Differential regulation of TLR mediated innate immune response of mouse neuronal cells following infection with novel ECSA genotype of Chikungunya virus with and without E1: A226V mutation

Infection, Genetics and Evolution

Volumn 20, Issue , 2013, Pages 396-406

  Priya, Raj ^a   Dhanwani, R ^a   Patro, I K ^b   Rao, P V L ^c   Parida, M M ^a  

^a DEFENCE RESEARCH AND DEVELOPMENT ESTABLISHMENT   (India)

^b JIWAJI UNIVERSITY   (India)

^c BHARATHIAR UNIVERSITY   (India)

Author keywords

Antiviral; Chikungunya; N2a cells; Neuropathogenesis; TLR

Indexed keywords

BETA INTERFERON; PROTEIN ISG 15; PROTEIN MX 2; PROTEIN OAS 3; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 7; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL VIABILITY; CHIKUNGUNYA; CHIKUNGUNYA ALPHAVIRUS; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENE MUTATION; GENOTYPE; IFN BETA GENE; IMMUNOFLUORESCENCE; IMMUNOREGULATION; INNATE IMMUNITY; ISG 15 GENE; MOUSE; MX 2 GENE; NEUROBLASTOMA CELL; NEUROPATHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; OAS 3 GENE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; TNF ALPHA GENE; TOLL LIKE RECEPTOR 3 GENE; TOLL LIKE RECEPTOR 7 GENE; VIRUS CELL INTERACTION; VIRUS MUTANT; VIRUS PATHOGENESIS; VIRUS REPLICATION;

CHIKUNGUNYA VIRUS;

ANTIVIRAL; CHIKUNGUNYA; N2A CELLS; NEUROPATHOGENESIS; TLR;

ALPHAVIRUS INFECTIONS; ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; CHIKUNGUNYA VIRUS; HOST-PATHOGEN INTERACTIONS; IMMUNITY, INNATE; INTERFERON-BETA; MEMBRANE GLYCOPROTEINS; MICE; NEURONS; POLY I-C; RNA, MESSENGER; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 7; TUMOR NECROSIS FACTOR-ALPHA; VIRAL ENVELOPE PROTEINS; VIRUS REPLICATION;

EID: 84886403332     PISSN: 15671348     EISSN: 15677257     Source Type: Journal    
DOI: 10.1016/j.meegid.2013.09.030     Document Type: Article

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