메뉴 건너뛰기




Volumn 4, Issue , 2013, Pages

Metabolic profiling of the impact of oligofructose-enriched inulin in Crohn's disease patients: A double-blinded randomized controlled trial

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; BUTYRIC ACID; CARBOHYDRATE; HEPTANOATE; HEXANOIC ACID; INULIN; MALTODEXTRIN; MEDIUM CHAIN FATTY ACID; OLIGOFRUCTOSE ENRICHED INULIN; PARA CRESOL; PENTANOATE; PLACEBO; PREBIOTIC AGENT; UNCLASSIFIED DRUG;

EID: 84887005566     PISSN: None     EISSN: 2155384X     Source Type: Journal    
DOI: 10.1038/ctg.2012.24     Document Type: Article
Times cited : (78)

References (47)
  • 1
    • 0025887076 scopus 로고
    • Effect of fecal stream diversion on recurrence of crohns-disease in the neoterminal ileum
    • Rutgeerts P, Geboes K, Peeters M et al. Effect of fecal stream diversion on recurrence of crohns-disease in the neoterminal ileum. Lancet 1991; 338: 771-774.
    • (1991) Lancet , vol.338 , pp. 771-774
    • Rutgeerts, P.1    Geboes, K.2    Peeters, M.3
  • 3
    • 55949124035 scopus 로고    scopus 로고
    • Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
    • Sokol H, Pigneur B, Watterlot L et al. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci USA 2008; 105: 16731-16736.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16731-16736
    • Sokol, H.1    Pigneur, B.2    Watterlot, L.3
  • 4
    • 33645019411 scopus 로고    scopus 로고
    • Specificities of the fecal microbiota in inflammatory bowel disease
    • Sokol H, Seksik P, Rigottier-Gois L et al. Specificities of the fecal microbiota in inflammatory bowel disease. Inflamm Bowel Dis 2006; 12: 106-111.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 106-111
    • Sokol, H.1    Seksik, P.2    Rigottier-Gois, L.3
  • 5
    • 0345830652 scopus 로고    scopus 로고
    • Dysbiosis in inflammatory bowel disease
    • DOI 10.1136/gut.53.1.1
    • Tamboli CP, Neut C, Desreumaux P et al. Dysbiosis in inflammatory bowel disease. Gut 2004; 53: 1-4. (Pubitemid 38082999)
    • (2004) Gut , vol.53 , Issue.1 , pp. 1-4
    • Tamboli, C.P.1    Neut, C.2    Desreumaux, P.3    Colombel, J.F.4
  • 7
    • 0037302961 scopus 로고    scopus 로고
    • Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon
    • DOI 10.1136/gut.52.2.237
    • Seksik P, Rigottier-Gois L, Gramet G et al. Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon. Gut 2003; 52: 237-242. (Pubitemid 36115065)
    • (2003) Gut , vol.52 , Issue.2 , pp. 237-242
    • Seksik, P.1    Rigottier-Gois, L.2    Gramet, G.3    Sutren, M.4    Pochart, P.5    Marteau, P.6    Jian, R.7    Dore, J.8
  • 10
    • 66249129571 scopus 로고    scopus 로고
    • Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohn's disease
    • Willing B, Halfvarson J, Dicksved J et al. Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohn's disease. Inflamm Bowel Dis 2009; 15: 653-660.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 653-660
    • Willing, B.1    Halfvarson, J.2    Dicksved, J.3
  • 11
    • 79953748870 scopus 로고    scopus 로고
    • Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives
    • Joossens M, Huys G, Cnockaert M et al. Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives. Gut 2011; 60: 631-637.
    • (2011) Gut , vol.60 , pp. 631-637
    • Joossens, M.1    Huys, G.2    Cnockaert, M.3
  • 12
    • 0036176278 scopus 로고    scopus 로고
    • Prebiotics and lipid metabolism
    • DOI 10.1097/00041433-200202000-00009
    • Delzenne NM, Williams CM. Prebiotics and lipid metabolism. Curr Opin Lipidol 2002; 13: 61-67. (Pubitemid 34174630)
    • (2002) Current Opinion in Lipidology , vol.13 , Issue.1 , pp. 61-67
    • Delzenne, N.M.1    Williams, C.M.2
  • 13
    • 23044491563 scopus 로고    scopus 로고
    • Introducing inulin-type fructans
    • DOI 10.1079/BJN20041350
    • Roberfroid MB. Introducing inulin-type fructans. Br J Nutr 2006; 93: S13-S25. (Pubitemid 43073402)
    • (2005) British Journal of Nutrition , vol.93 , Issue.SUPPL.
    • Roberfroid, M.B.1
  • 14
    • 12744273405 scopus 로고    scopus 로고
    • Dietary modulation of the human colonic microbiota: Updating the concept of prebiotics
    • Gibson GR, Probert HM, Van Loo J et al. Dietary modulation of the human colonic microbiota: updating the concept of prebiotics. Nutr Res Rev 2004; 17: 259-275.
    • (2004) Nutr Res Rev , vol.17 , pp. 259-275
    • Gibson, G.R.1    Probert, H.M.2    Van Loo, J.3
  • 15
    • 39749160044 scopus 로고    scopus 로고
    • Baseline microbiota activity and initial bifidobacteria counts influence responses to prebiotic dosing in healthy subjects
    • DOI 10.1111/j.1365-2036.2007.03588.x
    • De Preter V, Vanhoutte T, Huys G et al. Baseline microbiota activity and influence responses to prebiotic initial bifidobacteria counts dosing in healthy subjects. Aliment Pharmacol Ther 2008; 27: 504-513. (Pubitemid 351300850)
    • (2008) Alimentary Pharmacology and Therapeutics , vol.27 , Issue.6 , pp. 504-513
    • De Preter, V.1    Vanhoutte, T.2    Huys, G.3    Swings, J.4    Rutgeerts, P.5    Verbeke, K.6
  • 17
    • 2442453484 scopus 로고    scopus 로고
    • Therapeutic manipulation of the enteric microflora in inflammatory bowel diseases: Antibiotics, probiotics, and prebiotics
    • DOI 10.1053/j.gastro.2004.03.024
    • Sartor RB. Therapeutic manipulation of the enteric microflora in inflammatory bowel diseases: antibiotics, probiotics, and prebiotics. Gastroenterology 2004; 126: 1620-1633. (Pubitemid 38649878)
    • (2004) Gastroenterology , vol.126 , Issue.6 , pp. 1620-1633
    • Sartor, R.B.1
  • 18
    • 84860569723 scopus 로고    scopus 로고
    • Effect of oligofructose-enriched inulin (OF-IN) on bacterial composition and disease activity of patients with Crohn's disease: Results from a double-blinded randomised controlled trial
    • Joossens M, De Preter V, Ballet V et al. Effect of oligofructose-enriched inulin (OF-IN) on bacterial composition and disease activity of patients with Crohn's disease: results from a double-blinded randomised controlled trial. Gut 2012; 61: 958.
    • (2012) Gut , vol.61 , pp. 958
    • Joossens, M.1    De Preter, V.2    Ballet, V.3
  • 19
    • 79958221480 scopus 로고    scopus 로고
    • Randomised, double-blind, placebocontrolled trial of fructo- oligosaccharides in active Crohn's disease
    • Benjamin JL, Hedin CR, Koutsoumpas A et al. Randomised, double-blind, placebocontrolled trial of fructo-oligosaccharides in active Crohn's disease. Gut 2011; 60: 923-929.
    • (2011) Gut , vol.60 , pp. 923-929
    • Benjamin, J.L.1    Hedin, C.R.2    Koutsoumpas, A.3
  • 20
    • 54349126970 scopus 로고    scopus 로고
    • High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota
    • Zoetendal EG, Rajilic-Stojanovic M, de Vos WM. High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota. Gut 2008; 57: 1605-1615.
    • (2008) Gut , vol.57 , pp. 1605-1615
    • Zoetendal, E.G.1    Rajilic-Stojanovic, M.2    De Vos, W.M.3
  • 21
    • 0032694577 scopus 로고    scopus 로고
    • 'Metabonomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
    • Nicholson JK, Lindon JC, Holmes E. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 1999; 29: 1181-1189.
    • (1999) Xenobiotica , vol.29 , pp. 1181-1189
    • Nicholson, J.K.1    Lindon, J.C.2    Holmes, E.3
  • 23
    • 68149099597 scopus 로고    scopus 로고
    • Metabolomics reveals metabolic biomarkers of Crohn's disease
    • Jansson J, Willing B, Lucio M et al. Metabolomics reveals metabolic biomarkers of Crohn's disease. PLoS One 2009; 4: e6386.
    • (2009) PLoS One , vol.4
    • Jansson, J.1    Willing, B.2    Lucio, M.3
  • 24
    • 66949180452 scopus 로고    scopus 로고
    • Characterization of inflammatory bowel disease with urinary metabolic profiling
    • Williams HR, Cox IJ, Walker DG et al. Characterization of inflammatory bowel disease with urinary metabolic profiling. Am J Gastroenterol 2009; 104: 1435-1444.
    • (2009) Am J Gastroenterol , vol.104 , pp. 1435-1444
    • Williams, H.R.1    Cox, I.J.2    Walker, D.G.3
  • 25
    • 77949652854 scopus 로고    scopus 로고
    • Correlation between the Crohn's disease activity and Harvey-Bradshaw indices in assessing Crohn's disease severity
    • Vermeire S, Schreiber S, Sandborn WJ et al. Correlation between the Crohn's disease activity and Harvey-Bradshaw indices in assessing Crohn's disease severity. Clin Gastroenterol Hepatol 2010; 8: 357-363.
    • (2010) Clin Gastroenterol Hepatol , vol.8 , pp. 357-363
    • Vermeire, S.1    Schreiber, S.2    Sandborn, W.J.3
  • 26
    • 72949119718 scopus 로고    scopus 로고
    • P-Cresyl sulfate serum concentrations in haemodialysis patients are reduced by the prebiotic oligofructose-enriched inulin
    • Meijers BK, De Preter V, Verbeke K et al. p-Cresyl sulfate serum concentrations in haemodialysis patients are reduced by the prebiotic oligofructose-enriched inulin. Nephrol Dial Transplant 2009; 25: 219-224.
    • (2009) Nephrol Dial Transplant , vol.25 , pp. 219-224
    • Meijers, B.K.1    De Preter, V.2    Verbeke, K.3
  • 27
    • 0032968933 scopus 로고    scopus 로고
    • Inulin oligofructose and intestinal function
    • Jenkins DJA, Kendall CWC, V Vuksan. Inulin oligofructose and intestinal function. J Nutr 1999; 129: 1431S-1433SS.
    • (1999) J Nutr , vol.129
    • Jenkins, D.J.A.1    Kendall, C.W.C.2    Vuksan, V.3
  • 28
    • 59049087320 scopus 로고    scopus 로고
    • Development of a screening method to determine the pattern of fermentation metabolites in faecal samples using on-line purgeand-trap gas chromatographic-mass spectrometric analysis
    • De Preter V, Van Staeyen G, Esser D et al. Development of a screening method to determine the pattern of fermentation metabolites in faecal samples using on-line purgeand-trap gas chromatographic-mass spectrometric analysis. J Chromatogr A 2009; 1216: 1476-1483.
    • (2009) J Chromatogr A , vol.1216 , pp. 1476-1483
    • De Preter, V.1    Van Staeyen, G.2    Esser, D.3
  • 29
    • 78650790464 scopus 로고    scopus 로고
    • High-throughput method for comparative analysis of denaturing gradient gel electrophoresis profiles from human fecal samples reveals significant increases in two bifidobacterial species after inulin-type prebiotic intake
    • Joossens M, Huys G, Van Steen K et al. High-throughput method for comparative analysis of denaturing gradient gel electrophoresis profiles from human fecal samples reveals significant increases in two bifidobacterial species after inulin-type prebiotic intake. FEMS Microbiol Ecol 2011; 75: 343-349.
    • (2011) FEMS Microbiol Ecol , vol.75 , pp. 343-349
    • Joossens, M.1    Huys, G.2    Van Steen, K.3
  • 30
    • 79955618774 scopus 로고    scopus 로고
    • Impact of the synbiotic combination of Lactobacillus casei shirota and oligofructose-enriched inulin on the fecal volatile metabolite profile in healthy subjects
    • De Preter V, Ghebretinsae AH, Abrahantes JC et al. Impact of the synbiotic combination of Lactobacillus casei shirota and oligofructose-enriched inulin on the fecal volatile metabolite profile in healthy subjects. Mol Nutr Food Res 2011; 55: 714-722.
    • (2011) Mol Nutr Food Res , vol.55 , pp. 714-722
    • De Preter, V.1    Ghebretinsae, A.H.2    Abrahantes, J.C.3
  • 31
    • 0001677717 scopus 로고
    • Controlling the false discovery rate - A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate - a practical and powerful approach to multiple testing. J Royal Stat Soc S B Methodolo 1995; 57: 289-300.
    • (1995) J Royal Stat Soc S B Methodolo , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 32
    • 60649096197 scopus 로고    scopus 로고
    • Marklund S, Christmansson M, Holmberg K et Al. (Eds). National Institute for Working Life: Stockholm, Sweden
    • Korpi A, Järnberg J, Pasanen A. Microbial volatile organic compounds (MVOC). In: Marklund S, Christmansson M, Holmberg K et al. (eds). National Institute for Working Life: Stockholm, Sweden, 2007 1-78.
    • (2007) Microbial Volatile Organic Compounds (MVOC) , pp. 1-78
    • Korpi, A.1    Järnberg, J.2    Pasanen, A.3
  • 33
    • 0019128183 scopus 로고
    • Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man
    • Roediger WEW. Role of anaerobic-bacteria in the metabolic welfare of the colonic mucosa in man. Gut 1980; 21: 793-798. (Pubitemid 11209227)
    • (1980) Gut , vol.21 , Issue.9 , pp. 793-798
    • Roediger, W.E.W.1
  • 35
    • 21344464730 scopus 로고    scopus 로고
    • HDAC inhibition prevents NF-B activation by suppressing proteasome activity: Down-regulation of proteasome subunit expression stabilizes IB
    • DOI 10.1016/j.bcp.2005.04.030, PII S0006295205002807
    • Place RF, Noonan EJ, Giardina C. HDAC inhibition prevents NF-kappa B activation by suppressing proteasome activity: down-regulation of proteasome subunit expression stabilizes I kappa B alpha. Biochem Pharmacol 2005; 70: 394-406. (Pubitemid 40905111)
    • (2005) Biochemical Pharmacology , vol.70 , Issue.3 , pp. 394-406
    • Place, R.F.1    Noonan, E.J.2    Giardina, C.3
  • 36
    • 78650883928 scopus 로고    scopus 로고
    • The impact of pre- and/or probiotics on human colonic metabolism: Does it affect human health?
    • De Preter V, Hamer HM, Windey K et al. The impact of pre- and/or probiotics on human colonic metabolism: does it affect human health? Mol Nutr Food Res 2011; 55: 46-57.
    • (2011) Mol Nutr Food Res , vol.55 , pp. 46-57
    • De Preter, V.1    Hamer, H.M.2    Windey, K.3
  • 37
    • 70149108957 scopus 로고    scopus 로고
    • In vitro kinetics of prebiotic inulin-type fructan fermentation by butyrate-producing colon bacteria: Implementation of online gas chromatography for quantitative analysis of carbon dioxide and hydrogen gas production
    • Falony G, Verschaeren A, De Bruycker F et al. In vitro kinetics of prebiotic inulin-type fructan fermentation by butyrate-producing colon bacteria: implementation of online gas chromatography for quantitative analysis of carbon dioxide and hydrogen gas production. Appl Environ Microbiol 2009; 75: 5884-5892.
    • (2009) Appl Environ Microbiol , vol.75 , pp. 5884-5892
    • Falony, G.1    Verschaeren, A.2    De Bruycker, F.3
  • 38
    • 84874880856 scopus 로고    scopus 로고
    • An analysis of volatiles in the headspace of the faeces of neonates
    • De Lacy Costello B, Ewen R, Ewer AK et al. An analysis of volatiles in the headspace of the faeces of neonates. J Breath Res 2008; 2: 037023.
    • (2008) J Breath Res , vol.2 , pp. 037023
    • De Lacy Costello, B.1    Ewen, R.2    Ewer, A.K.3
  • 41
    • 72049099843 scopus 로고    scopus 로고
    • The in vitro genotoxicity of ethanol and acetaldehyde
    • Kayani MA, Parry JM. The in vitro genotoxicity of ethanol and acetaldehyde. Toxicol In Vitro 2010; 24: 56-60.
    • (2010) Toxicol in Vitro , vol.24 , pp. 56-60
    • Kayani, M.A.1    Parry, J.M.2
  • 42
    • 0030975356 scopus 로고    scopus 로고
    • 8 fatty acids in Sprague-Dawley rat colonocytes
    • Jorgensen JR, Clausen MR, Mortensen PB. Oxidation of short and medium chain C2-C8 fatty acids in Sprague-Dawley rat colonocytes. Gut 1997; 40: 400-405. (Pubitemid 27145656)
    • (1997) Gut , vol.40 , Issue.3 , pp. 400-405
    • Jorgensen, J.R.1    Clausen, M.R.2    Mortensen, P.B.3
  • 43
    • 0027404555 scopus 로고
    • Sulphate reducing bacteria and hydrogen metabolism in the human large intestine
    • Gibson GR, Macfarlane GT, Cummings JH. Sulfate reducing bacteria and hydrogen metabolism in the human large-intestine. Gut 1993; 34: 437-439. (Pubitemid 23093480)
    • (1993) Gut , vol.34 , Issue.4 , pp. 437-439
    • Gibson, G.R.1    MacFarlane, G.T.2    Cummings, J.H.3
  • 47
    • 34848834177 scopus 로고    scopus 로고
    • Effect of oral lactulose on clinical and immunohistochemical parameters in patients with inflammatory bowel disease: A pilot study
    • Hafer A, Kramer S, Duncker S et al. Effect of oral lactulose on clinical and immunohistochemical parameters in patients with inflammatory bowel disease: a pilot study. BMC Gastroenterol 2007; 7: 36.
    • (2007) BMC Gastroenterol , vol.7 , pp. 36
    • Hafer, A.1    Kramer, S.2    Duncker, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.