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Volumn 58, Issue , 2014, Pages 126-135

Update on long-term treatment with bisphosphonates for postmenopausal osteoporosis: A systematic review

Author keywords

Bisphosphonate; Bone mineral density; Fracture; Long term; Postmenopausal osteoporosis

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; IBANDRONIC ACID; PLACEBO; RISEDRONIC ACID; ZOLEDRONIC ACID;

EID: 84887011575     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2013.09.023     Document Type: Review
Times cited : (168)

References (63)
  • 1
    • 77954254610 scopus 로고    scopus 로고
    • National Osteoporosis Foundation, National Osteoporosis Foundation, [Available at: Accessed: September 18, 2013]
    • National Osteoporosis Foundation Clinician's guide to prevention and treatment of osteoporosis 2010, National Osteoporosis Foundation, [Available at: http://www.nof.org/files/nof/public/content/file/344/upload/159.pdf. Accessed: September 18, 2013].
    • (2010) Clinician's guide to prevention and treatment of osteoporosis
  • 2
    • 84856365773 scopus 로고    scopus 로고
    • National Institutes of Health Osteoporosis and Related Bone Diseases National Resource Centre, National Institutes of Health, [Available at: Accessed: September 18, 2013]
    • National Institutes of Health Osteoporosis and Related Bone Diseases National Resource Centre Osteoporosis overview 2012, National Institutes of Health, [Available at: http://www.niams.nih.gov/Health_Info/Bone/Osteoporosis/overview.asp. Accessed: September 18, 2013].
    • (2012) Osteoporosis overview
  • 3
    • 0037347604 scopus 로고    scopus 로고
    • Estimating hip fracture morbidity, mortality and costs
    • Braithwaite R.S., Col N.F., Wong J.B. Estimating hip fracture morbidity, mortality and costs. J Am Geriatr Soc 2003, 51:364-370.
    • (2003) J Am Geriatr Soc , vol.51 , pp. 364-370
    • Braithwaite, R.S.1    Col, N.F.2    Wong, J.B.3
  • 4
    • 84886993117 scopus 로고    scopus 로고
    • The National Hip Fracture Database, The National Hip Fracture Database, [Available at: Accessed: September 18, 2013.]
    • The National Hip Fracture Database National hip fracture database national report 2012 2012, The National Hip Fracture Database, [Available at: http://www.hqip.org.uk/assets/NCAPOP-Library/NCAPOP-2012-13/Hip-Fracture-Database-Audit-Report-pub-2012.pdf. Accessed: September 18, 2013.].
    • (2012) National hip fracture database national report 2012
  • 5
    • 84864871358 scopus 로고    scopus 로고
    • Regional and age-related variations in the proportions of hip fractures and major fractures among postmenopausal women: the Global Longitudinal Study of Osteoporosis in Women
    • Pfeilschifter J., Cooper C., Watts N.B., Flahive J., Saag K.G., Adachi J.D., et al. Regional and age-related variations in the proportions of hip fractures and major fractures among postmenopausal women: the Global Longitudinal Study of Osteoporosis in Women. Osteoporos Int 2012, 23:2179-2188.
    • (2012) Osteoporos Int , vol.23 , pp. 2179-2188
    • Pfeilschifter, J.1    Cooper, C.2    Watts, N.B.3    Flahive, J.4    Saag, K.G.5    Adachi, J.D.6
  • 6
    • 0037291756 scopus 로고    scopus 로고
    • Long-term efficacy of risedronate: a 5-year placebo-controlled clinical experience
    • Sorensen O.H., Crawford G.M., Mulder H., Hosking D.J., Gennari C., Mellstrom D., et al. Long-term efficacy of risedronate: a 5-year placebo-controlled clinical experience. Bone 2003, 32:120-126.
    • (2003) Bone , vol.32 , pp. 120-126
    • Sorensen, O.H.1    Crawford, G.M.2    Mulder, H.3    Hosking, D.J.4    Gennari, C.5    Mellstrom, D.6
  • 7
    • 0141989663 scopus 로고    scopus 로고
    • New approaches to pharmacological treatment of osteoporosis
    • Akesson K. New approaches to pharmacological treatment of osteoporosis. Bull World Health Organ 2003, 81:657-664.
    • (2003) Bull World Health Organ , vol.81 , pp. 657-664
    • Akesson, K.1
  • 8
    • 0034530951 scopus 로고    scopus 로고
    • Fracture risk reduction with alendronate in women with osteoporosis: the Fracture Intervention Trial. FIT Research Group
    • Black D.M., Thompson D.E., Bauer D.C., Ensrud K., Musliner T., Hochberg M.C., et al. Fracture risk reduction with alendronate in women with osteoporosis: the Fracture Intervention Trial. FIT Research Group. J Clin Endocrinol Metab 2000, 85:4118-4124.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4118-4124
    • Black, D.M.1    Thompson, D.E.2    Bauer, D.C.3    Ensrud, K.4    Musliner, T.5    Hochberg, M.C.6
  • 9
  • 10
    • 69049083492 scopus 로고    scopus 로고
    • Denosumab for prevention of fractures in postmenopausal women with osteoporosis
    • Cummings S.R., San M.J., McClung M.R., Siris E.S., Eastell R., Reid I.R., et al. Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med 2009, 361:756-765.
    • (2009) N Engl J Med , vol.361 , pp. 756-765
    • Cummings, S.R.1    San, M.J.2    McClung, M.R.3    Siris, E.S.4    Eastell, R.5    Reid, I.R.6
  • 11
    • 9144233479 scopus 로고    scopus 로고
    • The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis
    • Meunier P.J., Roux C., Seeman E., Ortolani S., Badurski J.E., Spector T.D., et al. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med 2004, 350:459-468.
    • (2004) N Engl J Med , vol.350 , pp. 459-468
    • Meunier, P.J.1    Roux, C.2    Seeman, E.3    Ortolani, S.4    Badurski, J.E.5    Spector, T.D.6
  • 12
    • 12944291524 scopus 로고    scopus 로고
    • Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Vertebral Efficacy with Risedronate Therapy (VERT) Study Group
    • Reginster J., Minne H.W., Sorensen O.H., Hooper M., Roux C., Brandi M.L., et al. Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Vertebral Efficacy with Risedronate Therapy (VERT) Study Group. Osteoporos Int 2000, 11:83-91.
    • (2000) Osteoporos Int , vol.11 , pp. 83-91
    • Reginster, J.1    Minne, H.W.2    Sorensen, O.H.3    Hooper, M.4    Roux, C.5    Brandi, M.L.6
  • 13
    • 84858247953 scopus 로고    scopus 로고
    • Long-term treatment of osteoporosis in postmenopausal women: a review from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF)
    • Cooper C., Reginster J.Y., Cortet B., Diaz-Curiel M., Lorenc R.S., Kanis J.A., et al. Long-term treatment of osteoporosis in postmenopausal women: a review from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF). Curr Med Res Opin 2012, 28:475-491.
    • (2012) Curr Med Res Opin , vol.28 , pp. 475-491
    • Cooper, C.1    Reginster, J.Y.2    Cortet, B.3    Diaz-Curiel, M.4    Lorenc, R.S.5    Kanis, J.A.6
  • 14
    • 84861668653 scopus 로고    scopus 로고
    • Continuing bisphosphonate treatment for osteoporosis-for whom and for how long?
    • Black D.M., Bauer D.C., Schwartz A.V., Cummings S.R., Rosen C.J. Continuing bisphosphonate treatment for osteoporosis-for whom and for how long?. N Engl J Med 2012, 366:2051-2053.
    • (2012) N Engl J Med , vol.366 , pp. 2051-2053
    • Black, D.M.1    Bauer, D.C.2    Schwartz, A.V.3    Cummings, S.R.4    Rosen, C.J.5
  • 15
    • 84861705331 scopus 로고    scopus 로고
    • Bisphosphonates for osteoporosis-where do we go from here?
    • Whitaker M., Guo J., Kehoe T., Benson G. Bisphosphonates for osteoporosis-where do we go from here?. N Engl J Med 2012, 366:2048-2051.
    • (2012) N Engl J Med , vol.366 , pp. 2048-2051
    • Whitaker, M.1    Guo, J.2    Kehoe, T.3    Benson, G.4
  • 16
    • 43049109229 scopus 로고    scopus 로고
    • Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy
    • Russell R.G., Watts N.B., Ebetino F.H., Rogers M.J. Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy. Osteoporos Int 2008, 19:733-759.
    • (2008) Osteoporos Int , vol.19 , pp. 733-759
    • Russell, R.G.1    Watts, N.B.2    Ebetino, F.H.3    Rogers, M.J.4
  • 17
    • 84886999896 scopus 로고    scopus 로고
    • Merck Sharp & Dohme Limited, Last updated: November 13, 2012. Available at:, [Accessed: September 18, 2013]
    • Merck Sharp & Dohme Limited Fosamax® 10mg tablets summary of product characteristics. electronic Medicines Compendium Last updated: November 13, 2012. Available at:, [Accessed: September 18, 2013]. http://www.medicines.org.uk/emc/medicine/1175/SPC/Fosamax/.
    • Fosamax® 10mg tablets summary of product characteristics. electronic Medicines Compendium
  • 18
    • 84886994149 scopus 로고    scopus 로고
    • Merck Sharp & Dohme Limited, Last updated: October 22, 2012. Available at:, [Accessed: September 18, 2013]
    • Merck Sharp & Dohme Limited Fosamax® once weekly 70mg tablets: summary of product characteristics. electronic Medicines Compendium Last updated: October 22, 2012. Available at:, [Accessed: September 18, 2013]. http://www.medicines.org.uk/EMC/medicine/4115/SPC/Fosamax+Once+Weekly+70mg+Tablets/.
    • Fosamax® once weekly 70mg tablets: summary of product characteristics. electronic Medicines Compendium
  • 19
    • 84886995667 scopus 로고    scopus 로고
    • Novartis Pharmaceuticals UK Ltd., Last updated: September 6, 2013. Available at:, [Accessed: September 18, 2013]
    • Novartis Pharmaceuticals UK Ltd. Aclasta® 5mg injection for infusion: summary of product characteristics. electronic Medicines Compendium Last updated: September 6, 2013. Available at:, [Accessed: September 18, 2013]. http://www.medicines.org.uk/EMC/medicine/18171/SPC/Aclasta+5+mg+solution+for+infusion/.
    • Aclasta® 5mg injection for infusion: summary of product characteristics. electronic Medicines Compendium
  • 20
    • 84887005670 scopus 로고    scopus 로고
    • Roche Products Limited, Last updated: January 3, 2013. Available at:, [Accessed: September 18, 2013]
    • Roche Products Limited Bonviva® 3mg solution for injection: summary of product characteristics. electronic Medicines Compendium Last updated: January 3, 2013. Available at:, [Accessed: September 18, 2013]. http://www.medicines.org.uk/EMC/medicine/17546/SPC/Bonviva+3mg+3ml+solution+for+injection+in+pre-filled+syringe/.
    • Bonviva® 3mg solution for injection: summary of product characteristics. electronic Medicines Compendium
  • 24
    • 0004851872 scopus 로고    scopus 로고
    • Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group
    • Black D.M., Cummings S.R., Karpf D.B., Cauley J.A., Thompson D.E., Nevitt M.C., et al. Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet 1996, 348:1535-1541.
    • (1996) Lancet , vol.348 , pp. 1535-1541
    • Black, D.M.1    Cummings, S.R.2    Karpf, D.B.3    Cauley, J.A.4    Thompson, D.E.5    Nevitt, M.C.6
  • 25
    • 4544262219 scopus 로고    scopus 로고
    • Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis
    • Chesnut C.H., Skag A., Christiansen C., Recker R., Stakkestad J.A., Hoiseth A., et al. Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis. J Bone Miner Res 2004, 19:1241-1249.
    • (2004) J Bone Miner Res , vol.19 , pp. 1241-1249
    • Chesnut, C.H.1    Skag, A.2    Christiansen, C.3    Recker, R.4    Stakkestad, J.A.5    Hoiseth, A.6
  • 26
    • 0032583492 scopus 로고    scopus 로고
    • Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the Fracture Intervention Trial
    • Cummings S.R., Black D.M., Thompson D.E., Applegate W.B., Barrett-Connor E., Musliner T.A., et al. Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the Fracture Intervention Trial. JAMA 1998, 280:2077-2082.
    • (1998) JAMA , vol.280 , pp. 2077-2082
    • Cummings, S.R.1    Black, D.M.2    Thompson, D.E.3    Applegate, W.B.4    Barrett-Connor, E.5    Musliner, T.A.6
  • 27
    • 0033552255 scopus 로고    scopus 로고
    • Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial Vertebral Efficacy With Risedronate Therapy (VERT) Study Group
    • Harris S.T., Watts N.B., Genant H.K., McKeever C.D., Hangartner T., Keller M., et al. Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. JAMA 1999, 282:1344-1352.
    • (1999) JAMA , vol.282 , pp. 1344-1352
    • Harris, S.T.1    Watts, N.B.2    Genant, H.K.3    McKeever, C.D.4    Hangartner, T.5    Keller, M.6
  • 28
    • 33845890326 scopus 로고    scopus 로고
    • Effects of continuing or stopping alendronate after 5years of treatment: the Fracture Intervention Trial Long-term Extension (FLEX): a randomized trial
    • Black D.M., Schwartz A.V., Ensrud K.E., Cauley J.A., Levis S., Quandt S.A., et al. Effects of continuing or stopping alendronate after 5years of treatment: the Fracture Intervention Trial Long-term Extension (FLEX): a randomized trial. JAMA 2006, 296:2927-2938.
    • (2006) JAMA , vol.296 , pp. 2927-2938
    • Black, D.M.1    Schwartz, A.V.2    Ensrud, K.E.3    Cauley, J.A.4    Levis, S.5    Quandt, S.A.6
  • 29
    • 84856184102 scopus 로고    scopus 로고
    • The effect of 3 versus 6years of zoledronic acid treatment of osteoporosis: a randomized extension to the HORIZON-Pivotal Fracture Trial (PFT)
    • Black D.M., Reid I.R., Boonen S., Bucci-Rechtweg C., Cauley J.A., Cosman F., et al. The effect of 3 versus 6years of zoledronic acid treatment of osteoporosis: a randomized extension to the HORIZON-Pivotal Fracture Trial (PFT). J Bone Miner Res 2012, 27:243-254.
    • (2012) J Bone Miner Res , vol.27 , pp. 243-254
    • Black, D.M.1    Reid, I.R.2    Boonen, S.3    Bucci-Rechtweg, C.4    Cauley, J.A.5    Cosman, F.6
  • 31
    • 84863617923 scopus 로고    scopus 로고
    • Long-term administration of quarterly IV ibandronate is effective and well tolerated in postmenopausal osteoporosis: 5-year data from the DIVA study long-term extension
    • Bianchi G., Czerwinski E., Kenwright A., Burdeska A., Recker R.R., Felsenberg D. Long-term administration of quarterly IV ibandronate is effective and well tolerated in postmenopausal osteoporosis: 5-year data from the DIVA study long-term extension. Osteoporos Int 2012, 23:1769-1778.
    • (2012) Osteoporos Int , vol.23 , pp. 1769-1778
    • Bianchi, G.1    Czerwinski, E.2    Kenwright, A.3    Burdeska, A.4    Recker, R.R.5    Felsenberg, D.6
  • 32
    • 40649109120 scopus 로고    scopus 로고
    • Efficacy and tolerability of intravenous ibandronate injections in postmenopausal osteoporosis: 2-year results from the DIVA study
    • Eisman J.A., Civitelli R., Adami S., Czerwinski E., Recknor C., Prince R., et al. Efficacy and tolerability of intravenous ibandronate injections in postmenopausal osteoporosis: 2-year results from the DIVA study. J Rheumatol 2008, 35:488-497.
    • (2008) J Rheumatol , vol.35 , pp. 488-497
    • Eisman, J.A.1    Civitelli, R.2    Adami, S.3    Czerwinski, E.4    Recknor, C.5    Prince, R.6
  • 33
    • 84863620654 scopus 로고    scopus 로고
    • Efficacy of monthly oral ibandronate is sustained over 5years: the MOBILE long-term extension study
    • Miller P.D., Recker R.R., Reginster J.Y., Riis B.J., Czerwinski E., Masanauskaite D., et al. Efficacy of monthly oral ibandronate is sustained over 5years: the MOBILE long-term extension study. Osteoporos Int 2012, 23:1747-1756.
    • (2012) Osteoporos Int , vol.23 , pp. 1747-1756
    • Miller, P.D.1    Recker, R.R.2    Reginster, J.Y.3    Riis, B.J.4    Czerwinski, E.5    Masanauskaite, D.6
  • 34
    • 33646228157 scopus 로고    scopus 로고
    • Efficacy and tolerability of once-monthly oral ibandronate in postmenopausal osteoporosis: 2year results from the MOBILE study
    • Reginster J.Y., Adami S., Lakatos P., Greenwald M., Stepan J.J., Silverman S.L., et al. Efficacy and tolerability of once-monthly oral ibandronate in postmenopausal osteoporosis: 2year results from the MOBILE study. Ann Rheum Dis 2006, 65:654-661.
    • (2006) Ann Rheum Dis , vol.65 , pp. 654-661
    • Reginster, J.Y.1    Adami, S.2    Lakatos, P.3    Greenwald, M.4    Stepan, J.J.5    Silverman, S.L.6
  • 35
  • 36
    • 0033678399 scopus 로고    scopus 로고
    • Skeletal benefits of alendronate: 7-year treatment of postmenopausal osteoporotic women. Phase III Osteoporosis Treatment Study Group
    • Tonino R.P., Meunier P.J., Emkey R., Rodriguez-Portales J.A., Menkes C.J., Wasnich R.D., et al. Skeletal benefits of alendronate: 7-year treatment of postmenopausal osteoporotic women. Phase III Osteoporosis Treatment Study Group. J Clin Endocrinol Metab 2000, 85:3109-3115.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3109-3115
    • Tonino, R.P.1    Meunier, P.J.2    Emkey, R.3    Rodriguez-Portales, J.A.4    Menkes, C.J.5    Wasnich, R.D.6
  • 37
    • 0028851590 scopus 로고
    • Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. The Alendronate Phase III Osteoporosis Treatment Study Group
    • Liberman U.A., Weiss S.R., Broll J., Minne H.W., Quan H., Bell N.H., et al. Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. The Alendronate Phase III Osteoporosis Treatment Study Group. N Engl J Med 1995, 333:1437-1443.
    • (1995) N Engl J Med , vol.333 , pp. 1437-1443
    • Liberman, U.A.1    Weiss, S.R.2    Broll, J.3    Minne, H.W.4    Quan, H.5    Bell, N.H.6
  • 38
    • 78649326406 scopus 로고    scopus 로고
    • Impact of treatments for postmenopausal osteoporosis (bisphosphonates, parathyroid hormone, strontium ranelate, and denosumab) on bone quality: a systematic review
    • Gallacher S.J., Dixon T. Impact of treatments for postmenopausal osteoporosis (bisphosphonates, parathyroid hormone, strontium ranelate, and denosumab) on bone quality: a systematic review. Calcif Tissue Int 2010, 87:469-484.
    • (2010) Calcif Tissue Int , vol.87 , pp. 469-484
    • Gallacher, S.J.1    Dixon, T.2
  • 39
    • 79960945083 scopus 로고    scopus 로고
    • The effect of antiresorptives on bone quality
    • Recker R.R., Armas L. The effect of antiresorptives on bone quality. Clin Orthop Relat Res 2011, 469:2207-2214.
    • (2011) Clin Orthop Relat Res , vol.469 , pp. 2207-2214
    • Recker, R.R.1    Armas, L.2
  • 40
    • 77952331323 scopus 로고    scopus 로고
    • Efficacy of continued alendronate for fractures in women with and without prevalent vertebral fracture: the FLEX trial
    • Schwartz A.V., Bauer D.C., Cummings S.R., Cauley J.A., Ensrud K.E., Palermo L., et al. Efficacy of continued alendronate for fractures in women with and without prevalent vertebral fracture: the FLEX trial. J Bone Miner Res 2010, 25:976-982.
    • (2010) J Bone Miner Res , vol.25 , pp. 976-982
    • Schwartz, A.V.1    Bauer, D.C.2    Cummings, S.R.3    Cauley, J.A.4    Ensrud, K.E.5    Palermo, L.6
  • 41
    • 84873692265 scopus 로고    scopus 로고
    • Who is at highest risk for new vertebral fractures after 3years of annual zoledronic acid and who should remain on treatment?
    • [Available at: Accessed: September 18, 2013]
    • Cosman F., Cauley J., Eastell R., Boonen S., Palermo L., Reid D.M., et al. Who is at highest risk for new vertebral fractures after 3years of annual zoledronic acid and who should remain on treatment?. J Bone Miner Res 2011, 26(S1). http://onlinelibrary.wiley.com/doi/10.1002/jbmr.v26.1s/issuetoc. [Available at: http://www.asbmr.org/Meetings/AnnualMeeting/AbstractDetail.aspx?aid=ce715699-8143-4b48-ae65-d2e10fbc79c7. Accessed: September 18, 2013].
    • (2011) J Bone Miner Res , vol.26 , Issue.S1
    • Cosman, F.1    Cauley, J.2    Eastell, R.3    Boonen, S.4    Palermo, L.5    Reid, D.M.6
  • 42
    • 2642571931 scopus 로고    scopus 로고
    • Statistical validation of surrogate endpoints: is bone density a valid surrogate for fracture?
    • Li Z., Chines A.A., Meredith M.P. Statistical validation of surrogate endpoints: is bone density a valid surrogate for fracture?. J Musculoskelet Neuronal Interact 2004, 4:64-74.
    • (2004) J Musculoskelet Neuronal Interact , vol.4 , pp. 64-74
    • Li, Z.1    Chines, A.A.2    Meredith, M.P.3
  • 44
    • 10144251796 scopus 로고    scopus 로고
    • Markers of bone resorption predict hip fracture in elderly women: the EPIDOS Prospective Study
    • Garnero P., Hausherr E., Chapuy M.C., Marcelli C., Grandjean H., Muller C., et al. Markers of bone resorption predict hip fracture in elderly women: the EPIDOS Prospective Study. J Bone Miner Res 1996, 11:1531-1538.
    • (1996) J Bone Miner Res , vol.11 , pp. 1531-1538
    • Garnero, P.1    Hausherr, E.2    Chapuy, M.C.3    Marcelli, C.4    Grandjean, H.5    Muller, C.6
  • 45
    • 34249653663 scopus 로고    scopus 로고
    • Alendronate treatment in women with normal to severely impaired renal function: an analysis of the fracture intervention trial
    • Jamal S.A., Bauer D.C., Ensrud K.E., Cauley J.A., Hochberg M., Ishani A., et al. Alendronate treatment in women with normal to severely impaired renal function: an analysis of the fracture intervention trial. J Bone Miner Res 2007, 22:503-508.
    • (2007) J Bone Miner Res , vol.22 , pp. 503-508
    • Jamal, S.A.1    Bauer, D.C.2    Ensrud, K.E.3    Cauley, J.A.4    Hochberg, M.5    Ishani, A.6
  • 49
    • 84857356298 scopus 로고    scopus 로고
    • Alendronate and atrial fibrillation: a meta-analysis of randomized placebo-controlled clinical trials
    • Barrett-Connor E., Swern A.S., Hustad C.M., Bone H.G., Liberman U.A., Papapoulos S., et al. Alendronate and atrial fibrillation: a meta-analysis of randomized placebo-controlled clinical trials. Osteoporos Int 2012, 23:233-245.
    • (2012) Osteoporos Int , vol.23 , pp. 233-245
    • Barrett-Connor, E.1    Swern, A.S.2    Hustad, C.M.3    Bone, H.G.4    Liberman, U.A.5    Papapoulos, S.6
  • 51
    • 77955981091 scopus 로고    scopus 로고
    • Atypical fractures of the femur and bisphosphonate therapy: a systematic review of case/case series studies
    • Giusti A., Hamdy N.A., Papapoulos S.E. Atypical fractures of the femur and bisphosphonate therapy: a systematic review of case/case series studies. Bone 2010, 47:169-180.
    • (2010) Bone , vol.47 , pp. 169-180
    • Giusti, A.1    Hamdy, N.A.2    Papapoulos, S.E.3
  • 52
    • 79955722153 scopus 로고    scopus 로고
    • Bisphosphonate use and atypical fractures of the femoral shaft
    • Schilcher J., Michaelsson K., Aspenberg P. Bisphosphonate use and atypical fractures of the femoral shaft. N Engl J Med 2011, 364:1728-1737.
    • (2011) N Engl J Med , vol.364 , pp. 1728-1737
    • Schilcher, J.1    Michaelsson, K.2    Aspenberg, P.3
  • 53
    • 84868651511 scopus 로고    scopus 로고
    • Atypical femoral fractures are a separate entity, characterized by highly specific radiographic features. A comparison of 59 cases and 218 controls
    • Schilcher J., Koeppen V., Ranstam J., Skripitz R., Michaelsson K., Aspenberg P. Atypical femoral fractures are a separate entity, characterized by highly specific radiographic features. A comparison of 59 cases and 218 controls. Bone 2013, 52:389-392.
    • (2013) Bone , vol.52 , pp. 389-392
    • Schilcher, J.1    Koeppen, V.2    Ranstam, J.3    Skripitz, R.4    Michaelsson, K.5    Aspenberg, P.6
  • 54
    • 84859907817 scopus 로고    scopus 로고
    • "Atypical femoral fractures" during bisphosphonate exposure in adult hypophosphatasia
    • Sutton R.A., Mumm S., Coburn S.P., Ericson K.L., Whyte M.P. "Atypical femoral fractures" during bisphosphonate exposure in adult hypophosphatasia. J Bone Miner Res 2012, 27:987-994.
    • (2012) J Bone Miner Res , vol.27 , pp. 987-994
    • Sutton, R.A.1    Mumm, S.2    Coburn, S.P.3    Ericson, K.L.4    Whyte, M.P.5
  • 55
    • 78751576040 scopus 로고    scopus 로고
    • Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report
    • Rizzoli R., Akesson K., Bouxsein M., Kanis J.A., Napoli N., Papapoulos S., et al. Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report. Osteoporos Int 2011, 22:373-390.
    • (2011) Osteoporos Int , vol.22 , pp. 373-390
    • Rizzoli, R.1    Akesson, K.2    Bouxsein, M.3    Kanis, J.A.4    Napoli, N.5    Papapoulos, S.6
  • 58
    • 34848841461 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research
    • Khosla S., Burr D., Cauley J., Dempster D.W., Ebeling P.R., Felsenberg D., et al. Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res 2007, 22:1479-1491.
    • (2007) J Bone Miner Res , vol.22 , pp. 1479-1491
    • Khosla, S.1    Burr, D.2    Cauley, J.3    Dempster, D.W.4    Ebeling, P.R.5    Felsenberg, D.6
  • 59
    • 84871623655 scopus 로고    scopus 로고
    • Bisphosphonate therapy for osteoporosis: benefits, risks, and drug holiday
    • McClung M., Harris S.T., Miller P.D., Bauer D.C., Davison K.S., Dian L., et al. Bisphosphonate therapy for osteoporosis: benefits, risks, and drug holiday. Am J Med 2013, 126:13-20.
    • (2013) Am J Med , vol.126 , pp. 13-20
    • McClung, M.1    Harris, S.T.2    Miller, P.D.3    Bauer, D.C.4    Davison, K.S.5    Dian, L.6
  • 60
    • 0034519794 scopus 로고    scopus 로고
    • Preanalytical variability of biochemical markers of bone turnover
    • Hannon R., Eastell R. Preanalytical variability of biochemical markers of bone turnover. Osteoporos Int 2000, 11(Suppl. 6):S30-S44.
    • (2000) Osteoporos Int , vol.11 , Issue.SUPPL. 6
    • Hannon, R.1    Eastell, R.2
  • 61
    • 4544255312 scopus 로고    scopus 로고
    • Impact of degenerative spinal diseases on bone mineral density of the lumbar spine in elderly women
    • Muraki S., Yamamoto S., Ishibashi H., Horiuchi T., Hosoi T., Orimo H., et al. Impact of degenerative spinal diseases on bone mineral density of the lumbar spine in elderly women. Osteoporos Int 2004, 15:724-728.
    • (2004) Osteoporos Int , vol.15 , pp. 724-728
    • Muraki, S.1    Yamamoto, S.2    Ishibashi, H.3    Horiuchi, T.4    Hosoi, T.5    Orimo, H.6
  • 62
    • 84859919843 scopus 로고    scopus 로고
    • Postmenopausal osteoporosis treatment with antiresorptives: effects of discontinuation or long-term continuation on bone turnover and fracture risk-a perspective
    • Boonen S., Ferrari S., Miller P.D., Eriksen E.F., Sambrook P.N., Compston J., et al. Postmenopausal osteoporosis treatment with antiresorptives: effects of discontinuation or long-term continuation on bone turnover and fracture risk-a perspective. J Bone Miner Res 2012, 27:963-974.
    • (2012) J Bone Miner Res , vol.27 , pp. 963-974
    • Boonen, S.1    Ferrari, S.2    Miller, P.D.3    Eriksen, E.F.4    Sambrook, P.N.5    Compston, J.6
  • 63
    • 79958762993 scopus 로고    scopus 로고
    • The kidney and bisphosphonates
    • Miller P.D. The kidney and bisphosphonates. Bone 2011, 49:77-81.
    • (2011) Bone , vol.49 , pp. 77-81
    • Miller, P.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.