Platelet-activating factor receptor blockade ameliorates aggregatibacter actinomycetemcomitans-induced periodontal disease in Mice

Infection and Immunity

Volumn 81, Issue 11, 2013, Pages 4244-4251

  Madeira, Mila Fernandes Moreira ^a   Queiroz Junior, Celso Martins ^a   Costa, Graciela Mitre ^a   Werneck, Silvia Maria Cordeiro ^a   Cisalpino, Daniel ^a   Garlet, Gustavo Pompermaier ^b   Teixeira, Mauro Martins ^a   Silva, Tarcília Aparecida ^a   Souza, Daniele G ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; CXCL1 CHEMOKINE; MODIPAFANT; PHOSPHOLIPID; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

AGGREGATIBACTER ACTINOMYCETEMCOMITANS; ALVEOLAR BONE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOFILM; CELL DIFFERENTIATION; CHRONIC INFLAMMATION; CONTROLLED STUDY; DISEASE COURSE; GINGIVA; IN VITRO STUDY; INOCULATION; KNOCKOUT MOUSE; MOUSE; NEUTROPHIL; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PERIODONTAL DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SALIVA; WILD TYPE;

EID: 84886794039     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01046-13     Document Type: Article

References (47)

1. Fives-Taylor PM, Meyer DH, Mintz KP, Brissette C. 1999. Virulence factors of Actinobacillus actinomycetemcomitans. Periodontol. 2000 20: 136-167.
2. Nakamura H, Fukusaki Y, Yoshimura A, Shiraishi C, Kishimoto M, Kaneko T, Hara Y. 2008. Lack of toll-like receptor 4 decreases lipopolysaccharide- induced bone resorption in C3H/HeJ mice in vivo. Oral Microbiol. Immunol. 23:190-195.
3. Emingil G, Cinarcik S, Baylas H, Huseyinov A. 2001. Levels of plateletactivating factor in gingival crevicular fluid and gingival tissue in specific periodontal diseases. J. Periodontol. 72:1032-1103.
4. Zheng P, Chen H, Shi S, Jepsen S, Eberhard J. 2006. Periodontal parameters and platelet-activating factor levels in serum and gingival crevicular fluid in a Chinese population. J. Clin. Periodontol. 33:797-802.
5. Prescott SM, Zimmerman GA, Stafforini DM, McIntyre TM. 2000. Platelet-activating factor and related lipid mediators. Annu. Rev. Biochem. 69:419-445.
6. Fouda SI, Molski TFP, Ashour MS-E, Sha'afi RI. 1995. Effect of lipopolysaccharide on mitogen-activated protein kinases and cytosolic phospholipase A2. Biochem. J. 308:815-822.
7. Honda Z, Ishii S, Shimizu T. 2002. Platelet activating factor receptor. J. Biochem. 131:773-779.
8. Ishii S, Shimizu T. 2000. Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice. Prog. Lipid. Res. 39:41- 82.
9. Ishii S, Nagase T, Shindou H, Takizawa H, Ouchi Y, Shimizu T. 2004. Platelet-activating factor receptor develops airway hyperresponsiveness independently of airway inflammation in a murine asthma model. J. Immunol. 172:7095-7102.
10. Moreno SE, Alves-Filho JC, Rios-Santos F, Silva JS, Ferreira SH, Cunha FQ, Teixeira MM. 2006. Signaling via platelet-activating factor receptors accounts for the impairment of neutrophil migration in polymicrobial sepsis. J. Immunol. 177:1264-1271.
11. Peplow PV. 1999. Regulation of platelet-activating factor (PAF) activity in human diseases by phospholipase A2 inhibitors, PAF acetylhydrolases, PAF receptor antagonists and free radical scavengers. Prostaglandins Leukot. Essent. Fatty Acids 61:65-82.
12. Castor MG, Rezende BM, Resende CB, Bernardes PT, Cisalpino D, Vieira AT, Souza DG, Silva TA, Teixeira MM, Pinho V. 2012. Plateletactivating factor receptor plays a role in the pathogenesis of graft-versushost disease by regulating leukocyte recruitment, tissue injury, and lethality. J. Leukoc. Biol. 91:629-639.
13. Souza DG, Fagundes CT, Sousa LP, Amaral FA, Souza RS, Souza AL, Kroon EG, Sachs D, Cunha FQ, Bukin E, Atrasheuskaya A, Ignatyev G, Teixeira MM. 2009. Essential role of platelet-activating factor receptor in the pathogenesis of Dengue virus infection. Proc. Natl. Acad. Sci. U. S. A. 106:14138-14143.
14. Souza DG, Pinho V, Soares AC, Shimizu T, Ishii S, Teixeira MM. 2003. Role of PAF receptors during intestinal ischemia and reperfusion injury. A comparative study between PAF receptor-deficient mice and PAF receptor antagonist treatment. Br. J. Pharmacol. 139:733-7340.
15. Hikiji H, Ishii S, Shindou H, Takato T, Shimizu T. 2004. Absence of platelet-activating factor receptor protects mice from osteoporosis following ovariectomy. J. Clin. Investig. 114:85-93.
16. Noguchi K, Morita I, Murota S. 1989. The detection of platelet-activating factor in inflamed human gingival tissue. Arch. Oral Biol. 34:37-41.
17. Waga I, Nakamura M, Honda Z, Ferby I, Toyoshima S, Ishiguro S, Shimizu T. 1993. Two distinct signal transduction pathways for the activation of guinea-pig macrophages and neutrophils by endotoxin. Biochem. Biophys. Res. Commun. 197:465-472.
18. Nakamura M, Honda Z, Waga I, Matsumoto T, Noma M, Shimizu T. 1992. Endotoxin transduces Ca2+ signaling via platelet-activating factor receptor. FEBS Lett. 314:125-129.
19. Wood DA, Hapak LK, Sims SM, Dixon SJ. 1991. Direct effects of platelet-activating factor on isolated rat osteoclasts. J. Biol. Chem. 266: 15369-15376.
20. Madeira MFM, Queiroz-Junior CM, Mitre GC, Campi PS, Silveira EM, Garlet GP, Cisalpino PS, Teixeira MM, Silva TA, Souza DG. 2012. MIF induces osteoclast differentiation and contributes to progression of periodontal disease in mice. Microbes Infect. 14:198-206.
21. Garlet GP, Cardoso CR, Silva TA, Ferreira BR, Avila-Campos MJ, Cunha FQ, Silva JS. 2006. Cytokine pattern determines the progression of experimental periodontal disease induced by Actinobacillus actinomycetemcomitans through the modulation of MMPs, RANKL, and their physiological inhibitors. Oral Microbiol. Immunol. 21:12-20.
22. Waravdekar VS, Saslaw LD. 1959. A sensitive colorimetric method for the estimation of 2-deoxy sugars with the use of the malonaldehydethiobarbituric acid reaction. J. Biol. Chem. 234:1945-1950.
23. Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using realtime quantitative PCR and the 2-δδCt method. Methods 25: 402-408.
24. Fox JG, Dewhirst FE, Fraser GJ, Paster BJ, Shames B, Murphy JC. 1994. Intracellular Campylobacter-like organism from ferrets and hamsters with proliferative bowel disease is a Desulfovibrio sp. J. Clin. Microbiol. 32: 1229-1237.
25. Queiroz-Junior CM, Madeira MFM, Coelho FM, Oliveira CR, Cândido LCM, Garlet GP, Teixeira MM, Souza DG, Silva TA. 2012. Experimental arthritis exacerbates Aggregatibacter actinomycetemcomitans-induced periodontitis in mice. J. Clin. Periodontol. 39:608-616.
26. Kawai T, Paster BJ, Komatsuzawa H, Ernst CW, Gonçalves RB, Sasaki H, Ouhara K, Stashenko PP, Sugai M, Taubman MA. 2007. Crossreactive adaptative immune response to oral commensal bacteria results in an induction of receptor activador of nuclear factor-κB ligand (RANKL)-dependent periodontal bone resorption in a mouse model. Oral Microbiol. Immunol. 22:208-215.
27. Nishida E, Hara Y, Kaneko T, Ikeda Y, Ukai T, Kato I. 2001. Bone resorption and local interleukin-1α and interleukin-1β synthesis induced by Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis lipopolysaccharide. J. Periodontal Res. 36:1-8.
28. Nair SP, Meghji S, Wilson M, Reddi K, White P, Henderson B. 1996. Bacterially induced bone destruction: mechanisms and misconceptions. Infect. Immun. 64:2371-2380.
29. Madeira MFM, Queiroz-Junior CM, Cisalpino D, Werneck SMC, Kikuchi H, Fujise O, Ryffel B, Silva TA, Teixeira MM, Souza DG. 2013. MyD88 is essential for alveolar bone loss induced by Aggregatibacter actinomycetemcomitans LPS in mice. Mol. Oral Microbiol. [Epub ahead of print.] doi:10.1111/omi.12034.
30. Yoshimura A, Hara Y, Kaneko T, Kato I. 1997. Secretion of IL-1β, TNF-α, IL-8 and IL-1ra by human polymorphonuclear leukocytes in response to lipopolysaccharides from periodontapathic bacteria. J. Periodontal Res. 32:279-286.
31. Schenkein HA, Barbour SE, Berry CR, Kipps B, Tew JG. 2000. Invasion of human vascular endothelial cells by Actinobacillus actinomycetemcomitans via the receptor for platelet-activating factor. Infect. Immun. 68: 5416-5419.
32. Hikiji H, Takato T, Shimizu T, Ishii S. 2008. The roles of prostanoids, leukotrienes, and platelet-activating factor in bone metabolism and disease. Prog. Lipid Res. 47:107-126.
33. Shindou H, Ishii S, Yamamoto M, Takeda K, Akira S, Shimizu T. 2005. Priming effect of lipopolysaccharide on acetyl-coenzyme A:lyso-plateletactivating factor acetyltransferase is MyD88 and TRIF independent. J. Immunol. 175:1177-1183.
34. Graves DT, Oates T, Garlet GP. 2011. Review of osteoimmunology and the host response in endodontic and periodontal lesions. J. Oral Microbiol. 3:5304.
35. Garlet GP. 2010. Destructive and protective roles of cytokines in periodontitis: a re-appraisal from host defense and tissue destruction viewpoints. J. Dent. Res. 89:1349-1363.
36. Graves D. 2008. Cytokines that promote periodontal tissue destruction. J. Periodontol. 79(Suppl 8):1585-1591.
37. Hudry-Clergeon H, Stengel D, Ninio E, Vilgrain I. 2005. Plateletactivating factor increases VE-cadherin tyrosine phosphorylation in mouse endothelial cells and its association with the PtdIns3=-kinase. FASEB J. 19:512-520.
38. Prescott SM, McIntyre TM, Zimmerman GA, Stafforini DM. 2002. Sol Sherry lecture in thrombosis: molecular events in acute inflammation. Arterioscler. Thromb. Vasc. Biol. 22:727-733.
39. Honda Z, Nakamura M, Miki I, Minami M, Watanabe T, Seyama Y, Okado H, Toh H, Ito K, Miyamoto T, Shimizu T. 1991. Cloning by functional expression of platelet-activating factor receptor from guineapig lung. Nature 349:342-346.
40. Liu M, Zhu H, Li J, Garcia CC, Feng W, Kirpotina LN, Hilmer J, Tavares LP, Layton AW, Quinn MT, Bothner B, Teixeira MM, Lei B. 2012. Group A Streptococcus secreted esterase hydrolyzes plateletactivating factor to impede neutrophil recruitment and facilitate innate immune evasion. PLoS Pathog. 8:e1002624. doi:10.1371/journal.ppat .1002624.
41. Shaw JO, Pinckard RN, Ferrigni KS, McManus LM, Hanahan DJ. 1981. Activation of human neutrophils with 1-O-hexadecyl/octadecyl-2-acetylsn- glycerol-3-phosphorylcholine (platelet activating factor). J. Immunol. 127:1250-1255.
42. Page RC, Kornman KS. 1997. The pathogenesis of human periodontitis: an introduction. Periodontol. 2000 14:9-11.
43. Soares AC, Pinho VS, Souza DG, Shimizu T, Ishii S, Nicoli JR, Teixeira MM. 2002. Role of the platelet-activating factor (PAF) receptor during pulmonary infection with Gram negative bacteria. Br. J. Pharmacol. 137: 621-628.
44. Okada H, Murakami S. 1998. Cytokine expression in periodontal health and disease. Crit. Rev. Oral Biol. Med. 9:248-266.
45. Kobayashi K, Takahashi N, Jimi E, Udagawa N, Takami M, Kotake S, Nakagawa N, Kinosaki M, Yamaguchi K, Shima N, Yasuda H, Morinaga T, Higashio K, Martin TJ, Suda T. 2000. Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J. Exp. Med. 191:275-286.
46. Kim N, Kadono Y, Takami M, Lee J, Lee SH, Okada F, Kim JH, Kobayashi T, Odgren PR, Nakano H, Yeh WC, Lee SK, Lorenzo JA, Choi Y. 2005. Osteoclast differentiation independent of the TRANCERANK- TRAF6 axis. J. Exp. Med. 202:589-595.
47. Li J, Sarosi I, Yan XQ, Morony S, Capparelli C, Tan HL, McCabe S, Elliott R, Scully S, Van G, Kaufman S, Juan SC, Sun Y, Tarpley J, Martin L, Christensen K, McCabe J, Kostenuik P, Hsu H, Fletcher F, Dunstan CR, Lacey DL, Boyle WJ. 2000. RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism. Proc. Natl. Acad. Sci. U. S. A. 97:1566-1571.