-
1
-
-
80051761743
-
The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy
-
Kelly,P.N.et al. (2011) The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy. Cell Death Differ., 18, 1414-1424.
-
(2011)
Cell Death Differ
, vol.18
, pp. 1414-1424
-
-
Kelly, P.N.1
-
2
-
-
0028274733
-
Multiple subcellular localization of bcl-2: detection in nuclear outer membrane, endoplasmic reticulum membrane, and mitochondrial membranes
-
Akao,Y.et al. (1994) Multiple subcellular localization of bcl-2: detection in nuclear outer membrane, endoplasmic reticulum membrane, and mitochondrial membranes. Cancer Res., 54, 2468-2471.
-
(1994)
Cancer Res
, vol.54
, pp. 2468-2471
-
-
Akao, Y.1
-
3
-
-
0030868245
-
Bcl-2 overexpression enhances the metastatic potential of a human breast cancer line
-
Del Bufalo,D. et al. (1997) Bcl-2 overexpression enhances the metastatic potential of a human breast cancer line. FASEB J., 11, 947-953.
-
(1997)
FASEB J
, vol.11
, pp. 947-953
-
-
Del Bufalo, D.1
-
4
-
-
0034028402
-
bcl-2 over-expression enhances NF-kappaB activity and induces mmp-9 transcription in human MCF7(ADR) breast-cancer cells
-
Ricca,A.et al. (2000) bcl-2 over-expression enhances NF-kappaB activity and induces mmp-9 transcription in human MCF7(ADR) breast-cancer cells. Int. J. Cancer, 86, 188-196.
-
(2000)
Int. J. Cancer
, vol.86
, pp. 188-196
-
-
Ricca, A.1
-
5
-
-
27744449761
-
Bcl-2 overexpression in melanoma cells increases tumor progression-associated properties and in vivo tumor growth
-
Trisciuoglio,D.et al. (2005) Bcl-2 overexpression in melanoma cells increases tumor progression-associated properties and in vivo tumor growth. J. Cell. Physiol., 205, 414-421.
-
(2005)
J. Cell. Physiol.
, vol.205
, pp. 414-421
-
-
Trisciuoglio, D.1
-
6
-
-
0033041468
-
Potentiation of the malignant phenotype of the undifferentiated ARO thyroid cell line by insertion of the bcl-2 gene
-
Basolo,F.et al. (1999) Potentiation of the malignant phenotype of the undifferentiated ARO thyroid cell line by insertion of the bcl-2 gene. Int. J. Cancer, 81, 956-962.
-
(1999)
Int. J. Cancer
, vol.81
, pp. 956-962
-
-
Basolo, F.1
-
7
-
-
0141869788
-
Expression of antisense bcl-2 cDNA abolishes tumorigenicity and enhances chemosensitivity of human malignant glioma cells
-
Zhu,C.J.et al. (2003) Expression of antisense bcl-2 cDNA abolishes tumorigenicity and enhances chemosensitivity of human malignant glioma cells. J. Neurosci. Res., 74, 60-66.
-
(2003)
J. Neurosci. Res.
, vol.74
, pp. 60-66
-
-
Zhu, C.J.1
-
8
-
-
0034120314
-
Bcl-2 overexpression and hypoxia synergistically act to modulate vascular endothelial growth factor expression and in vivo angiogenesis in a breast carcinoma line
-
Biroccio,A.et al. (2000) Bcl-2 overexpression and hypoxia synergistically act to modulate vascular endothelial growth factor expression and in vivo angiogenesis in a breast carcinoma line. FASEB J., 14, 652-660.
-
(2000)
FASEB J
, vol.14
, pp. 652-660
-
-
Biroccio, A.1
-
9
-
-
0035819518
-
Angiogenic potential of prostate carcinoma cells overexpressing bcl-2
-
Fernandez,A.et al. (2001) Angiogenic potential of prostate carcinoma cells overexpressing bcl-2. J. Natl Cancer Inst., 93, 208-213.
-
(2001)
J. Natl Cancer Inst.
, vol.93
, pp. 208-213
-
-
Fernandez, A.1
-
10
-
-
0036719158
-
Bcl-2 overexpression in human melanoma cells increases angiogenesis through VEGF mRNA stabilization and HIF-1-mediated transcriptional activity
-
Iervolino,A.et al. (2002) Bcl-2 overexpression in human melanoma cells increases angiogenesis through VEGF mRNA stabilization and HIF-1-mediated transcriptional activity. FASEB J., 16, 1453-1455.
-
(2002)
FASEB J
, vol.16
, pp. 1453-1455
-
-
Iervolino, A.1
-
11
-
-
24344458927
-
Involvement of PI3K and MAPK signaling in bcl-2-induced vascular endothelial growth factor expression in melanoma cells
-
Trisciuoglio,D.et al. (2005) Involvement of PI3K and MAPK signaling in bcl-2-induced vascular endothelial growth factor expression in melanoma cells. Mol. Biol. Cell, 16, 4153-4162.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 4153-4162
-
-
Trisciuoglio, D.1
-
12
-
-
77955606618
-
Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90
-
Trisciuoglio,D.et al. (2010) Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90. PLoS One, 5, e11772.
-
(2010)
PLoS One
, vol.5
-
-
Trisciuoglio, D.1
-
13
-
-
79955805684
-
Involvement of BH4 domain of bcl-2 in the regulation of HIF-1-mediated VEGF expression in hypoxic tumor cells
-
Trisciuoglio,D.et al. (2011) Involvement of BH4 domain of bcl-2 in the regulation of HIF-1-mediated VEGF expression in hypoxic tumor cells. Cell Death Differ., 18, 1024-1035.
-
(2011)
Cell Death Differ
, vol.18
, pp. 1024-1035
-
-
Trisciuoglio, D.1
-
14
-
-
84874589230
-
Removal of the BH4 domain from Bcl-2 protein triggers an autophagic process that impairs tumor growth
-
Trisciuoglio,D.et al. (2013) Removal of the BH4 domain from Bcl-2 protein triggers an autophagic process that impairs tumor growth. Neoplasia, 15, 315-327.
-
(2013)
Neoplasia
, vol.15
, pp. 315-327
-
-
Trisciuoglio, D.1
-
15
-
-
34548092663
-
Modulation of bcl-xL in tumor cells regulates angiogenesis through CXCL8 expression
-
Giorgini,S.et al. (2007) Modulation of bcl-xL in tumor cells regulates angiogenesis through CXCL8 expression. Mol. Cancer Res., 5, 761-771.
-
(2007)
Mol. Cancer Res.
, vol.5
, pp. 761-771
-
-
Giorgini, S.1
-
16
-
-
0031985222
-
N-methylformamide induces changes on adhesive properties and lung-colonizing potential of M14 melanoma cells
-
Del Bufalo,D. et al. (1998) N-methylformamide induces changes on adhesive properties and lung-colonizing potential of M14 melanoma cells. Br. J. Cancer, 77, 210-215.
-
(1998)
Br. J. Cancer
, vol.77
, pp. 210-215
-
-
Del Bufalo, D.1
-
17
-
-
1842628551
-
Exogenous BH4/Bcl-2 peptide reverts coronary endothelial cell apoptosis induced by oxidative stress
-
Cantara,S.et al. (2004) Exogenous BH4/Bcl-2 peptide reverts coronary endothelial cell apoptosis induced by oxidative stress. J. Vasc. Res., 41, 202-207.
-
(2004)
J. Vasc. Res.
, vol.41
, pp. 202-207
-
-
Cantara, S.1
-
18
-
-
0035941360
-
Transient expression of wild-type or mitochondrially targeted Bcl-2 induces apoptosis, whereas transient expression of endoplasmic reticulum-targeted Bcl-2 is protective against Bax-induced cell death
-
Wang,N.S.et al. (2001) Transient expression of wild-type or mitochondrially targeted Bcl-2 induces apoptosis, whereas transient expression of endoplasmic reticulum-targeted Bcl-2 is protective against Bax-induced cell death. J. Biol. Chem., 276, 44117-44128.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 44117-44128
-
-
Wang, N.S.1
-
19
-
-
0032848297
-
Linkage of the BH4 domain of Bcl-2 and the nuclear factor kappaB signaling pathway for suppression of apoptosis
-
de Moissac,D. et al. (1999) Linkage of the BH4 domain of Bcl-2 and the nuclear factor kappaB signaling pathway for suppression of apoptosis. J. Biol. Chem., 274, 29505-29509.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 29505-29509
-
-
de Moissac, D.1
-
20
-
-
20444456293
-
Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kappaB and CXC chemokines
-
Karl,E.et al. (2005) Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kappaB and CXC chemokines. Cancer Res., 65, 5063-5069.
-
(2005)
Cancer Res
, vol.65
, pp. 5063-5069
-
-
Karl, E.1
-
21
-
-
35448971378
-
Bcl-2 orchestrates a cross-talk between endothelial and tumor cells that promotes tumor growth
-
Kaneko,T.et al. (2007) Bcl-2 orchestrates a cross-talk between endothelial and tumor cells that promotes tumor growth. Cancer Res., 67, 9685-9693.
-
(2007)
Cancer Res
, vol.67
, pp. 9685-9693
-
-
Kaneko, T.1
-
22
-
-
61949264009
-
Bcl-2 mediated modulation of vascularization in prostate cancer xenografts
-
Sakai,Y.et al. (2009) Bcl-2 mediated modulation of vascularization in prostate cancer xenografts. Prostate, 69, 459-470.
-
(2009)
Prostate
, vol.69
, pp. 459-470
-
-
Sakai, Y.1
-
23
-
-
37549028456
-
Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization
-
Liu,Y.V.et al. (2007) Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization. J. Biol. Chem., 282, 37064-37073.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 37064-37073
-
-
Liu, Y.V.1
-
24
-
-
0037329351
-
The role of various Bcl-2 domains in the anti-proliferative effect and modulation of cellular glutathione levels: a prominent role for the BH4 domain
-
Hoetelmans,R.W.et al. (2003) The role of various Bcl-2 domains in the anti-proliferative effect and modulation of cellular glutathione levels: a prominent role for the BH4 domain. Cell Prolif., 36, 35-44.
-
(2003)
Cell Prolif
, vol.36
, pp. 35-44
-
-
Hoetelmans, R.W.1
-
25
-
-
33744907788
-
Bcl2 suppresses DNA repair by enhancing c-Myc transcriptional activity
-
Jin,Z.et al. (2006) Bcl2 suppresses DNA repair by enhancing c-Myc transcriptional activity. J. Biol. Chem., 281, 14446-14456.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 14446-14456
-
-
Jin, Z.1
-
26
-
-
39549112507
-
Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway
-
Wang,Q.et al. (2008) Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway. Mol. Cell, 29, 488-498.
-
(2008)
Mol. Cell
, vol.29
, pp. 488-498
-
-
Wang, Q.1
-
27
-
-
34247356153
-
Molecular determinants of the subcellular localization of the Drosophila Bcl-2 homologues DEBCL and BUFFY
-
Doumanis,J.et al. (2007) Molecular determinants of the subcellular localization of the Drosophila Bcl-2 homologues DEBCL and BUFFY. Cell Death Differ., 14, 907-915.
-
(2007)
Cell Death Differ
, vol.14
, pp. 907-915
-
-
Doumanis, J.1
-
28
-
-
0037421190
-
Characterization of the signal that directs Bclx(L), but not Bcl-2, to the mitochondrial outer membrane
-
Kaufmann,T.et al. (2003) Characterization of the signal that directs Bclx(L), but not Bcl-2, to the mitochondrial outer membrane. J. Cell Biol., 160, 53-64.
-
(2003)
J. Cell Biol.
, vol.160
, pp. 53-64
-
-
Kaufmann, T.1
-
29
-
-
78649631989
-
Apoptosis: embedded in membranes
-
Bogner,C.et al. (2010) Apoptosis: embedded in membranes. Curr. Opin. Cell Biol., 22, 845-851.
-
(2010)
Curr. Opin. Cell Biol.
, vol.22
, pp. 845-851
-
-
Bogner, C.1
-
30
-
-
33845991209
-
Bcl-2 localized at the nuclear compartment induces apoptosis after transient overexpression
-
Portier,B.P.et al. (2006) Bcl-2 localized at the nuclear compartment induces apoptosis after transient overexpression. J. Biol. Chem., 281, 40493-40502.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 40493-40502
-
-
Portier, B.P.1
-
31
-
-
0034090212
-
Suppression of transcription factor NF-kappaB activity by Bcl-2 protein in NIH3T3 cells: implication of a novel NF-kappaB p50-Bcl-2 complex for the anti-apoptotic function of Bcl-2
-
Hour,T.C.et al. (2000) Suppression of transcription factor NF-kappaB activity by Bcl-2 protein in NIH3T3 cells: implication of a novel NF-kappaB p50-Bcl-2 complex for the anti-apoptotic function of Bcl-2. Eur. J. Cell Biol., 79, 121-129.
-
(2000)
Eur. J. Cell Biol.
, vol.79
, pp. 121-129
-
-
Hour, T.C.1
-
32
-
-
77953617188
-
Nuclear translocation and calpain-dependent reduction of Bcl-2 after neonatal cerebral hypoxia-ischemia
-
Zhu,C.et al. (2010) Nuclear translocation and calpain-dependent reduction of Bcl-2 after neonatal cerebral hypoxia-ischemia. Brain. Behav. Immun., 24, 822-830.
-
(2010)
Brain. Behav. Immun.
, vol.24
, pp. 822-830
-
-
Zhu, C.1
-
33
-
-
0028157171
-
Subcellular localization of the bcl-2 protein in malignant and normal lymphoid cells
-
de Jong,D. et al. (1994) Subcellular localization of the bcl-2 protein in malignant and normal lymphoid cells. Cancer Res., 54, 256-260.
-
(1994)
Cancer Res
, vol.54
, pp. 256-260
-
-
de Jong, D.1
-
34
-
-
74249098821
-
Regulation of stress-induced nuclear protein redistribution: a new function of Bax and Bak uncoupled from Bcl-x(L)
-
Lindenboim,L.et al. (2010) Regulation of stress-induced nuclear protein redistribution: a new function of Bax and Bak uncoupled from Bcl-x(L). Cell Death Differ., 17, 346-359.
-
(2010)
Cell Death Differ
, vol.17
, pp. 346-359
-
-
Lindenboim, L.1
-
35
-
-
84872435565
-
Regulation of nuclear envelope permeability in cell death and survival
-
Strasser,C.et al. (2012) Regulation of nuclear envelope permeability in cell death and survival. Nucleus, 3, 540-551.
-
(2012)
Nucleus
, vol.3
, pp. 540-551
-
-
Strasser, C.1
-
36
-
-
39149098464
-
Nuclear translocation of hypoxia-inducible factors (HIFs): involvement of the classical importin alpha/beta pathway
-
Depping,R.et al. (2008) Nuclear translocation of hypoxia-inducible factors (HIFs): involvement of the classical importin alpha/beta pathway. Biochim. Biophys. Acta, 1783, 394-404.
-
(2008)
Biochim. Biophys. Acta
, vol.1783
, pp. 394-404
-
-
Depping, R.1
-
37
-
-
70350126918
-
Transport of hypoxia-inducible factor HIF-1alpha into the nucleus involves importins 4 and 7
-
Chachami,G.et al. (2009) Transport of hypoxia-inducible factor HIF-1alpha into the nucleus involves importins 4 and 7. Biochem. Biophys. Res. Commun., 390, 235-240.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.390
, pp. 235-240
-
-
Chachami, G.1
-
38
-
-
15444344269
-
Bcl-2 inhibits p53 nuclear import following DNA damage
-
Beham,A.et al. (1997) Bcl-2 inhibits p53 nuclear import following DNA damage. Oncogene, 15, 2767-2772.
-
(1997)
Oncogene
, vol.15
, pp. 2767-2772
-
-
Beham, A.1
-
39
-
-
80055032640
-
Promotion of tumor cell metastasis and vasculogenic mimicry by way of transcription coactivation by Bcl-2 and Twist1: a study of hepatocellular carcinoma
-
Sun,T.et al. (2011) Promotion of tumor cell metastasis and vasculogenic mimicry by way of transcription coactivation by Bcl-2 and Twist1: a study of hepatocellular carcinoma. Hepatology, 54, 1690-1706.
-
(2011)
Hepatology
, vol.54
, pp. 1690-1706
-
-
Sun, T.1
-
40
-
-
0032037896
-
Nuclear overexpression of bcl-2 oncoprotein during the progression of human stomach cancer
-
Lee,S.S.et al. (1998) Nuclear overexpression of bcl-2 oncoprotein during the progression of human stomach cancer. J. Korean Med. Sci., 13, 153-158.
-
(1998)
J. Korean Med. Sci.
, vol.13
, pp. 153-158
-
-
Lee, S.S.1
-
41
-
-
84867990000
-
Coexpression of Bcl-2 with epithelial-mesenchymal transition regulators is a prognostic indicator in hepatocellular carcinoma
-
Zhao,N.et al. (2012) Coexpression of Bcl-2 with epithelial-mesenchymal transition regulators is a prognostic indicator in hepatocellular carcinoma. Med. Oncol., 29, 2780-2792.
-
(2012)
Med. Oncol.
, vol.29
, pp. 2780-2792
-
-
Zhao, N.1
|