Mechanism of platelet functional changes and effects of anti-platelet agents on in vivo hemostasis under different gravity conditions

Journal of Applied Physiology

Volumn 108, Issue 5, 2010, Pages 1241-1249

  Li, Suping ^a,b   Shi, Quanwei ^a   Liu, Guanglei ^a   Zhang, Weilin ^a   Wang, Zhicheng ^a   Wang, Yuedan ^a,c   Dai, Kesheng ^a  

^a CHINA ASTRONAUT RESEARCH AND TRAINING CENTER   (China)

^b PEKING UNIVERSITY   (China)

^c BEIHANG UNIVERSITY   (China)

Author keywords

Calcium; Cytoskeleton; Hypergravity; Modeled microgravity; Platelets

Indexed keywords

1,2 BIS(2 AMINOPHENOXY)ETHANE N,N,N',N' TETRAACETIC ACID ACETOXYMETHYL ESTER; 1,2-BIS(2-AMINOPHENOXY)ETHANE N,N,N',N'-TETRAACETIC ACID ACETOXYMETHYL ESTER; ACETYLSALICYLIC ACID; ACTIN BINDING PROTEIN; ADENOSINE DIPHOSPHATE; ADHESION RECEPTOR; ANTITHROMBOCYTIC AGENT; CALCIUM; CHELATING AGENT; CONTRACTILE PROTEIN; DIAGNOSTIC AGENT; DRUG DERIVATIVE; EGTAZIC ACID; FILAMINS; MEMBRANE PROTEIN; RISTOCETIN; TIROFIBAN; TYROSINE;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BLOOD; C57BL MOUSE; DRUG EFFECT; GRAVITY; HEMOSTASIS; HUMAN; METABOLISM; MICROFILAMENT; MOUSE; PROTEIN BINDING; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOSIS; TIME; WEIGHTLESSNESS;

ADENOSINE DIPHOSPHATE; ANIMALS; ASPIRIN; BLOOD PLATELETS; CALCIUM; CHELATING AGENTS; CONTRACTILE PROTEINS; EGTAZIC ACID; HEMOSTASIS; HUMANS; HYPERGRAVITY; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICROFILAMENT PROTEINS; MICROFILAMENTS; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PROTEIN BINDING; RISTOCETIN; THROMBOSIS; TIME FACTORS; TYROSINE; WEIGHTLESSNESS SIMULATION;

EID: 77951967553     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01209.2009     Document Type: Article

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