Biol 4(5):P3
    • (2003) Genome Biol , vol.4 , Issue.5 , pp. 3
    • Dennis, G.1    Sherman, B.T.2    Hosack, D.A.3    Yang, J.4    Gao, W.5    Lane, H.C.6
  • 28
    • 33751088498 scopus 로고    scopus 로고
    • original Report by Thomas Lumley R package version 2.35-8 Accessed 14 Dec 2011
    • Therneau T, original Report by Thomas Lumley (2009) Survival: survival analysis, including penalised likelihood; R package version 2.35-8. http://CRAN.R-project.org/package=survival. Accessed 14 Dec 2011
    • (2009) Survival: Survival Analysis, Including Penalised Likelihood
    • Therneau, T.1
  • 30
    • 0026072872 scopus 로고
    • Pathological prognostic factors in breast cancer. I. the value of histological grade in breast cancer: Experience from a large study with long-term follow-up
    • 1757079 1:STN:280:DyaK38%2FpvVSltw%3D%3D 10.1111/j.1365-2559.1991. tb00229.x
    • Elston CW, Ellis IO (1991) Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology 19(5):403-410
    • (1991) Histopathology , vol.19 , Issue.5 , pp. 403-410
    • Elston, C.W.1    Ellis, I.O.2
  • 31
    • 77952465463 scopus 로고    scopus 로고
    • Use of ER/PR/HER2 subtypes in conjunction with the 2007 St Gallen Consensus Statement for early breast cancer
    • 10.1186/1471-2407-10-228 20492696 10.1186/1471-2407-10-228
    • Bauer K, Parise C, Caggiano V (2010) Use of ER/PR/HER2 subtypes in conjunction with the 2007 St Gallen Consensus Statement for early breast cancer. BMC Cancer 10:228. doi: 10.1186/1471-2407-10-228
    • (2010) BMC Cancer , vol.10 , pp. 228
    • Bauer, K.1    Parise, C.2    Caggiano, V.3
  • 32
    • 33845209913 scopus 로고    scopus 로고
    • A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
    • 10.1016/j.ccr.2006.10.008 17157791 1:CAS:528:DC%2BD28XhtlCnsrbE 10.1016/j.ccr.2006.10.008
    • Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T et al (2006) A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 10(6):515-527. doi: 10.1016/j.ccr.2006.10.008
    • (2006) Cancer Cell , vol.10 , Issue.6 , pp. 515-527
    • Neve, R.M.1    Chin, K.2    Fridlyand, J.3    Yeh, J.4    Baehner, F.L.5    Fevr, T.6
  • 33
    • 68549112897 scopus 로고    scopus 로고
    • Mechanics, malignancy, and metastasis: The force journey of a tumor cell
    • 10.1007/s10555-008-9173-4 19153673 10.1007/s10555-008-9173-4
    • Kumar S, Weaver VM (2009) Mechanics, malignancy, and metastasis: the force journey of a tumor cell. Cancer Metastasis Rev 28(1-2):113-127. doi: 10.1007/s10555-008-9173-4
    • (2009) Cancer Metastasis Rev , vol.28 , Issue.1-2 , pp. 113-127
    • Kumar, S.1    Weaver, V.M.2
  • 34
    • 0034051228 scopus 로고    scopus 로고
    • Rho family proteins in cell adhesion and cell migration
    • 10882865 1:CAS:528:DC%2BD3cXksFCrs74%3D 10.1016/S0959-8049(00)00091-5 This paper indicates that Rho and rac are in balance and that rho is associated with fibroblast morphology
    • Evers EE, Zondag GC, Malliri A, Price LS, ten Klooster JP, van der Kammen RA et al (2000) Rho family proteins in cell adhesion and cell migration. Eur J Cancer 36(10):1269-1274 This paper indicates that Rho and rac are in balance and that rho is associated with fibroblast morphology
    • (2000) Eur J Cancer , vol.36 , Issue.10 , pp. 1269-1274
    • Evers, E.E.1    Zondag, G.C.2    Malliri, A.3    Price, L.S.4    Ten Klooster, J.P.5    Van Der Kammen, R.A.6
  • 35
    • 23844488162 scopus 로고    scopus 로고
    • Regulation of cancer cell motility through actin reorganization
    • 10.1111/j.1349-7006.2005.00062.x 16053508 1:CAS:528:DC%2BD28XhtVOgtb4%3D 10.1111/j.1349-7006.2005.00062.x
    • Yamazaki D, Kurisu S, Takenawa T (2005) Regulation of cancer cell motility through actin reorganization. Cancer Sci 96(7):379-386. doi: 10.1111/j.1349-7006.2005.00062.x
    • (2005) Cancer Sci , vol.96 , Issue.7 , pp. 379-386
    • Yamazaki, D.1    Kurisu, S.2    Takenawa, T.3
  • 36
    • 68549122708 scopus 로고    scopus 로고
    • Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion
    • 10.1007/s10555-008-9170-7 19160018 1:CAS:528:DC%2BD1MXjsVWntr8%3D 10.1007/s10555-008-9170-7
    • Narumiya S, Tanji M, Ishizaki T (2009) Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion. Cancer Metastasis Rev 28(1-2):65-76. doi: 10.1007/s10555-008-9170-7
    • (2009) Cancer Metastasis Rev , vol.28 , Issue.1-2 , pp. 65-76
    • Narumiya, S.1    Tanji, M.2    Ishizaki, T.3
  • 37
    • 34547663507 scopus 로고    scopus 로고
    • Cell motility and cytoskeletal regulation in invasion and metastasis
    • 10.1007/s10911-007-9046-4 17557195 10.1007/s10911-007-9046-4
    • Kedrin D, van Rheenen J, Hernandez L, Condeelis J, Segall JE (2007) Cell motility and cytoskeletal regulation in invasion and metastasis. J Mammary Gland Biol Neoplasia 12(2-3):143-152. doi: 10.1007/s10911-007-9046-4
    • (2007) J Mammary Gland Biol Neoplasia , vol.12 , Issue.2-3 , pp. 143-152
    • Kedrin, D.1    Van Rheenen, J.2    Hernandez, L.3    Condeelis, J.4    Segall, J.E.5
  • 38
    • 33749538874 scopus 로고    scopus 로고
    • The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models
    • 10.1158/1535-7163.MCT-05-0440 16985048 1:CAS:528:DC%2BD28Xps1yns74%3D 10.1158/1535-7163.MCT-05-0440
    • Ying H, Biroc SL, Li WW, Alicke B, Xuan JA, Pagila R et al (2006) The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models. Mol Cancer Ther 5(9):2158-2164. doi: 10.1158/1535-7163.MCT-05-0440
    • (2006) Mol Cancer Ther , vol.5 , Issue.9 , pp. 2158-2164
    • Ying, H.1    Biroc, S.L.2    Li, W.W.3    Alicke, B.4    Xuan, J.A.5    Pagila, R.6
  • 39
    • 84857054821 scopus 로고    scopus 로고
    • Systematic assessment and meta-analysis of the efficacy and safety of fasudil in the treatment of cerebral vasospasm in patients with subarachnoid hemorrhage
    • 10.1007/s00228-011-1100-x 21837395 1:CAS:528:DC%2BC38XotVegsQ%3D%3D 10.1007/s00228-011-1100-x
    • Liu GJ, Wang ZJ, Wang YF, Xu LL, Wang XL, Liu Y et al (2012) Systematic assessment and meta-analysis of the efficacy and safety of fasudil in the treatment of cerebral vasospasm in patients with subarachnoid hemorrhage. Eur J Clin Pharmacol 68(2):131-139. doi: 10.1007/s00228-011-1100-x
    • (2012) Eur J Clin Pharmacol , vol.68 , Issue.2 , pp. 131-139
    • Liu, G.J.1    Wang, Z.J.2    Wang, Y.F.3    Xu, L.L.4    Wang, X.L.5    Liu, Y.6
  • 40
    • 78149353346 scopus 로고    scopus 로고
    • Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity
    • 10.1002/cm.20472 1:CAS:528:DC%2BC3cXhtFOrs7vM 10.1002/cm.20472
    • Amano M, Nakayama M, Kaibuchi K (2010) Rho-kinase/ROCK: a key regulator of the cytoskeleton and cell polarity. Cytoskeleton (Hoboken) 67(9):545-554. doi: 10.1002/cm.20472
    • (2010) Cytoskeleton (Hoboken) , vol.67 , Issue.9 , pp. 545-554
    • Amano, M.1    Nakayama, M.2    Kaibuchi, K.3
  • 41
    • 0038157026 scopus 로고    scopus 로고
    • Staging system for breast cancer: Revisions for the 6th edition of the AJCC cancer staging manual
    • 12875597 10.1016/S0039-6109(03)00034-3
    • Singletary SE, Allred C, Ashley P, Bassett LW, Berry D, Bland KI et al (2003) Staging system for breast cancer: revisions for the 6th edition of the AJCC cancer staging manual. Surg Clin North Am 83(4):803-819
    • (2003) Surg Clin North Am , vol.83 , Issue.4 , pp. 803-819
    • Singletary, S.E.1    Allred, C.2    Ashley, P.3    Bassett, L.W.4    Berry, D.5    Bland, K.I.6
  • 42
    • 0026075244 scopus 로고
    • Relationship among outcome, stage of disease, and histologic grade for 22,616 cases of breast cancer. the basis for a prognostic index
    • 1913453 1:STN:280:DyaK38%2FgsFWltw%3D%3D 10.1002/1097-0142(19911115)68: 10<2142: AID-CNCR2820681010>3.0.CO;2-D
    • Henson DE, Ries L, Freedman LS, Carriaga M (1991) Relationship among outcome, stage of disease, and histologic grade for 22,616 cases of breast cancer. The basis for a prognostic index. Cancer 68(10):2142-2149
    • (1991) Cancer , vol.68 , Issue.10 , pp. 2142-2149
    • Henson, D.E.1    Ries, L.2    Freedman, L.S.3    Carriaga, M.4
  • 43
    • 79955507726 scopus 로고    scopus 로고
    • AJCC cancer staging manual
    • 1:CAS:528:DC%2BC3cXhtlamu7zJ 10.1001/jama.2010.1525
    • Egner JR (2010) AJCC cancer staging manual. JAMA 304(15):1726
    • (2010) JAMA , vol.304 , Issue.15 , pp. 1726
    • Egner, J.R.1
  • 44
    • 0025192243 scopus 로고
    • Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice
    • 2297709 1:STN:280:DyaK3c7isVansA%3D%3D
    • Price JE, Polyzos A, Zhang RD, Daniels LM (1990) Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice. Cancer Res 50(3):717-721
    • (1990) Cancer Res , vol.50 , Issue.3 , pp. 717-721
    • Price, J.E.1    Polyzos, A.2    Zhang, R.D.3    Daniels, L.M.4
  • 45
    • 33845191779 scopus 로고    scopus 로고
    • Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
    • 10.1016/j.ccr.2006.10.009 17157792 1:CAS:528:DC%2BD28XhtlCnsrbF 10.1016/j.ccr.2006.10.009
    • Chin K, DeVries S, Fridlyand J, Spellman PT, Roydasgupta R, Kuo WL et al (2006) Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell 10(6):529-541. doi: 10.1016/j.ccr.2006.10.009
    • (2006) Cancer Cell , vol.10 , Issue.6 , pp. 529-541
    • Chin, K.1    Devries, S.2    Fridlyand, J.3    Spellman, P.T.4    Roydasgupta, R.5    Kuo, W.L.6
  • 46
    • 78649467513 scopus 로고    scopus 로고
    • Does tumour dormancy offer a therapeutic target?
    • 10.1038/nrc2933 21048784 1:CAS:528:DC%2BC3cXhtlOht7nO 10.1038/nrc2933
    • Goss PE, Chambers AF (2010) Does tumour dormancy offer a therapeutic target? Nat Rev Cancer 10(12):871-877. doi: 10.1038/nrc2933
    • (2010) Nat Rev Cancer , vol.10 , Issue.12 , pp. 871-877
    • Goss, P.E.1    Chambers, A.F.2
  • 47
    • 57649202568 scopus 로고    scopus 로고
    • The RhoGDI-alpha/JNK signaling pathway plays a significant role in mycophenolic acid-induced apoptosis in an insulin-secreting cell line
    • 10.1016/j.cellsig.2008.11.009 19041939 1:CAS:528:DC%2BD1cXhsFamtb%2FI 10.1016/j.cellsig.2008.11.009
    • Park YJ, Ahn HJ, Chang HK, Kim JY, Huh KH, Kim MS et al (2009) The RhoGDI-alpha/JNK signaling pathway plays a significant role in mycophenolic acid-induced apoptosis in an insulin-secreting cell line. Cell Signal 21(2):356-364. doi: 10.1016/j.cellsig.2008.11.009
    • (2009) Cell Signal , vol.21 , Issue.2 , pp. 356-364
    • Park, Y.J.1    Ahn, H.J.2    Chang, H.K.3    Kim, J.Y.4    Huh, K.H.5    Kim, M.S.6
  • 48
    • 79251547681 scopus 로고    scopus 로고
    • Manipulating protein acetylation in breast cancer: A promising approach in combination with hormonal therapies?
    • 10.1155/2011/856985 21188173 10.1155/2011/856985
    • Linares A, Dalenc F, Balaguer P, Boulle N, Cavailles V (2011) Manipulating protein acetylation in breast cancer: a promising approach in combination with hormonal therapies? J Biomed Biotechnol 2011:856985. doi: 10.1155/2011/856985
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 856985
    • Linares, A.1    Dalenc, F.2    Balaguer, P.3    Boulle, N.4    Cavailles, V.5
  • 49
    • 33748082671 scopus 로고    scopus 로고
    • Prognosis and gene expression profiling of 20q13-amplified breast cancers
    • 10.1158/1078-0432.CCR-05-2339 16899599 1:CAS:528:DC%2BD28XnvVGksr0%3D 10.1158/1078-0432.CCR-05-2339
    • Ginestier C, Cervera N, Finetti P, Esteyries S, Esterni B, Adélaïde J et al (2006) Prognosis and gene expression profiling of 20q13-amplified breast cancers. Clin Cancer Res 12(15):4533-4544. doi: 10.1158/1078-0432.CCR-05-2339
    • (2006) Clin Cancer Res , vol.12 , Issue.15 , pp. 4533-4544
    • Ginestier, C.1    Cervera, N.2    Finetti, P.3    Esteyries, S.4    Esterni, B.5    Adélaïde, J.6
  • 50
    • 34250652449 scopus 로고    scopus 로고
    • Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series
    • 17545524 1:CAS:528:DC%2BD2sXmtVajur0%3D 10.1158/1078-0432.CCR-06-2765
    • Desmedt C, Piette F, Loi S, Wang Y, Lallemand F, Haibe-Kains B et al (2007) Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series. Clin Cancer Res 13(11):3207-3214
    • (2007) Clin Cancer Res , vol.13 , Issue.11 , pp. 3207-3214
    • Desmedt, C.1    Piette, F.2    Loi, S.3    Wang, Y.4    Lallemand, F.5    Haibe-Kains, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.