UV-B-induced DNA damage and repair in the mouse lens

Investigative Ophthalmology and Visual Science

Volumn 54, Issue 10, 2013, Pages 6789-6797

  Mesa, Rosana ^a   Bassnett, Steven ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cortical cataract; DNA damage; UV B

Indexed keywords

PYRIMIDINE DIMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CORNEA THICKNESS; DNA DAMAGE; DNA REPAIR; EYE INJURY; HISTOLOGY; IMAGE ANALYSIS; IMMUNOFLUORESCENCE TEST; IRRADIATION; LIGHT DAMAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ULTRAVIOLET B RADIATION;

CORTICAL CATARACT; DNA DAMAGE; UV-B;

ANIMALS; CATARACT; DISEASE MODELS, ANIMAL; DNA DAMAGE; DNA REPAIR; LENS, CRYSTALLINE; MICE; MICE, INBRED C57BL; MUTATION; ULTRAVIOLET RAYS;

EID: 84886936244     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.13-12644     Document Type: Article

References (54)

1. Kopp G, Lean JL. A new, lower value of total solar irradiance: evidence and climate significance. Geophys Res Lett. 2011; 38. doi: 10. 1029/2010GL045777.
2. Diffey BL. Sources and measurement of ultraviolet radiation. Methods. 2002; 28: 4-13.
3. Sliney DH. Intraocular and crystalline lens protection from ultraviolet damage. Eye Contact Lens. 2011; 37: 250-258.
4. Lucas R, McMichael T, Smith W, Armstrong B. Solar Ultraviolet Radiation: Global Burden of Disease From Solar Ultraviolet Radiation. Geneva: World Health Organization; 2006.
5. Beukers R, Eker AP, Lohman PH. 50 years thymine dimer. DNA Repair (Amst). 2008; 7: 530-543.
6. Brash DE, Rudolph JA, Simon JA, et al. A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc Natl Acad Sci U S A. 1991; 88: 10124-10128.
7. Besaratinia A, Yoon JI, Schroeder C, Bradforth SE, Cockburn M, Pfeifer GP. Wavelength dependence of ultraviolet radiationinduced DNA damage as determined by laser irradiation suggests that cyclobutane pyrimidine dimers are the principal DNA lesions produced by terrestrial sunlight. FASEB J. 2011; 25: 3079-3091.
8. You YH, Lee DH, Yoon JH, Nakajima S, Yasui A, Pfeifer GP. Cyclobutane pyrimidine dimers are responsible for the vast majority of mutations induced by UVB irradiation in mammalian cells. J Biol Chem. 2001; 276: 44688-44694.
9. Friedberg EC. How nucleotide excision repair protects against cancer. Nat Rev Cancer. 2001; 1: 22-33.
10. Nouspikel T. DNA repair in mammalian cells: nucleotide excision repair: variations on versatility. Cell Mol Life Sci. 2009; 66: 994-1009.
11. Sugasawa K, Ng JM, Masutani C, et al. Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair. Mol Cell. 1998; 2: 223-232.
12. DiGiovanna JJ, Kraemer KH. Shining a light on xeroderma pigmentosum. J Invest Dermatol. 2012; 132: 785-796.
13. Oriowo OM, Cullen AP, Chou BR, Sivak JG. Action spectrum and recovery for in vitro UV-induced cataract using whole lenses. Invest Ophthalmol Vis Sci. 2001; 42: 2596-2602.
14. Andley UP, Lewis RM, Reddan JR, Kochevar IE. Action spectrum for cytotoxicity in the UVA-and UVB-wavelength region in cultured lens epithelial cells. Invest Ophthalmol Vis Sci. 1994; 35: 367-373.
15. Cullen AP. Ozone depletion and solar ultraviolet radiation: ocular effects, a United Nations environment programme perspective. Eye Contact Lens. 2011; 37: 185-190.
16. Taylor HR, West SK, Rosenthal FS, et al. Effect of ultraviolet radiation on cataract formation. N Engl J Med. 1988; 319: 1429-1433.
17. McCarty CA, Taylor HR. A review of the epidemiologic evidence linking ultraviolet radiation and cataracts. Dev Ophthalmol. 2002; 35: 21-31.
18. Dolin PJ, Johnson GJ. Solar ultraviolet radiation and ocular disease: a review of the epidemiological and experimental evidence. Ophthalmic Epidemiol. 1994; 1: 155-164.
19. Sasaki H, Kawakami Y, Ono M, et al. Localization of cortical cataract in subjects of diverse races and latitude. Invest Ophthalmol Vis Sci. 2003; 44: 4210-4214.
20. Abraham AG, Cox C, West S. The differential effect of ultraviolet light exposure on cataract rate across regions of the lens. Invest Ophthalmol Vis Sci. 2010; 51: 3919-3923.
21. Schein OD, West S, Munoz B, et al. Cortical lenticular opacification: distribution and location in a longitudinal study. Invest Ophthalmol Vis Sci. 1994; 35: 363-366.
22. Rochtchina E, Mitchell P, Coroneo M, Wang JJ, Cumming RG. Lower nasal distribution of cortical cataract: the Blue Mountains Eye Study. Clin Experiment Ophthalmol. 2001; 29: 111-115.
23. Coroneo MT. Albedo concentration in the anterior eye: a phenomenon that locates some solar diseases. Ophthalmic Surg. 1990; 21: 60-66.
24. Coroneo MT, Muller-Stolzenburg NW, Ho A. Peripheral light focusing by the anterior eye and the ophthalmohelioses. Ophthalmic Surg. 1991; 22: 705-711.
25. Dillon J, Zheng L, Merriam JC, Gaillard ER. The optical properties of the anterior segment of the eye: implications for cortical cataract. Exp Eye Res. 1999; 68: 785-795.
26. Hightower K, McCready J. The role of calcium in UVB-induced damage in irradiated ocular lenses. Photochem Photobiol. 1997; 65: 155-160.
27. Hightower KR, McCready JP, Borchman D. Membrane damage in UV-irradiated lenses. Photochem Photobiol. 1994; 59: 485-490.
28. Hightower KR, Reddan JR, McCready JP, Dziedzic DC. Lens epithelium: a primary target of UVB irradiation. Exp Eye Res. 1994; 59: 557-564.
29. Reddy GB, Bhat KS. Synergistic effect of UVB radiation and age on HMPS enzymes in rat lens homogenate. J Photochem Photobiol B. 1998; 43: 56-60.
30. Reddy GB, Bhat KS. UVB irradiation alters the activities and kinetic properties of the enzymes of energy metabolism in rat lens during aging. J Photochem Photobiol B. 1998; 42: 40-46.
31. Mori T, Nakane M, Hattori T, Matsunaga T, Ihara M, Nikaido O. Simultaneous establishment of monoclonal antibodies specific for either cyclobutane pyrimidine dimer or (6-4) photoproduct from the same mouse immunized with ultraviolet-irradiated DNA. Photochem Photobiol. 1991; 54: 225-232.
32. Hall PA, Levison DA, Woods AL, et al. Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: an index of cell proliferation with evidence of deregulated expression in some neoplasms. J Pathol. 1990; 162: 285-294.
33. Zigman S. Ocular light damage. Photochem Photobiol. 1993; 57: 1060-1068.
34. Zigman S. Environmental near-UV radiation and cataracts. Optom Vis Sci. 1995; 72: 899-901.
35. Hyka-Nouspikel N, Lemonidis K, Lu WT, Nouspikel T. Circulating human B lymphocytes are deficient in nucleotide excision repair and accumulate mutations upon proliferation. Blood. 2011; 117: 6277-6286.
36. Harding CV, Hughes WL, Bond VP, Schork P. Autoradiographic localization of tritiated thymidine in wholemount preparations of lens epithelium. Arch Ophthalmol. 1960; 63: 58-65.
37. Zigman S. Lens UVA photobiology. J Ocul Pharmacol Ther. 2000; 16: 161-165.
38. Kleiman NJ, Wang RR, Spector A. Ultraviolet light induced DNA damage and repair in bovine lens epithelial cells. Curr Eye Res. 1990; 9: 1185-1193.
39. Sidjanin D, Zigman S, Reddan J. DNA damage and repair in rabbit lens epithelial cells following UVA radiation. Curr Eye Res. 1993; 12: 773-781.
40. Andley UP, Song Z, Mitchell DL. DNA repair and survival in human lens epithelial cells with extended lifespan. Curr Eye Res. 1999; 18: 224-230.
41. Estil S, Olsen WM, Huitfeldt HS, Haaskjold E. UVB-induced formation of (6-4) photoproducts in the rat corneal epithelium. Acta Ophthalmol Scand. 1997; 75: 120-123.
42. Mallet JD, Rochette PJ. Ultraviolet light-induced cyclobutane pyrimidine dimers in rabbit eyes. Photochem Photobiol. 2011; 87: 1363-1368.
43. Henriksson JT, Bergmanson JP, Walsh JE. Ultraviolet radiation transmittance of the mouse eye and its individual media components. Exp Eye Res. 2010; 90: 382-387.
44. Walsh JE, Bergmanson JP, Koehler LV, Doughty MJ, Fleming DP, Harmey JH. Fibre optic spectrophotometry for the in vitro evaluation of ultraviolet radiation (UVR) spectral transmittance of rabbit corneas. Physiol Meas. 2008; 29: 375-388.
45. Reeve VE, Boehm-Wilcox C, Bosnic M, Reilly WG. Differential photoimmunoprotection by sunscreen ingredients is unrelated to epidermal cis urocanic acid formation in hairless mice. J Invest Dermatol. 1994; 103: 801-806.
46. Rebel H, Mosnier LO, Berg RJ, et al. Early p53-positive foci as indicators of tumor risk in ultraviolet-exposed hairless mice: kinetics of induction, effects of DNA repair deficiency, and p53 heterozygosity. Cancer Res. 2001; 61: 977-983.
47. Mitchell DL, Haipek CA, Clarkson JM. (6-4) Photoproducts are removed from the DNA of UV-irradiated mammalian cells more efficiently than cyclobutane pyrimidine dimers. Mutat Res. 1985; 143: 109-112.
48. Buterin T, Hess MT, Gunz D, Geacintov NE, Mullenders LH, Naegeli H. Trapping of DNA nucleotide excision repair factors by nonrepairable carcinogen adducts. Cancer Res. 2002; 62: 4229-4235.
49. Yamamoto A, Nakamura Y, Kobayashi N, et al. Neurons and astrocytes exhibit lower activities of global genome nucleotide excision repair than do fibroblasts. DNA Repair (Amst). 2007; 6: 649-657.
50. Nishiwaki Y, Kobayashi N, Imoto K, et al. Trichothiodystrophy fibroblasts are deficient in the repair of ultraviolet-induced cyclobutane pyrimidine dimers and (6-4) photoproducts. J Invest Dermatol. 2004; 122: 526-532.
51. Yeh JI, Levine AS, Du S, et al. Damaged DNA induced UVdamaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair. Proc Natl Acad Sci U S A. 2012; 109: E2737-E2746.
52. Tan T, Chu G. p53 Binds and activates the xeroderma pigmentosum DDB2 gene in humans but not mice. Mol Cell Biol. 2002; 22: 3247-3254.
53. Alekseev S, Kool H, Rebel H, et al. Enhanced DDB2 expression protects mice from carcinogenic effects of chronic UV-B irradiation. Cancer Res. 2005; 65: 10298-10306.
54. Osnes-Ringen O, Azqueta AO, Moe MC, et al. DNA damage in lens epithelium of cataract patients in vivo and ex vivo [published online ahead of print September 20, 2012]. Acta Ophthalmol. doi: 10. 1111/j. 1755-3768. 2012. 02500. x.