A naturally occuring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 44, 2013, Pages 17826-17831

  Thomas Chollier, Morgane ^a,e   Watson, Lisa C ^b   Cooper, Samantha B ^b   Pufall, Miles A ^c   Liu, Jennifer S ^d   Borzym, Katja ^a   Vingron, Martin ^a   Yamamoto, Keith R ^b   Meijsing, Sebastiaan H ^a  

^a MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; GLUCOCORTICOID RECEPTOR; ISOPROTEIN; STEROID RECEPTOR;

ALLOSTERISM; ARTICLE; CONFORMATIONAL TRANSITION; DNA BINDING; DNA SEQUENCE; DOWNSTREAM PROCESSING; GENE CONTROL; GENE EXPRESSION REGULATION; GENE LOCUS; GENETIC ASSOCIATION; HUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ALTERNATIVE RNA SPLICING; CHEMICAL STRUCTURE; CHROMATIN IMMUNOPRECIPITATION; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSCRIPTION; GENETICS; IMMUNOBLOTTING; MICROARRAY ANALYSIS; PHYSIOLOGY; PROTEIN CONFORMATION; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL LINE; SEQUENCE MOTIFS;

ALTERNATIVE SPLICING; AMINO ACIDS; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; HUMANS; IMMUNOBLOTTING; MICROARRAY ANALYSIS; MODELS, MOLECULAR; MUTAGENESIS, INSERTIONAL; PROTEIN CONFORMATION; PROTEIN ISOFORMS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, GLUCOCORTICOID; TRANSCRIPTION, GENETIC;

ALTERNATIVE SPLICING; SEQUENCE MOTIFS; STEROID HORMONE RECEPTOR;

EID: 84887053531     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1316235110     Document Type: Article

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