Identification of a cancer stem cell-like side population in the HeLa human cervical carcinoma cell line

Oncology Letters

Volumn 6, Issue 6, 2013, Pages 1673-1680

  Wang, Kefang ^a   Zeng, Jianfang ^b   Luo, Lijing ^b   Yang, Jiaxin ^b   Chen, Jie ^b   Li, Bin ^a   Shen, Keng ^b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

Author keywords

Cancer stem cells; CD133; Cervical carcinoma; HeLa cell line; Side population cells

Indexed keywords

CD133 ANTIGEN; HERMES ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER STEM CELL; CARCINOGENESIS; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DRUG SENSITIVITY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 18; MOUSE; NONHUMAN; UTERINE CERVIX CANCER;

EID: 84886785502     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2013.1607     Document Type: Article

References (30)

1. Reya T, Morrison SJ, Clarke SF and Weissman IL: Stem cells, cancer, and cancer stem cells. Nature 414: 105-111, 2001.
2. Bonnet D and Dick JE: Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 3: 730-737, 1997.
3. Al-Hajj M, Wicha MS, Benito-Hernandez A, et al: Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100: 3983-3988, 2003.
4. Singh SK, Clarke ID, Terasaki M, et al: Identification of a cancer stem cell in human brain tumors. Cancer Res 63: 5821-5828, 2003.
5. Patrawala L, Calhoun T, Schneider-Broussard R, et al: Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells. Oncogene 25: 1696-1708, 2006.
6. Baba T, Convery PA, Matsumura N, et al: Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells. Oncogene 28: 209-218, 2009.
7. Zhang S, Balch C, Chan MW, et al: Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Res 68: 4311-4320, 2008.
8. Goodell MA, Brose K, Paradis G, et al: Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 183: 1797-1806, 1996.
9. Hayashi S, Fujita K, Matsumoto S, et al: Isolation and identification of cancer stem cells from a side population of a human hepatoblastoma cell line, HuH-6 clone-5. Pediatr Surg Int 27: 9-16, 2011.
10. Wang J, Guo LP, Chen LZ, et al: Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line. Cancer Res 67: 3716-3724, 2007.
11. Gao Q, Geng L, Kvalheim G, et al: Identification of cancer stem-like side population cells in ovarian cancer cell line OVCAR-3. Ultrastruct Pathol 33: 175-181, 2009.
12. Kondo T, Setoguchi T and Taga T: Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc Natl Acad Sci USA 101: 781-786, 2004.
13. Storms RW, Goodell MA, Fisher A, et al: Hoechst dye efflux reveals a novel CD7(+)CD34(-) lymphoid progenitor in human umbilical cord blood. Blood 96: 2125-2133, 2000.
14. Iwatani H, Ito T, Imai E, et al: Hematopoietic and nonhematopoietic potentials of Hoechst(low)/side population cells isolated from adult rat kidney. Kidney Int 65: 1604-1614, 2004.
15. Clayton H, Titley I and Vivanco Md: Growth and differentiation of progenitor/stem cells derived from the human mammary gland. Exp Cell Res 297: 444-460, 2004.
16. Ho MM, Ng AV, Lam S and Hung JY: Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res 67: 4827-4833, 2007.
17. Wang J, Guo LP, Chen LZ, et al: Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line. Cancer Res 67: 3716-3724, 2007.
18. Morrison SJ and Kimble J: Asymmetric and symmetric stem-cell divisions in development and cancer. Nature 441: 1068-1074, 2006.
19. Clevers H: Stem cells, asymmetric division and cancer. Nat Genet 37: 1027-1028, 2005.
20. Fürthauer M and González-Gaitan M: Endocytosis, asymmetric cell division, stem cells and cancer: unus pro omnibus, omnes pro uno. Mol Oncol 3: 339-353, 2009.
21. Neumüller RA and Knoblich JA: Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer. Genes Dev 23: 2675-2699, 2009.
22. Dean M, Fojo T and Bates S: Tumour stem cells and drug resistance. Nat Rev Cancer 5:275-284, 2005.
23. Zhou S, Schuetz JD, Bunting KD, et al: The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med 7: 1028-1034, 2001.
24. Balabanov S, Gontarewicz A, Keller G, et al: Abcg2 overexpression represents a novel mechanism for acquired resistance to the multi-kinase inhibitor Danusertib in BCR-ABL-positive cells in vitro. PLoS One 6: e19164, 2011.
25. Ricci-Vitiani L, Lombardi DG, Pilozzi E, et al: Identification and expansion of human colon-cancer-initiating cells. Nature 445: 111-115, 2007.
26. Hermann PC, Huber SL, Herrler T, et al: Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 1: 313-323, 2007.
27. Yang ZF, Ho DW, Ng MN, et al: Significance of CD90+ cancer stem cells in human liver cancer. Cancer Cell 13: 153-166, 2008.
28. Zhou L, Wei X, Cheng L, et al: CD133, one of the markers of cancer stem cells in Hep-2 cell line. Laryngoscope 117: 455-460, 2007.
29. Bao S, Wu Q, McLendon RE, et al: Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444: 756-760, 2006.
30. Zhang S, Balch C, Chan MW, et al: Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Res 68: 4311-4320, 2008.