Protection against peroxynitrite-induced DNA damage by mesalamine: Implications for anti-inflammation and anti-cancer activity

Molecular and Cellular Biochemistry

Volumn 378, Issue 1-2, 2013, Pages 291-298

  Graham, Paul M ^a   Li, Jason Z ^b   Dou, Xueging ^c   Zhu, Hong ^d   Misra, Hara P ^a   Jia, Zhenquan ^e   Li, Yunbo ^d  

^a EDWARD VIA COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

^b Blacksburg High School   (United States)

^c SHANDONG UNIVERSITY   (China)

^d Sampson Regional Medical Center Dermatology Residency Director   (United States)

^e UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

Author keywords

Anti inflammation and anti cancer activity; DNA strand breaks; Mesalamine; Peroxynitrite; SIN 1

Indexed keywords

DOUBLE STRANDED DNA; HYDROXYL RADICAL; LINSIDOMINE; LUMINOL; MESALAZINE; PEROXYNITRITE; PLASMID DNA; SINGLE STRANDED DNA; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; FREE RADICAL; OXYGEN; PEROXYNITROUS ACID; SCAVENGER; VIRUS DNA;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER RISK; CHEMOLUMINESCENCE; COLORECTAL CARCINOMA; CONCENTRATION RESPONSE; DNA DAMAGE; DNA STRAND BREAKAGE; ELECTRON SPIN RESONANCE; HUMAN; OXYGEN CONSUMPTION; SPIN TRAPPING; ULCERATIVE COLITIS; BACTERIOPHAGE PHI X 174; CHEMISTRY; COLORECTAL TUMOR; DOUBLE STRANDED DNA BREAK; GENETICS; OXIDATION REDUCTION REACTION; PLASMID; SINGLE STRANDED DNA BREAK;

ANTI-INFLAMMATORY AGENTS; ANTICARCINOGENIC AGENTS; BACTERIOPHAGE PHI X 174; COLITIS, ULCERATIVE; COLORECTAL NEOPLASMS; DNA BREAKS, DOUBLE-STRANDED; DNA BREAKS, SINGLE-STRANDED; DNA, VIRAL; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICAL SCAVENGERS; FREE RADICALS; HUMANS; MESALAMINE; OXIDATION-REDUCTION; OXYGEN; PEROXYNITROUS ACID; PLASMIDS;

EID: 84886771064     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-013-1620-z     Document Type: Article

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