Aberrant ZNF423 impedes B cell differentiation and is linked to adverse outcome of ETV6-RUNX1 negative B precursor acute lymphoblastic leukemia

Journal of Experimental Medicine

Volumn 210, Issue 11, 2013, Pages 2289-2304

  Harder, Lena ^a   Eschenburg, Georg ^a   Zech, Antonia ^a   Kriebitzsch, Neele ^a,d   Otto, Benjamin ^a   Streichert, Thomas ^a   Behlich, Anna Sophie ^a   Dierck, Kevin ^a   Klingler, Bine ^a   Hansen, Arne ^a   Stanulla, Martin ^b   Zimmermann, Martin ^b   Kremmer, Elisabeth ^c   Stocking, Carol ^d   Horstmann, Martin A ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; HISTONE DEACETYLASE; TRANSCRIPTION FACTOR ETV6; TRANSCRIPTION FACTOR RUNX1;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; B LYMPHOCYTE; CELL DIFFERENTIATION; CELL MATURATION; DNA METHYLATION; EPIGENETICS; GENE; GENE EXPRESSION; GENETIC DISORDER; HEMATOPOIETIC CELL; NUCLEOSOME; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; ZNF423 GENE;

ANIMALS; B-LYMPHOCYTES; BONE MORPHOGENETIC PROTEIN 2; CELL DIFFERENTIATION; CELL LINEAGE; CORE BINDING FACTOR ALPHA 2 SUBUNIT; DISEASE-FREE SURVIVAL; DNA METHYLATION; DNA-BINDING PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, LEUKEMIC; HEMATOPOIETIC STEM CELLS; MI-2 NUCLEOSOME REMODELING AND DEACETYLASE COMPLEX; MICE; NEOPLASM PROTEINS; ONCOGENE PROTEINS, FUSION; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROGNOSIS; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 84886835251     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20130497     Document Type: Article

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