Recombinant protein YbgF induces protective immunity against Rickettsia heilongjiangensis infection in C3H/HeN mice

Vaccine

Volumn 31, Issue 48, 2013, Pages 5643-5650

  Qi, Yong ^a   Xiong, Xiaolu ^a   Duan, Changsong ^a   Jiao, Jun ^a   Gong, Wenping ^a   Wen, Bohai ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

Far Eastern spotted fever; Protective antigen; Rickettsia heilongjiangensis; Serum neutralization; Surface protein; Th1 type immune response

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; RECOMBINANT PROTEIN; RECOMBINANT PROTEIN PRSA; RECOMBINANT PROTEIN YBGF; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENDOTHELIUM CELL; IMMUNIZATION; IMMUNOGENICITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RICKETTSIA; RICKETTSIA HEILONGJIANGENSIS; RICKETTSIA HEILONGJIANGENSIS INFECTION; RICKETTSIACEAE INFECTION;

FAR-EASTERN SPOTTED FEVER; OD(450); OPTICAL DENSITY AT 450NM; PROTECTIVE ANTIGEN; RECOMBINANT PRSA; RECOMBINANT YBGF; RICKETTSIA HEILONGJIANGENSIS; RPRSA; RYBGF; SERUM NEUTRALIZATION; SURFACE PROTEIN; TH1-TYPE IMMUNE RESPONSE; WCA; WHOLE CELL ANTIGENS;

ANIMAL STRUCTURES; ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODIES, NEUTRALIZING; ANTIGENS, BACTERIAL; BACTERIAL LOAD; BACTERIAL PROTEINS; BACTERIAL VACCINES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CYTOKINES; DISEASE MODELS, ANIMAL; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C3H; RECOMBINANT PROTEINS; RICKETTSIA; RICKETTSIA INFECTIONS; TH1 CELLS; VACCINES, SUBUNIT; VACCINES, SYNTHETIC;

EID: 84886949124     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2013.09.064     Document Type: Article

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