Clonidine suppresses the induction of long-term potentiation by inhibiting HCN channels at the schaffer collateral-ca1 synapse in anesthetized adult rats

Cellular and Molecular Neurobiology

Volumn 33, Issue 8, 2013, Pages 1075-1086

  Li, Chang Jun ^a,b   Zhou, Mei ^a   Li, Hui Ge ^c   Lv, Qing ^a,b   Xu, Xu Lin ^a,b   Guo, Lian Jun ^a,b  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Key Laboratory of Drug Target Research and Pharmacodynamic Evaluation   (China)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Alpha2 adrenoceptors; Hippocampus, HCN channel; LTP

Indexed keywords

4 (N ETHYL N PHENYLAMINO) 1,2 DIMETHYL 6 (METHYLAMINO)PYRIMIDINIUM CHLORIDE; ALPHA 2 ADRENERGIC RECEPTOR; CATION CHANNEL; CLONIDINE; GLUTAMIC ACID; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CATION NONSELECTIVE CHANNEL; UNCLASSIFIED DRUG; YOHIMBINE;

ANESTHESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA PRESSURE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG INHIBITION; FACILITATION; HEART RATE; HIPPOCAMPAL CA1 REGION; IN VIVO STUDY; LONG TERM POTENTIATION; MALE; NERVE CELL CULTURE; NERVE CELL PLASTICITY; NERVE FIBER; NERVE STIMULATION; NONHUMAN; PAIRED PULSE FACILITATION; PRIORITY JOURNAL; RAT; SCHAFFER COLLATERAL; SUPERNATANT; SYNAPTIC INHIBITION; SYNAPTIC TRANSMISSION;

RATTUS;

AGING; ANESTHESIA; ANIMALS; BLOOD PRESSURE; CA1 REGION, HIPPOCAMPAL; CELLS, CULTURED; CLONIDINE; GLUTAMATES; HEART RATE; HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNELS; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENTRICULAR; LONG-TERM POTENTIATION; MALE; NEURONS; PYRIMIDINES; RATS; RATS, SPRAGUE-DAWLEY; SYNAPSES; SYNAPTIC TRANSMISSION; YOHIMBINE;

EID: 84886439083     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-013-9974-z     Document Type: Article

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