Reprogramming fibroblasts to neural-precursor-like cells by structured overexpression of pallial patterning genes

Molecular and Cellular Neuroscience

Volumn 57, Issue , 2013, Pages 42-53

  Raciti, Marilena ^a   Granzotto, Marilena ^b   Duc, Minh Do ^a   Fimiani, Cristina ^a   Cellot, Giada ^a   Cherubini, Enrico ^a   Mallamaci, Antonello ^a  

^a SISSA   (Italy)

^b INSTITUTE FOR MATERNAL AND CHILD HEALTH IRCCS BURLO GAROFOLO   (Italy)

Author keywords

Cerebral cortex; Fibroblasts reprogramming; Foxg1; Neural stem cells; Neuronal differentiation; Pax6

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EMX2; TRANSCRIPTION FACTOR FOXG1; TRANSCRIPTION FACTOR LHX2; TRANSCRIPTION FACTOR PAX6; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; ASTROCYTE; CELL REPROGRAMMING; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; DNA METHYLATION; EMBRYO; FIBROBLAST; FLUORESCENCE ACTIVATED CELL SORTING; GENE OVEREXPRESSION; GENOTYPE; HEAT SHOCK; IMMUNODETECTION; MEMBRANE STEADY POTENTIAL; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROCEDURES CONCERNING CELLS; SOMATIC CELL; TRANSGENE; UPREGULATION;

(ALLYLAMINO)-17-DEMETHOXYGELDANAMYCIN; 17AAD; BMP; BONE MORPHOGENETIC PROTEIN; CEREBRAL CORTEX; FIBROBLASTS REPROGRAMMING; FL; FOXG1; FOXG1-LHX2; FOXG1-PAX6- LHX2; FOXG1-PAX6-DRUGS; FOXG1-PAX6-EMX2-LHX2; FPD; FPEL; FPL; HDAC; HISTONE DEACETYLASE; HISTONE METHYLTRANSFERASE; HMT; INDUCED PLURIPOTENT STEM CELL; IPSC; MEF; MOI; MOUSE EMBRYONIC FIBROBLAST; MULTIPLICITY OF INFECTION; NEURAL PRECURSOR CELL; NEURAL STEM CELL; NEURAL STEM CELLS; NEURONAL DIFFERENTIATION; NPC; NSC; PAX6; PAX6-LHX2; PL; RESTING MEMBRANE POTENTIAL; RMP; T2PCPA; TF; TGFB; TRANS-2-PHENYL-CYCLOPROPYLAMINE HYDROCHLORIDE; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR B; VALPROIC ACID; VPA;

ANIMALS; BONE MORPHOGENETIC PROTEINS; BRAIN; EYE PROTEINS; FIBROBLASTS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HISTONE DEACETYLASE INHIBITORS; HOMEODOMAIN PROTEINS; LIM-HOMEODOMAIN PROTEINS; MICE; NERVE TISSUE PROTEINS; NEURAL STEM CELLS; NEUROGENESIS; NUCLEAR REPROGRAMMING; PAIRED BOX TRANSCRIPTION FACTORS; REPRESSOR PROTEINS; SOXB1 TRANSCRIPTION FACTORS; TAU PROTEINS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84886527290     PISSN: 10447431     EISSN: 10959327     Source Type: Journal    
DOI: 10.1016/j.mcn.2013.10.004     Document Type: Article

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