The efficacy of targeted intraarterial delivery of concentrated autologous bone marrow containing mononuclear cells in the treatment of osteonecrosis of the femoral head: A five year follow-up study

Bone

Volumn 57, Issue 2, 2013, Pages 509-516

  Mao, Qiang ^a,b,c   Jin, Hongting ^a,c   Liao, Fei ^a,b   Xiao, Luwei ^a,b,c   Chen, Di ^d   Tong, Peijian ^a,b,c  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^c Institute of Orthopaedics and Traumatology of Zhejiang Province   (China)

^d RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Bone marrow; Intraarterial delivery; Medial circumflex femoral artery; Mesenchymal stem cells; Osteonecrosis of the femoral head

Indexed keywords

ADULT; ARTICLE; BONE MARROW BIOPSY; BONE MARROW MONONUCLEAR CELL TRANSPLANTATION; CELL TRANSPLANTATION; COHORT ANALYSIS; DISEASE CLASSIFICATION; DISEASE COURSE; FEMALE; FEMORAL ARTERY; FEMUR HEAD NECROSIS; FOLLOW UP; HARRIS HIP SCORE; HIP RADIOGRAPHY; HUMAN; HUMAN CELL; HUMAN TISSUE; ILIAC CREST; MAJOR CLINICAL STUDY; MALE; MEDIAL FEMORAL CIRCUMFLEX ARTERY; MESENCHYMAL STEM CELL TRANSPLANTATION; PATIENT SAFETY; PHYSIOTHERAPY; SYMPTOM; TOTAL HIP PROSTHESIS; TREATMENT FAILURE; TREATMENT RESPONSE; WEIGHT BEARING;

BONE MARROW; INTRAARTERIAL DELIVERY; MEDIAL CIRCUMFLEX FEMORAL ARTERY; MESENCHYMAL STEM CELLS; OSTEONECROSIS OF THE FEMORAL HEAD;

ADULT; ARTHROPLASTY, REPLACEMENT, HIP; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; FEMALE; FEMUR HEAD NECROSIS; FOLLOW-UP STUDIES; HIP; HUMANS; INJECTIONS, INTRA-ARTERIAL; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; TOMOGRAPHY, X-RAY COMPUTED; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84886725857     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2013.08.022     Document Type: Article

References (37)

1. Li W., Sakai T., Nishii T., Nakamura N., Takao M., Yoshikawa H., et al. Distribution of TRAP-positive cells and expression of HIF-1alpha, VEGF, and FGF-2 in the reparative reaction in patients with osteonecrosis of the femoral head. J Orthop Res 2009, 27:694-700.
2. Cardozo J.B., Andrade D.M., Santiago M.B. The use of bisphosphonate in the treatment of avascular necrosis: a systematic review. Clin Rheumatol 2008, 27:685-688.
3. Lieberman J.R., Engstrom S.M., Meneghini R.M., SooHoo N.F. Which factors influence preservation of the osteonecrotic femoral head?. Clin Orthop Relat Res 2012, 470:525-534.
4. Alves E.M., Angrisani A.T., Santiago M.B. The use of extracorporeal shock waves in the treatment of osteonecrosis of the femoral head: a systematic review. Clin Rheumatol 2009, 28:1247-1251.
5. Johannson H.R., Zywiel M.G., Marker D.R., Jones L.C., McGrath M.S., Mont M.A. Osteonecrosis is not a predictor of poor outcomes in primary total hip arthroplasty: a systematic literature review. Int Orthop 2011, 35:465-473.
6. Marker D.R., Seyler T.M., McGrath M.S., Delanois R.E., Ulrich S.D., Mont M.A. Treatment of early stage osteonecrosis of the femoral head. J Bone Joint Surg Am 2008, 90(Suppl. 4):175-187.
7. Yan Z., Hang D., Guo C., Chen Z. Fate of mesenchymal stem cells transplanted to osteonecrosis of femoral head. J Orthop Res 2009, 27:442-446.
8. Hernigou P., Zilber S., Filippini P., Rouard H., Methieu G., Poignard A. Bone marrow injection in hip osteonecrosis. Tech Orthop 2008, 23:18-25.
9. Wen Q., Ma L., Chen Y.P., Yang L., Luo W., Wang X.N. Treatment of avascular necrosis of the femoral head by hepatocyte growth factor-transgenic bone marrow stromal stem cells. Gene Ther 2008, 15:1523-1535.
10. Zhao D., Cui D., Wang B., Tian F., Guo L., Yang L., et al. Treatment of early stage osteonecrosis of the femoral head with autologous implantation of bone marrow-derived and cultured mesenchymal stem cells. Bone 2012, 50:325-330.
11. Gao Y.S., Zhang C.Q. Cytotherapy of osteonecrosis of the femoral head: a mini review. Int Orthop 2010, 34:779-782.
12. Gangji V., De Maertelaer V., Hauzeur J.P. Autologous bone marrow cell implantation in the treatment of non-traumatic osteonecrosis of the femoral head: five year follow-up of a prospective controlled study. Bone 2011, 49:1005-1009.
13. Wang B.L., Sun W., Shi Z.C., Zhang N.F., Yue D.B., Guo W.S., et al. Treatment of nontraumatic osteonecrosis of the femoral head with the implantation of core decompression and concentrated autologous bone marrow containing mononuclear cells. Arch Orthop Trauma Surg 2010, 130:859-865.
14. Annaloro C., Onida F., Lambertenghi Deliliers G. Autologous hematopoietic stem cell transplantation in autoimmune diseases. Expert Rev Hematol 2009, 2:699-715.
15. Rosato E., Pisarri S., Salsano F. Current strategies for the treatment of autoimmune diseases. J Biol Regul Homeost Agents 2010, 24:251-259.
16. Karussis D., Karageorgiou C., Vaknin-Dembinsky A., Gowda-Kurkalli B., Gomori J.M., Kassis I., et al. Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis. Arch Neurol 2010, 67:1187-1194.
17. Szodoray P., Varoczy L., Szegedi G., Zeher M. Autologous stem cell transplantation in autoimmune and rheumatic diseases: from the molecular background to clinical applications. Scand J Rheumatol 2010, 39:1-11.
18. Mazo M., Planat-Bénard V., Abizanda G., Pelacho B., Léobon B., Gavira J.J., et al. Transplantation of adipose derived stromal cells is associated with functional improvement in a rat model of chronic myocardial infarction. Eur J Heart Fail 2008, 10:454-462.
19. Mazo M., Gavira J.J., Abizanda G., Moreno C., Ecay M., Soriano M., et al. Transplantation of mesenchymal stem cells exerts a greater long-term effect than bone marrow mononuclear cells in a chronic myocardial infarction model in rat. Cell Transplant 2010, 19:313-328.
20. Mark A.L., Sun Z., Warren D.S., Lonze B.E., Knabel M.K., Melville Williams G.M., et al. Stem cell mobilization is life saving in an animal model of acute liver failure. Ann Surg 2010, 252:591-596.
21. Walker P.A., Shah S.K., Jimenez F., Gerber M.H., Xue H., Cutrone R., et al. Intravenous multipotent adult progenitor cell therapy for traumatic brain injury: pre-serving the blood brain barrier via an interaction with splenocytes. Exp Neurol 2010, 225:341-352.
22. Walczak P., Zhang J., Gilad A.A., Kedziorek D.A., Ruiz-Cabello J., Young R.G., et al. Dual-modality monitoring of targeted intraarterial delivery of mesenchymal stem cells after transient ischemia. Stroke 2008, 39(5):1569-1574.
23. Ficat R.P. Idiopathic bone necrosis of femoral head. Early diagnosis and treatment. J Bone Joint Surg Br 1985, 67:3-9.
24. Yoo M.C., Chung D.W., Hahn C.S. Free vascularized fibula grafting for the treatment of osteonecrosis of the femoral head. Clin Orthop Relat Res 1992, 277:128-138.
25. Sotereanos D.G., Plakseychuk A.Y., Rubash H.E. Free vascularized fibula grafting for the treatment of osteonecrosis of the femoral head. Clin Orthop Relat Res 1997, 344:243-256.
26. Agarwala S., Shah S., Joshi V.R. The use of alendronate in the treatment of avascular necrosis of the femoral head: follow-up to eight years. J Bone Joint Surg Br 2009, 91:1013-1018.
27. Feng Y., Yang S.H., Xiao B.J., Xu W.H., Ye S.N., Xia T., et al. Decreased in the number and function of circulation endothelial progenitor cells in patients with avascular necrosis of the femoral head. Bone 2010, 46:32-40.
28. Cui Q., Botchwey E.A. Treatment of precollapse osteonecrosis using stem cells and growth factors. Clin Orthop Relat Res 2011, 469:2665-2669.
29. Li Z.H., Liao W., Cui X.L., Zhao Q., Liu M., Chen Y.H., et al. Intravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head. Int J Med Sci 2011, 8:74-83.
30. Merle D'Aubigné R., Postel M., Mazabraud A., Massias P., Gueguen J., France P. Idiopathic necrosis of the femoral head in adults. J Bone Joint Surg Br 1965, 47:612-633.
31. Patterson R.J., Bichel W.H., Dahlin D.C. Idiopathic necrosis of the head of femur: a study of fifty-two cases. J Bone Joint Surg Am 1964, 46:267-282.
32. Lai K.A., Shen W.J., Yang C.Y., Shao C.J., Hsu J.T., Lin R.M. The use of alendronate to prevent early collapse of femoral head in patients with non traumatic osteonecrosis: a randomized clinical study. J Bone Joint Surg Am 2005, 87:2155-2159.
33. Mont M.A., Hungerford D.S. Non-traumatic avascular necrosis of the femoral head. J Bone Joint Surg Am 1995, 77-A:459-474.
34. Gangji V., Toungouz M., Lambermont M., Bastianelli E., Hauzeur J. Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells: five- year follow-up. Bone 2007, 40:S46-S47.
35. Liu L., Sun Z., Chen B., Han Q., Liao L., Jia M., et al. Ex vivo expansion and in vivo infusion of bone marrow-derived Flk-1+CD31-CD34- mesenchymal stem cells: feasibility and safety from monkey to human. Stem Cells Dev 2006, 15:349-357.
36. Chamberlain G., Fox J., Ashton B., Middleton J. Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing. Stem Cells 2007, 25:2739-2749.
37. Yagi H., Soto-Gutierrez A., Parekkadan B., Kitagawa Y., Tompkins R.G., Kobayashi N., et al. Mesenchymal stem cells: mechanisms of immunomodulation and homing. Cell Transplant 2010, 19:667-679.