메뉴 건너뛰기




Volumn 74, Issue 7, 2013, Pages 406-412

Will one size of anticoagulant dosage fit all?

Author keywords

anticoagulants; monitoring; thrombin generation

Indexed keywords

ANTICOAGULANT AGENT; ANTIVITAMIN K; APIXABAN; BLOOD CLOTTING FACTOR 10A INHIBITOR; DABIGATRAN ETEXILATE; EDOXABAN; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; PENTASACCHARIDE; RIVAROXABAN; THROMBIN; THROMBIN INHIBITOR;

EID: 84886396508     PISSN: 02724391     EISSN: 10982299     Source Type: Journal    
DOI: 10.1002/ddr.21097     Document Type: Review
Times cited : (5)

References (56)
  • 1
    • 63149129600 scopus 로고    scopus 로고
    • Assessment of thrombin generation: Useful or hype?
    • Adams M,. 2009. Assessment of thrombin generation: useful or hype? Semin Thromb Hemost 35: 104-110.
    • (2009) Semin Thromb Hemost , vol.35 , pp. 104-110
    • Adams, M.1
  • 2
    • 13244253700 scopus 로고    scopus 로고
    • Thrombin generation for the control of heparin treatment, comparison with the activated partial thromboplastin time
    • Al Dieri R, Alban S, Beguin S, Hemker HC,. 2004. Thrombin generation for the control of heparin treatment, comparison with the activated partial thromboplastin time. J Thromb Haemost 2: 1395-1401.
    • (2004) J Thromb Haemost , vol.2 , pp. 1395-1401
    • Al Dieri, R.1    Alban, S.2    Beguin, S.3    Hemker, H.C.4
  • 3
    • 33644848865 scopus 로고    scopus 로고
    • Fixed dosage of low-molecular-weight heparins causes large individual variation in coagulability, only partly correlated to body weight
    • Al Dieri R, Alban S, Béguin S, Hemker HC,. 2006. Fixed dosage of low-molecular-weight heparins causes large individual variation in coagulability, only partly correlated to body weight. J Thromb Haemost 4: 83-89.
    • (2006) J Thromb Haemost , vol.4 , pp. 83-89
    • Al Dieri, R.1    Alban, S.2    Béguin, S.3    Hemker, H.C.4
  • 5
    • 4644230820 scopus 로고    scopus 로고
    • The Pharmacology and management of the vitamin K antagonists: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    • Ansell J, Hirsh J, Poller L, Bussey H, Jacobson A, Hylek E,. 2004. The Pharmacology and management of the vitamin K antagonists: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 126: 204S-233S.
    • (2004) Chest , vol.126
    • Ansell, J.1    Hirsh, J.2    Poller, L.3    Bussey, H.4    Jacobson, A.5    Hylek, E.6
  • 6
    • 74749103195 scopus 로고    scopus 로고
    • Unraveling the thrombophilia paradox: From hypercoagulability to the prothrombotic state
    • Baglin T,. 2010. Unraveling the thrombophilia paradox: from hypercoagulability to the prothrombotic state. J Thromb Haemost 8: 228-233.
    • (2010) J Thromb Haemost , vol.8 , pp. 228-233
    • Baglin, T.1
  • 7
    • 84875637036 scopus 로고    scopus 로고
    • Large inter-individual variation of the pharmacodynamic effect of anticoagulant drugs on thrombin generation
    • Bloemen S, Hemker HC, Al Dieri R,. 2013. Large inter-individual variation of the pharmacodynamic effect of anticoagulant drugs on thrombin generation. Haematologica 98: 549-554.
    • (2013) Haematologica , vol.98 , pp. 549-554
    • Bloemen, S.1    Hemker, H.C.2    Al Dieri, R.3
  • 9
    • 0038513109 scopus 로고    scopus 로고
    • Effects of melagatran, the active form of the oral direct thrombin inhibitor ximelagatran, and dalteparin on the endogenous thrombin potential in venous blood from healthy male subjects
    • Boström SL, Hansson GF, Kjaer M, Sarich TC,. 2003. Effects of melagatran, the active form of the oral direct thrombin inhibitor ximelagatran, and dalteparin on the endogenous thrombin potential in venous blood from healthy male subjects. Blood Coagul Fibrinolysis 14: 457-462.
    • (2003) Blood Coagul Fibrinolysis , vol.14 , pp. 457-462
    • Boström, S.L.1    Hansson, G.F.2    Kjaer, M.3    Sarich, T.C.4
  • 10
    • 77952733400 scopus 로고    scopus 로고
    • New oral antithrombotics: A need for laboratory monitoring. Against
    • Bounameaux H, Reber G,. 2010. New oral antithrombotics: a need for laboratory monitoring. Against. J Thromb Haemost 8: 627-630.
    • (2010) J Thromb Haemost , vol.8 , pp. 627-630
    • Bounameaux, H.1    Reber, G.2
  • 11
    • 62549086977 scopus 로고    scopus 로고
    • Thrombin generation test in patients under anticoagulant therapy with vitamin K antagonists
    • Brocal I, Marco P, Lucas J, Verdu J, Tarin F,. 2009. Thrombin generation test in patients under anticoagulant therapy with vitamin K antagonists. Thromb Haemost 101: 594-595.
    • (2009) Thromb Haemost , vol.101 , pp. 594-595
    • Brocal, I.1    Marco, P.2    Lucas, J.3    Verdu, J.4    Tarin, F.5
  • 13
    • 84872596433 scopus 로고    scopus 로고
    • Anti-domain i antibodies have a prothrombotic character on coagulation by inhibiting the anticoagulant effect of beta2GPI
    • de Laat B, van Os G, Ninivaggi M, Agar C, de Groot P, Hemker HC, Lindhout T, Meijers J,. 2011. Anti-domain I antibodies have a prothrombotic character on coagulation by inhibiting the anticoagulant effect of beta2GPI. Thromb Haemost 9 (S2): 290-291.
    • (2011) Thromb Haemost , vol.9 , Issue.S2 , pp. 290-291
    • De Laat, B.1    Van Os, G.2    Ninivaggi, M.3    Agar, C.4    De Groot, P.5    Hemker, H.C.6    Lindhout, T.7    Meijers, J.8
  • 14
  • 15
    • 84883812030 scopus 로고    scopus 로고
    • In vitro assessment, using thrombin generation, of the applicability of Prothrombin Complex Concentrate as an antidote for Rivaroxaban
    • Dinkelaar J, Molenaar PJ, Ninivaggi M, de Laat B, Brinkman HJM, Leyte A,. 2013. In vitro assessment, using thrombin generation, of the applicability of Prothrombin Complex Concentrate as an antidote for Rivaroxaban. J Thromb Haemost 11: 1111-1118.
    • (2013) J Thromb Haemost , vol.11 , pp. 1111-1118
    • Dinkelaar, J.1    Molenaar, P.J.2    Ninivaggi, M.3    De Laat, B.4    Brinkman, H.J.M.5    Leyte, A.6
  • 17
    • 84870240173 scopus 로고    scopus 로고
    • Assessment of the impact of rivaroxaban on coagulation assays: Laboratory recommendations for the monitoring of rivaroxaban and review of the literature
    • Douxfils J, Mullier F, Loosen C, Chatelain C, Chatelain B, Dogné JM,. 2012b. Assessment of the impact of rivaroxaban on coagulation assays: laboratory recommendations for the monitoring of rivaroxaban and review of the literature. Thromb Res 130: 956-966.
    • (2012) Thromb Res , vol.130 , pp. 956-966
    • Douxfils, J.1    Mullier, F.2    Loosen, C.3    Chatelain, C.4    Chatelain, B.5    Dogné, J.M.6
  • 18
    • 80053571188 scopus 로고    scopus 로고
    • Reversal of rivaroxaban and dabigatran by prothrombin complex concentrat: A randomized, placebo-controlled, crossover study in healthy subjects
    • Eerenberg ES, Kamphuisen PW, Sijpkens MK, Meijers JC, Buller HR, Levi M,. 2011. Reversal of rivaroxaban and dabigatran by prothrombin complex concentrat: a randomized, placebo-controlled, crossover study in healthy subjects. Circulation 124: 1573-1579.
    • (2011) Circulation , vol.124 , pp. 1573-1579
    • Eerenberg, E.S.1    Kamphuisen, P.W.2    Sijpkens, M.K.3    Meijers, J.C.4    Buller, H.R.5    Levi, M.6
  • 19
    • 33751252564 scopus 로고    scopus 로고
    • Monitoring unfractionated heparin with the aPTT: Time for a fresh look
    • Eikelboom JW, Hirsh J,. 2006. Monitoring unfractionated heparin with the aPTT: time for a fresh look. Thromb Haemost 96: 547-552.
    • (2006) Thromb Haemost , vol.96 , pp. 547-552
    • Eikelboom, J.W.1    Hirsh, J.2
  • 22
    • 34548575058 scopus 로고    scopus 로고
    • Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: A randomised, double-blind, non-inferiority trial
    • et al.:. [Erratum, Lancet 2007; 370:2004.].
    • Eriksson BI, Dahl OE, Rosencher N, Kurth AA, van Dijk CN, Frostick SP, Prins MH, Hettiarachchi R, Hantel S, Schnee J, et al. 2007b. Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial. Lancet 370: 949-956. [Erratum, Lancet 2007; 370:2004.].
    • (2007) Lancet , vol.370 , pp. 949-956
    • Eriksson, B.I.1    Dahl, O.E.2    Rosencher, N.3    Kurth, A.A.4    Van Dijk, C.N.5    Frostick, S.P.6    Prins, M.H.7    Hettiarachchi, R.8    Hantel, S.9    Schnee, J.10
  • 23
    • 33748156096 scopus 로고    scopus 로고
    • ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation-executive summary: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients with Atrial Fibrillation)
    • et al.
    • Fuster V, Rydén LE, Cannom DS, Crijns HJ, Curtis AB, Ellenbogen KA, Halperin JL, Le Heuzey JY, Kay GN, Lowe JE, et al. 2006. ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation-executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients with Atrial Fibrillation). Eur Heart J 27: 1979-2030.
    • (2006) Eur Heart J , vol.27 , pp. 1979-2030
    • Fuster, V.1    Rydén, L.E.2    Cannom, D.S.3    Crijns, H.J.4    Curtis, A.B.5    Ellenbogen, K.A.6    Halperin, J.L.7    Le Heuzey, J.Y.8    Kay, G.N.9    Lowe, J.E.10
  • 24
    • 48949087350 scopus 로고    scopus 로고
    • Thrombin generation assays are superior to traditional tests in assessing anticoagulation reversal in vitro
    • Gatt A, van Veen JJ, Woolley AM, Kitchen S, Cooper P, Makris M,. 2008. Thrombin generation assays are superior to traditional tests in assessing anticoagulation reversal in vitro. Thromb Haemost 100: 350-355.
    • (2008) Thromb Haemost , vol.100 , pp. 350-355
    • Gatt, A.1    Van Veen, J.J.2    Woolley, A.M.3    Kitchen, S.4    Cooper, P.5    Makris, M.6
  • 25
    • 46049090201 scopus 로고    scopus 로고
    • Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
    • Geerts WH, Bergqvist D, Pineo GF, Heit JA, Samama CM, Lassen MR, Colwell CW,. 2008. Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 133: 381S-453S.
    • (2008) Chest , vol.133
    • Geerts, W.H.1    Bergqvist, D.2    Pineo, G.F.3    Heit, J.A.4    Samama, C.M.5    Lassen, M.R.6    Colwell, C.W.7
  • 26
    • 4644288189 scopus 로고    scopus 로고
    • Prevention of venous thromboembolism: The Seventh ACCP Conference on Anti- thrombotic and Thrombolytic Therapy
    • Geerts WH, Pineo GF, Heit JA, Bergqvist D, Lassen MR, Colwell CW, Ray JG,. 2004. Prevention of venous thromboembolism: the Seventh ACCP Conference on Anti- thrombotic and Thrombolytic Therapy. Chest 126: 338S-400S.
    • (2004) Chest , vol.126
    • Geerts, W.H.1    Pineo, G.F.2    Heit, J.A.3    Bergqvist, D.4    Lassen, M.R.5    Colwell, C.W.6    Ray, J.G.7
  • 27
    • 0026580091 scopus 로고
    • Pulmonary embolism thrombolysis: A clarion call for international collaboration
    • Goldhaber SZ,. 1992. Pulmonary embolism thrombolysis: a clarion call for international collaboration. J Am Coll Cardiol 19: 246-247.
    • (1992) J Am Coll Cardiol , vol.19 , pp. 246-247
    • Goldhaber, S.Z.1
  • 28
    • 84855402737 scopus 로고    scopus 로고
    • Newer oral anticoagulants should be used as first-line agents to prevent thromboembolism in patients with atrial fibrillation and risk factors for stroke or thromboembolism
    • Granger CB, Armaganijan LV,. 2012. Newer oral anticoagulants should be used as first-line agents to prevent thromboembolism in patients with atrial fibrillation and risk factors for stroke or thromboembolism. Circulation 125: 159-164.
    • (2012) Circulation , vol.125 , pp. 159-164
    • Granger, C.B.1    Armaganijan, L.V.2
  • 29
    • 0036145979 scopus 로고    scopus 로고
    • Limitations of the laboratory monitoring of heparin therapy. Scientific and Standardization Committee Communications: On behalf of the Control of Anticoagulation Subcommittee of the Scientific and Standardization Committee of the International Society of Thrombosis and Haemostasis
    • Greaves M,. 2002. Limitations of the laboratory monitoring of heparin therapy. Scientific and Standardization Committee Communications: on behalf of the Control of Anticoagulation Subcommittee of the Scientific and Standardization Committee of the International Society of Thrombosis and Haemostasis. Thromb Haemost 87: 163-164.
    • (2002) Thromb Haemost , vol.87 , pp. 163-164
    • Greaves, M.1
  • 30
    • 0037669041 scopus 로고    scopus 로고
    • The pharmacodynamics and pharmacokinetics of the oral direct thrombin inhibitor ximelagatran and its active metabolite melagatran: A mini-review
    • Gustafsson D, Elg M,. 2003. The pharmacodynamics and pharmacokinetics of the oral direct thrombin inhibitor ximelagatran and its active metabolite melagatran: a mini-review. Thromb Res 109 (Suppl 1): S9-15.
    • (2003) Thromb Res , vol.109 , Issue.SUPPL. 1
    • Gustafsson, D.1    Elg, M.2
  • 31
    • 78650511502 scopus 로고    scopus 로고
    • Inter-individual variability of effect of 7 low molecular weight antithrombin-dependent anticoagulants studied in vitro with Calibrated Automated Thrombography
    • Hacquard M, Perrin J, Lelievre N, Vigneron C, Lecompte T,. 2010. Inter-individual variability of effect of 7 low molecular weight antithrombin-dependent anticoagulants studied in vitro with Calibrated Automated Thrombography. Thromb Res 127: 29-34.
    • (2010) Thromb Res , vol.127 , pp. 29-34
    • Hacquard, M.1    Perrin, J.2    Lelievre, N.3    Vigneron, C.4    Lecompte, T.5
  • 32
    • 0033527355 scopus 로고    scopus 로고
    • Antithrombotic therapy to prevent stroke in patients with atrial fibrillation: A meta-analysis
    • Hart RG, Benavente O, McBride R, Pearce LA,. 1999. Antithrombotic therapy to prevent stroke in patients with atrial fibrillation: a meta-analysis. Ann Intern Med 131: 492-501.
    • (1999) Ann Intern Med , vol.131 , pp. 492-501
    • Hart, R.G.1    Benavente, O.2    McBride, R.3    Pearce, L.A.4
  • 35
    • 33746453363 scopus 로고    scopus 로고
    • Identification of patients at low risk for recurrent venous thromboembolism by measuring thrombin generation
    • Hron G, Kollars M, Binder BR, Eichinger S, Kyrle PA,. 2006. Identification of patients at low risk for recurrent venous thromboembolism by measuring thrombin generation. JAMA 296: 397-402.
    • (2006) JAMA , vol.296 , pp. 397-402
    • Hron, G.1    Kollars, M.2    Binder, B.R.3    Eichinger, S.4    Kyrle, P.A.5
  • 36
    • 34249715284 scopus 로고    scopus 로고
    • Major hemorrhage and tolerability of warfarin in the first year of therapy among elderly patients with atrial fibrillation
    • Hylek EM, Evans-Molina C, Shea C, Henault LE, Regan S,. 2007. Major hemorrhage and tolerability of warfarin in the first year of therapy among elderly patients with atrial fibrillation. Circulation 115: 2689-2696.
    • (2007) Circulation , vol.115 , pp. 2689-2696
    • Hylek, E.M.1    Evans-Molina, C.2    Shea, C.3    Henault, L.E.4    Regan, S.5
  • 37
    • 84875977824 scopus 로고    scopus 로고
    • Moving toward a more ideal anticoagulant: The oral direct thrombin and factor xa inhibitors
    • King CS, Holley AB, Moores LK,. 2013. Moving toward a more ideal anticoagulant: the oral direct thrombin and factor xa inhibitors. Chest 143: 1106-1116.
    • (2013) Chest , vol.143 , pp. 1106-1116
    • King, C.S.1    Holley, A.B.2    Moores, L.K.3
  • 40
    • 80052413972 scopus 로고    scopus 로고
    • Bleeding risk and reversal strategies for old and new anticoagulants and antiplatelet agents
    • Levi M, Eerenberg E, Kamphuisen PW,. 2011. Bleeding risk and reversal strategies for old and new anticoagulants and antiplatelet agents. J Thromb Haemost 9: 1705-1712.
    • (2011) J Thromb Haemost , vol.9 , pp. 1705-1712
    • Levi, M.1    Eerenberg, E.2    Kamphuisen, P.W.3
  • 43
    • 77952679761 scopus 로고    scopus 로고
    • New oral antithrombotics: A need for laboratory monitoring. for
    • Mismetti P, Laporte S,. 2010. New oral antithrombotics: a need for laboratory monitoring. For. J Thromb Haemost 8: 621-626.
    • (2010) J Thromb Haemost , vol.8 , pp. 621-626
    • Mismetti, P.1    Laporte, S.2
  • 44
    • 84867826077 scopus 로고    scopus 로고
    • Measuring Rivaroxaban in a clinical laboratory setting, using common coagulation assays, Xa inhibition and thrombin generation
    • Molenaar PJ, Dinkelaar J, Leyte A,. 2012. Measuring Rivaroxaban in a clinical laboratory setting, using common coagulation assays, Xa inhibition and thrombin generation. Clin Chem Lab Med 50: 1799-1807.
    • (2012) Clin Chem Lab Med , vol.50 , pp. 1799-1807
    • Molenaar, P.J.1    Dinkelaar, J.2    Leyte, A.3
  • 45
    • 51349095537 scopus 로고    scopus 로고
    • Population pharmacokinetics and pharmacodynamics of once- and twice-daily rivaroxaban for the prevention of venous thromboembolism in patients undergoing total hip replacement
    • Mueck W, Borris LC, Dahl OE, Haas S, Huisman MV, Kakkar AK, Kalebo P, Muelhofer E, Misselwitz F, Eriksson BI,. 2008. Population pharmacokinetics and pharmacodynamics of once- and twice-daily rivaroxaban for the prevention of venous thromboembolism in patients undergoing total hip replacement. Thromb Haemost 100: 453-461.
    • (2008) Thromb Haemost , vol.100 , pp. 453-461
    • Mueck, W.1    Borris, L.C.2    Dahl, O.E.3    Haas, S.4    Huisman, M.V.5    Kakkar, A.K.6    Kalebo, P.7    Muelhofer, E.8    Misselwitz, F.9    Eriksson, B.I.10
  • 46
    • 0029059269 scopus 로고
    • Randomised comparison of subcutaneous heparin, intravenous heparin, and aspirin in unstable angina. Studio Epoorine Sottocutanea nell'Angina Instobile (SESAIR) Refrattorie Group
    • Neri Serneri GG, Modesti PA, Gensini GF, Branzi A, Melandri G, Poggesi L, Rostagno C, Tamburini C, Carnovali M, Magnani B,. 1995. Randomised comparison of subcutaneous heparin, intravenous heparin, and aspirin in unstable angina. Studio Epoorine Sottocutanea nell'Angina Instobile (SESAIR) Refrattorie Group. Lancet 345: 1201-1204.
    • (1995) Lancet , vol.345 , pp. 1201-1204
    • Neri Serneri, G.G.1    Modesti, P.A.2    Gensini, G.F.3    Branzi, A.4    Melandri, G.5    Poggesi, L.6    Rostagno, C.7    Tamburini, C.8    Carnovali, M.9    Magnani, B.10
  • 49
    • 0029914728 scopus 로고    scopus 로고
    • Inhibition of platelet-mediated, tissue factor-induced thrombin generation by the mouse/ human chimeric 7E3 antibody. Potential implications for the effect of c7E3 Fab treatment on acute thrombosis and "clinical restenosis"
    • Reverter JC, Beguin S, Kessels H, Kumar R, Hemker HC, Coller BS,. 1996. Inhibition of platelet-mediated, tissue factor-induced thrombin generation by the mouse/ human chimeric 7E3 antibody. Potential implications for the effect of c7E3 Fab treatment on acute thrombosis and "clinical restenosis". J Clin Invest 98: 863-874.
    • (1996) J Clin Invest , vol.98 , pp. 863-874
    • Reverter, J.C.1    Beguin, S.2    Kessels, H.3    Kumar, R.4    Hemker, H.C.5    Coller, B.S.6
  • 50
    • 59349093707 scopus 로고    scopus 로고
    • Is thrombin generation the new rapid, reliable and relevant pharmacological tool for the development of anticoagulant drugs?
    • Robert S, Ghiotto J, Pirotte B, David JL, Masereel B, Pochet L, Dogne JM,. 2009. Is thrombin generation the new rapid, reliable and relevant pharmacological tool for the development of anticoagulant drugs? Pharmacol Res 59: 160-166.
    • (2009) Pharmacol Res , vol.59 , pp. 160-166
    • Robert, S.1    Ghiotto, J.2    Pirotte, B.3    David, J.L.4    Masereel, B.5    Pochet, L.6    Dogne, J.M.7
  • 51
    • 0029023726 scopus 로고
    • Can overall results of clinical trials be applied to all patients?
    • Rothwell PM,. 1995. Can overall results of clinical trials be applied to all patients? Lancet 345: 1616-1619.
    • (1995) Lancet , vol.345 , pp. 1616-1619
    • Rothwell, P.M.1
  • 52
    • 84859178003 scopus 로고    scopus 로고
    • How i treat with anticoagulants in 2012: New and old anticoagulants, and when and how to switck
    • Schulman S, Crowther MA,. 2012. How I treat with anticoagulants in 2012: new and old anticoagulants, and when and how to switck. Blood 119: 3016-3023.
    • (2012) Blood , vol.119 , pp. 3016-3023
    • Schulman, S.1    Crowther, M.A.2
  • 53
    • 63149098718 scopus 로고    scopus 로고
    • Laboratory monitoring of anticoagulation: Where do we stand?
    • Tripodi A, van den Besselaar A,. 2009. Laboratory monitoring of anticoagulation: where do we stand? Semin Thromb Hemost 35: 34-41.
    • (2009) Semin Thromb Hemost , vol.35 , pp. 34-41
    • Tripodi, A.1    Van Den Besselaar, A.2
  • 54
    • 51849182428 scopus 로고
    • Standardization of the activated partial thromboplastin time for monitoring of heparin therapy: Where should we go?
    • van den Besselaar A,. 1989. Standardization of the activated partial thromboplastin time for monitoring of heparin therapy: where should we go? Ric Clin Lab 19: 371-377.
    • (1989) Ric Clin Lab , vol.19 , pp. 371-377
    • Van Den Besselaar, A.1
  • 55
    • 50049135947 scopus 로고    scopus 로고
    • Thrombin generation testing in routine clinical practice: Are we there yet?
    • van Veen JJ, Gatt A, Makris M,. 2008. Thrombin generation testing in routine clinical practice: are we there yet? Br J Haematol 142: 889-903.
    • (2008) Br J Haematol , vol.142 , pp. 889-903
    • Van Veen, J.J.1    Gatt, A.2    Makris, M.3
  • 56


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.