Steroidal carbonitriles as potential aromatase inhibitors

Steroids

Volumn 77, Issue 8-9, 2012, Pages 850-857

  Yadav, Mange Ram ^a   Sabale, Prafulla M ^a   Giridhar, Rajani ^a   Zimmer, Christina ^b   Hartmann, Rolf W ^b  

^a M S UNIVERSITY OF BARODA   (India)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

4 Phenylthia derivatives; Aromatase inhibitors; Azasteroids; Breast cancer; Carbonitrile; d Seco derivatives

Indexed keywords

16 BETA CYANO 3BETA HYDROXY 5 ANDROSTEN 17 ONE; 16 BETA CYANO 4EPSILON,5 OXIDO 5EPSILON ANDROSTANE 3,17 DIONE; 16BETA CYANO 1,4 ANDROSTADIENE 3,17 DIONE; 16BETA CYANO 1,4,6 ANDROSTATRIENE 3,17 DIONE; 16BETA CYANO 17BETA HYDROXY 4 PHENYLTHIA 4 ANDROSTEN 3 ONE; 16BETA CYANO 3 ETHOXY 3,5 ANDROSTADIEN 17 ONE; 16BETA CYANO 4 ANDROSTENE 3,17 DIONE; 16BETA CYANO 4,6 ANDROSTADIENE 3,17 DIONE; 17BETA HYDROXY 4 PHENYLTHIA 4 ANDROSTEN 3 ONE; 3 ETHOXY 16,17 SECO 3,5 ANDROSTADIENE 16,17 DINITRILE; 3 OXO 16,17 SECO 1,4 ANDROSTADIENE 16,17 DINITRILE; 3 OXO 16,17 SECO 1,4,6 ANDROSTATRIENE 16,17 DINITRILE; 3 OXO 16,17 SECO 4 ANDROSTENE 16,17 DINITRILE; 3 OXO 16,17 SECO 4,6 ANDROSTADIENE 16,17 DINITRILE; 3BETA HYDROXY 16,17 SECO 5 ANDROSTENE 16,17 DINITRILE; 4 (4 AMINOPHENYL) THIA 17BETA HYDROXY 4 ANDROSTEN 3 ONE; AROMATASE; AROMATASE INHIBITOR; STEROIDAL CARBONITRILE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; ENZYME INHIBITION; KINETICS;

AROMATASE; AROMATASE INHIBITORS; AZASTEROIDS; ENZYME ACTIVATION; MOLECULAR STRUCTURE;

EID: 84861636934     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2012.04.010     Document Type: Article

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