ISG15 is critical in the control of chikungunya virus infection independent of UbE1l mediated conjugation

PLoS Pathogens

Volumn 7, Issue 10, 2011, Pages

  Werneke, Scott W ^a   Schilte, Clementine ^b,c   Rohatgi, Anjali ^a   Monte, Kristen J ^a   Michault, Alain ^d   Arenzana Seisdedos, Fernando ^b,e   Vanlandingham, Dana L ^f   Higgs, Stephen ^g   Fontanet, Arnaud ^b   Albert, Matthew L ^b,c   Lenschow, Deborah J ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INSTITUT PASTEUR   (France)

^c INSERM   (France)

^d Groupe Hospitalier Sud Reunion   (France)

^e CNRS   (France)

^f University of Texas Medical Branch School of Medicine   (United States)

^g KANSAS STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CYTOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERFERON; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 12P40; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN ISG15; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; G1P2 PROTEIN, MOUSE; ISG15 PROTEIN, HUMAN; UBE1L PROTEIN, HUMAN; UBIQUITIN; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CHIKUNGUNYA; CHIKUNGUNYA ALPHAVIRUS; CONJUGATE; CONJUGATION; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; FLOW CYTOMETRY; HOST PATHOGEN INTERACTION; HUMAN; IMMUNE RESPONSE; IMMUNOMODULATION; INFANT; INFECTION CONTROL; INFECTION SENSITIVITY; INNATE IMMUNITY; MALE; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; RETROSPECTIVE STUDY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TH17 CELL; VIRUS LOAD; WILD TYPE; ALPHAVIRUS INFECTION; ANIMAL; C57BL MOUSE; DISEASE MODEL; GENETIC RECOMBINATION; IMMUNOLOGY; METABOLISM; PATHOGENICITY; PHYSIOLOGY; PROTEIN BINDING;

ALPHAVIRUS; CHIKUNGUNYA VIRUS; MUS;

ALPHAVIRUS INFECTIONS; ANIMALS; ANIMALS, NEWBORN; CHIKUNGUNYA VIRUS; CYTOKINES; DISEASE MODELS, ANIMAL; HUMANS; INTERFERON TYPE I; MICE; MICE, INBRED C57BL; PROTEIN BINDING; RECOMBINATION, GENETIC; RETROSPECTIVE STUDIES; UBIQUITIN-ACTIVATING ENZYMES; UBIQUITINS;

EID: 80055100405     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002322     Document Type: Article

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