Dynamics of serum metabolites in patients with chronic hepatitis C receiving pegylated interferon plus ribavirin: A metabolomics analysis

Metabolism: Clinical and Experimental

Volumn 62, Issue 11, 2013, Pages 1577-1586

  Saito, Takafumi ^a   Sugimoto, Masahiro ^b   Igarashi, Kaori ^b   Saito, Kaori ^b   Shao, Li ^a   Katsumi, Tomohiro ^a   Tomita, Kyoko ^a   Sato, Chikako ^a   Okumoto, Kazuo ^a   Nishise, Yuko ^a   Watanabe, Hisayoshi ^a   Tomita, Masaru ^b   Ueno, Yoshiyuki ^a   Soga, Tomoyoshi ^b  

^a YAMAGATA UNIVERSITY   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

CE TOFMS; Glutathione; HCV; Metabolome; Oxidative stress

Indexed keywords

5 METHOXY 3 INDOLEACETATE; ARGININE; GAMMA BUTYROBETAINE; GAMMA GLUTAMATE; GLUCOSAMINE; GLUTAMIC ACID; GLUTAMINE; GLYCINE; GUANIDOACETATE; INDOLEACETIC ACID; KYNURENINE; LYSINE; METHIONINE SULFOXIDE; PEGINTERFERON ALPHA2B; PYROGLUTAMIC ACID; RIBAVIRIN; TRYPTOPHAN; UNCLASSIFIED DRUG;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BLOOD LEVEL; CAPILLARY ELECTROPHORESIS; CLINICAL ARTICLE; FEMALE; GLUTATHIONE METABOLISM; HEPATITIS C; HUMAN; LIQUID CHROMATOGRAPHY; MALE; METABOLITE; METABOLOMICS; OXIDATIVE STRESS; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; TREATMENT RESPONSE; VIRAL CLEARANCE;

ALANINE AMINOTRANSFERASE; ALT; AREA UNDER THE CURVE; AUC; CAPILLARY ELECTROPHORESIS-TIME-OF-FLIGHT MASS SPECTROMETRY; CE-TOFMS; GLUTATHIONE; HCC; HCV; HEPATITIS C VIRUS; HEPATOCELLULAR CARCINOMA; IDO; IFN; IL; INDOLEAMINE 2,3-DIOXYGENASE; INTERFERON; INTERLEUKIN; METABOLOME; MLR; MRM; MULTIPLE LOGISTIC REGRESSION; MULTIPLE REACTION MONITORING; NON-VIROLOGICAL RESPONSE; NVR; OXIDATIVE STRESS; PC; PEGIFN/RBV; PEGYLATED INTERFERON PLUS RIBAVIRIN; PRINCIPAL COMPONENT; REACTIVE OXYGEN SPECIES; RECEIVER OPERATING CHARACTERISTIC; ROC; ROS; SUSTAINED VIROLOGICAL RESPONSE; SVR;

ADULT; AGED; ANTIVIRAL AGENTS; AREA UNDER CURVE; BETAINE; CARNITINE; CHROMATOGRAPHY, LIQUID; DRUG THERAPY, COMBINATION; FEMALE; GLYCINE; HEPATITIS C, CHRONIC; HUMANS; INTERFERONS; MALE; METABOLOMICS; MIDDLE AGED; POLYETHYLENE GLYCOLS; PRINCIPAL COMPONENT ANALYSIS; RIBAVIRIN; TANDEM MASS SPECTROMETRY; TREATMENT OUTCOME; TRYPTOPHAN; VIRAL LOAD;

EID: 84886411355     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2013.07.002     Document Type: Article

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