Can the antiplatelet effects of cangrelor be reliably studied in mice under in vivo and in vitro conditions using flow cytometry?

Pharmacological Reports

Volumn 65, Issue 4, 2013, Pages 870-883

  Kassassir, Hassan ^a   Siewiera, Karolina ^a   Sychowski, Radoslaw ^a   Watala, Cezary ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

Cangrelor; Flow cytometry; In vitro; In vivo; Laboratory rodents; Mouse platelets; Platelet activation; Platelet reactivity; Washed blood

Indexed keywords

ADENOSINE DIPHOSPHATE; CANGRELOR; COLLAGEN; GLYCOPROTEIN; IMMUNOGLOBULIN G1; LOW MOLECULAR WEIGHT HEPARIN; PADGEM PROTEIN; PURINERGIC P2Y12 RECEPTOR; THROMBIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICOAGULATION; ARTICLE; BLOOD SAMPLING; CELL SUSPENSION; CLINICAL PRACTICE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PLATELET REACTIVITY; PROTEIN EXPRESSION; RELIABILITY; SINGLE DRUG DOSE; THROMBOCYTE ACTIVATION;

ADENOSINE DIPHOSPHATE; ADENOSINE MONOPHOSPHATE; ANIMALS; BLOOD PLATELETS; COLLAGEN; FEMALE; FLOW CYTOMETRY; MICE; MODELS, ANIMAL; P-SELECTIN; PLATELET ACTIVATION; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PURINERGIC P2Y RECEPTOR ANTAGONISTS; THROMBIN;

EID: 84886497288     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/S1734-1140(13)71068-5     Document Type: Article

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