Investigation on novel chitosan nanoparticle-aptamer complexes targeting TGF-β receptor II

International Journal of Pharmaceutics

Volumn 456, Issue 2, 2013, Pages 499-507

  Chen, Xia ^a   Zhu, Xiaoyan ^a   Li, Lei ^a   Xian, Guangjun ^a   Wang, Wei ^a   Ma, Dawei ^a   Xie, Lin ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Anti scarring; Aptamer; Chitosan; Human Tenon's capsule fibroblasts; Nanoparticle; TGF

Indexed keywords

APTAMER; CHITOSAN; NANOPARTICLE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; NANOENCAPSULATION; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN TARGETING; SYNTHESIS; ZETA POTENTIAL;

ANTI-SCARRING; APTAMER; CHITOSAN; HUMAN TENON'S CAPSULE FIBROBLASTS; NANOPARTICLE; TGF-Β;

ANIMALS; APTAMERS, NUCLEOTIDE; CATTLE; CELL LINE; CHITOSAN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FIBROBLASTS; HUMANS; NANOPARTICLES; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA;

EID: 84886717068     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.08.028     Document Type: Article

References (34)

1. G.C. Blobe, W.P. Schiemann, and H.F. Lodish Role of transforming growth factor beta in human disease N. Engl. J. Med. 342 2000 1350 1358 (Pubitemid 30408720)
2. P. Calvo, C. Remunan-Lopez, J. Vila-Jato, and M. Alonso Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carriers J. Appl. Polym. Sci. 63 1997 125 132 (Pubitemid 127613982)
3. X.G. Chen, Z. Wang, W.S. Liu, and H.J. Park The effect of carboxymethyl-chitosan on proliferation and collagen secretion of normal and keloid skin fibroblasts Biomaterials 23 2002 4609 4614 (Pubitemid 36151613)
4. M.F. Cordeiro Role of transforming growth factor beta in conjunctival scarring Clin. Sci. (Lond.) 104 2003 181 187 (Pubitemid 36238050)
5. M.F. Cordeiro, S.S. Bhattacharya, G.S. Schultz, and P.T. Khaw TGF-beta1, -beta2, and -beta3 in vitro: biphasic effects on Tenon's fibroblast contraction, proliferation, and migration Invest. Ophthalmol. Vis. Sci. 41 2000 756 763 (Pubitemid 30158886)
6. M.F. Cordeiro, L. Chang, K.S. Lim, J.T. Daniels, R.D. Pleass, D. Siriwardena, and P.T. Khaw Modulating conjunctival wound healing Eye 14 2000 536 547 (Pubitemid 30479758)
7. K. Corsi, F. Chellat, L.H. Yahia, and J.C. Fernandes Mesenchymal stem cells, MG63 and HEK293 transfection using chitosan-DNA nanoparticles Biomaterials 24 2003 1255 1264 (Pubitemid 36069133)
8. A.D. Ellington, and J.W. Szostak In vitro selection of RNA molecules that bind specific ligands Nature 346 1990 818 822
9. G.R. Grotendorst Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts Cytokine Growth Factor Rev. 8 1997 171 179 (Pubitemid 28077925)
10. R. Jayakumar, N. Selvamurugan, S. Nair, S. Tokura, and H. Tamura Preparative methods of phosphorylated chitin and chitosan - an overview Int. J. Biol. Macromol. 43 2008 221 225
11. H. Katas, and H.O. Alpar Development and characterisation of chitosan nanoparticles for siRNA delivery J. Controlled Release 115 2006 216 225 (Pubitemid 44559708)
12. A. Leask, and D.J. Abraham TGF-beta signaling and the fibrotic response FASEB J. 18 2004 816 827
13. T. Lopez-Leon, E.L. Carvalho, B. Seijo, J.L. Ortega-Vinuesa, and D. Bastos-Gonzalez Physicochemical characterization of chitosan nanoparticles: electrokinetic and stability behavior J. Colloid Interface Sci. 283 2005 344 351 (Pubitemid 40254961)
14. C. Lv, H. Dai, X. Xing, and J. Zhang The systematic effects of chitosan on fibroblasts derived from hypertrophic scars and keloids Indian J. Dermatol. Venereol. Leprol. 78 2012 520
15. T. Mairal, V.C. Ozalp, P. Lozano Sanchez, M. Mir, I. Katakis, and C.K. O'Sullivan Aptamers: molecular tools for analytical applications Anal. Bioanal. Chem. 390 2008 989 1007 (Pubitemid 351207799)
16. H.-Q. Mao, K. Roy, V.L. Troung-Le, K.A. Janes, K.Y. Lin, Y. Wang, J.T. August, and K.W. Leong Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency J. Controlled Release 70 2001 399 421 (Pubitemid 32155463)
17. T. Meyer-ter-Vehn, S. Sieprath, B. Katzenberger, S. Gebhardt, F. Grehn, and G. Schlunck Contractility as a prerequisite for TGF-beta-induced myofibroblast transdifferentiation in human tenon fibroblasts Invest. Ophthalmol. Vis. Sci. 47 2006 4895 4904 (Pubitemid 46586390)
18. K. Mladenovska, O. Cruaud, P. Richomme, E. Belamie, R.S. Raicki, M.C. Venier-Julienne, E. Popovski, J.P. Benoit, and K. Goracinova 5-ASA loaded chitosan-Ca-alginate microparticles: preparation and physicochemical characterization Int. J. Pharm. 345 2007 59 69 (Pubitemid 350087541)
19. J.A. Modi, and K. Patel Design, synthesis of some 2,6,9-trisubstituted purinyl thioureido derivatives and evaluation of antimicrobial activity Med. Chem. Res. 21 2012 1660 1664
20. C.A. Stein Phosphorothioate antisense oligodeoxynucleotides: questions of specificity Trends Biotechnol. 14 1996 147 149 (Pubitemid 26162076)
21. R. Stoltenburg, C. Reinemann, and B. Strehlitz SELEX - a (r)evolutionary method to generate high-affinity nucleic acid ligands Biomol. Eng. 24 2007 381 403 (Pubitemid 47391579)
22. G. Sun, X.-Z. Zhang, and C.-C. Chu Formulation and characterization of chitosan-based hydrogel films having both temperature and pH sensitivity J. Mater. Sci.: Mater. Med. 18 2007 1563 1577 (Pubitemid 47033864)
23. P. Tallury, S. Kar, S. Bamrungsap, Y.F. Huang, W. Tan, and S. Santra Ultra-small water-dispersible fluorescent chitosan nanoparticles: synthesis, characterization and specific targeting Chem. Commun. (Camb.) 2009 2347 2349
24. A.I. The The advanced glaucoma intervention study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration Am. J. Ophthalmol. 130 2000 429 440
25. J.J. Tomasek, J. McRae, G.K. Owens, and C.J. Haaksma Regulation of α-smooth muscle actin expression in granulation tissue myofibroblasts is dependent on the intronic CArG element and the transforming growth factor-β1 control element Am. J. Pathol. 166 2005 1343 1351 (Pubitemid 40586506)
26. C. Tuerk, and L. Gold Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase Science 249 1990 505 510
27. B. Urban-Klein, S. Werth, S. Abuharbeid, F. Czubayko, and A. Aigner RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo Gene Ther. 12 2004 461 466 (Pubitemid 40394299)
28. V.V. Venuganti, P. Sahdev, M. Hildreth, X. Guan, and O. Perumal Structure-skin permeability relationship of dendrimers Pharm. Res. 28 2011 2246 2260
29. D. Vllasaliu, R. Exposito-Harris, A. Heras, L. Casettari, M. Garnett, L. Illum, and S. Stolnik Tight junction modulation by chitosan nanoparticles: comparison with chitosan solution Int. J. Pharm. 400 2010 183 193
30. J. Weyermann, D. Lochmann, C. Georgens, and A. Zimmer Albumin-protamine-oligonucleotide-nanoparticles as a new antisense delivery system. Part 2: Cellular uptake and effect Eur. J. Pharm. Biopharm. 59 2005 431 438 (Pubitemid 40342517)
31. H. Ye, Y. Qian, M. Lin, Y. Duan, X. Sun, Y. Zhuo, and J. Ge Cationic nano-copolymers mediated IKKbeta targeting siRNA to modulate wound healing in a monkey model of glaucoma filtration surgery Mol. Vis. 16 2010 2502 2510
32. S. Zhou, X. Deng, and X. Li Investigation on a novel core-coated microspheres protein delivery system J. Controlled Release 75 2001 27 36 (Pubitemid 32635194)
33. J. Zhu, A. Tang, L.P. Law, M. Feng, K.M. Ho, D.K. Lee, F.W. Harris, and P. Li Amphiphilic core-shell nanoparticles with poly(ethylenimine) shells as potential gene delivery carriers Bioconjugate Chem. 16 2005 139 146 (Pubitemid 40129687)
34. X. Zhu, L. Li, L. Zou, G. Xian, H. Li, Y. Tan, and L. Xie A novel aptamer targeting TGF-beta receptor II inhibits transdifferentiation of human tenon's fibroblasts into myofibroblast Invest. Ophthalmol. Vis. Sci. 53 2012 6897 6903