Household organophosphorus pesticide use and parkinson's disease

International Journal of Epidemiology

Volumn 42, Issue 5, 2013, Pages 1476-1485

  Narayan, Shilpa ^a   Liew, Zeyan ^a   Paul, Kimberly ^a   Lee, Pei Chen ^a   Sinsheimer, Janet S ^b   Bronstein, Jeff M ^b   Ritz, Beate ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

California; Environmental exposures; Household pesticide use; Organophosphorus pesticides; Paraoxonase; Parkinson's disease; united states

Indexed keywords

ARYLDIALKYLPHOSPHATASE; CHLORPYRIFOS; DIMPYLATE; ORGANOPHOSPHATE PESTICIDE; DOMESTIC CHEMICAL; ORGANOPHOSPHORUS COMPOUND; PESTICIDE; PHOSPHOROTHIOIC ACID DERIVATIVE; PON1 PROTEIN, HUMAN;

DATABASE; DETOXIFICATION; ENZYME ACTIVITY; GENETIC VARIATION; HOUSEHOLD SURVEY; OCCUPATIONAL EXPOSURE; ORGANOPHOSPHATE; PESTICIDE; POLLUTION EXPOSURE; REGRESSION ANALYSIS; SENSITIVITY ANALYSIS;

ADULT; ARTICLE; CAUCASIAN; CONTROLLED STUDY; DETOXIFICATION; FEMALE; GENETIC VARIABILITY; GENOTYPE; HOUSEHOLD; HUMAN; HUMAN TISSUE; LONG TERM EXPOSURE; MAJOR CLINICAL STUDY; MALE; PARKINSON DISEASE; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; AGED; CALIFORNIA; CASE CONTROL STUDY; CHEMICALLY INDUCED; ENVIRONMENTAL EXPOSURE; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MIDDLE AGED; ODDS RATIO; PARKINSON DISEASE, SECONDARY; RISK FACTOR; RURAL POPULATION; STATISTICAL MODEL; STATISTICS AND NUMERICAL DATA; VERY ELDERLY;

CALIFORNIA; UNITED STATES;

ADULT; AGED; AGED, 80 AND OVER; ARYLDIALKYLPHOSPHATASE; CALIFORNIA; CASE-CONTROL STUDIES; ENVIRONMENTAL EXPOSURE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HOUSEHOLD PRODUCTS; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; ODDS RATIO; ORGANOPHOSPHORUS COMPOUNDS; ORGANOTHIOPHOSPHATES; PARKINSON DISEASE, SECONDARY; PESTICIDES; RISK FACTORS; RURAL POPULATION;

EID: 84886443430     PISSN: 03005771     EISSN: 14643685     Source Type: Journal    
DOI: 10.1093/ije/dyt170     Document Type: Article

References (45)

1. van der Mark M, Brouwer M, Kromhout H, Nijssen P, Huss A, Vermeulen R. Is pesticide use related to Parkinson disease? Some clues to heterogeneity in study results. Environ Health Perspect 2012;120:340-47.
2. Freire C, Koifman S. Pesticide exposure and Parkinson's disease: Epidemiological evidence of association. Neurotoxicology 2012;33:947-71.
3. Van Maele-Fabry G, Hoet P, Vilain F, Lison D. Occupational exposure to pesticides and Parkinson's disease: A systematic review and meta-analysis of cohort studies. Environ Int 2012;46:30-43.
4. Armes MN, Liew Z, Wang A et al. Residential pesticide usage in older adults residing in Central California. Int J Environ Res Public Health 2011;8:3114-33.
5. Savage EP, Keefe TJ, Wheeler HW et al. Household pesticide usage in the United States. Arch Environ Health 1981; 36:304-09.
6. Stout DM II, Bradham KD, Egeghy PP et al. American Healthy Homes Survey: A national study of residential pesticides measured from floor wipes. Environ Sci Technol 2009;43:4294-300.
7. Gunier RB, Ward MH, Airola M et al. Determinants of agricultural pesticide concentrations in carpet dust. Environ Health Perspect 2011;119:970-76.
8. Gurunathan S, Robson M, Freeman N et al. Accumulation of chlorpyrifos on residential surfaces and toys accessible to children. Environ Health Perspect 1998; 106:9-16.
9. Obendorf SK, Lemley AT, Hedge A, Kline AA, Tan K, Dokuchayeva T. Distribution of pesticide residues within homes in central New York State. Arch Environ Contam Toxicol 2006;50:31-44.
10. Stone DL, Sudakin DL, Jenkins JJ. Longitudinal trends in organophosphate incidents reported to the National Pesticide Information Center, 1995-2007. Environ Health 2009;8:18.
11. Williams MK, Rundle A, Holmes D et al. Changes in pest infestation levels, self-reported pesticide use, and permethrin exposure during pregnancy after the 2000-2001 U.S. Environmental Protection Agency restriction of organophosphates. Environ Health Perspect 2008;116: 1681-88.
12. Dhillon AS, Tarbutton GL, Levin JL et al. Pesticide/Environmental exposures and Parkinson's disease in East Texas. J Agromedicine 2008;13:37-48.
13. Firestone JA, Smith-Weller T, Franklin G, Swanson P, Longstreth WT Jr, Checkoway H. Pesticides and risk of Parkinson disease: A population-based case-control study. Arch Neurol 2005;62:91-95.
14. Hancock DB, Martin ER, Mayhew GM et al. Pesticide exposure and risk of Parkinson's disease: A family-based case-control study. BMC Neurol 2008;8:6.
15. Manthripragada AD, Costello S, Cockburn MG, Bronstein JM, Ritz B. Paraoxonase 1, agricultural organophosphate exposure, and Parkinson disease. Epidemiology 2010;21:87-94.
16. Seidler A, Hellenbrand W, Robra BP et al. Possible environmental, occupational, and other etiologic factors for Parkinson's disease: A case-control study in Germany. Neurology 1996;46:1275-84.
17. Costa LG, Furlong CE. Paraoxonase 1: Structure, function, and polymorphisms. In Satoh T, Gupta RC (eds). Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology. Hoboken, NJ: Wiley, 2010.
18. Costello S, Cockburn M, Bronstein J, Zhang X, Ritz B. Parkinson's disease and residential exposure to maneb and paraquat from agricultural applications in the Central Valley of California. Am J Epidemiol 2009;169: 919-26.
19. Wang A, Costello S, Cockburn M, Zhang X, Bronstein J, Ritz B. Parkinson's disease risk from ambient exposure to pesticides. Eur J Epidemiol 2011;26:547-55.
20. Jacob EL, Gatto NM, Thompson A, Bordelon Y, Ritz B. Occurrence of depression and anxiety prior to Parkinson's disease. Parkinsonism Relat Disord 2010;16: 576-81.
21. Kang GA, Bronstein JM, Masterman DL, Redelings M, Crum JA, Ritz B. Clinical characteristics in early Parkinson's disease in a Central California populationbased study. Mov Disord 2005;20:1133-42.
22. Hughes AJ, Ben-Shlomo Y, Daniel SE, Lees AJ. What features improve the accuracy of clinical diagnosis in Parkinson's disease: A clinicopathologic study. Neurology 2001;57(Suppl 3):S34-38.
23. Liew Z, Wang A, Bronstein J, Ritz B. Job Exposure Matrix (JEM) derived estimates of life-time occupational pesticide exposure and the risk of Parkinson's Disease. Arch Environ Occup Health 2013; doi:10.1080/19338244.2013.778808.
24. California Department of Pesticide Regulation Product/Label Database. (2010); http://www.cdpr.ca.gov/docs/label/prodnam.htm (13 August 2010, date last accessed).
25. Kegley SE, Hill BR, Orme S, Choi AH. Pesticide Action Network PAN Pesticides Database-Chemicals. 2000. www.pesticideinfo.org/Search_Chemicals.jsp (3 November 2010, date last accessed).
26. Siderowf A, Lang AE. Premotor Parkinson's disease: concepts and definitions. Mov Disord 2012;27:608-16.
27. O'Leary KA, Edwards RJ, Town MM, Boobis AR. Genetic and other sources of variation in the activity of serum paraoxonase/diazoxonase in humans: consequences for risk from exposure to diazinon. Pharmacogenet Genomics 2005;15:51-60.
28. Elbaz A, Clavel J, Rathouz PJ et al. Professional exposure to pesticides and Parkinson disease. Ann Neurol 2009;66: 494-504.
29. Barr DB, Wong LY, Bravo R et al. Urinary concentrations of dialkylphosphate metabolites of organophosphorus pesticides: National Health and Nutrition Examination Survey 1999-2004. Int J Environ Res Public Health 2011;8: 3063-98.
30. California Department of Pesticide Regulation. Pesticide Use Reporting-2008 Summary Data. http://www.cdpr.ca.gov/docs/pur/pur08rep/08_pur.htm (1 August 2012, date last accessed).
31. United States Environmental Protection Agency Reregistration Eligibility Decision (RED) for Chlorpyrifos. http://www.epa.gov/pesticides/reregistration/REDs/chlorpyrifos_red.pdf (1 August 2012, date last accessed).
32. United States Environmental Protection Agency Reregistration Eligibility Decision (RED) for Bensulide. http://www.epa.gov/pesticides/reregistration/REDs/bensulide_red.pdf (1 August 2012, date last accessed).
33. Eaton DL, DaroffRB, Autrup H et al. Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment. Crit Rev Toxicol 2008; 38(Suppl 2):1-125.
34. Huen K, Bradman A, Harley K et al. Organophosphate pesticide levels in blood and urine of women and newborns living in an agricultural community. Environ Res 2012;117:8-16.
35. Quirós-Alcalá L, Bradman A, Nishioka M et al. Pesticides in house dust from urban and farmworker households in California: an observational measurement study. Environ Health 2011;10:19.
36. Eddins D, Cerutti D, Williams P, Linney E, Levin ED. Zebrafish provide a sensitive model of persisting neurobehavioral effects of developmental chlorpyrifos exposure: Comparison with nicotine and pilocarpine effects and relationship to dopamine deficits. Neurotoxicol Teratol 2010;32:99-108.
37. Karen DJ, Li W, Harp PR, Gillette JS, Bloomquist JR. Striatal dopaminergic pathways as a target for the insecticides permethrin and chlorpyrifos. Neurotoxicology 2001;22: 811-17.
38. Kaur P, Radotra B, Minz RW, Gill KD. Impaired mitochondrial energy metabolism and neuronal apoptotic cell death after chronic dichlorvos (OP) exposure in rat brain. Neurotoxicology 2007;28:1208-19.
39. Slotkin TA, Levin ED, Seidler FJ. Comparative developmental neurotoxicity of organophosphate insecticides: effects on brain development are separable from systemic toxicity. Environ Health Perspect 2006;114: 746-51.
40. Lee PC, Rhodes SL, Sinsheimer JS, Bronstein J, Ritz B. Functional paraoxonase 1 variants modify the risk of Parkinson's disease due to organophosphate exposure. Environ Int 2013;56:42-47.
41. Cole TB, Walter BJ, Shih DM et al. Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism. Pharmacogenet Genomics 2005;15:589-98.
42. Jansen KL, Cole TB, Park SS, Furlong CE, Costa LG. Paraoxonase 1 (PON1) modulates the toxicity of mixed organophosphorus compounds. Toxicol Appl Pharmacol 2009;236:142-53.
43. Li WF, Costa LG, Richter RJ et al. Catalytic efficiency determines the in-vivo efficacy of PON1 for detoxifying organophosphorus compounds. Pharmacogenetics 2000;10: 767-79.
44. Mackness B, Mackness MI, Arrol S, Turkie W, Durrington PN. Effect of the molecular polymorphisms of human paraoxonase (PON1) on the rate of hydrolysis of paraoxon. Br J Pharmacol 1997;122:265-68.
45. Richter RJ, Jarvik GP, Furlong CE. Determination of Paraoxonase 1 status without the use of toxic organophosphate substrates. Circ Cardiovasc Genet 2008;1: 147-52.