Major constituents of Bosweilla carteri resin exhibit cyclooxygenase enzyme inhibition and antiproliferative activity

Natural Product Communications

Volumn 8, Issue 10, 2013, Pages 1365-1366

  Alf, Sami I ^a   Zhang, Chuan Rui ^b   Mohamed, Amal A ^a   El Baz, Farouk K ^a   Hegazy, Ahmad K ^c   Kord, Maimona A ^c   Nair, Muraleedharan G ^b  

^a NATIONAL RESEARCH CENTRE   (Egypt)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c CAIRO UNIVERSITY   (Egypt)

Author keywords

Boswellia carteri resin; Cancer chemopreventive agents; Cyclooxygenase inhibitory; Tirucallic acid

Indexed keywords

3 ALPHA O ACETYL 8,24 DIEN TIRUCALLIC ACID; ACETYLSALICYLIC ACID; BOSWELLIA CARTERI EXTRACT; CELECOXIB; CEMBRENE A; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; IBUPROFEN; INCENSOLE; INCENSOLE ACETATE; NAPROXEN; PLANT EXTRACT; RESIN; UNCLASSIFIED DRUG; VERTICILLA 4 (20) 7,11 TRIENE; 3ALPHA-O-ACETYL-8,24-DIEN-TIRUCALLIC ACID; ANTINEOPLASTIC AGENT; CYCLOOXYGENASE 2 INHIBITOR; DITERPENE; PLANT GUM; VERTICILLA-4(20),7,11-TRIENE;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG PURIFICATION; DRUG STRUCTURE; EGYPT; ENZYME INHIBITION; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IC 50; MCF 7 CELL LINE; NONHUMAN; SOLVENT EXTRACTION; TRADITIONAL MEDICINE; BOSWELLIA; CHEMISTRY; DRUG SCREENING; ISOLATION AND PURIFICATION; MEDICINAL PLANT; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BOSWELLIA; CELL LINE, TUMOR; CYCLOOXYGENASE 2 INHIBITORS; DITERPENES; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; PLANT GUMS; PLANTS, MEDICINAL;

EID: 84886768949     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. (a) Mikhaeil BR, Maatooq GT, Badria FA, Amer MMA. (2003) Chemistry and immunomodulatory activity of frankincense oil. Zeitschrift für Naturforschung, 58, 230-238;
2. (b) Banno N, Akihisa T, Yasukawa K, Tokuda H, Tabata K, Nakamura Y, Nishimura R, Kimura Y, Suzuki T. (2006) Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri. Journal of Ethnopharmacology, 107, 249-253;
3. (c) Li F-S, Yan D-L, Liu R-R, Xu K-P, Tan G-S. (2010) Chemical constituents of Boswellia carterii (Frankincense). Chinese Journal of Natural Medicines, 8, 25-27;
4. (d) Basar S, Koch A, Konig WA. (2001) A verticillane-type diterpene from Boswellia carterii essential oil. Flavour and Fragrance Journal, 16, 315-318;
5. (e) Hamm S, Bleton J, Connan J, Tchapla A. (2005) A chemical investigation by headspace SPME and GC-MS of volatile and semi-volatile terpenes in various olibanum samples. Phytochemistry, 66, 1499-1514;
6. (f) Moussaieffa A, Mechoulamb R. (2009) Boswellia resin: from religious ceremonies to medical uses; a review of in-vitro, in-vivo and clinical trials. Journal of Pharmacy and Pharmacology, 61, 1281-1293.
7. (a) Francis JA, Raja SN, Nair MG. (2004) Bioactive terpenoids and guggulusteroids from Commiphora mukul gum resin of potential anti-inflammatory interest. Chemistry & Biodiversity, 1, 1842-1853;
8. (b) Moussaieff A, Shohami E, Kashman Y, Fride E, Schmitz ML, Renner F, Fiebich BL, Munoz E, Ben-Neriah Y, Mechoulam R. (2007) Incensole acetate, a novel anti-inflammatory compound isolated from Boswellia resin, inhibits nuclear factor kappa B activation. Molecular Pharmacology, 72, 1657-1664;
9. (c) Kim KH, Moon E, Kim SY, Choi SU, Lee KR. (2012) Lignan constituents of Tilia amurensis and their biological evaluation on antitumor and anti-inflammatory activities. Food and Chemical Toxicology, 50, 3680-3686;
10. (d) Akihisa T, Tabata K, Banno N, Tokuda H, Nishihara R, Nakamura Y, Kimura Y, Yasukawa K, Suzuki K. (2006) Cancer chemopreventive effects and cytotoxic activities of the triterpene acids from the resin of Boswellia carteri. Biological & Pharmaceutical Bulletin, 29, 1976-1979;
11. (e) Pereg D, Lishner M. (2005) Non-steroidal anti-inflammatory drugs for the prevention and treatment of cancer. Journal of Internal Medicine, 258, 115-123;
12. (f) Harris RE, Beebe-Donk J, Alshafie GA. (2012) Reduction in cancer risk by selective and nonselective cyclooxygenase-2 (COX-2) inhibitors. Journal of Experimental Pharmacology, 4, 91-96.
13. Jayaprakasam B, Vanisree M, Zhang Y, Dewitt DL, Nair MG. (2006) Impact of alkyl esters of caffeic and ferulic acids on tumor cell proliferation, cyclooxygenase enzyme and lipid peroxidation. Journal of Agricultural and Food Chemistry, 54, 5375-5381. (Pubitemid 44195715)
14. (a) Zhang Y, Mills GL, Nair MG. (2003) Cyclooxygenase inhibitory and antioxidant compounds from the fruiting body of an edible mushroom, Agrocybe aegerita. Phytomedicine, 10, 386-390;
15. (b) Ganzera M, Khan IA. (2001) A reversed phase high performance liquid chromatography method for the analysis of boswellic acids in Boswellia serrata. Planta Medica, 67, 778-780.
16. Paul M, Brüning G, Weihrather J, Jauch J. (2011) Qualitative and quantitative analysis of 17 different types of tetra- and pentacyclic triterpenic acids in Boswellia papyrifera by a semi-automatic homomodal 2D HPLC method. Chromatographia, 74, 29-40.
17. Obermann H. (1977) Die chemischen und geruchlichen Unterschiede von Weihrauchharzen. Dragoco Report, 24, 260-265.