17(E)-Picolinylidene androstane derivatives as potential inhibitors of prostate cancer cell growth: Antiproliferative activity and molecular docking studies

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 23, 2013, Pages 7257-7266

  Ajduković, Jovana J ^a   Djurendić, Evgenija A ^a   Petri, Edward T ^a   Klisurić, Olivera R ^a   Ćelić, Andjelka S ^a   Sakač, Marija N ^a   Jakimov, Dimitar S ^b   Gaši, Katarina M Penov ^a  

^a UNIVERSITY OF NOVI SAD   (Serbia)

^b ONCOLOGY INSTITUTE OF VOJVODINA   (Serbia)

Author keywords

17 Picolyl and 17(E) picolinylidene derivatives; Androstane; Antiproliferative activity; Antitumor; Molecular docking; Synthesis; Virtual screening

Indexed keywords

17 PICOLINYLIDEN 5ALPHA ANDROST 3 ENE; 17 PICOLINYLIDEN 5BETA ANDROST 3 ENE; 17 PICOLINYLIDENE ANDROST 3 EN 5ALPHA OL; 17 PICOLINYLIDENE ANDROST 4 EN 3 HYDRAZONE; 17 PICOLINYLIDENE ANDROST 4 EN 3 ON; 17 PICOLINYLIDENE ANDROSTANE DERIVATIVE; 17ALPHA PICOLYLANDROST 3 EN 5ALPHA,17BETA DIOL; 17ALPHA PICOLYLANDROSTANE DERIVATIVE; 17BETA HYDROXY 17ALPHA PICOLYL 4,5 SECOANDROST 3 YN 5 ONE; 17BETA HYDROXY 17ALPHA PICOLYLANDROST 4 EN 3 HYDRAZONE; 17BETA HYDROXY 17ALPHA PICOLYLANDROST 4 EN 3 ON; ABIRATERONE; ANDROGEN RECEPTOR; ANDROSTANE DERIVATIVE; AROMATASE; DOXORUBICIN; ESTROGEN RECEPTOR ALPHA; FORMESTANE; STEROID 17ALPHA MONOOXYGENASE; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BINDING AFFINITY; CANCER INHIBITION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR DOCKING; PROSTATE CANCER; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

17Α-PICOLYL AND 17(E)-PICOLINYLIDENE DERIVATIVES; ANDROSTANE; ANTIPROLIFERATIVE ACTIVITY; ANTITUMOR; MOLECULAR DOCKING; MWVNCXYRJNBSNB-ROWBJTNXSA-N; SYNTHESIS; VIRTUAL SCREENING;

ANDROSTANES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CRYSTALLOGRAPHY, X-RAY; HUMANS; MALE; MOLECULAR DOCKING SIMULATION; PROSTATE; PROSTATIC NEOPLASMS; PROTEIN BINDING; STEROID 17-ALPHA-HYDROXYLASE;

EID: 84886948729     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.09.063     Document Type: Article

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