Expression of ectonucleotide pyrophosphatase-1 in end-plate chondrocytes with transforming growth factor beta 1 siRNA interference by cyclic mechanical tension

Chinese Medical Journal

Volumn 126, Issue 20, 2013, Pages 3886-3890

  Xu, Hong Guang ^a   Li, Zi Rui ^a   Wang, Hong ^a   Liu, Ping ^a   Xiang, Sheng Nan ^b   Wang, Chuang Dong ^b   Zhang, Xiao Ling ^b  

^a WANNAN MEDICAL COLLEGE   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cyclic mechanical tension; Ectonucleotide pyrophosphatase phosphodiesterase 1; Extracellular signal regulated kinase 1 2; Transforming growth factor beta 1

Indexed keywords

1, 4 DIAMINO 1, 4 BIS (2 AMINOPHENYLTHIO) 2, 3 DICYANOBUTADIENE; CYTOKINE; ECTONUCLEOTIDE PYROPHOSPHATASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARTILAGE CELL; CONTROLLED STUDY; GENE SILENCING; MECHANICAL STRESS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TENSION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CHONDROCYTES; PHOSPHORIC DIESTER HYDROLASES; PYROPHOSPHATASES; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STRESS, MECHANICAL; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84886881087     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.20130543     Document Type: Article

References (28)

1. Xu HG, Chen XW, Wang H, Lu LM, Liu P, Xia LZ. Correlation between chondrocyte apoptosis of vertebral cartilage endplate and degeneration of intervertebral disc. Natl Med J China (Chin) 2008; 88: 194-197.
2. Urban JP, Smith S, Fairbank JC. Nutrition of the intervertebral disc. Spine 2004; 29: 2700-2709.
3. Howell DS, Martel-Pelletier J, Pelletier JP, Morales S, Muniz O. NTP pyrophosphohydrolase in human chondrocalcinotic and osteoarthritic cartilage: further studies on histologic and subcellular distribution. Arthritis Rheum 1984; 27: 193-199.
4. Ryan LM, Wortmann RL, Karas B, Lynch MP, McCarty DJ. Pyrophosphohydrolase activity and inorganic pyrophosphate content of cultured human skin fibroblasts. Elevated levels in some patients with calcium pyrophosphate dehydrate deposition disease. J Clin Invest 1986; 77: 1689-1693.
5. Cailotto F, Bianchi A, Sebillaud S, Venkatesan N, Moulin D, Jouzeau JY, et al. Inorganic pyrophosphate generation by transforming growth factor-beta-1 is mainly dependent on ANK induction by Ras/Raf-1/extracellular signal regulated kinase pathways in chondrocytes. Arthritis Res Ther 2007; 9: R122.
6. Ryan LM, Rosenthal AK. Metabolism of extracellular pyrophosphate. Curr Opin Rheumatol 2003; 15: 311-314.
7. Rosenthal AK, Gohr CM, Henry LA, Le M. Participation of transglutaminase in the activation of latent transforming growth factor beta1 in aging articular cartilage. Arthritis Rheum 2000; 43: 1729-1733.
8. Terkeltaub RA. Inorganic pyrophosphate generation and disposition in pathophysiology. Am J Physiol Cell Physiol 2001; 281: C1-C11.
9. Lotz M, Rosen F, McCabe G, Quach J, Blanco F, Dudler J, et al. Interleukin 1 beta suppresses transforming growth factor-induced inorganic pyrophosphate (ppi) production and expression of the ppi-generating enzyme PC-1 in human chondrocytes. Proc Natl Acad Sci U S A 1995; 92: 10364-10368.
10. Johnson K, Vaingankar S, Chen Y, Moffa A, Goldring MB, Sano K, et al. Differential mechanisms of inorganic pyrophosphate production by plasma cell membrane glycoprotein-1 (pc-1) and B10 in chondrocytes. Arthritis Rheum 1999; 42: 1986-1997.
11. Xu HG, Li ZR, Wang H, Liu P, Xiang SN, Wang CD, et al. Intermittent cyclic mechanical tension-induced down-regulation of ectonucleotide pyrophosphatase phosphodiesterase 1 gene expression is mainly dependent on TGF-β1 in end-plate chondrocytes. Orthop Surg 2013; 5: 40-45.
12. Chang L, Karin M. Mammalian MAP kinase signalling cascades. Nature 2001; 410: 37-40.
13. Chaturvedi LS, Marsh HM, Basson MD. Src and focal adhesion kinase mediate mechanical strain-induced proliferation and ERK1/2 phosphorylation in human H441 pulmonary epithelial cells. Am J Physiol Cell Physiol 2007; 292: C1701-C1713.
14. Ryan JA, Eisner EA, DuRaine G, You Z, Reddi AH. Mechanical compression of articular cartilage induces chondrocyte proliferation and inhibits proteoglycan synthesis by activation of the ERK pathway: implications for tissue engineering and regenerative medicine. J Tissue Eng Regen Med 2009; 3: 107-116.
15. Han Y, Pan JS, Chen DP, Mao X Y, Qi YX, Yan ZQ. Proliferation of human periodontal ligament cells promoted by cyclic strain via ERK signaling pathway. J Med Biomech 2009; 24: 211-215.
16. Melrose J, Burkhardt D, Taylor TK, Dillon CT, Read R, Cake M. Calcification in the ovine intervertebral disc: a model of hydroxyapatite deposition disease. Eur Spine J 2009; 18: 479-489.
17. Xu HG, Chen XH, Ding GZ, Wang H, Wang LT, Chen XW. Effect of pcDNA3.1-vascular endothelial growth factor 165 recombined vector on vascular buds in rabbit vertebral cartilage endplate. Chin Med J 2012; 125: 4055-4060.
18. Bian Q, Liang QQ, Wan C, Hou W, Li CG, Zhao YJ, et al. Prolonged upright posture induces calcifed hypertrophy in the cartilage endplate in rat lumbar spine. Spine (Phila Pa 1976) 2011; 36: 2011-2020.
19. Xu HG, Zhang XH, Wang H, Liu P, Wang LT, Zuo CJ, et al. Intermittent cyclic mechanical tension induced calcification and down-regulation of ANK gene expression of endplate chondrocytes. Spine 2012; 37: 1192-1197.
20. Fermor B, Gundle R, Evans M, Emerton M, Pocock A, Murray D. Primary human osteoblast proliferation and prostaglandin E2 release in response to mechanical strain in vitro. Bone 1998; 22: 637-643.
21. Burr DB, Milgrom C. In vivo measurement of human tibial strains during vigorous activity. Bone 1996; 18: 405-410.
22. Harris RC, Haralson MA, Badr KF. Continuous stretch-relaxation in culture alters rat mesangial cell morphology, growth characteristics and metabolic activity. Lab Invest 1992; 66: 548-554.
23. Hirakata M, Kaname S, Chung UG, Joki N, Hori Y, Noda M, et al. Tyrosine kinase dependent expression of TGF-beta induced by stretch in mesangial cells. Kidney Int 1997; 51: 1028-1036.
24. Yasuda T, Kondo S, Homma T, Harris RC. Regulation of extracellular matrix by mechanical stress in rat glomerular mesangial cells. J Clin Invest 1996; 98: 1991-2000.
25. Riser BL, Cortes P, Heilig C, Grondin J, Ladson-Wofford S, Patterson D, et al. Cyclin stretching force selectively up regulates transforming growth factor-beta isoforms in cultured rat mesangial cells. Am J Pathol 1996; 148: 1915-1923.
26. Sohn P, Crowley M, Slattery E, Serra R. Developmental and TGF-beta-mediated regulation of ANK mRNA expression in cartilage and bone. Osteoarthritis Cartilage 2002; 10: 482-490.
27. Fitzgerald JB, Jin M, Chai DH, Siparsky P, Fanning P, Grodzinsky AJ. Shear- and compression-induced chondrocyte transcription requires MAPK activation in cartilage explants. J Biol Chem 2008; 283: 6735-6743.
28. Badger AM, Roshak AK, Cook MN, Newman-Tarr TM, Swift BA, Carlson K, et al. Differential effects of SB 24 242235, a selective P38 mitogen-activated protein kinase inhibitor on IL-1 treated bovine and human cartilage/chondrocyte cultures. Osteoarthritis Cartilage 2000; 8: 434-443.