A high performance liquid chromatography fingerprinting and ultra high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry chemical profiling approach to rapidly find characteristic chemical markers for quality evaluation of dispensing granules, a case study on Chuanxiong Rhizoma

Journal of Pharmaceutical and Biomedical Analysis

Volumn 88, Issue , 2014, Pages 391-400

  Zhang, Xiao Lin ^a,b   Liu, Li Fang ^b   Zhu, Ling Ying ^a   Bai, Ying Jia ^a,b   Mao, Qian ^a   Li, Song Lin ^a   Chen, Shi Lin ^d   Xu, Hong Xi ^c  

^a Jiangsu Province Academy of Traditional Chinese Medicine   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

^c SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^d INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

Author keywords

Characteristic chemical marker; Chuanxiong Rhizoma; Dispensing granule; HPLC PDA fingerprinting; UHPLC PDA QTOF MS MS

Indexed keywords

CHINESE DRUG; FERULIC ACID;

ARTICLE; CHINESE HERB; CHUANXIONG RHIZOMA; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG GRANULE; DRUG QUALITY; EVALUATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; QUALITY CONTROL; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET SPECTROSCOPY;

CHARACTERISTIC CHEMICAL MARKER; CHUANXIONG RHIZOMA; DISPENSING GRANULE; HPLC-PDA FINGERPRINTING; UHPLC-PDA-QTOF-MS/MS;

BENZOFURANS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUMARIC ACIDS; MEDICINE, CHINESE TRADITIONAL; PHARMACEUTICAL PREPARATIONS; PLANT EXTRACTS; PLANTS, MEDICINAL; QUALITY CONTROL; REFERENCE STANDARDS; RHIZOME; SOFTWARE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET; TANDEM MASS SPECTROMETRY; TECHNOLOGY, PHARMACEUTICAL;

EID: 84886457943     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2013.09.023     Document Type: Article

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